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基于脑肠轴探讨肠道菌群调控腹泻型肠易激综合征的研究进展

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中国民族民间医药 2024年第19期33卷 59-65页

作者：王宏吉曹波贵州中医药大学贵州贵阳550002 贵州中医药大学第一附属医院贵州贵阳550000

腹泻型肠易激综合征是以内脏高敏感性为主要发病机制的一种肠道功能紊乱性疾病,主要临床表现为精神刺激引发的腹痛腹泻,与中医学中肝郁脾虚型泄泻症状高度相似。近期有研究指出,在腹泻型肠易激综合征发病机制中,脑肠轴紊乱导致的内脏高... 详细信息

腹泻型肠易激综合征是以内脏高敏感性为主要发病机制的一种肠道功能紊乱性疾病,主要临床表现为精神刺激引发的腹痛腹泻,与中医学中肝郁脾虚型泄泻症状高度相似。近期有研究指出,在腹泻型肠易激综合征发病机制中,脑肠轴紊乱导致的内脏高敏感性是关键,肠道菌群失调亦会引起和加剧内脏高敏感性。文章就中枢和外周调控内脏高敏性的角度分析了肠道菌群对脑肠轴5-HT的调控作用,进一步丰富腹泻型肠易激综合征的中医药治疗理论,为临床诊疗提供新思路。

关键词：腹泻型肠易激综合征脑肠轴内脏高敏感性肠道菌群 5-羟色胺

Investigation of hydrolysis conditions and properties on protein hydrolysates from flatfish skin

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Frontiers of Chemical Science and Engineering 2013年第3期7卷 303-311页

作者： Hua ZHANG hongji ZHU Shipeng wang Weihua wang Key Laboratory of Systems Bioengineering (Ministry of Education) School of Chemical Engineering and Technology Tianjin University Tianjin 300072 China

Response surface method （RSM）, based on Box-Behnken design, was used to optimize the enzymatic hydrolysis conditions of flatfish skin protein hydrolysates （FSPH）. Among the tested proteases, the combination of nutrase and trypsin was selected. The optimal hydrolysis conditions were as follows： pH 7.3, temperature 51.8℃, and the enzyme/substrate （E/S） ratio 2.5; under these conditions, the maximum peptide yield （PY） was 69.41 =1：0.43%. The physiochemical analysis showed that the amino acids （His, Asp and Glu） of FSPH accounted for 18.15%, and FSPH was a mixture of polypeptides mostly distributed among 900-2000 Da. FSPH could exhibit a 93% chelating effect on ferrous ion at a concentration of 400 gg/mL, and also a notable reducing power. This study showed bioprocess for the production of FSPH for the first time, which had a good potential for valuable ingredients in the food, cosmetic and medicine industries.

关键词： flatfish skin protein hydrolysates metal chelating activity reducing power

Analysis of electromagnetic propagation in birefringent thin film

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Science China(Physics,Mechanics & Astronomy) 2005年第5期48卷 513-520页

作者： QI hongji wang Jianguo SHAO Jianda FAN Zhengxiu Shanghai Institute of Optics and Fine Mechanics Shanghai 201800 China Shanghai Institute of Optics and Fine Mechanics Shanghai 201800 China Shanghai Institute of Optics and Fine Mechanics Shanghai 201800 China Shanghai Institute of Optics and Fine Mechanics Shanghai 201800 China

In general, the propagating behavior of extraordinary wave in anisotropic materials is different from that in isotropic materials. With the tangential continuity of Maxwell’s equations, the electromagnetic propagating behaviors have been investigated at the incident and exit interfaces of the uniaxial anisotropic thin film. The emphasis was placed on two interesting optical phenomena such as homolateral refraction behavior and wide-angle Brewster’s phenomenon, which occurred at the interfaces of uniaxial anisotropic thin film.

关键词： birefringent thin film, interface, homolateral refraction behavior, wide-angle Brewster's phenomenon.

Two-Way Coupling Vortex Method and Its Application

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Journal of Thermal Science 1992年第3期1卷 160-165页

作者： Chenggang Xu (1) Chuanjun Yan (1) hongji wang (1) 1. Northwestern Polytechnical University 710072 Xi’an China

Because of the success of the discrete vortex method for the simulation of large-scale vortex structure, many researchers extend this method to two-phase flow simulations, especially, to the simulation of particle dispersion in mixing layer, which is characterized by large-scale vortex structure. But the previous work is limited to one-way coupling, which neglects the effect of particles on fluid flow. In this paper, a discrete vortex method involving two-way coupling for two-phase flows is first proposed and then used in numerical simulation of two-dimensional gas-particle mixing layers. The numerical results show that the introduction of particles into the mixing layer has significant effects on the creation, development and merging process of large-scale vortex structures. It makes the mean size of large-scale vortex structure larger and the distance needed for development of large-scale vortex structure shorter.

关键词： discrete vortex method shear layer turbulence coherent structure.

