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Journal of the Operations Research Society of China 2024年第2期12卷 495-504页

作者： hong-ye Zheng Suo-Gang Gao Wen Liu Bo Hou School of Mathematical Sciences Hebei Normal UniversityShijiazhuang 050024HebeiChina

In this paper,we consider the parallel-machine customer order scheduling with delivery time and submodular rejection *** this problem,we are given m dedicated machines in parallel and n customer *** order has a delivery time and consists of m product types and each product type should be manufactured on a dedicated *** order is either rejected,in which case a rejection penalty has to be paid,or accepted and manufactured on the m dedicated *** objective is to find a solution to minimize the sum of the maximum delivery completion time of the accepted orders and the penalty of the rejected orders which is determined by a submodular *** design an LP rounding algorithm with approximation ratio of n+1 for this problem.

关键词： Order scheduling Delivery time Submodular rejection penalty Approximation algorithm

High-order time-reversal symmetry breaking normal state

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Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 136-148页

作者： Meng Zeng Lun-Hui Hu hong-ye Hu Yi-Zhuang You Congjun Wu Department of Physics University of CaliforniaSan DiegoCalifornia 92093USA Department of Physics Zhejiang UniversityHangzhou 310058China New Cornerstone Science Laboratory Department of PhysicsSchoolof ScienceWestlake UniversityHangzhou 30024China Institute for Theoretical Sciences Westlake UniversityHangzhou 310024China Key Laboratory for Quantum Materials of Zhejiang Province School of ScienceWestlake UniversityHangzhou 310024China Institute of Natural Sciences Westlake Institute for Advanced StudyHangzhou 310024China

Spontaneous time-reversal symmetry breaking plays an important role in studying strongly correlated unconventional *** two superconducting gap functions with different symmetries compete,the relative phase channel(θ_(-)≡θ_(1)-θ_(2))exhibits an Ising-type Z_(2) symmetry due to the second order Josephson coupling,where θ_(1,2) are the phases of two gap *** contrast,the U(1) symmetry in the channel of θ_(+)≡(θ_(1)+θ_(2))/2 is *** phase locking,i.e.,ordering of θ_(-),can take place in the phase fluctuation regime before the onset of superconductivity,i.e.,when θ_(+) is *** θ_(-) is pinned at ±π/2,then timereversal symmetry is broken in the normal state,otherwise,if θ_(-)=0,or,π,rotational symmetry is broken,leading to a nematic normal *** both cases,the order parameters possess a 4-fermion structure beyond the scope of mean-field theory,which can be viewed as a high order symmetry *** employ an effective two-component XY-model assisted by a renormalization group analysis to address this *** a natural by-product,we also find the other interesting intermediate phase corresponds to ordering of θ_+ but with θ_(-)*** is the quartetting,or,charge-4e,superconductivity,which occurs above the low temperature Z_(2)-breaking charge-2e superconducting *** results provide useful guidance for studying novel symmetry breaking phases in strongly correlated superconductors.

关键词： superconductivity strong correlation time-reversal breaking charge-4e

Large-field objective lens for multi-wavelength microscopy at mesoscale and submicron resolution

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Opto-Electronic Advances 2024年第6期7卷 41-56页

作者： Xin Xu Qin Luo Jixiang Wang Yahui Song hong ye Xin Zhang Yi He Minxuan Sun Ruobing Zhang Guohua Shi School of Biomedical Engineering(Suzhou) Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230026China Jiangsu Key Laboratory of Medical Optics Suzhou Institute of Biomedical Engineering and TechnologyChinese Academy of ScienceSuzhou 215163China

Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 *** restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain *** addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in *** we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 *** achieved a resolution of 0.74μm in fluorescent beads *** versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging *** mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.

关键词： mesoscopic objective lens large field-of-view high resolution multi-wavelength wide-field microscopy confocal laser scanning microscopy

Discussions on the Construction of“Double-Qualified”Teachers in Higher Vocational Colleges

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Journal of Contemporary Educational Research 2024年第7期8卷 234-239页

作者： hong ye Yuan Zhong Yanping Chen Wuhan Technical College of Communications Wuhan 430065Hubei ProvinceChina Guanqiao Town Central Kindergarten(Jiayu) Xianning 437224Hubei ProvinceChina

Creating a“double-qualified”teacher team is an important content in the construction of a higher vocational college teacher *** paper probes into the significance of the construction of“double-qualified”teachers in higher vocational colleges,and deeply analyzes the problems existing in the construction of“double-qualified”teachers’training base,the institutionalization of“double-qualified”teacher rotation training,the regularization of cooperation with enterprises,and the rationalization of incentive ***,it is of great practical significance to strengthen the theoretical research and practical exploration of the construction of“double-qualified”teachers.

