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STUDY OF COLLAGEN-POLYVINYL ALCOHOL COMPOSITES

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Chinese Journal of Biomedical Engineering(English Edition) 1993年第3期2卷 115-115页

作者： Qiqing Zhang~1 Lei Ren~1 Ping Yuan~2 jianfang hu~21 Institute of Biomedical Engineering,Chinese Academy of Medical Sciences,P.O.Box.25(204).Tianjin 300192,China2 Centra Nationalities Institute,Beijing,China

Collagen is the major acellcar of connective tissue protein in animals,accountingfor about 25% of the total body protein of *** essential feature of thistype of biomaterial is that it degrades in biologic environments,eventually disap-pears,and leaves no permanent foreign residue.A very practical aspect of the use ofcollagen is its ease of preparation and its widespread occurrence in ***,col-lagen has been employed as a biomaterial in almost every physical *** exam-ple,collagen fibres can be used as a substrate for nerve regeneration,tendon

关键词： biomaterial tendon biologic Collagen ligament collagen permanent fibres regeneration connective

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饲料害虫的发生规律及防治

粮食储藏 2000年第1期29卷 20-26页

作者：易平炎李会新魏木山边滔杨长举杨志慧华红霞胡建芳湖北省天门市粮食局 431700 华中农业大学植保系 430070

经系统普查，在饲料中发现27种害虫及其天敌。鞘翅目害虫占63．9％，原料仓中优势对为赤拟谷盗、玉米象、谷蠹、亚扁粉盗。生产车间优势种为黑菌虫、赤拟谷盗、玉米象。成品饲料中的优势种为赤拟谷盗、谷蠹、长角扁谷盗、亚扁粉盗。主... 详细信息

经系统普查，在饲料中发现27种害虫及其天敌。鞘翅目害虫占63．9％，原料仓中优势对为赤拟谷盗、玉米象、谷蠹、亚扁粉盗。生产车间优势种为黑菌虫、赤拟谷盗、玉米象。成品饲料中的优势种为赤拟谷盗、谷蠹、长角扁谷盗、亚扁粉盗。主要害虫高峰期在6～9月。主要优势种的数量随季节变动表现出不连续特点。成品词料初期害虫竞争性大小为谷蠹＞玉米象；后期害虫竞争性大小为赤拟谷盗＞锯谷盗＞锈赤扁谷盗。饲料抗虫性随饲料颗粒大小而异，颗粒越小，抗虫性越弱。塑料最密封261天的饲料中害虫比未封装的少59．7％。抗虫袋包装饲料可防虫2个月。

关键词：饲料害虫发生规律种群防治技术贮藏

局部针刺合药棒冰刺激治疗对卒中后吞咽障碍患者脑血流量的影响

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针灸临床杂志 2018年第12期34卷 10-13页

作者：胡建芳余志辉毕小丽陈朝俊杨沛群樊哲江刘媛刘天福广州市中西医结合医院广东广州510800

目的:观察局部针刺合药棒冰刺激治疗对卒中后吞咽障碍患者吞咽功能、血流动力学及经颅多普勒的影响。方法:80例卒中后吞咽障碍患者随机分为治疗组和对照组,各40例,所有患者均给予综合基础治疗,治疗组在上述治疗基础上加用局部针刺及药... 详细信息

目的:观察局部针刺合药棒冰刺激治疗对卒中后吞咽障碍患者吞咽功能、血流动力学及经颅多普勒的影响。方法:80例卒中后吞咽障碍患者随机分为治疗组和对照组,各40例,所有患者均给予综合基础治疗,治疗组在上述治疗基础上加用局部针刺及药棒冰刺激治疗,共4周;检测两组患者治疗前后洼田氏饮水试验、SSA评分、血液流变学及经颅多普勒等指标的变化,比较两组差异。结果:与治疗前相比,两组患者洼田饮水试验均明显改善、SSA评分下降(P 0. 05)。结论:局部针刺合药棒冰刺激治疗能改善卒中后吞咽障碍患者的吞咽功能,其作用机制可能与通过改善患者血液循环、增加脑部供血从而促进神经功能的修复有关。

