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Na_(2)O/Li_(2)O Ratio Dependency on the Thermal,Mechanical,Dielectric Properties and Chemical Stabilities of Li_(2)O-Al_(2)O_(3)-SiO_(2) Glass

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Journal of Wuhan University of Technology(Materials Science) 2022年第6期37卷 1129-1136页

作者： CHEN Lina XIE Jun WANG Mingzhong CAO Shiyi CUI Xiuzhen LIANG Xinhui ZHANG Jihong HAN Jianjun hu kaiwen State Key Laboratory of Silicate Materials for Architectures Wuhan University of TechnologyWuhan 430070China Shenzhen Research Institute of Wuhan University of Technology Shenzhen 518000China Xianning Nanbo Photoelectric Glass Co.Ltd. Xianning 437100China International School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China

Li_(2)O-Al_(2)O_(3)-SiO_(2) based glasses were investigated as potential protection glass for electronic devices due to their excellent mechanical properties,such as high hardness,toughness,and scratch *** this paper,Li_(2)O-Na_(2)O-Al_(2)O_(3)-SiO_(2) glass with different Li_(2)O/Na_(2)O ratio components were prepared by meltquenching method,and the effects of Na_(2)O/Li_(2)O ratio on the glass densities,structure,thermal,mechanical properties,and chemical stabilities were *** experimental results indicate that the glass transition temperature increases with the increases in Na_(2)O/Li_(2)O ratios,due to larger ion *** the thermal expansion coefficient slightly decreases from 11.4×10^(-6) to 11.09×10^(-6)/℃.The elastic modulus increases from 57 to 72 *** bending strength reaches maximum 80.90 MPa when the Na_(2)O/Li_(2)O ratio is 1.7,then decreases as the ratio further *** addition,the Vicker’s hardness gets to 7.37 GPa with largest Na_(2)O/Li_(2)O ***,the dielectric loss and dielectric constant increases as the ratio *** Raman structure analysis shows the Q4[Si-O-Si]decreases as Na_(2)O/Li_(2)O ratio increases,which is responsible for the characteristic properties ***,the glass shows lowest mass loss in 10vol%HF solutions when the ratio is 1.4,while 1.7 in 5wt%NaOH solution.

关键词： glass composition dielectric constant coefficient of thermal expansion elastic modulus

Theory and practice of cancer“Green Therapy”

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Journal of Traditional Chinese Medical Sciences 2016年第4期3卷 201-205页

作者： kaiwen hu Tian Zhou Dongfang Hospital Beijing University of Chinese MedicineBeijing 100078China

Under the guidance of the theory of traditional Chinese medicine(TCM),the“Green Therapy”for tumors aims to“control”the condition,i.e.“When lethal treatments were adopted,they should be discontinued when six-tenths of the disease is eliminated;When treatments with moderate toxicity were chosen,they should be stopped when seven-tenths of the disease is eliminated;When treatments with mild toxicity were using,they should be discontinued when eight-tenths of the disease is eliminated;Even if using non-toxic treatments,they should be terminated when nine-tenths of the disease is wiped out..If the efficacy is below our expectation,we could repeat the treatments;But if go beyond the extent,healthy qi will be damaged and it will not be beneficial or even do harm to the repair capability of the body”,which underlines the end point of treatment,or“stop interventions when half of the disorder is gone”.Based on the Green Therapy theory,minimally invasive surgeries,TCM external treatments,natural medications and the biological target therapies are main approaches in our clinical cancer *** differs from the modern treatment *** Green Therapy for cancers treats“patient’s quality of life”as our *** therapy system is particularly suitable for cancer patients who are aged and disqualified for or failed from classic anti-cancer *** is a new trend of anti-cancer strategy characterized by effectiveness,minimally invasion,quick recovery,easy toleration and great sustainability.

