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超声引导安珂旋切术对乳腺良性肿物手术患者术后康复进程及并发症发生率的影响

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四川生理科学杂志 2024年第3期46卷 620-623页

作者：鲁仰昆张筱扬洪秋雁周口东新医院普外科河南周口466000 河南大学第一附属医院甲乳外科河南开封475000 周口市妇幼保健院麻醉科河南周口466000

目的:探究超声引导安珂旋切术对乳腺良性肿物手术患者术后康复进程及并发症发生率的影响.方法:选取我院2018年4月至2020年4月期间收治的94例乳腺良性肿物患者作为研究对象,按照手术方法不同分为研究组和对照组,各47例.研究组接受超声引... 详细信息

目的:探究超声引导安珂旋切术对乳腺良性肿物手术患者术后康复进程及并发症发生率的影响.方法:选取我院2018年4月至2020年4月期间收治的94例乳腺良性肿物患者作为研究对象,按照手术方法不同分为研究组和对照组,各47例.研究组接受超声引导安珂旋切术,对照组接受传统切除术,比较两组围术期指标、术后康复状况、视觉模拟法(Visual analogue scale,VAS)评分、炎性因子水平、切口满意度及并发症发生率.结果:研究组术后1 m腔内积液量、切口愈合时间明显低于对照组(P<0.05);研究组切口长度、手术时间、住院时间、术中出血量均明显少于对照组(P<0.05);研究组术后6 h、24 h VAS评分均明显低于对照组(P<0.05);研究组并发症总发生率明显低于对照组(P<0.05);研究组切口满意度明显高于对照组(P<0.05);术后3 d,研究组炎性因子神经肽Y、前列腺素E2、白细胞介素-10水平均明显低于对照组(P<0.05).结论:乳腺良性肿物患者采用超声引导安珂旋切术可缩短手术时间,减少术中出血量,减轻疼痛程度,降低炎性因子水平,促进术后康复,减少并发症的发生.

关键词：并发症超声引导乳腺良性肿物安珂旋切术术后康复

“潜阳法”治疗便秘型肠易激综合征的思路探析

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广州中医药大学学报 2024年第6期41卷 1628-1631页

作者：王楠张书信高静陈航洪燕秋北京中医药大学东直门医院肛肠科北京100700 北京中医药大学北京100029 北京中医药大学厦门医院肛肠科福建厦门361015

便秘型肠易激综合征是指临床表现以腹痛或腹胀、排便习惯改变等为主的慢性功能性肠道综合征,此病属反复发作的难治性疾病。临证中症见大便秘结、排便困难、腹痛或腹胀,但无发热、口渴、烦躁等症的久病及老年便秘型肠易激综合征的患者,... 详细信息

便秘型肠易激综合征是指临床表现以腹痛或腹胀、排便习惯改变等为主的慢性功能性肠道综合征,此病属反复发作的难治性疾病。临证中症见大便秘结、排便困难、腹痛或腹胀,但无发热、口渴、烦躁等症的久病及老年便秘型肠易激综合征的患者,其病机可归为肾阴失藏,相火离位,浮于大肠,暗耗津液;辨证属“阴不藏阳,虚阳浮越”之证,治疗宜采用潜阳法;选方可采用三才封髓汤(主要由人参、天冬、熟地黄、黄柏、砂仁、甘草等组成)加减,常可获显效。

关键词：便秘型肠易激综合征虚阳浮越相火潜阳法三才封髓汤

Risk Factors of Depression Screened by Two-Sample Mendelian Randomization Analysis:A Systematic Review

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Biomedical and Environmental Sciences 2024年第1期37卷 85-95页

作者： WANG Han Lin XUE yan Feng CUI Bao qiu LIU hong SHEN Xin Xin Shandong Provincial Research Center for Bioinformatic Engineering and Technique School of Life SciencesShandong University of TechnologyZibo 255049ShandongChina Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical UniversityTaiyuan 030013ShanxiChina State Key Laboratory of Infectious Disease Prevention and Control National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China

Objective This study explored the potentially modifiable factors for depression and major depressive disorder(MDD)from the MR-Base database and further evaluated the associations between drug targets with *** We analyzed two-sample of Mendelian randomization(2SMR)using genetic variant depression(n=113,154)and MDD(n=208,811)from Genome-Wide Association Studies(GWAS).Separate calculations were performed with modifiable risk factors from MR-Base for 1,001 *** MR analysis was performed by screening drug targets with MDD in the DrugBank database to explore the therapeutic targets for *** variance weighted(IVW),fixed-effect inverse variance weighted(FE-IVW),MR-Egger,weighted median,and weighted mode were used for complementary *** The potential causal relationship between modifiable risk factors and depression contained 459 results for depression and 424 for ***,the associations between drug targets and MDD showed that SLC6A4,GRIN2A,GRIN2C,SCN10A,and IL1B expression are associated with an increased risk of *** contrast,ADRB1,CHRNA3,HTR3A,GSTP1,and GABRG2 genes are candidate protective factors against *** This study identified the risk factors causally associated with depression and MDD,and estimated 10 drug targets with significant impact on MDD,providing essential information for formulating strategies to prevent and treat depression.

