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Coupled funnel control for supersonic tailless aerial vehicle on penetrating counter air

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Chinese Journal of Aeronautics 2024年第7期37卷 458-481页

作者： Yingyang WANG peng ZHANG Jilian GUO Jianbo hu Equipment Management and Unmanned Aerial Vehicle Engineering School Air Force Engineering UniversityXi’an 710051China Aviation Engineering School Air Force Engineering UniversityXi’an 710038China

Supersonic Tailless Aerial Vehicles(STAVs)will become an essential force in Penetrating Counter Air(PCA),but STAVs do not have the traditional horizontal and vertical tails,making pitch and yaw control *** attack angle and the sideslip angle need to be limited to ensure that the engine inlet and the aerodynamic rudder at the rear of the vehicle can work properly,which is the so-called security *** addition,the tracking error of the aerodynamic angle needs to be limited to achieve effective attitude control or high-accuracy tracking of trajectories,which is the so-called performance *** this end,an attitude control method that meets the needs of PCA has been devised,based on constraint definition,coupled constraints handling,and control law ***,mathematical descriptions of the security constraints,performance constraints,and control constraints are ***,two treatment methods,coupled command filter and coupled funnel control are proposed for the aerodynamic angle coupled constraint ***,based on Nonlinear Dynamic Inverse(NDI)design,the coupled funnel controller is designed and validated by simulation for two typical mission scenarios,high-altitude penetration and low-altitude surprise *** proposed control method not only satisfies the security and performance constraints of STAV attitude control but also is highly robust.

关键词： Supersonic tailless aircraft Penetrating counter air Funnel control Attitude control Control allocation

Association between glucose-lowering drugs and circulating insulin antibodies induced by insulin therapy in patients with type 2 diabetes

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World Journal of Diabetes 2024年第7期15卷 1489-1498页

作者： peng Zhang Qing Jiang Bo Ding Reng-Na Yan yun hu Jian-hua Ma Department of Endocrinology Nanjing First HospitalNanjing Medical UniversityNanjing 210000Jiangsu ProvinceChina Department of Endocrinology The Affiliated Wuxi People's Hospital of Nanjing Medical UniversityWuxi Medical CenterWuxi 214000Jiangsu ProvinceChina

BACKGROUND Insulin antibodies(IAs)affect blood glucose control in patients receiving insulin *** To investigate the relationship between different hypoglycemic treatments and IAs in patients with type 2 diabetes mellitus(T2DM).METHODS This cross-sectional,retrospective study included 1863 patients with T2DM who were receiving exogenous insulin *** patients received stable antidiabetic therapy in the last 3 months and IA levels were measured using an iodine-125 *** A total of 1863 patients were *** were 902(48.4%)patients who had positive IAs(IA level>5%),with a mean IA level of 11.06%(10.39%-11.72%).IA levels were positively correlated with high fasting blood glucose(odds ratio=1.069,Phuman insulin only(70.3%),P<*** IA levels in patients using sulfonylureas/glinides(8.3%),metformin(9.6%),and dipeptidyl peptidase-4 inhibitors(8.2%)were all lower than in patients without these drugs(all P<0.05).CONCLUSION Nearly half of patients on insulin therapy have positive IA antibodies,and IA antibody levels are associated with blood glucose *** glargine and a combination of oral glucose-lowering drugs were correlated with lower IA levels.

关键词： Insulin antibodies Insulin therapy Glucose-lowering drugs Glargine Type 2 diabetes

Organic Brønsted Acid-Catalyzed Stereoselective Cationic RAFT Polymerization:The Effect of RAFT Agents

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Chinese Journal of Polymer Science 2024年第6期42卷 711-717页

作者： Zheng-Yi Zhang Zan Yang yun Liao Sai-hu Liao Key Laboratory of Molecule Synthesis and Function Discovery(Fujian Province University) College of ChemistryFuzhou UniversityFuzhou350108China State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China Beijing National Laboratory for Molecular Sciences Beijing100190China