Review on Dynamic Modeling and Vibration Characteristics of Rotating Cracked Blades

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Journal of Dynamics, Monitoring and Diagnostics 2023年第4期2卷 207-227页

作者： Hui Ma Zhiyuan Wu Jin Zeng Weiwei wang hongji wang Hong Guan Wenming Zhang School of Mechanical Engineering and Automation Northeastern UniversityShenyangLiaoning 110819People’s Republic of China Key Laboratory of Vibration and Control of Aero-Propulsion Systems Ministry of Education of China Northeastern UniversityShenyangLiaoning 110819People’s Republic of China State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China School of Mechanics and Engineering Southwest Jiaotong UniversityChengdu 610031People’s Republic of China

As one of the most important parts in the engine,the structure and state of the rotating blade directly affect the normal performance of the *** order to monitor engine crack failure and ensure flight safety,it is necessary to carry out research on the dynamic modeling of the cracked blade and breathing crack-induced vibration *** paper summarizes the current research status on the dynamics of cracked blade,and the related topics mainly include four aspects:crack propagation path,mechanical model of open and breathing cracks,dynamic modeling methods of cracked blades such as lumped mass model,semi-analytical model and finite element model,and dynamic characteristics of cracked *** review will provide valuable references for future studies on dynamics and fault diagnosis of cracked blade in aeroengine.

关键词： breathing crack crack propagation cracked blade dynamic characteristics dynamic modeling

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分解弱可逆有限自动机的两个结果

计算机研究与发展 2005年第4期42卷 690-696页

作者：王鸿吉中国科学院软件研究所

研究弱可逆有限自动机的分解可以为分析有限自动机公开钥密码体制的安全性提供一种重要途径.从输出权的角度研究了n元延迟τ步弱可逆有限自动机M的分解问题,首先证明了其可分解为一个延迟0步弱可逆有限自动机和一个τ阶延迟元当且仅当M... 详细信息

研究弱可逆有限自动机的分解可以为分析有限自动机公开钥密码体制的安全性提供一种重要途径.从输出权的角度研究了n元延迟τ步弱可逆有限自动机M的分解问题,首先证明了其可分解为一个延迟0步弱可逆有限自动机和一个τ阶延迟元当且仅当M的所有状态的长τ输出权为1.其次,在获得一类不可分解出延迟元的弱可逆有限自动机的基础上,构造出一个反例,否定回答了鲍丰在1993年提出的一个公开问题.同时给出了二元严格延迟τ步强连通弱可逆有限自动机可分解为一个严格延迟τ-1步弱可逆有限自动机和一个严格延迟1步弱可逆有限自动机的一个充分条件.

关键词：有限自动机弱可逆延迟分解输出权

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NHD开发应用前景及市场分析

现代化工 1999年第7期19卷 42-43页

作者：王洪记山东鲁化集团公司研究所

ＮＨＤ（商品名）是一种新型高效物理吸收溶剂，化学名称为聚乙二醇二甲醚，是多种醚的混合物。通常为淡黄色液体，接近中性，物化性质稳定，对钢材无腐蚀且有润滑作用。具有无毒、不污染环境、比热容低、蒸汽压低、粘度小、再生耗热少... 详细信息

ＮＨＤ（商品名）是一种新型高效物理吸收溶剂，化学名称为聚乙二醇二甲醚，是多种醚的混合物。通常为淡黄色液体，接近中性，物化性质稳定，对钢材无腐蚀且有润滑作用。具有无毒、不污染环境、比热容低、蒸汽压低、粘度小、再生耗热少等优点。作为一种优良的有机溶剂，适...

关键词： NHD 聚乙二醇二甲醚市场分析

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醋酸生产技术及产需现状

现代化工 2000年第4期20卷 40-42,44页

作者：王洪记水煤浆气化及煤化工国家工程研究中心滕州277527

概要地介绍并评述了国内外醋酸生产技术及发展动向 ;统计并推测了全球醋酸生产能力、供需情况及开工率下降趋势 ;报道了我国近几年醋酸生产能力的发展情况及所采用的生产工艺 ,并对如何调整工艺构成比和生产装置的规模。

关键词：生产市场乙酸产需现状中国

Effect of Reduction Atmosphere on Properties of High Chrome Bricks

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China's Refractories 2010年第3期19卷 10-13页

作者： YIN hongji wang Jinxiang SHI Pengkun Henan Key Laboratory of Advanced Refractories Sinosteel Luoyang Institute of Refractories Research Co. Ltd. Luoyang 471039 China

The high chrome bricks specimens were prepared by firing at 1 350,1 450 and 1 550 ℃ in carbon embedded condition and at 1 700 ℃ in air,respectively. Effects of firing atmospheres （carbon embedded and air） on bulk density,apparent porosity,cold crushing strength,and slag penetration resistance of high chrome bricks were researched in order to improve physical properties and corrosion resistance of high chrome bricks and to prolong the service life in slagging coal gasifier. The results show that with temperature rising,the apparent porosity of specimens decreases and the bulk density increases; the cold crushing strength of the specimens carbon embedded fired at 1 450 ℃ is the highest,reaching 214 MPa; carbon embedded condition is beneficial to reducing the sintering temperature and improving the microstructure; the specimens carbon embedded fired at 1 450 ℃ perform better slag penetration resistance than the specimens fired at 1 700 ℃ in air.

关键词： Reduction atmosphere High chrome bricks Microstructure Penetration resistance