关键词：脑卒中吞咽障碍针刺冰刺激脑血流量

Manipulating exciton confinement for stable and efficient flexible quantum dot light-emitting diodes

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Photonics Research 2024年第9期12卷 1927-1936页

作者： XIAOYUN hu jianfang YANG YUFEI TU ZHEN SU FEI Zhu QINGQING GUAN ZHIWEI MA Key Laboratory of Oil and Gas Fine Chemicals Ministry of EducationCollege of Chemical EngineeringXinjiang UniversityUrumqi 830017China School of Telecommunications and Intelligent Manufacturing Sias UniversityXinzheng 451150China CAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-LabSuzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China

Flexible quantum dot light-emitting diodes(QLEDs)show great promise for the next generation of flexible,wearable,and artificial intelligence display ***,the performance of flexible QLEDs still lags behind that of rigid substrate devices,hindering their commercialization for display *** we report the superior performance of flexible QLEDs based on efficient red ZnCdSe/ZnS/ZnSe QDs(A-QDs)with antitype-I *** reveal that using ZnS as an intermediate shell can effectively confine the exciton wavefunction to the inner core,reducing the surface sensitivity of the QDs and maintaining its excellent emission *** flexible QLEDs exhibit a peak external quantum efficiency of 23.0%and a long lifetime of 63,050 h,*** anti-type-I nanostructure of A-QDs in the device simultaneously suppresses defectinduced nonradiative recombination and balances carrier injection,achieving the most excellent performance of flexible QLEDs ever *** study provides new insights into achieving superior performance in flexible QD-based electroluminescent devices.

关键词： diodes quantum light

Differential structure of Ordovician karst zone and hydrocarbon enrichment in paleogeomorphic units in Tahe area,Tarim Basin,NW China

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Petroleum Exploration and Development 2021年第5期48卷 1113-1125页

作者： ZHANG San JIN Qjang hu Mingyi HAN Qichao SUN jianfang CHENG Fuqi ZHANG Xudong School of Geosciences Yangtze UniversityWuhan 430100China School of Geosciences China University of PetroleumQingdao 266580China Gudao Oil Production Plant Shengli Oilfield Company of SinopecDongying 257231China Exploration and Development Institute SinopecBeijing 100083China

Based on a large number of drilling,logging,seismic and production data,the differential structures of karst zone and hydrocarbon distribution in different paleogeomorphic units of the Tahe area,Tarim Basin,are discussed by analyzing the karst drainages and flowing *** karst paleogeomorphy of Ordovician in Tahe area is composed of watershed,karst valley and karst *** watershed has epikarst zone of 57.8 m thick on average and vadose karst zone of 115.2 m thick on average with dense faults,fractures and medium-small fracture-caves,and 76.5%of wells in this area have cumulative production of more than 5×10^(4) t per *** karst valleys have epikarst zone,vadose karst zone and runoff karst zone,with an average thickness of 14.6,26.4 and 132.6 m *** the runoff karst zone,the caves of subsurface river are mostly filled by fine sediment,with a filling rate up to 86.8%,and 84.9%of wells in this area have cumulative production of less than 2×10^(4) t per *** karst basin has no karst zone,but only fault-karst reservoirs in local fault zones,which are up to 600 m thick and closely developed within 1 km around *** karst landforms have different water flowing pattern,forming different karst zone structures and resulting in differential distribution of oil and *** watershed has been on the direction of oil and gas migration,so medium-small sized connected fracture-caves in this area have high filling degree of oil and gas,and most wells in this area have high *** caves in subsurface river are filled due to strong sedimentation and transportation of the river,so the subsurface river sediment has low hydrocarbon abundance and more low production oil *** faults linking source rock are not only the water channels but also the oil-gas migration pathways,where the karst fractures and caves provide huge reservoir space for oil and gas accumulation.