The tacticity of vinyl polymers is a key factor affecting the properties of ***,organic Brønsted acids have been demonstrated as effective catalysts for the development of highly stereoselective cationic reversible addition-fragmentation chain transfer(RAFT)polymerizations of vinyl ethers,in which the use of RAFT agents could allow the control the molecular weight and tacticity of polymer products ***,the effect of RAFT agents on the tacticity-regulation remains elusive and lacks of *** this study,we synthesized four types of RAFT agents and evaluated their influence in the stereoselective cationic polymerization of isobutyl vinyl ether in the presence of PADI as a Brønsted acid catalyst,which unveils that the Z group of RAFT agents could not only affect the polydispersity of the products,but also exert a profound effect on the *** extensive screening of the RAFT agents,high stereoregularity(isotacticity,90%m)was obtained when using dithiocarbonate ester-type RAFT agents with a benzyloxy Z group.

关键词： Bronsted acid catalysis Stereoselective cationic polymerization RAFT polymerization Chain transfer agents Tacticity

Enhanced cycling stability and rate performance of Co-doped and La_(2)O_(3)-coated LiNi_(0.9)Mn_(0.1)O_(2) toward power battery

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Rare Metals 2024年第2期43卷 658-670页

作者： Jia-Qi peng Yuan-Yuan Wei Dong-Ming Liu yun Li Bin hu Bin huang Jian-Wen Yang Shun-hua Xiao Ren-Heng Wang Guangxi Key Laboratory of Electrochemical and Magneto-Chemical Functional Materials College of Chemistry and BioengineeringGuilin University of TechnologyGuilin541004China Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen518060China

Ultra-high nickel layered oxide cathode material with high energy density is the most promising material to improve the electrochemical performance of lithium-ion batteries(LIBs).However,the poor structural stability and severe surface/interface side reactions of the material lead to poor rate performance and cyclic stability,which limits its application in *** this paper,the dual-modification strategy of Co doping and La_(2)O_(3) coating is used to meet the above *** doping can effectively widen layer spacing and reduce Li^(+)/Ni^(2+) mixing,and La_(2)O_(3) coating can effectively eliminate the residual alkali on the surface of active material,inhibit the thickening of cathode electrolyte interphase(CEI)film and reduce surface/interface side ***,the modified material(NM90-CL)with excellent electrochemical properties is achieved through the synergistic enhancement of Co doping and La_(2)O_(3) *** capacity retention rate can reach 77.9%after 200 cycles at 1.0℃ and 75.7%after 200 cycles at 5.0℃.Its reversible capacity can up to 153.5 mAh·g^(–1) at 10.0℃.This dual-modification strategy will provide theoretical guidance and technical support for the synthesis of other high-performance electrode materials.

关键词： High nickel cathode material Co doping La_(2)O_(3) coating Electrochemical performance Electrochemical mechanism

Path Tracking Controller Design of Automated Parking Systems via NMPC with an Instructible Solution

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Chinese Journal of Mechanical Engineering 2024年第3期37卷 353-367页

作者： Liang Chen Zhaobo Qin Manjiang hu Yougang Bian Xiaoyan peng State Key Laboratory of Advanced Design and Manufacturing Technology for Vehicle College of Mechanical and Vehicle EngineeringHunan UniversityChangsha 410082China Wuxi Intelligent Control Research Institute of hunan University Wuxi 214115China

Parking difficulties have become a social issue that people have to *** parking system is practicable for quick par operations without a driver which can also greatly reduces the probability of parking *** paper proposes a Lyapunov-based nonlinear model predictive controller embedding an instructable solution which is generated by the modified rear-wheel feedback method(RF-LNMPC)in order to improve the overall path tracking accuracy in parking ***,A discrete-time RF-LNMPC considering the position and attitude of the parking vehicle is proposed to increase the success rate of automated parking ***,the RF-LNMPC problem with a multi-objective cost function is solved by the Interior-Point Optimization,of which the iterative initial values are described as the instructable solutions calculated by combining modified rear-wheel feedback to improve the performance of local optimal ***,the details on the computation of the terminal constraint and terminal cost for the linear time-varying case is *** closed-loop stability is verified via Lyapunov techniques by considering the terminal constraint and terminal cost ***,the proposed RF-LNMPC is implemented on a selfdriving Lincoln MKZ platform and the experiment results have shown improved performance in parallel and vertical parking *** Monte Carlo analysis also demonstrates good stability and repeatability of the proposed method which can be applied in practical use in the near future.

