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梅尼埃病的影像学评估:球囊耳石可能是病因?

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临床耳鼻咽喉头颈外科杂志 2013年第15期27卷 839-843页

作者： HIDEO YAMANE KISHIKO SUNAMI HIROYOSHI IGUCHI hiramori sakamoto TOSHIO IMOTO HELGE RASK-ANDERSEN 张甦琳孔维佳 Department of Otorhinolaryngology Osaka City University Graduate School of MedicineOsakaJapan Department of Otorhinolaryngology Uppsala University HospitalUppsalaSweden 华中科技大学同济医学院附属协和医院耳鼻咽喉科武汉430022

目的:本研究拟采用3DCT来评估梅尼埃病(MD)患者的连合管(RD)、球囊管(SD)和内淋巴囊(ES)的显影情况。方法:根据美国耳鼻咽喉头颈外科学会听力与平衡委员会的诊断标准,我们采用3DCT对62例确诊为单侧MD的患者进行影像学评估,并与其对侧耳... 详细信息

目的:本研究拟采用3DCT来评估梅尼埃病(MD)患者的连合管(RD)、球囊管(SD)和内淋巴囊(ES)的显影情况。方法:根据美国耳鼻咽喉头颈外科学会听力与平衡委员会的诊断标准,我们采用3DCT对62例确诊为单侧MD的患者进行影像学评估,并与其对侧耳及正常对照组(26耳)进行比较,观察它们在3DCT影像中RD、SD和ES的通畅性。结果:MD患耳在3DCT影像中表现为连续性中断,与对照组比较差异有统计学意义(P<0.01)。结论:3DCT成像中,MD耳与对照耳相比,RD、SD和ES的显影明显减弱,提示内淋巴流动可能被致密物质阻断,该物质可能为球囊上脱落的耳石。RD、SD和ES可能参与MD的发病。

关键词：球囊管球囊内淋巴积水内淋巴管 CT成像双侧

New method of local adjuvant therapy with bicarbonate Ringer’s solution for tumoral calcinosis: A case report

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World Journal of Orthopedics 2024年第3期15卷 302-309页

作者： Takashi Noguchi Akio sakamoto Kensaku Kakehi Shuichi Matsuda Department of Orthopaedic Surgery Graduate School of MedicineKyoto UniversityKyoto 606-8507Japan

BACKGROUND Tumoral calcinosis is a condition characterized by deposits of calcium phosphate crystals in extra-articular soft tissues,occurring in hemodialysis *** phosphate crystals are mainly composed of hydroxyapatite,which is highly infilt-rative to tissues,thus making complete resection *** adjuvant method to remove or resolve the residual crystals during the operation is *** SUMMARY A bicarbonate Ringer’s solution with bicarbonate ions(28 mEq/L)was used as the *** resecting calcium phosphate deposits of tumoral calcinosis as much as possible,while filling with the solution,residual calcium phosphate deposits at the pseudocyst wall can be gently scraped by fingers or gauze in the operative field.A 49-year-old female undergoing hemodialysis for 15 years had swelling with calcium deposition for 2 years in the shoulders,bilateral hip joints,and the right foot.A shoulder lesion was resected,but the calcification remained and early re-deposition was *** the difficulty of a complete rection,we devised a bicarbonate dissolution method and excised the foot *** resection of the calcified material,the residual calcified material was washed away with bicarbonate Ringer’s *** The bicarbonate dissolution method is a new,simple,and effective treatment for tumoral calcinosis in hemodialysis patients.

关键词： Tumoral calcinosis Adjuvant therapy Bicarbonate Ringer’s solution Surgery Case report

Low skeletal muscle mass and high visceral adiposity are associated with recurrence of acute cholecystitis after conservative management:A propensity score-matched cohort study

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 64-70页

作者： Yudai Koya Michihiko Shibata Yuki Maruno Yoshitaka sakamoto Shinji Oe Koichiro Miyagawa Yuichi Honma Masaru Harada Department of Gastroenterology Kyushu Rosai HospitalMoji Medical Center3-1 HigashiminatomachiMoji-kuKitakyushu 801-8502Japan Third Department of Internal Medicine School of MedicineUniversity of Occupational and Environmental HealthKitakyushu 807-8555Japan Department of Surgery Kyushu Rosai Hospital Moji Medical CenterKitakyushu 801-8502Japan

