检索结果-南通市图书馆

概率论缘何没有起源于中国——基于赌博史的中西方考察

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

自然辩证法研究 2017年第12期33卷 77-80页

作者：胡顺奇枣庄学院经济管理学院山东枣庄277160

概率论在17世纪中叶起源于西方机会性赌博活动,有久远赌博历史的中国与概率论创立无缘,主要在于中西方赌博的目的、种类,对待赌博的态度、看待赌博结果等方面存在巨大差异,这种差异是对概率论缘何首先在西方而非中国起源的最好解释。概... 详细信息

概率论在17世纪中叶起源于西方机会性赌博活动,有久远赌博历史的中国与概率论创立无缘,主要在于中西方赌博的目的、种类,对待赌博的态度、看待赌博结果等方面存在巨大差异,这种差异是对概率论缘何首先在西方而非中国起源的最好解释。概率论远滞后赌博起源是受其社会文化、道德及计算技术等因素的制约。

关键词：机会赌博概率

Comparative Analysis of Two Local Heavy Rainstorms in Northwestern Shandong

在线全文

学校读者我要写书评

暂无评论

Meteorological and Environmental Research 2011年第9期2卷 24-27页

作者： Zhu Yi-qing CAO Xing-feng LIU Ying-jie SUN Chang-zheng hu shun-qi Linyi Meteorological Bureau of Shandong Province Linyi 276004China Jinan Meteorological Bureau of Shandong Province Jinan 250002China

[Objective] The aim was to comparatively analyze two local heavy rainstroms in northwestern Shandong Province, China. [Method] Based on the observation data from automatic weather station, sounding data and NCEP reanalysis data, two local heavy rainstorms at night on July 18 and August 9 in 2010 in northwestern Shandong was comparatively analyzed from the aspects of circulation situation, influence system and physical field, and the internal structure and possible formation mechanism of local heavy rain in Shandong were discussed further. [Result] The two rainstorms occurred in the forepart of southwest air in front of 500 hPa trough, and there was stronger atmospheric baroclinicity in the front zone near 850 hPa. The two rainstorms were affected by southwest warm and humid airflow at low level and shear line at 850 hPa; rainstorm often appeared in intensive area behind θse high-energy tongue, and rainstorm area corresponded with the area with high vertical speed well. From the differences, during the first rainstorm, there was obvious southwest low level jet and shear line at 700 hPa, and the area with high precipitation was located in the south of warm shear line at 700 hPa; during the latter rainstorm, there was no obvious southwest low level jet and shear line, and the area with high precipitation was located in the region between two high pressures. [Conclusion] The study could provide valuable thinking for the forecast of this kind of rainstorm in the future.

关键词： Local heavy rainstorms Weather process Comparative analysis Northwestern Shandong China

Potential role of tanycyte-derived neurogenesis in Alzheimer's disease

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1599-1612页

作者： Guibo qi Han Tang Jianian hu Siying Kang Song qin Department of Anatomy Histologyand EmbryologySchool of Basic Medical SciencesFudan UniversityShanghaiChina State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Fudan UniversityShanghaiChina

Tanycytes, specialized ependymal cells located in the hypothalamus, play a crucial role in the generation of new neurons that contribute to the neural circuits responsible for regulating the systemic energy balance. The precise coordination of the gene networks controlling neurogenesis in naive and mature tanycytes is essential for maintaining homeostasis in adulthood. However, our understanding of the molecular mechanisms and signaling pathways that govern the proliferation and differentiation of tanycytes into neurons remains limited. This article aims to review the recent advancements in research into the mechanisms and functions of tanycyte-derived neurogenesis. Studies employing lineage-tracing techniques have revealed that the neurogenesis specifically originating from tanycytes in the hypothalamus has a compensatory role in neuronal loss and helps maintain energy homeostasis during metabolic diseases. Intriguingly,metabolic disorders are considered early biomarkers of Alzheimer's disease. Furthermore,the neurogenic potential of tanycytes and the state of newborn neurons derived from tanycytes heavily depend on the maintenance of mild microenvironments, which may be disrupted in Alzheimer's disease due to the impaired blood–brain barrier ***, the specific alterations and regulatory mechanisms governing tanycyte-derived neurogenesis in Alzheimer's disease remain unclear. Accumulating evidence suggests that tanycyte-derived neurogenesis might be impaired in Alzheimer's disease, exacerbating neurodegeneration. Confirming this hypothesis, however, poses a challenge because of the lack of long-term tracing and nucleus-specific analyses of newborn neurons in the hypothalamus of patients with Alzheimer's disease. Further research into the molecular mechanisms underlying tanycyte-derived neurogenesis holds promise for identifying small molecules capable of restoring tanycyte proliferation in neurodegenerative diseases. This line of investigation could pro

