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Enhancing betavoltaic nuclear battery performance with 3D P^(+)PNN^(+)multi-groove structure via carrier evolution

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Nuclear Science and Techniques 2023年第12期34卷 1-16页

作者： hou‑jun He Yun‑Cheng Han Xiao‑Yu Wang Yu‑Min Liu Jia‑Chen Zhang Lei Ren Ming‑Jie Zheng Hefei Institutes of Physical Science Chinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China School of Nuclear Science and Engineering East China University of TechnologyNanchang 330013China School of Nuclear Technology and Chemistry and Biology Hubei University of Science and TechnologyXianning 437100China

Betavoltaic nuclear batteries offer a promising alternative energy source that harnesses the power of beta particles emitted by *** satisfy the power demands of microelectromechanical systems(MEMS),3D structures have been proposed as a potential ***,this paper introduces a novel 3D^(63)Ni–SiC-based P^(+)PNN^(+)structure with a multi-groove design,avoiding the need for PN junctions on the inner surface,and thus reducing leakage current and power *** Carlo simulations were performed considering the fully coupled physical model to extend the electron–hole pair generation rate to a 3D structure,enabling the efficient design and development of betavoltaic batteries with complex 3D *** a result,the proposed model produces the significantly higher maximum output power density of 19.74μW/cm^(2) and corresponding short-circuit current,open-circuit voltage,and conversion efficiency of 8.57μA/cm^(2),2.45 V,and4.58%,respectively,compared with conventional planar *** analysis of the carrier transport and collection characteristics using the COMSOL Multiphysics code,we provide deep insights regarding power increase,and elucidate the discrepancies between the ideal and simulated performances of betavoltaic *** work offers a promising approach for the design and optimization of high-output betavoltaic nuclear batteries with a unique 3D design,and serves as a valuable reference for future device fabrication.

关键词： Betavoltaic nuclear battery High-output power density Three-dimensional structure Carrier drift–diffusion Carrier recombination Carrier collection efficiency

Numerical Simulations of Backward-to-Forward Leaky-Wave Antenna with Composite Right/Left-Handed Coplanar Waveguide

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Chinese Physics Letters 2010年第3期27卷 148-151页

作者：司黎明孙厚军吕昕 Department of Electronic Engineering School of Information Science and Technology Beijing Institute of Technology Beijing 100081 Electrical and Computer Engineering Department University of Arizona Tucson AZ 85721 USA

A composite right/left-handed （CRLH） coplanar waveguide （CPW） structure and its leaky-wave antenna （LWA） with continuous backward-to-forward scanning applications are proposed. The structure of the CRLH transmission line （TL） is composed of split-ring resonators （SRRs） for left-handed （LH） series capacitance and short-circuited stubs connected between the CPW central signal line and the ground for LH shunt inductance, while the unavoidable right-handed （RH） parasitic effects series inductance and shunt capacitance are generated by wave propagation through the host transmission line. The dispersion relations are calculated and compared with the equivalent circuit model method and 3D full-wave simulations, which can be used to determine the physical dimensions of the CRLH-CPW, such as in the balanced CRLH-TL case. As a main example, a CRLH-CPW-LWA operating from 1.67 GHz to 1.80 GHz with the dispersion characteristics of the balanced CRLH-TL case shows continuous leakage frequency band （fast wave region） from LH （phase constant β 〈0, .67〈f〈1.74 GHz） to RH （β〉0, 1.74〈f〈1.80 GHz） state through the transition frequency point （β=0, f=1.74 GHz）, whereas conventional LWAs operated in RH state only provide forward scanning capabilities （β〉0）.

关键词： Condensed matter: electrical magnetic and optical Electronics and devices Optics quantum optics and lasers

Chinese contribution to immune thrombocytopenia： the pathogenesis-oriented treatment

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Chinese Medical Journal 2013年第13期126卷 2564-2569页

作者： QIN Ping PENG jun hou Ming Department of Hematology Qilu Hospital Shandong University Jinan Shandong 250012 China