关键词： Risk factors Drug targets Depression Major depressive disorder Two-sample Mendelian randomization

Model-driven path planning for robotic plasma cutting of branch pipe with single Y-groove based on pipe-rotating scheme

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Advances in Manufacturing 2024年第1期12卷 94-107页

作者： yan Liu qiu Tang Xin-Cheng Tian School of Control Science and Engineering Shandong UniversityJinan250061People’s Republic of China Engineering Research Center of Intelligent Unmanned System Ministry of EducationJinan250061People’s Republic of China School of Mechanical and Electronic Engineering Shandong Jianzhu UniversityJinan250101People’s Republic of China

The automatic cutting of intersecting pipes is a challenging task in *** improved automation and accuracy,this paper proposes a model-driven path planning approach for the robotic plasma cutting of a branch pipe with a single ***,it summarizes the intersection forms and introduces a dual-pipe intersection *** on this model,the moving three-plane structure(a description unit of the geometric characteristics of the intersecting curve)is constructed,and a geometric model of the branch pipe with a single Y-groove is ***,a novel mathematical model for plasma radius and taper compensation is ***,the compensation model and groove model are integrated by establishing movable ***,to prevent collisions between the plasma torch and workpiece,the torch height is planned and a branch pipe-rotating scheme is *** the established models and moving frames,the planned path description of cutting robot is provided in this novel *** accuracy of the proposed method is verified by simulations and robotic cutting experiments.

关键词： Automatic groove cutting of intersecting pipes Model-driven robot path planning Plasma beam radius and taper compensation

Hydrogen production from hydrolysis of NaBH_(4) solution over Co-Fe-B@g-C_(3)N_(4)/NF thin film catalyst

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Rare Metals 2024年第6期43卷 2648-2659页

作者： yan Wang Jia-Xin Ma Jian Ren Di Zhang Feng-yan Xu Ke Zhang Zhong-qiu Cao qiu-Ju Sun Guo-De Li Shi-Wei Wu hong-Hui Chen College of Chemistry and Chemical Engineering Shenyang Normal UniversityShenyang 110034China Experimental Center Shenyang Normal UniversityShenyang 110034China Hunan Shande Energy Storage New Materials Research Institute Limited Company Changde 415000China

In this study,the double loaded Co-Fe-B@g-C_(3)N_(4)/NF(NF:Ni foam)thin film catalysts were prepared for the first time via chemical deposition method at room *** optimizing the reducing agent concentration to 0.9 mol·L^(-1),the as-obtained Co-Fe-B@g-C_(3)N_(4)/NF exhibited the twisted ribbon structure with more distinct three-dimensional hierarchy and the smaller particle size,showing the good catalytic property for the hydrolysis of NaBH_(4)*** H_(2)generation rate of Co-Fe-B@g-C_(3)N_(4)/NF and binary Co-B@g-C_(3)N_(4)/NF under visible light irradiation surpassed the value under natural *** apparent activation energy of Co-Fe-B@g-C_(3)N_(4)/NF(45.0 kJ·mol^(-1))under visible light irradiation was obviously reduced when compared with the natural condition(48.4 kJ·mol^(-1))and binary Co-B@g-C_(3)N_(4)/NF(60.6 kJ·mol^(-1))under visible light ***,the catalytic performance of the optimized Co-Fe-B@g-C_(3)N_(4)/NF thin film catalyst was superior to most of the reported non-noble metal and even noble metal ***,it illustrated that the catalytic H_(2)production performance of Co-Fe-B@g-C_(3)N_(4)/NF thin film was distinctly improved after the introduction of light and multicomponent recombination.

关键词： Sodium borohydride Co-Fe-B@g-C_(3)N_(4)/NF catalyst Chemical deposition Hydrogen production

Sirolimus can promote the disappearance of renal angiomyolipoma associated with tuberous sclerosis complex:a prospective cohort study

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World Journal of Pediatrics 2024年第6期20卷 602-610页

作者： Shuo Dun yang-yang Wang Lin Wan qiu-hong Wang Qian Lu Xiao-yan yang Qi Zhang Hui-Min Chen Lu-Peng qiu Li-Ping Zou Medical School of Chinese PLA Beijing 100853China Department of Pediatrics The First Medical CenterChinese PLA General HospitalBeijing 100853China Center of Epilepsy Beijing Institute for Brain DisordersBeijing 100069China