关键词： “Double-qualified”teachers Team construction Higher vocational colleges

Unified deep learning model for predicting fundus fluorescein angiography image from fundus structure image

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Journal of Innovative Optical Health Sciences 2024年第3期17卷 105-113页

作者： Yiwei Chen Yi He hong ye Lina Xing Xin Zhang Guohua Shi Jiangsu Key Laboratory of Medical Optics Suzhou Institute of Biomedical Engineering and TechnologyChinese Academy of SciencesSuzhou 215163P.R.China School of Biomedical Engineering(Suzhou) Division of Life Sciences and MedicineUniversity of Science and Technology of China Hefei 230026P.R.China Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of SciencesShanghai 200031P.R.China

The prediction of fundus fluorescein angiography(FFA)images from fundus structural images is a cutting-edge research topic in ophthalmological image *** comprises estimating FFA from fundus camera imaging,single-phase FFA from scanning laser ophthalmoscopy(SLO),and three-phase FFA also from *** many deep learning models are available,a single model can only perform one or two of these prediction *** accomplish three prediction tasks using a unified method,we propose a unified deep learning model for predicting FFA images from fundus structure images using a supervised generative adversarial *** three prediction tasks are processed as follows:data preparation,network training under FFA supervision,and FFA image prediction from fundus structure images on a test *** comparing the FFA images predicted by our model,pix2pix,and CycleGAN,we demonstrate the remarkable progress achieved by our *** high performance of our model is validated in terms of the peak signal-to-noise ratio,structural similarity index,and mean squared error.

关键词： Fundus fluorescein angiography image fundus structure image image translation unified deep learning model generative adversarial networks

Risk factors and risk prediction model for mucocutaneous separation in enterostomy patients:A single center experience

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World Journal of Clinical Cases 2024年第33期12卷 6620-6628页

作者： Yun Liu hong Li Jin-Jing Wu Jian-hong ye Department of Reconstructive Hand and Plastic SurgeryZhejiang Chinese Medical UniversityLishui Central Hospital289 Kuocang RoadLiandu DistrictLishui 323000Zhejiang ProvinceChina Department of Operation Room Zhejiang Chinese Medical UniversityLishui Central Hospital289 Kuocang RoadLiandu DistrictLishui 323000Zhejiang ProvinceChina

BACKGROUND Mucocutaneous separation(MCS)is a common postoperative complication in enterostomy patients,potentially leading to significant *** identification of risk factors is crucial for preventing this ***,predictive models for MCS remain *** To construct a risk prediction model for MCS in enterostomy patients and assess its clinical predictive *** A total of 492 patients who underwent enterostomy from January 2019 to March 2023 were included in the *** were divided into two groups,the MCS group(n=110),and the non-MCS(n=382)based on the occurrence of MCS within the first 3 weeks after *** and multivariate analyses were used to identify the independent predictive factors of MCS and the model *** operating characteristic curve analysis was used to assess the model’s *** The postoperative MCS incidence rate was 22.4%.Suture dislodgement(P<0.0001),serum albumin level(P<0.0001),body mass index(BMI)(P=0.0006),hemoglobin level(P=0.0409),intestinal rapture(P=0.0043),incision infection(P<0.0001),neoadjuvant therapy(P=0.0432),stoma site(P=0.0028)and elevated intra-abdominal pressure(P=0.0395)were potential predictive factors of *** dislodgement[P<0.0001,OR:28.007595%CI:(11.0901-82.1751)],serum albumin level(P=0.0008,OR:0.3504,95%CI:[0.1902-0.6485]),BMI[P=0.0045,OR:2.1361,95%CI:(1.2660-3.6235)],hemoglobin level[P=0.0269,OR:0.5164,95%CI:(0.2881-0.9324)],intestinal rapture[P=0.0351,OR:3.0694,95%CI:(1.0482-8.5558)],incision infection[P=0.0179,OR:0.2885,95%CI:(0.0950-0.7624)]and neoadjuvant therapy[P=0.0112,OR:1.9769,95%CI:(1.1718-3.3690)]were independent predictive factors and included in the *** model had an area under the curve of 0.827 and good clinical utility on decision curve *** The mucocutaneous separation prediction model constructed in this study has good predictive performance and can provide a reference for early warning of mu

关键词： Enterostomy Mucocutaneous separation Risk assessment model Performance validation

Discussion on Talent Training Mode of Engineering Cost Major in Higher Vocational Colleges

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Journal of Contemporary Educational Research 2024年第9期8卷 181-185页

作者： Zhe Yang Yuan Zhong hong ye Wuhan Technical College of Communications Wuhan 430065Hubei ProvinceChina Guanqiao Town Central Kindergarten(Jiayu) Xianning 437224Hubei ProvinceChina

With the rapid development of higher vocational education,the number of schools and enrollment has increased rapidly,and each specialty has been continuously *** has led to new challenges in the talent training of new specialties in higher vocational colleges in recent *** on the post ability standard of cost staff and the skill requirements of related posts,according to the characteristics of this major and guided by the idea of systematization of the work process,this paper discusses the problems existing in the talent training mode of higher vocational engineering cost major and provides some suggestions for the talent training and construction of higher vocational engineering cost *** aims to promote continuous teaching reform in the future and the development of engineering cost majors in higher vocational colleges.