关键词： Alzheimer's disease blood–brain barrier ependymoglial cells hypothalamus metabolic diseases neural stem cells neurogenesis neuroinflammatory diseases neurons tanycyte

CO2-mediated bicarbonate conversion to concentrated formate in a CEM-based electrolyzer

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 605-611页

作者： Haocheng Xiong Donghuan Wu Haonan Li Andrew Li qikun hu Siyao Song Bingjun Xu qi Lu State Key Laboratory of Chemical Engineering Department of Chemical Engineering Tsinghua University College of Chemistry and Molecular Engineering Peking University Ordos Laboratory

Renewable energy-driven bicarbonate conversion to valuable chemicals presents an attractive strategy for mitigating CO2emissions,as bicarbonate can be efficiently generated from the capture of atmospheric CO2using alkaline solutions with reactive *** this work,we present a CO2-mediated bicarbonate conversion to pure formate using a cation exchange membrane-based electrolyzer with a 25 cm2electrode *** electrolysis achieved selectivities exceeding 75%for formate at a total current of 2.5 A,achieving formate concentrations up to 1.2 M and yields as high as 95%over extended *** techno-economic assessment confirmed the economic viability of the process,highlighting the potential for bicarbonate electrolysis as a sustainable method for producing valuable chemicals.

关键词： Electrocatalysis Techno-economic assessments Electrochemistry Flow electrolyzer

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

社会经济统计数据失真分析

枣庄学院学报 2013年第1期30卷 78-81页

作者：胡顺奇枣庄学院经济与管理学院山东枣庄277160

目前社会经济统计数据失真已造成许多不良影响,引起各方高度关注。本文在说明统计数据失真给社会带来严重危害的基础上,从认识、体制、法制及数据搜集等方面存在的问题分析了导致数据失真的原因。从提高认识、改革体制、加强法制、科学... 详细信息

目前社会经济统计数据失真已造成许多不良影响,引起各方高度关注。本文在说明统计数据失真给社会带来严重危害的基础上,从认识、体制、法制及数据搜集等方面存在的问题分析了导致数据失真的原因。从提高认识、改革体制、加强法制、科学搜集原始数据等方面提出了治理统计数据失真的对策。

关键词：数据失真危害成因对策

在线全文

学校读者我要写书评

暂无评论

社会资本对加拿大移民就业的影响研究

枣庄学院学报 2014年第2期31卷 120-125页

作者：公维丽胡顺奇枣庄学院经济与管理学院山东枣庄277160

加拿大是世界典型的移民国家,移民对加拿大社会经济的发展做出了不可磨灭的贡献.通过纵向调查加拿大移民,利用各种社会资本和人力资本作为劳动力市场一体化的指标,考察了它们在加拿大新移民劳动力市场一体化的作用.结果表明社会资本很... 详细信息

加拿大是世界典型的移民国家,移民对加拿大社会经济的发展做出了不可磨灭的贡献.通过纵向调查加拿大移民,利用各种社会资本和人力资本作为劳动力市场一体化的指标,考察了它们在加拿大新移民劳动力市场一体化的作用.结果表明社会资本很大程度有助于增加就业的可能性和提高社会经济规模(SES),但社会资本的作用受本身类型和人力资本、移民的种族和经济一体化形式的制约和影响.

关键词：社会资本就业职业地位移民

在线全文

学校读者我要写书评

暂无评论

自噬对椎间盘退行性变作用机制的研究进展

脊柱外科杂志 2020年第6期18卷 414-418页

作者：胡舜琪张其琛李熙雷复旦大学附属中山医院骨科上海200032

椎间盘退行性变(IDD)被公认为是腰痛的主要原因,约有80%的人会在其一生中遭遇到腰痛[1]。目前,世界上约有6.5亿人受到腰痛的困扰,仅在美国,每年投入的相关费用就超过了300亿美元,甚至超过了中风、呼吸道感染、糖尿病、冠状动脉疾病及类... 详细信息