关键词： Automated parking Path tracking controller Nonlinear model predictive control Monte Carlo analysis

Advances and challenges in artificial intelligence text generation

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Frontiers of Information Technology & Electronic Engineering 2024年第1期25卷 64-83页

作者： Bing LI peng YANG Yuankang SUN Zhongjian hu Meng YI School of Computer Science and Engineering Southeast UniversityNanjing 210000China Key Laboratory of Computer Network and Information Integration Ministry of EducationSoutheast UniversityNanjing 210000China

Text generation is an essential research area in artificial intelligence(AI)technology and natural language processing and provides key technical support for the rapid development of AI-generated content(AIGC).It is based on technologies such as natural language processing,machine learning,and deep learning,which enable learning language rules through training models to automatically generate text that meets grammatical and semantic *** this paper,we sort and systematically summarize the main research progress in text generation and review recent text generation papers,focusing on presenting a detailed understanding of the technical *** addition,several typical text generation application systems are ***,we address some challenges and future directions in AI text *** conclude that improving the quality,quantity,interactivity,and adaptability of generated text can help fundamentally advance AI text generation development.

关键词： AI text generation Natural language processing Machine learning Deep learning

Prenatal amoxicillin exposure induces developmental toxicity in fetal mice and its characteristics

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Journal of Environmental Sciences 2024年第3期137卷 287-301页

作者： Yongguo Dai Yu peng Wen hu Yi Liu hui Wang Department of Pharmacology Wuhan University School of Basic Medical SciencesWuhan 430071China Department of Pharmacy Zhongnan Hospital of Wuhan UniversityWuhan 430071China hubei Provincial Key Laboratory of Developmentally Originated Disease Wuhan 430071China

Amoxicillin,a widely used antibiotic in human and veterinary pharmaceuticals,is now considered as an“emerging contaminant”because it exists widespreadly in the environment and brings a series of adverse ***,systematic studies about the developmental toxicity of amoxicillin are still *** explored the potential effects of amoxicillin exposure on pregnancy outcomes,maternal/fetal serum phenotypes,and fetal multiple organ development in mice,at different doses(75,150,300 mg/(kg·day))during late-pregnancy,or at a dose of 300 mg/(kg·day)during different stages(mid-/latepregnancy)and courses(single-/multi-course).Results showed that prenatal amoxicillin exposure(PAmE)had no significant infuence on the body weights of dams,but it could inhibit the physical development and reduce the survival rate of fetuses,especially during the ***,PAmE altered multiple maternal/fetal serum phenotypes,especially in *** multi-organ function results showed that PAmE inhibited testicular/adrenal steroid synthesis,long bone/cartilage and hippocampal development,and enhanced ovarian steroid synthesis and hepatic glycogenesis/lipogenesis,and the order of severity might be gonad(testis,ovary)>liver>*** analysis found that PAmE-induced multiorgan developmental and functional alterations had differences in stages,courses and fetal gender,and the most obvious changes might be in high-dose,late-pregnancy and multicourse,but there was no typical rule of a dose-response *** conclusion,this study confirmed that PAmE could cause abnormal development and multi-organ function alterations,which deepens our understanding of the risk of PAmE and provides an experimental basis for further exploration of the long-term harm.

