检索结果-南通市图书馆

Chinese Medical Journal 2006年第11期119卷 939-943页

作者： hei zi-qing liu de-zhao luo chen-fang li shang-rong ma wu-hua luo gang-jian department of Anesthesiology Third Affiliated Hospital SunYat-sen University Guangzhou 510630 China

Patients undergoing orthotopic liver transplantation may develop significant haemodynamic instability, especially during anhepatic phase and immediately after reperfusion of the graft. The haemodynamic instability may be caused directly by myocardial depression due to pathogenic substances released from the liver, or by acute blood loss.^1 Creatine kinase（CK） and its MB fraction （CK-MB） are sensitive and specific indicators to reflect myocardial damage.^2 Cardiac troponin I （cTnl） is a specific and sensitive marker of myocardial necrosis.^3 This study assessed perioperative cardiac function using three indicators （CK,CK-MB,and CTnl） to evaluate perioperative myocardial damage.

关键词： ventricular function orthotopic liver transplantation creatine kinase cardiac troponin I

原位肝移植术围术期血流动力学变化与心肌损害的关系

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中国临床康复 2005年第42期9卷 53-55页

作者：刘德昭黑子清罗刚健黎尚荣马武华罗晨芳中山大学第三附属医院麻醉科广东省广州市510630

目的:观察肝移植围术期血流动力学以及各种心肌酶的变化,探讨血流动力学变化与心肌损害的关系。方法:选取2004-06/09中山大学第三附属医院拟行原位肝移植术的终末期肝病患者20例,静吸复合全身麻醉下接受原位肝移植术。常规结扎切断肝管... 详细信息

目的:观察肝移植围术期血流动力学以及各种心肌酶的变化,探讨血流动力学变化与心肌损害的关系。方法:选取2004-06/09中山大学第三附属医院拟行原位肝移植术的终末期肝病患者20例,静吸复合全身麻醉下接受原位肝移植术。常规结扎切断肝管、肝左右动脉和门静脉,用肝上下腔静脉阻断钳从前至后夹闭肝上下腔静脉,切除病肝后进行供肝吻合。先吻合腔静脉,腔静脉吻合口为倒三角形,再吻合门静脉,恢复供肝血流,进入新肝期,再依次吻合肝动脉和胆管。分别在术前、无肝前、无肝期30min、新肝期30m in、术毕、术后24h各采中心静脉血3m L,测定心肌酶谱。同时测量围术期心率、心输出量、中心静脉压、平均动脉压。结果:按意向处理分析,实验纳入患者20例,全部进入结果分析。①全部患者术后转归情况:20例患者均成功接受原位肝移植术。手术时间(335.74±74.04)min,无肝期时间(36.37±7.90)m in。术后3例出现心脏衰竭,心脏衰竭患者中有2例最终死亡。其余患者术后均恢复良好。②全部患者肝移植围术期血流动力学的变化:心输出量和中心静脉压在无肝期下降(P0.05);新肝期30m in、术毕的心肌酶谱各值均显著增高(P0.05),其余各种酶均显著增高(P0.05)。结论:新肝期表现为高血流动力学,而心肌酶普遍增高,术后24h开始恢复,提示开放后血流动力学与心肌损害存在分离现象。

关键词：肝移植心肌/酶学血液动力学心肌/病理学

肝移植围术期血浆一氧化氮和一氧化氮合酶活性的变化及意义

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中国病理生理杂志 2005年第11期21卷 2229-2232页

作者：罗晨芳黑子清罗刚健黎尚荣马武华刘德昭付咏梅中山大学附属第三医院麻醉科广东广州510630 暨南大学医学院病理生理教研室广东广州510632

目的动态观察肝移植围术期血浆一氧化氮(NO)水平和一氧化氮合酶(NOS)活性的变化,并探讨其意义。方法30例终末期肝病患者接受原位肝移植术。用放免法、比色法分别测定肝移植围术期5个时点血浆NO2-/NO3-水平和NOS活性,观察其动态变化。同... 详细信息