关键词： Green Therapy Malignant tumor Cancer Strategy Traditional Chinese medicine

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管道中非定常流动的计算分析

农业机械学报 1999年第5期30卷 28-31页

作者：胡开文合肥经济技术学院机电工程系

对管道中非定常流动进行了研究，导出了流体在管道中流动时，实用的特征线法的计算方法和公式。该方法是从Ｎａｖｉｅｒ－Ｓｔｏｋｅｓ方程和连续性方程出发，结合流体实际流态状况及摩擦损失函数等，将难以求解的流体偏微分方程组转换... 详细信息

对管道中非定常流动进行了研究，导出了流体在管道中流动时，实用的特征线法的计算方法和公式。该方法是从Ｎａｖｉｅｒ－Ｓｔｏｋｅｓ方程和连续性方程出发，结合流体实际流态状况及摩擦损失函数等，将难以求解的流体偏微分方程组转换为便于工程数值计算的等价差分方程组，从而解决了液压管道中液体非定常流动的计算问题。它能很好地满足实际工程计算需要。

关键词：非定常流动特征线法数值计算管道液体管道

Inhibition of growth and metastasis of triple-negative breast cancer targeted by Traditional Chinese Medicine Tubeimu in orthotopic mice models

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Chinese Journal of Cancer Research 2018年第1期30卷 112-121页

作者： Jingxiao Wang Xinjie Yang Haibo Han Limin Wang Weiqian Bao Shanshan Wang Robert M.Hoffman Meng Yang hui Qi Chao An kaiwen hu Beijing University of Chinese Medicine Beijing 100029 China Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Biobank Peking University Cancer Hospital & Institute Beijing 100142 China Anti Cancer Inc. San DiegoCA 92111 USA Department of Surgery University of California San Diego CA 92103-8220 USA Anti Cancer Biotech Co Ltd. Beijing102200 China Department of Oneology Dongfang Hospital Beijing University of Chinese Medicine Beijing 100078 China

Objective： Triple-negative breast cancer（TNBC） is highly invasive and metastatic, which is in urgent need of transformative therapeutics. Tubeimu（TBM）, the rhizome of Bolbostemma paniculatum（Maxim.） Franquet, is one of the Chinese medicinal herbs used for breast diseases since the ancient times. The present study evaluated the efficacy, especially the anti-metastatic effects of the dichloromethane extract of Tubeimu（ETBM） on TNBC orthotopic mouse models and cell ***： We applied real-time imaging on florescent orthotopic TNBC mice model and tested cell migration and invasion abilities with MDA-MB-231 cell line. Digital gene expression sequencing was performed and Kyoto Encyclopedia of Genes and Genomes（KEGG） analysis applied to explore the pathways influenced by ***, quantitative real-time polymerase chain reactions（q RT-PCR） and Western blot were delivered to confirm the gene expression ***： ETBM exhibited noticeable control on tumor metastasis and growth of TNBC tumors with no obvious toxicity. In compliance with this, it also showed inhibition of cell migration and invasion in vitro. Its impact on the changed biological behavior in TNBC may be a result of decreased expression of integrin β1（ITGβ1）, integrin β8（ITGβ8） and Rho GTPase activating protein 5（ARHGAP5）, which disabled the focal adhesion pathway and caused change in cell ***： This study reveals that ETBM has anti-metastatic effects on MDA-MB-231-GFP tumor and may lead to a new therapeutic agent for the integrative treatment of highly invasive TNBC.

关键词： Tubeimu triple negative breast cancer(TNBC) orthotopic mouse models Traditional Chinese Medicine(TCM) integrins Rho GTPase activating protein 5

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振动输送机隔振的研究

农业机械学报 1999年第4期30卷 43-46页

作者：胡开文合肥经济技术学院机电工程系

通过研究振动输送机的多自由度振动系统，建立了振动输送机的振动模型，并给出了满足主动隔振的条件，从而为振机结构和隔振设计提供了理论依据。

关键词：多自由度系统振动振动输送机隔振

Discrimination of TCM constitutions by biochemical and routine urine indexes

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Journal of Traditional Chinese Medical Sciences 2022年第2期9卷 153-159页

作者： Xiaoling Liu Pengfei Zhao Jianhua Zhen Shen Zhang Hesong Wang Yuxiu Sun Wei Wang Tingjian Wang kaiwen hu Guangrui huang School of Life Sciences Beijing University of Chinese MedicineBeijing102488China Dongfang Hospital Beijing University of Chinese MedicineBeijing100078China Beijing Research Institute of Chinese Medicine Beijing University of Chinese MedicineBeijing100029China Department of Cancer Biology Dana-Farber Cancer InstituteBostonMA02215USA