Background:Recurrent acute cholecystitis(RAC)can occur after non-surgical treatment for acute cholecystitis(AC),and can be more severe in comparison to the first episode of *** skeletal muscle mass or adiposity have various effects in several *** aimed to clarify the relationship between RAC and body ***:Patients with AC who were treated at our hospital between January 2011 and March 2022 were *** psoas muscle mass and adipose tissue area at the third lumbar level were measured using computed tomography at the first episode of *** areas were divided by height to obtain the psoas muscle mass index(PMI)and subcutaneous/visceral adipose tissue index(SATI/VATI).According to median VATI,SATI and PMI values by sex,patients were divided into the high and low PMI *** performed propensity score matching to eliminate the baseline differences between the high PMI and low PMI groups and analyzed the cumulative incidence and predictors of ***:The entire cohort was divided into the high PMI(n=81)and low PMI(n=80)*** the propensity score-matched cohort there were 57 patients in each *** Kaplan-Meier analysis,the low PMI group and the high VATI group had a significantly higher cumulative incidence of RAC than their counterparts(log-rank P=0.001 and 0.015,respectively).In a multivariate Cox regression analysis,the hazard ratios of low PMI and low VATI for RAC were 5.250(95%confidence interval 1.083-25.450,P=0.039)and 0.158(95%confidence interval:0.026-0.937,P=0.042),***:Low skeletal muscle mass and high visceral adiposity were independent risk factors for RAC.

关键词： Acute cholecystitis Low skeletal muscle mass Recurrent acute cholecystitis Sarcopenia Visceral adiposity

Investigation of HO_(2) uptake mechanisms onto multiple-component ambient aerosols collected in summer and winter time in Yokohama,Japan

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Journal of Environmental Sciences 2024年第3期137卷 18-29页

作者： Jun Zhou Yukiko Fukusaki Kentaro Murano Tania Gautam Yu Bai Yoshimi Inomata Hiroaki Komatsu Mayuko Takeda Bin Yuan Min Shao Yosuke sakamoto Yoshizumi Kajii Institute for Environmental and Climate Research Jinan UniversityGuangzhou 511443China Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation forEnvironmental Quality Guangzhou 511443China Graduate School of Global Environmental Studies Kyoto UniversityKyoto606-8501Japan Yokohama Environmental Science Research Institute Yokohama Kanagawa 221–0024Japan Department of Chemistry University of AlbertaAlbertaEdmonton T6G 2G2Canada Graduate School of Human and Environmental Studies Kyoto UniversityKyoto 606-8501Japan Kanagawa Environmental Research Center Kanagawa 254-0014Japan Center for Regional Environmental Research National Institute for Environmental StudiesIbaraki305-8506Japan

The heterogeneous loss of HO_(2)radicals onto ambient aerosols plays an important role in tropospheric ***,sparse investigation of the dominating parameters controlling the HO_(2)uptake coefficients onto ambient aerosols(γHO_(2))has largely hindered the application of the measuredγHO_(2)to the global spatial *** we induced an offine method using LFP-LIF technique to measure the kinetics of HO_(2)uptake onto ambient aerosols collected in summertime and wintertime in Yokohama city,a regional urban site near Tokyo,*** controlling the dominating parameters which infuenceγHO_(2),we were able to investigate the detailed HO_(2)uptake *** characterized the chemical composition of the collected ambient aerosols,including organics,inorganics,transition metals ions,*** modeledγHO_(2)using different *** show thatγHO_(2)increased with the increase in RH,and the aerosol states(“dry”or wet/aqueous)have large effects onγHO_(2).With fixed RH and aerosol chemical composition,γHO_(2)was highly dependent on pH and inversely correlated with[HO_(2)]_*** combing the measuredγHO_(2)values with the modeled ones,we found that both the HO_(2)self-reaction and transition metal-catalyzed reactions should be accounted for to yield a single parameterization to predictγHO_(2),and different chemical compositions may have collective effects onγHO_(2).Results may serve for extending theγHO_(2)values measured at one observation site to different environmental conditions,which will help us to achieve more accurate modeling results concerning secondary pollutant formation(i.e.,ozone).