Primary immune thrombocytopenia （ITP） is the most common hemorrhagic disorder characterized byisolated thrombocytopenia in the absence of conditions known to cause thrombocytopenia. The incidence rate of ITP is similar in males and females; the incidence was significantly higher among patients older than 60 years） The clinical manifestation of bleeding varies with patient. The severity of bleeding ranges from mild mucocutanous bleeding （petechiae and ecchymoses） to life-threatening hemorrhages （intracranial or gastrointestinal bleeding）; some patients have no bleeding manifestations. Fatal and major nonfatal hemorrhages were extremely higher in patients older than 60 years old.2 The thrombocytopenia in ITP has been traditionally thought to be caused by the production of autoantibodyies targeting platelet antigens. Autoantibodies attach to the platelets and are destructed by macrophages in the reticuloendothelial system. Understanding of the mechanisms of thrombocytopenia in ITP has greatly expanded in recent years. The pathogenesis of ITP is heterogeneous and complex. The thrombocytopenia in ITP is caused not only by increased platelet destruction but also by impaired platelet production. The advances in the understanding of ITP have led to the development of a novel nonimmunologic therapeutic approach by stimulating platelet production and even revised guidelines in the diagnosis and treatment of ITE3 In the process of exploring the pathogenesis of ITP, the researchers from all over the world have done a lot of studies. This review will provide an insight into the pathogenesis-oriented treatment of ITP, mainly focusing on the studies of Chinese researchers.

关键词： immune thrombocytopenia pathogenesis treatment

A Comparison of Three Heuristic Algorithms for Molecular Docking

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Chinese Chemical Letters 1999年第7期10卷 615-618页

作者： Ting jun hou jun Mei WANG Xiao Jie XU(Department of Chemistry. Beida-Jiuyuan Molecular Design Laboratory. Peking University.Beijing 100871) Department of Chemistry Beida-Jiuyuan Molec. Des. Laboratory Peking University Beijing 100871 China

Three heuristic algorithms: simulated annealing, genetic algorithm, and Tabu search were compared to molecular docking procedure using 3 protein-ligand systems. Statistical analysis of the results indicated that the Tabu search showed the best performance in terms of locating solutions close to the crystallographic ligand conformation. From the comparisons, a hybrid search algorithm was proposed, which gave superior results compared with any one of the algorithms alone.

关键词： molecular docking genetic algorithm tabu search simulated annealing

Application of Genetic Algorithm to the QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcription Inhibitors

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Chinese Chemical Letters 1998年第7期9卷 651-654页

作者： Ting jun hou jun Mei WANG You Yong LI Xiao Jie XU(Chemistry department, Beida-Jiuyuan Molecular Design Laboratory, Peking University,Beijing 100871) Chemistry Department Beida-Jiuyuan Molec. Des. Laboratory Peking University Beijing 100871 China

Genetic Algorithm (GA) was used to study the quantitative structural parameters and activity relationship of pyrrolobenzothizepinones and pyrrolobenzoxazepinones's inhibitory activities with non-nucleoside HIV-1 reverse transcriptase (RT). A group of linear polynomial models with good relationship have been built to get some useful information that other methods can not offer.

关键词： QSAR GA(genetic algorithm) HIV

Gelatinized starch as a low-cost and bifunctional binder enables shuttle-free aqueous zinc-iodine batteries

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Rare Metals 2024年第12期43卷 6351-6361页

作者： Zheng-Tai Yu Zong-Shuai Gong Rui-Hang Wen Ya-jun hou Zhi-Qiang Luo Zhi-Hao Yuan Ning Zhang School of Materials Science and Engineering Tianjin University of Technology College of Chemistry and Materials Science Key Laboratory of Analytical Science and Technology of Hebei ProvinceInstitute of Life Science and Green DevelopmentHebei University

Rechargeable aqueous zinc-iodine（Zn-I2） batteries are widely regarded as a promising contender for energy-storage devices,due to their intrinsic safety,low cost,and high ***,the severe shuttle effect of polyiodides and the large volume change of I2cathode induce severe capacity loss and poor electrochemical reversibility,hindering their commercial ***,we report that the low-cost gelatinized starch（Gstarch） can be used as a bifunctional binder for Zn-I2batteries to circumvent the above problems *** on both calculation and experimental data,it is demonstrated that the double-helix structure of G-starch with both α-1,4-and α-1,6-glycosidic bonds can strongly interact with polyiodides to suppress the shuttle ***,the G-starch with multiple hydrogen-bonded cross-linking networks exhibits a much-enhanced adhesion ability and can buffer the volume expansion of active *** contrast,the traditional carboxymethyl cellulose sodium-based aqueous binder lacks these *** a result,the G-starch binder enables the aqueous Zn-I2battery to achieve a high reversible capacity of212.4 mAh·g-1at 0.2 A·g-1after 1000 cycles and ultralong-cycling life over 48,000 cycles with 135.4 mAh·g-1and 89.6% capacity retention at 2 A·*** work develops a simple yet efficient strategy to construct highperformance Zn-I2batteries.