目的动态观察肝移植围术期血浆一氧化氮(NO)水平和一氧化氮合酶(NOS)活性的变化,并探讨其意义。方法30例终末期肝病患者接受原位肝移植术。用放免法、比色法分别测定肝移植围术期5个时点血浆NO2-/NO3-水平和NOS活性,观察其动态变化。同步抽取桡动脉和肺动脉血做血气分析,记录不同时期的PO2、PCO2、SO2、Hb,根据肺内分流标准模型公式计算(Qs/Qt)。并监测围术期心输出量(CO)、心率(HR)、中心静脉压(CVP)、平均动脉压(maBP)、体循环阻力(SVR)。结果(1)无肝前10min NO2-/NO3-水平明显高于麻醉后术前。无肝期30min NO2-/NO3-显著低于无肝前10min。新肝期30min NO2-/NO3-显著高于麻醉后术前、无肝期30min。(2)TNOS活性各时点无显著差异。无肝前10min、新肝30min时iNOS活性明显高于麻醉后术前。与无肝30min值比较,新肝期30miniNOS活性显著升高。(3)maBP在开放下腔静脉后1min明显下降,CO和CVP在无肝期下降,新肝期增高。SVR在无肝期增高,新肝期明显下降。(4)Qs/Qt在无肝期下降,新肝期30min升高。结论在肝移植围术期各个时段,NO水平及iNOS活性各不相同。高NO水平可能是新肝期低阻力、肺内分流增加的原因。

关键词：肝移植一氧化氮一氧化氮合酶血流动力学

原位肝移植围术期混合静脉血氧饱和度改变及临床意义

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中国危重病急救医学 2006年第7期18卷 391-393页

作者：刘德昭黑子清陈信芝罗晨芳甘小亮黎尚荣罗刚健中山大学第三附属医院麻醉科广州510630

目的观察原位肝移植围术期混合静脉血氧饱和度(SvO2)的变化及其临床意义。方法20例终末期肝硬化患者接受原位肝移植术。采用心排仪持续监测围术期SvO2、氧供(DO2)、氧耗(VO2)、氧摄取率(ERO2)、体温、心排血量(CO)、平均动脉压(maP)的变... 详细信息

目的观察原位肝移植围术期混合静脉血氧饱和度(SvO2)的变化及其临床意义。方法20例终末期肝硬化患者接受原位肝移植术。采用心排仪持续监测围术期SvO2、氧供(DO2)、氧耗(VO2)、氧摄取率(ERO2)、体温、心排血量(CO)、平均动脉压(maP)的变化,分析肝移植围术期SvO2与上述各指标的相关性。结果SvO2在无肝期前15min较术前增高(P0.05);SvO2术前与CO有显著相关性(P0.05)。结论原位肝移植围术期持续监测SvO2对于改善氧代谢具有重要的临床意义。

关键词：肝移植原位混合静脉血氧饱和度氧供氧耗心排血量血流动力学血氧代谢

Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin liu Yue huang Guang-cheng Xiao qing-Cui Bu Jin-Lu Qu Shu Zhang Shuang-Nan Zhang Shu-Mei Jia fang-Jun Lu Xiang ma lian Tao Wei Zhang li chen li-Ming Song Ti-Pei li Yu-Peng Xu Xue-Lei Cao Yong chen Cong-Zhan liu Ce Cai Zhi Chang gang chen Tian-Xiang chen Yi-Bao chen Yu-Peng chen Wei Cui Wei-Wei Cui Jing-Kang deng Yong-Wei Dong Yuan-Yuan Du Min-Xue Fu Guan-hua Gao He Gao Min Gao Ming-Yu Ge Yu-Dong Gu Ju Guan cheng-cheng Guo Da-Wei Han Jia Huo Lu-hua jiang Wei-Chun jiang Jing Jin Yong-Jie Jin ling-Da Kong Bing li cheng-Kui li gang li mao-Shun li Wei li Xian li Xiao-Bo li Xu-fang li Yang-Guo li Zheng-Wei li Xiao-hua liang Jing-Yuan liao Bai-Sheng liu Guo-qing liu Hong-Wei liu Xiao-Jing liu Yi-Nong liu Bo Lu Xue-Feng Lu Qi luo Tao luo Bin Meng Yi Nang jian-Yin Nie Ge Ou Na Sai Ren-cheng shang Xin-Ying Song liang Sun Ying Tan You-li Tuo chen Wang Guo-Feng Wang Juan Wang ling-Jun Wang Weng-Shuai Wang Yu-Sa Wang Xiang-Yang Wen Bai-Yang wu Bo-Bing wu Mei wu Shuo Xiao Shao-lin Xiong He Xu Jia-Wei Yang Sheng Yang Yan-Ji Yang Yi-Jung Yang Qi-Bin Yi Qian-qing Yin Yuan You Ai-Mei Zhang cheng-Mo Zhang Fan Zhang Hong-Mei Zhang Juan Zhang Tong Zhang Wan-Chang Zhang Wen-zhao Zhang Yi Zhang Yi-Fei Zhang Yong-Jie Zhang Yuan-Hang Zhang Yue Zhang zhao Zhang Zhi Zhang zi-liang Zhang Hai-Sheng zhao Xiao-Fan zhao Shi-Jie Zheng Yao-Guang Zheng deng-Ke Zhou jian-Feng Zhou Yu-Xuan Zhu Ren-lin Zhuang Yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany department of Astronomy Beijing Normal UniversityBeijing 100088China department of Astronomy Tsinghua UniversityBeijing 100084China department of Physics Tsinghua UniversityBeijing 100084China department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline(updated version)