Background Renal angiomyolipoma(RAML)is the most common kidney lesion in patients with tuberous sclerosis complex(TSC),affecting about 80%of *** is a benign tumor that grows over time,usually bilaterally,and can easily lead to kidney complications such as acute ***,we investigated the efficacy and safety of sirolimus in children with TSC-associated RAML and explored the factors affecting tumor disappearance under sirolimus treatment through subgroup *** A prospective cohort study was *** was initiated at 1 mg/(m^(2)×day),and dose adjustments were made by a 2-week titration period to attain a trough blood concentration of 5-10 ng/*** disappearance of RAML in chil-dren after sirolimus treatment was observed,and Cox regression was used to screen the factors affecting tumor *** One hundred and twenty-six patients who met the criteria were *** 3 months,6 months,12 months,and 24 months of follow-up,tumors disappeared in 18(14.3%),30(23.8%),39(31.0%),and 42(33.3%)children,*** disappeared in 50(39.7%)children by the last visit of each individual,and 30(60%)of them occurred within 6 *** multivariate Cox regression analysis showed that patients with a smaller maximum tumor diameter at baseline had a higher tumor disappearance ***-six(29%)patients had stomatitis during the entire treatment period,and no serious *** Sirolimus could promote the disappearance of TSC-related *** disappearance rate was correlated with the maximum diameter at baseline,and the smaller the tumor was,the higher the disappearance *** is well tolerated in the treatment of RAML associated with TSC.

关键词： Angiomyolipoma mTOR inhibitor Sirolimus Tuberous sclerosis

Clustering for Bivariate Functional Data

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 613-629页

作者： Shi-yun CAO yan-qiu ZHOU yan-ling WAN Tao ZHANG School of Science Guangxi University of Science and TechnologyLiuzhou 545006China School of Marxism Guangxi University of Science and TechnologyLiuzhou 545006China Key Laboratory of Intelligent Information Processing and Graph Processing Guangxi University of Science and TechnologyLiuzhou 545006China

In this paper,we consider the clustering of bivariate functional data where each random surface consists of a set of curves recorded repeatedly for each *** k-centres surface clustering method based on marginal functional principal component analysis is proposed for the bivariate functional data,and a novel clustering criterion is presented where both the random surface and its partial derivative function in two directions are *** addition,we also consider two other clustering methods,k-centres surface clustering methods based on product functional principal component analysis or double functional principal component *** results indicate that the proposed methods have a nice performance in terms of both the correct classification rate and the adjusted rand *** approaches are further illustrated through empirical analysis of human mortality data.

关键词： bivariate functional data -centres surface clustering functional principal component analysis partial derivative function

Robust-augmentation nonlinear dynamic inversion control of over-actuated coaxial high-speed helicopter in transition mode

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Chinese Journal of Aeronautics 2024年第8期37卷 404-420页

作者： Yuqing qiu yan LI Jinxi LANG Yuxian LIU Zhong WANG School of Automation Northwestern Polytechnical UniversityXi’an 710129China

As the elevator and rudder can be used actively for control,in addition to the rotors,Coaxial High-speed Helicopters(CHHs)have the problems of control redundancy and changing control authority in the transition *** paper presents a robust-augmentation transitioning flight control design for a CHH under the adverse conditions of parametric uncertainties and external ***,based on control characteristic analysis,an Adaptive Filtered Nonlinear Dynamic Inversion(AFNDI)controller is proposed for the angular rate to handle the effect of unknown unstructured uncertainties and external *** analysis proves that the presented angular rate controller can guarantee steady-state and transient ***,the attitude angle and velocity controllers are also ***,an Incremental-based Nonlinear Prioritizing Control Allocation(INPCA)method is designed to take into account control surface transition and changing control authority,which efficiently distributes the required moments between coaxial rotors and aero-surfaces,and avoids the control reversal problem of the yaw *** the proposed control architecture,the low-pass filter is introduced to alleviate the adverse influence of time delay and measurement ***,the effectiveness of the proposed controller is demonstrated through nonlinear numerical simulations,and is compared with existing *** results show that the proposed control law can improve both capabilities of disturbance rejection and fast response,and works satisfactorily for the CHH transitioning control characteristic.

关键词： Coaxial high-speed helicopter Transition mode Attitude control Control allocation Robust adaptive control

Effects of Hydrogen Charging Time and Pressure on the Hydrogen Embrittlement Susceptibility of X52 Pipeline Steel Material

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Acta Metallurgica Sinica(English Letters) 2024年第2期37卷 293-307页

作者： hong-Jiang Wan Xiao-Qi Wu hong-Liang Ming Jian-qiu Wang En-Hou Han School of Materials Science and Engineering University of Science and Technology of ChinaShenyang110016China CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang110016China School of Materials Science and Engineering Northeastern UniversityShenyang110819China Institute of Corrosion Science and Technology Guangzhou510530China

The effects of hydrogen charging time and pressure on the hydrogen embrittlement(HE)susceptibility of X52 pipeline steel material are studied by slow strain rate tensile *** fracture morphologies of the specimens are observed by scanning electron *** HE susceptibility of the X52 pipeline steel material increases with an increase in both hydrogen charging time and hydrogen *** a charging time of 96 h,the HE susceptibility index reaches 45.86%,approximately 3.6 times that at a charging time of 0 ***,a charging pressure of 4 MPa results in a HE susceptibility index of 31.61%,approximately 2.5 times higher than that at a charging pressure of 0.3 MPa.

关键词： Hydrogen embrittlement X52 pipeline steel material Tubular specimen Hydrogen charging time Hydrogen charging pressure