关键词： paleokarst karst drainage watershed fracture-cave structure oil and gas distribution Tahe Oilfield Ordovician Tarim Basin

Biogeochemistry of sedimentary organic matter in the Yongjiang River estuary in the southern part of Hangzhou Bay,China,since the Late Pleistocene

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Journal of Oceanology and Limnology 2024年第3期42卷 772-786页

作者： Dongqin huANG Xiaolong LI Zilong LI Pei Sun LOH Jianxiong hu jianfang CHEN Yuan-Pin CHANG Chin-Wen YANG Qin GAO Institute of Marine Geology and Resources Ocean CollegeZhejiang UniversityZhoushan 316021China Ministry of Water Resources of the People’s Republic of China Beijing 100054China Key Laboratory of Marine Ecosystem Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Department of Oceanography Sun Yat-sen UniversityKaohsiung 80424China

A sediment core(YJK19-02)collected from the southern outlet of Hangzhou Bay near the Yongjiang River estuary in East China was analyzed for grain size,lignin,bulk elemental composition,stable carbon isotope,and rare earth elements(REEs)to determine the sources and diagenesis of sedimentary organic matter(OM)of the estuary and adjacent areas since the Late Pleistocene.δ^(13)C values(-24.80‰–-23.60‰),total organic carbon/total nitrogen(TOC/TN)molar ratios(8.00–12.14),and light rare earth element/heavy rare earth element ratios(LREE/HREE=8.34–8.91)revealed the predominance of terrestrial sources of OM,mainly from the Changjiang(Yangtze)*** lignin parameters of syringyl/vanillyl(S/V=0.20–0.73)and cinnamyl/vanillyl(C/V=0.03–0.19)ratios indicate the predominance of nonwoody angiosperms,and the vanillic acid/vanillin ratios[(Ad/Al)_(V)=0.32–1.57]indicate medium to high degrees of lignin *** increasing trend ofΛ(total lignin in mg/100-mg OC)values from ca.14500 a BP to ca.11000 a BP reflected the increase in temperature during the Late ***,a time lag effect of temperature on vegetation abundance was also *** relatively higher and stableΛvalues correspond to the higher temperature during the mid-Holocene from ca.8500 a BP to ca.4500 a BP.Λvalues decreased from ca.4000 a BP to the present,corresponding to historical temperature fluctuations during this *** results show that the vegetation abundance in the Yongjiang River Basin since the Late Pleistocene was related to the temperature fluctuation duo to climate change.

关键词： Yongjiang River estuary sedimentary organic matter lignin environmental change Late Pleistocene

Tumor-specific memory CD8^(+)T cells are strictly resident in draining lymph nodes during tumorigenesis

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Cellular & Molecular Immunology 2023年第4期20卷 423-426页

作者： Qiao Liu Ling Ran Zhengliang Yue Xingxing Su Lisha Wang Shuqiong Wen Shun Lei Xiaofan Yang Yan Zhang Jianjun hu jianfang Tang Zhirong Li Li hu Bo Zhu Lifan Xu Lilin Ye Qizhao huang Shanghai Public Health Clinical Center Fudan UniversityShanghaiChina Institute of Cancer Xinqiao HospitalThird Military Medical UniversityChongqingChina Institute of Immunology Third Military Medical UniversityChongqingChina Stomatological Hospital of Chongqing Medical University ChongqingChina Provincial Key Laboratory of Immune Regulation and Immunotherapy School of Laboratory Medicine and BiotechnologySouthern Medical UniversityGuangzhouChina College of Veterinary Medicine Qingdao Agricultural UniversityShandongChina Institute of Immunological Innovation and Translation Chongqing Medical UniversityChongqingChina.8 These authors

The functional exhaustion of CD8^(+)T cells represents a fundamental hallmark of chronic viral infection and cancer and,in both scenarios,is driven by prolonged exposure to persistent cognate antigens in the context of an immunoinhibitory *** CD8^(+)T cells upregulate the expression of a wide diversity of coinhibitory immunoreceptors(also referred to as immune checkpoint receptors),such as PD-1,Tim-3,LAG-3,and ***,exhausted CD8^(+)T cells lose their potential to differentiate into functional memory cells and are characterized by hierarchical loss of effector function,leading to compromised tumor control and viral eradication[1,2].