Objective:To investigate whether the specific traditional Chinese medicine(TCM)constitution of individuals can be defined by certain biological indexes instead of answering the questionnaire,and to explore the possibility of discriminating nine TCM constitutions from each other simultaneously using biological ***:Blood and urine samples from 152 individuals with nine TCM constitutions were collected,and the related biological indexes were analyzed combining ANOVA,multiple comparison,discriminant analysis,and support vector ***:We found that 4 out of 24 blood routine indexes,7 out of 10 urine routine indexes,and 12 out of 32 biochemical indexes showed differences among the ***-sensitivity C-reactive protein,apolipoprotein A1,and alkaline phosphatase were potential candidates for screening out individuals with unbalanced *** uric acid,high-density lipoprotein,apolipoprotein A1,creatine kinase,total protein,aspartate aminotransferase,total bile acid,dehydrogenase,sodium,and calcium levels had the potential to directly distinguish the nine TCM constitutions from each *** these indexes,the highest ratio of discriminant analysis between two constitutions was 95.5%,while the lowest was 66.1%.Conclusion:Our results suggest that some biochemical and urine indexes are related to various TCM constitutions,and thus they have the potential to be used for TCM constitution classification.

关键词： Traditional Chinese medicine Constitution classification Balance constitution Unbalanced constitutions Biochemical indexes Routine urine indexes Linear discriminant analysis

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齿轮泵工作原理的探讨

农业机械学报 2000年第2期31卷 67-70页

作者：胡开文徐金榜合肥经济技术学院机电工程系合肥市230052 安徽省烟草公司合肥市230052

目前 ,有关教材及手册对齿轮泵的工作原理几乎一致认为 :当泵的齿轮旋转时 ,随着啮合点变化 ,吸油腔工作容积增大 ,形成部分真空 ,产生吸油作用 ;在压油腔中 ,由于轮齿逐渐进入啮合 ,其工作容积减小 ,向压力管路产生压油作用。事实上 ,... 详细信息

目前 ,有关教材及手册对齿轮泵的工作原理几乎一致认为 :当泵的齿轮旋转时 ,随着啮合点变化 ,吸油腔工作容积增大 ,形成部分真空 ,产生吸油作用 ;在压油腔中 ,由于轮齿逐渐进入啮合 ,其工作容积减小 ,向压力管路产生压油作用。事实上 ,这种对齿轮泵工作原理所做的解释是不全面的。笔者从齿轮泵流量和吸油区产生真空机理两方面对这一问题的实质进行了探讨。

关键词：齿轮泵工作原理流量吸油区真空

改革开放初期广州酒店建筑遗产的历史见证及历史借鉴价值

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现代城市研究 2022年第9期37卷 112-117页

作者：胡凯雯华南理工大学建筑学院、亚热带建筑科学国家重点实验室

改革开放初期,广州修建了一批我国传统岭南文化与西方现代文化于一体的特色建筑。它们是我国20世纪建筑遗产的重要组成部分,具有十分重要的价值。文章主要以广州改革开放初期兴建的酒店建筑为例,深入分析其独特的历史见证价值与历史借... 详细信息

改革开放初期,广州修建了一批我国传统岭南文化与西方现代文化于一体的特色建筑。它们是我国20世纪建筑遗产的重要组成部分,具有十分重要的价值。文章主要以广州改革开放初期兴建的酒店建筑为例,深入分析其独特的历史见证价值与历史借鉴价值,旨在阐明我国特殊时段、特殊地域兴建的特色建筑之特殊本质,更透彻地阐释保护好现代建筑遗产的重要意义,进而为新时代深入推进我国现代建筑遗产保护事业高质量发展、现代化酒店建筑设计的多元化和国际化提供借鉴。

关键词：改革开放初期广州酒店建筑遗产历史见证价值历史借鉴价值

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胡凯文教授运用中医思维临床辨治肿瘤经验

吉林中医药 2021年第6期41卷 705-708页

作者：夏清克晓燕胡凯文北京中医药大学北京100029 北京中医药大学东方医院北京100078

胡凯文教授认为肿瘤同时具有阴阳两种属性,临床辨证从患者整体出发,治疗上以脾胃为重,用药上注重平调阴阳、攻补兼施,调理气机、祛痰化浊,补气养血,脾肾同补,最终达到延缓肿瘤进展,提高患者生存时间和生活质量的疗效。

关键词：肿瘤胡凯文阴阳气机脾胃