椎间盘退行性变(IDD)被公认为是腰痛的主要原因,约有80%的人会在其一生中遭遇到腰痛[1]。目前,世界上约有6.5亿人受到腰痛的困扰,仅在美国,每年投入的相关费用就超过了300亿美元,甚至超过了中风、呼吸道感染、糖尿病、冠状动脉疾病及类风湿疾病的费用总和[2]。腰痛已是导致患者住院治疗的第二大常见病因,也是导致患者长期残疾的主要原因之一[3]。此外,IDD还是颈部和背部疼痛综合征的主要原因,严重情况下甚至会造成患者残疾[4]。随着人口老龄化的日渐加重,IDD对人类健康造成巨大危害,也给患者家庭和社会增加了沉重的经济负担。作为一种常见的复杂退行性疾病,其传统治疗措施已无法满足目前的临床需求。自噬细胞保护效应引起学者们的关注。椎间盘髓核细胞通过自噬适应外界环境,维持细胞稳态。适度激活自噬能有效抑制椎间盘细胞凋亡,延缓细胞外基质(ECM)降解。研究自噬在IDD中的作用机制,针对性地干预其病理生理进程,可为IDD的临床治疗提供新的理念。本文通过查阅近年自噬对IDD作用的相关文献,从IDD及自噬的发生机制、髓核细胞凋亡途径及自噬对髓核细胞凋亡的作用机制等方面展开分析,综述如下。

关键词：椎间盘退行性变自噬细胞凋亡综述文献

在线全文

学校读者我要写书评

暂无评论

偶发分枝杆菌动物模型的建立

诊断病理学杂志 2024年第1期31卷 49-51页

作者：陈丹丹胡顺奇邵良秀江榕刘庆宏中国人民解放军联勤保障部队第九〇〇医院病理科福州350025

偶发分枝杆菌是快速生长分枝杆菌中重要的一种环境机会致病菌,其主要分布在土壤、灰尘、自来水体和饮用水中,感染部位常见于皮肤,骨骼和软组织[1-2]。感染后病人通常表现为脓肿、形成结节、溃疡等。目前国内偶发分杆菌感染性病例报道较少。

关键词：偶发分枝杆菌动物模型组织病理学特殊染色方法熔解曲线法

鸡尾酒抗体D2-40/CD34-CK对淋巴结检出数量不足结直肠癌标本的临床病理评价

在线全文

学校读者我要写书评

暂无评论

临床与实验病理学杂志 2019年第1期35卷 14-18页

作者：刘仙花余英豪齐兴峰吴在增胡顺奇熊喜生向娟郑智勇曲利娟叶显宗联勤保障部队第九○○医院病理科/福建医科大学福总临床医学院/厦门大学附属东方医院福州350025 福建医科大学基础医学院福州350004

目的探讨鸡尾酒抗体D2-40/CD34-CK双重免疫组化染色在淋巴结检出数量不足的结直肠癌(colorectal cancer,CRC)标本脉管侵犯评估中的应用及意义。方法收集133例淋巴结检出数量<12枚的CRC标本,分别行HE染色及鸡尾酒抗体双重免疫组化染色,... 详细信息

目的探讨鸡尾酒抗体D2-40/CD34-CK双重免疫组化染色在淋巴结检出数量不足的结直肠癌(colorectal cancer,CRC)标本脉管侵犯评估中的应用及意义。方法收集133例淋巴结检出数量<12枚的CRC标本,分别行HE染色及鸡尾酒抗体双重免疫组化染色,比较两种方法在脉管侵犯筛查效果中的差异,并分析应用鸡尾酒抗体免疫组化染色证实的脉管侵犯与临床病理特征及患者总生存期(overall survival,OS)的关系。结果 (1)鸡尾酒抗体D2-40/CD34-CK双重免疫组化染色及HE染色对脉管侵犯的检出率分别为42. 9%(57/133)和21. 8%(29/133),差异有显著性(P <0. 001)。(2)鸡尾酒抗体D2-40/CD34-CK双重免疫组化法证实的脉管侵犯与Dukes分期、浸润深度、临床分期、淋巴结转移、肿瘤出芽相关(P <0. 05)。(3)脉管侵犯、侵犯位置深度、程度及脉管侵犯灶数≤2个灶且癌栓细胞数量≥5. 5个与患者OS密切相关(P <0. 05)。结论鸡尾酒抗体D2-40/CD34-CK双重免疫组化染色对脉管侵犯评估优于常规HE染色切片观察,与肿瘤分期、淋巴结转移及出芽情况密切相关,是患者预后的独立影响因素,可作为淋巴结检出数量不足CRC病例的补充检测指标。

关键词：结直肠肿瘤鸡尾酒抗体D2-40/CD34-CK 脉管侵犯预后临床病理