关键词： Amoxicillin Prenatal exposure Fetal development Organ function Developmental toxicity

Joined AZ31B Magnesium Alloys with Ag Interlayer by Ultrasonic-Induced Transient Liquid Phase Bonding in Air

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Acta Metallurgica Sinica(English Letters) 2024年第7期37卷 1177-1185页

作者： Qian Wang peng Yu Haoran Lin Chongzhi Guo Xiaoqiang hu Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou341119China School of Rare Earths University of Science and Technology of ChinaHefei230026China Shenyang 7D New Materials Equipment Co.LTD. Shenyang110076China Shenyang National Laboratory of Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang110016China

AZ31B magnesium alloys are commonly used in lightweight structures of automobile and aerospace *** this work,the ultrasonic-induced transient liquid phase bonding technique is deployed to joint AZ31B magnesium alloys at 490℃ with Ag interlayer in the *** effect of ultrasonic vibration on microstructure and mechanical properties of welding seam is *** vibration duration increases,the width of the welding seam increases firstly and then *** the ultrasound vibration sustained for one second,the eutectic reaction occurred in the contacting interface between Ag interlayer and the base metal AZ31B,resulting in formation of liquid phase and metallurgical *** the ultrasound vibration sustained for seven second,the width of the welding seam increased to a maximum of about 303.1μm and the average shear bond strength of the welding joint attained the peak value of about 66.87 *** the ultrasound vibration sustained over seven seconds,the liquid phase is gradually squeezed out and the width of the welding seam decreases.α-Mg and AgMg_(3) can be observed in the welding *** analysis shows thatα-Mg has a certain strengthening *** whole process of appearance,growth and integration ofα-Mg is analyzed.

关键词： Ultrasonic bonding Magnesium alloy Silver Microstructure Intermetallic compound

Role of deubiquitinase JOSD2 in the pathogenesis of esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2024年第6期30卷 565-578页

作者： Wen-peng Wang Dan Shi Duo yun Jun hu Jie-Fu Wang Jia Liu Yan-peng Yang Ming-Rui Li Jun-FengWang Da-Lu Kong Department of Colorectal Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin’s Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin 300060China Department of Gastrointestinal Surgery Tianjin Nan Kai HospitalTianjin Medical UniversityTianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM RepairInstitute of Integrative Medicine for Acute Abdominal DiseasesTianjin 300100China Department of Oncology The First Hospital of HohhotHohhot 010000Inner Mongolia Autonomous RegionChina Department of Endocrinology Dazhou Central HospitalDazhou 635000Sichuan ProvinceChina

BACKGROUND Esophageal squamous cell carcinoma(ESCC)is a deadly malignancy with limited treatment ***(DUBs)have been confirmed to play a crucial role in the development of malignant ***2 is a DUB involved in con-trolling protein deubiquitination and influencing critical cellular processes in *** To investigate the impact of JOSD2 on the progression of *** Bioinformatic analyses were employed to explore the expression,prognosis,and enriched pathways associated with JOSD2 in *** transduction was utilized to manipulate JOSD2 expression in ESCC cell lines(KYSE30 and RESULTS )Preliminary research indicated that JOSD2 was highly expressed in ESCC tissues,which was associated with poor *** analysis demonstrated that JOSD2 was upregulated in ESCC cell lines compared to normal esophageal ***2 knockdown inhibited ESCC cell activity,including proliferation and colony-forming ***,JOSD2 knockdown decreased the drug resistance and migration of ESCC cells,while JOSD2 overexpression enhanced these *** vivo xenograft assays further confirmed that JOSD2 promoted tumor proliferation and drug resistance in ***,JOSD2 appears to activate the MAPK/ERK and PI3K/AKT signaling *** spectrometry was used to identify crucial substrate proteins that interact with JOSD2,which identified the four primary proteins that bind to JOSD2,namely USP47,IGKV2D-29,HSP90AB1,and *** JOSD2 plays a crucial role in enhancing the proliferation,migration,and drug resistance of ESCC,suggesting that JOSD2 is a potential therapeutic target in ESCC.

关键词： Esophageal squamous cell carcinoma JOSD2 Ubiquitination Biomarker Targeted therapy Drug resistance