关键词： HO_(2)uptake kinetics Offine method Impacting factors Mechanism

Relationship between nutritional therapy and beneficial bacteria ratio in severe disease

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Journal of Acute Disease 2024年第1期13卷 26-30页

作者： Kento Nakayama Hiroyuki Koami Yuichiro sakamoto Advanced Emergency Care Center Saga University HospitalSaga 849-0851Japan

Objective:To evaluate relationship between changes in the beneficial bacteria in intensive care unit(ICU)patients and nutritional therapy ***:Ten patients aged≥18 years admitted to the ICU between January and December 2020,were *** enteral nutrition was defined as early achievement of target calorie intake through enteral *** ratio of beneficial bacteria at the first and second bowel movements after each patient’s admission was calculated and the patients were classified into the increase or decrease *** all patients,five each were in the increase and decrease *** investigated patient background,changes in sequential organ failure assessment(SOFA)and acute physiology and chronic health evaluation(APACHE)Ⅱscores,nutritional doses or methods,and clinical ***:No relationship was found between changes in the ratio of beneficial bacteria and changes in SOFA/APACHEⅡscores at the time of *** rate of good enteral nutrition was significantly higher in the increase group than in the decrease group(4/5 vs.0/5,P=0.01).Conclusions:An increase in beneficial bacteria may be significantly related to the early establishment of enteral *** the future,accumulating cases may make it possible to establish a new nutritional strategy for critically ill patients from an intestinal microbiota perspective.

关键词： Beneficial bacteria Enteral nutrition Parenteral nutrition Intensive care unit Good enteral nutrition Severe disease Nutritional therapy

Hand Cooling Enhances the Proprioceptive Drift during Rubber Hand Illusion

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Journal of Behavioral and Brain Science 2024年第7期14卷 210-226页

作者： Masanori sakamoto Yuta Akaike Kazuya Tatsumi Hirotoshi Ifuku Division of Health and Physical Education Graduate School of Education Kumamoto University Kumamoto City Japan Lifelong Sports and Welfare Course Faculty of Education Kumamoto University Kumamoto City Japan

Background: The neural representation of the body is easily altered by integrating multiple sensory signals in the brain. The “Rubber Hand Illusion” (RHI) is one of the most popular experimental paradigms to investigate this phenomenon. During this illusion, ownership of a rubber hand is temporarily induced. It was shown that external and continuous cooling of the palm enhanced the RHI, suggesting an association between altered the autonomic nervous system regulation and altered the sense of ownership of a specific limb. Purpose: To investigate whether artificially cooling the entire hand for a short period affects the magnitude of the illusion. Methods: Participants immersed their entire hand in cool, cold, or warm water for 1 min before the RHI procedure. Results: We found that cooling the entire hand enhanced the proprioceptive drift during the RHI but not the subjective feeling of ownership. In contrast, warming and intense cooling of the entire hand did not affect the RHI strength. Conclusion: Our results suggest that transient and moderate cooling of the entire hand was sufficient in enhancing the illusory disembodiment of one’s own hand.

关键词： Hand Temperature Cooling Rubber Hand Illusion Ownership Proprioceptive Drift

Porphyrin/Fullerene Porous Molecular Cocrystal Featuring a Robust One-Dimensional Channel

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Precision Chemistry 2024年第9期2卷 480-487页

作者： Nobuhiro Sato Ryojun Toyoda Tetsu Sato Zi Lang Goo Shinya Takaishi Koki Chida Takeharu Yoshii Hirotomo Nishihara Kunihisa Sugimoto Ryota sakamoto Department of Chemistry Graduate School of ScienceTohoku UniversitySendai 980-8578Japan Department of Chemistry Kindai UniversityOsaka 577-8502Japan Institute of Multidisciplinary Research for Advanced Materials Tohoku UniversitySendaiMiyagi 980-8577Japan Institute of Multidisciplinary Research for Advanced Materials and Advanced Institute for Materials Research(WPI-AIMR) Tohoku UniversitySendaiMiyagi 980-8577Japan Division for the Establishment of Frontier Sciences of Organization for Advanced Studies Tohoku UniversitySendai 980-8577Japan