关键词： Aqueous Zn metal batteries Binder Gelatinized starch Shuttle effect Zn–I2 batteries

Research on conflict resolution of collaborative design with fuzzy case-based reasoning method

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重庆邮电大学学报（自然科学版） 2009年第2期21卷 314-322页

作者： hou jun-ming SU Chong LIANG Shuang WANG Wan-shan School of Mechanical Engineering ＆ Automation Northeastern University Shenyang 110004 P. R. China

Collaborative design is a new style for modern mechanical design to meet the requirement of increasing competition. Designers of different places complete the same work, but the conflict appears in the process of design which may interface the design. Case-based reasoning (CBR) method is applied to the problem of conflict resolution, which is in the artificial intelligence field. However, due to the uncertainties in knowledge representation, attribute description, and similarity measures of CBR, it is very difficult to find the similar cases from case database. A fuzzy CBR method was proposed to solve the problem of conflict resolution in collaborative design. The process of fuzzy CBR was introduced. Based on the feature attributes and their relative weights determined by a fuzzy technique, a fuzzy CBR retrieving mechanism was developed to retrieve conflict resolution cases that tend to enhance the functions of the database. By indexing, calculating the weight and defuzzicating of the cases, the case similarity can be obtained. Then the case consistency was measured to keep the right result. Finally, the fuzzy CBR method for conflict resolution was demonstrated by means of a case study. The prototype system based on web is developed to illustrate the methodology.

关键词：模糊推理方法协同设计案例基于事例推理特征属性检索机制机械设计接口设计

Stable Initialization Scheme for K-Means Clustering

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Wuhan University Journal of Natural Sciences 2009年第1期14卷 24-28页

作者： XU junling XU Baowen ZHANG Weifeng ZHANG Wei hou jun School of Computer Science and Engineering Southeast University Nanjing 211189 Jiangsu China State Key Laboratory of Software Engineering Wuhan University Wuhan 430072 Hubei China Department of Computer Nanjing University of Posts and Telecommunications Nanjing 210003 Jiangsu China

Though K-means is very popular for general clustering, its performance, which generally converges to numerous local minima, depends highly on initial cluster centers. In this paper a novel initialization scheme to select initial cluster centers for K-means clustering is proposed. This algorithm is based on reverse nearest neighbor （RNN） search which retrieves all points in a given data set whose nearest neighbor is a given query point. The initial cluster centers computed using this methodology are found to be very close to the desired cluster centers for iterative clustering algorithms. This procedure is applicable to clustering algorithms for continuous data. The application of the proposed algorithm to K-means clustering algorithm is demonstrated. An experiment is carried out on several popular datasets and the results show the advantages of the proposed method.

关键词： clustering unsupervised learning K-means initialization

Inhibitory effects of chloroquine on the activation of plasmacytoid dendritic cells in SIVmac239-infected Chinese rhesus macaques

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Cellular & Molecular Immunology 2012年第5期9卷 410-416页

作者： Jian-Ping Ma hou-jun Xia Gao-Hong Zhang Jian-Bao Han Li-Guo Zhang Yong-Tang Zheng Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences&Yunnan Province Kunming Institute of ZoologyChinese Academy of SciencesKunmingChina Graduate University of the Chinese Academy of Sciences BeijingChina CAS Key Laboratory of Infection and Immunity Institute of BiophysicsChinese Academy of SciencesBeijingChina

It is currently widely accepted that immune activation in HIV-infected individuals leads to a severe loss of CD4＋ T cells and the progression to AIDS. However, the underlying mechanism of this immune activation remains unclear. Experimental data suggest that the activation of plasmacytoid dendritic cells （pDCs） by plasma viremia may play a critical role in HIV-induced immune activation. In this study, we found that the level of immune activation was higher in the late phase of SIVmac239 infection compared with chronic infection, which suggests that immune activation might be related to disease progression in SIVmac239-infected non-human primate models. Our work also showed that chloroquine could effectively inhibit the activation of pDCs in vitro and in vivo. However, chloroquine treatment of SIVmac239-infected macaques had no significant influence on the Cellular composition of peripheral blood in these animals.

关键词： Chinese rhesus macaque chloroquine immune activation pDC SIV