关键词： drain strictly specific

The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity

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Signal Transduction and Targeted Therapy 2021年第4期6卷 1292-1301页

作者： Leiqiong Gao Jing Zhou Sen Yang Lisha Wang Xiangyu Chen Yang Yang Ren Li Zhiwei Pan Jing Zhao Zhirong Li Qizhao huang jianfang Tang Li hu Pinghuang Liu Guozhong Zhang Yaokai Chen Lilin Ye Institute of Immunology Third Military Medical UniversityChongqingChina Chongqing Public Health Medical Center ChongqingChina State Key Laboratory of Veterinary Biotechnology Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbinHeilongjiangChina College of Veterinary Medicine Northeast Agricultural UniversityHarbinHeilongjiangChina Key Laboratory of Animal Epidemiology of the Ministry of Agriculture College of Veterinary MedicineChina Agricultural UniversityBeijingChina Cancer Center The General Hospital of Western Theater CommandChengduSichuanChina Comparative Immunology Research Center College of Veterinary MedicineChina Agricultural UniversityBeijingChina

The adaptive immunity that protects patients from coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is not well *** particular,the asymptomatic patients have been found to induce weak and transient SARS-CoV-2 antibody responses,but the underlying mechanisms remain unknown;meanwhile,the protective immunity that guide the recovery of these asymptomatic patients is ***,we characterized SARS-CoV-2-specific B-cell and T-cell responses in 10 asymptomatic patients and 64 patients with other disease severity(mild,n=10,moderate,n=32,severe,n=12)and found that asymptomatic or mild symptomatic patients failed to mount virus-specific germinal center(GC)B cell responses that result in robust and prolonged humoral immunity,assessed by GC response indicators including follicular helper T(TFH)cell and memory B cell responses as well as serum CXCL13 ***,these patients mounted potent virus-specific TH1 and CD8+T cell *** sharp contrast,patients of moderate or severe disease induced vigorous virus-specific GC B cell responses and associated TFH responses;however,the virus-specific TH1 and CD8+T cells were minimally induced in these *** results,therefore,uncovered the protective immunity in asymptomatic patients and also revealed the strikingly dichotomous and incomplete humoral and cellular immune responses in COVID-19 patients with different disease severity,providing important insights into rational design of effective COVID-19 vaccines.

关键词： immunity patients severity

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长方体单腔室空腔环境内爆炸效应的实验研究

爆炸与冲击 2016年第3期36卷 340-346页

作者：胡洋朱建芳朱锴华北科技学院安全工程学院矿井灾害防治重点实验室北京101601

为了获得在典型空腔内发生爆炸后,结构壁面上爆炸载荷的分布规律和空腔结构的破坏形式,以国防工事和人防工事的等级设计规范为依据,设计了长方体单腔室空腔模型,并对该模型进行了药量逐渐递增直至可使结构破坏的内爆炸实验。用压力传感... 详细信息

为了获得在典型空腔内发生爆炸后,结构壁面上爆炸载荷的分布规律和空腔结构的破坏形式,以国防工事和人防工事的等级设计规范为依据,设计了长方体单腔室空腔模型,并对该模型进行了药量逐渐递增直至可使结构破坏的内爆炸实验。用压力传感器和加速度传感器分别记录了单腔室壁面上爆炸载荷的压力时程曲线和结构壁面振动的加速度时程曲线,分析了壁面上爆炸载荷的分布规律以及模型结构的破坏形式,并将首个峰值的实测数据与理论计算和数值模拟结果进行了对比,探讨了3种研究方法产生误差的原因。

关键词：爆炸力学爆炸效应内爆炸典型空腔