Microporous molecular crystals are promising materials because of their designable porosity as well as their resistance to chemical and other ***,we developed microporous molecular cocrystals by taking advantage of the specific interactions between porphyrins and fullerene ***-crystal X-ray diffraction analysis revealed that one nickel(II)porphyrin interacts with two fullerene molecules to form a two-dimensional honeycomb network with an eclipsed stacking mode,providing onedimensional void *** the pores were activated by heat treatment or mechanical grinding,the prepared cocrystal can incorporate gas and solvent molecules reversibly while maintaining its ***,it retained its single-crystallinity in the presence of water,acid−base,or high *** findings in this study expand the availability of molecular crystals based on intermolecular interactions as porous materials,which are expected to work under conditions that have not been applicable to other molecule-based porous materials.

关键词： Microporous molecular crystal intermolecular interaction gas adsorption chemical stability high-pressure resistance

Corroborative Activities and Recognition Between Community Comprehensive Care Unit’s Nurses and Care Managers in Supporting Discharge of Elderly from Hospital - A Secondary Publication

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Journal of Clinical and Nursing Research 2024年第4期8卷 381-392页

作者： Yukie sakamoto Shizuko Omote Rie Okamoto Yutaro Takahashi Satomi Ikeuchi Division of Health Sciences Graduate School of Medical SciencesKanazawa UniversityKanazawa 920-0934Japan Kanazawa City Community Comprehensive Support Center Tobiume Kanazawa 920-0938Japan Faculty of Health Sciences Institute of MedicalPharmaceutical and Health SciencesKanazawa UniversityKanazawa 920-1192Japan

Objective: The purpose of this study was to clarify the collaborative activities and mutual recognition between community comprehensive care unit nurses (Ns) and care managers (CM) in supporting the discharge of the elderly from the hospital. Methods: A total of 300 nurses working in community comprehensive care wards and 360 care managers working in B City in A Prefecture were surveyed using an anonymous self-administered questionnaire. Results: The highest percentage of responses regarding necessary collaborative activities with multiple professions in supporting hospital discharge were the same for Ns and CMs. The items regarding practice with the highest percentages were “relationship as a team” for Ns, and “user-centered awareness” for CM. While these professionals were willing to share information about their patients’ lives after discharge, the percentage of those explaining their expertise was low. It is thought that collaborative activities focusing on these aspects would lead to more appropriate discharge support.

关键词： Discharge support Community comprehensive care ward Ward nurses Care managers Collaborative activities

Adult-Type Granulosa Cell Tumor with Similar Clinical Findings Seen during Ovarian Cystectomy Performed at the Same Time as Laparoscopic Ovarian Drilling for Polycystic Ovarian Syndrome: An Extremely Rare Case

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Open Journal of Obstetrics and Gynecology 2024年第8期14卷 1197-1206页

作者： Remi Nakajima Risa Kobayashi Marie Kawai Eriko sakamoto Miho Matsuda Rieko Kanda Makoto Kawamura Department of Obstetrics and Gynecology Kohseichuo General Hospital. Tokyo Japan

Polycystic ovary syndrome (PCOS) is a major cause of anovulatory infertility. Laparoscopic ovarian drilling (LOD) is a treatment for PCOS that allows the laparoscopic identification of other intra-abdominal lesions and the provision of diagnostic treatment. This study reports a case of PCOS with an ovarian mass in which LOD was aggressively used and a granulosa cell tumor (GCT) was found. A 34-year-old woman with secondary amenorrhea and irregular menstrual cycles presented to the emergency department with abdominal pain of unknown etiology. Imaging studies revealed a 6-cm left ovarian mass with an internal appearance suggestive of a hemorrhage. The patient’s secondary amenorrhea was subsequently diagnosed as PCOS, and LOD was performed to preserve her fertility. Simultaneously, a cystectomy was performed to evaluate the tumor in the left ovary;the diagnosis was adult-type GCT. Although concomitant GCT and PCOS are extremely rare, the two conditions have similar clinical manifestations. In women of reproductive age, the impact of surgery on future fertility should be considered, and the initial surgical technique should be chosen carefully.

关键词： Polycystic Ovary Syndrome Laparoscopic Ovarian Drilling Granulosa Cell Tumor