关键词： Higher vocational college Engineering cost major Talent training mode

Current Situation and Countermeasures of the Construction of “Double-Qualified” Teachers in Higher Vocational Colleges

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Journal of Contemporary Educational Research 2024年第8期8卷 215-219页

作者： hong ye Yuan Zhong Yanping Chen Wuhan Technical College of Communications Wuhan 430065Hubei ProvinceChina Guanqiao Town Central Kindergarten(Jiayu) Xianning 437224Hubei ProvinceChina

The construction of“double-qualified”teachers is the basic premise for the high-quality development of higher vocational education,and it is also the key force for higher vocational colleges to cultivate high-quality skilled *** paper probes into the positioning of the construction of“double-qualified”teachers in higher vocational colleges,deeply analyzes the current situation of the construction of“double-qualified”teachers in higher vocational colleges,and provides the countermeasures of the construction of“double-qualified”teachers.

关键词： Higher vocational colleges “Double-qualified”teachers Current situation Countermeasure

三维耦合趋化—流体模型强解的全局存在性和衰减率估计

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数学进展 2024年第5期53卷 1019-1038页

作者：叶宏新疆财经大学统计与数据科学学院新疆乌鲁木齐830012

本文研究了三维全空间中耦合趋化一流体模型的初边值问题.在[***.,2020,105:106332,7 pp.]得出该模型Serrin型爆破准则的基础上,我们得出初值在L~3范数或H~(1/2)范数小时强解的全局存在性.作为解的全局存在性证明过程中所得估计的副产品... 详细信息

本文研究了三维全空间中耦合趋化一流体模型的初边值问题.在[***.,2020,105:106332,7 pp.]得出该模型Serrin型爆破准则的基础上,我们得出初值在L~3范数或H~(1/2)范数小时强解的全局存在性.作为解的全局存在性证明过程中所得估计的副产品,得出了强解的衰减率估计.

关键词：耦合趋化—流体模型强解全局存在性衰减率

Overexpression of low-density lipoprotein receptor prevents neurotoxic polarization of astrocytes via inhibiting NLRP3 inflammasome activation in experimental ischemic stroke

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Neural Regeneration Research 2025年第2期20卷 491-502页

作者： Shuai Feng Juanji Li Tingting Liu Shiqi Huang Xiangliang Chen Shen Liu Junshan Zhou hongdong Zhao ye hong Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Jinling HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina

Neurotoxic astrocytes are a promising therapeutic target for the attenuation of cerebral ischemia/reperfusion ***-density lipoprotein receptor,a classic cholesterol regulatory receptor,has been found to inhibit NLR family pyrin domain containing protein 3(NLRP3)inflammasome activation in neurons following ischemic stroke and to suppress the activation of microglia and astrocytes in individuals with Alzheimer’s ***,little is known about the effects of low-density lipoprotein receptor on astrocytic activation in ischemic *** address this issue in the present study,we examined the mechanisms by which low-density lipoprotein receptor regulates astrocytic polarization in ischemic stroke ***,we examined low-density lipoprotein receptor expression in astrocytes via immunofluorescence staining and western blotting *** observed significant downregulation of low-density lipoprotein receptor following middle cerebral artery occlusion reperfusion and oxygen-glucose deprivation/***,we induced the astrocyte-specific overexpression of low-density lipoprotein receptor using astrocyte-specific adeno-associated ***-density lipoprotein receptor overexpression in astrocytes improved neurological outcomes in middle cerebral artery occlusion mice and reversed neurotoxic astrocytes to create a neuroprotective ***,we found that the overexpression of low-density lipoprotein receptor inhibited NLRP3 inflammasome activation in oxygen-glucose deprivation/reoxygenation injured astrocytes and that the addition of nigericin,an NLRP3 agonist,restored the neurotoxic astrocyte *** findings suggest that low-density lipoprotein receptor could inhibit the NLRP3-meidiated neurotoxic polarization of astrocytes and that increasing low-density lipoprotein receptor in astrocytes might represent a novel strategy for treating cerebral ischemic stroke.

关键词： inflammation ischemia/reperfusion injury ischemic stroke low-density lipoprotein receptor neuroprotective astrocytes neurotoxic astrocytes NLRP3 inflammasome polarization