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Military Medical Research 2020年第3期7卷 249-282页

作者： Ying-Hui Jin qing-Yuan Zhan Zhi-Yong Peng Xue-Qun Ren Xun-Tao Yin lin Cai Yu-Feng Yuan Ji-rong Yue Xiao-Chun Zhang Qi-Wen Yang jianguang Ji jian Xia Yi-rong li Fu-Xiang Zhou Ya-Dong Gao Zhui Yu Feng Xu Ming-li Tu li-Ming Tan Min Yang fang chen Xiao-Ju Zhang Mei Zeng Yu Zhu Xin-Can liu jian Yang Dong-Chi zhao Yu-Feng Ding Ning Hou Fu-Bing Wang Hao chen Yong-gang Zhang Wei li Wen chen Yue-Xian Shi Xiu-Zhi Yang Xue-Jun Wang Yan-Jun Zhong Ming-Juan zhao Bing-Hui li lin-Lu ma Hao zi Na Wang Yun-Yun Wang Shao-Fu Yu Lu-Yao li Qiao huang Hong Weng Xiang-Ying Ren li-Sha luo man-Ru Fan Di huang Hong-Yang Xue lin-Xin Yu Jin-Ping Gao Tong deng Xian-Tao Zeng Hong-Jun li Zhen-Shun cheng Xiao-Mei Yao Xing-huan Wang Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Respiratory Diseases China-Japan Friendship HospitalBeijing 100029China department of Pulmonary and Critical Care Medicine China-Japan Friendship HospitalBeijing 10029China Leishenshan Hospital in wuhan Wuhan 430200China department of Critical Care Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Institutes of Evidence-based Medicine and Knowledge Translation Henan UniversityKaifeng 475000HenanChina department of Medical Imaging Guizhou Provincial People’s HospitalGuiyang 550002China departments of Orthopedics Zhongnan Hospital of Wuhan UniversityWuhan 430071China department of Hepatobiliary Surgery Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China department of Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China department of Radiology Zhongnan Hospital of Wuhan UniversityWuhan 430071China department of Clinical Laboratory Peking Union Medical College Hospital(PUMCH)Peking Union Medical CollegeChinese Academy of Medical Sciences(CAMS)Beijing 100730China Center for Primary Health Care Research Lund University and Region Skåne25002 MalmöSweden Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 403371China department of Allergology Zhongnan Hospital of Wuhan UniversityWuhan 430071China department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhan 43071China department of Critical Care Medicine Renmin Hospital of Wuhan UniversityWuhan 430060China department of Emergency Medicine and Chest Pain Center Qilu Hospital of Shandong UniversityJinan 250002China department of Respiratory and Critical Care Medicine Suizhou Central HospitalHubei University of MedicineSuizhou 441300HubeiChina department of Clinic Pharmacy Second People’s Hospital of Huaihua Ci

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the cause of a rapidly spreading illness,coronavirus disease 2019(COVID-19),affecting more than seventeen million people around the *** and treatment guidelines for clinicians caring for patients are *** the early stage,we have issued"A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV)infected pneumonia(standard version)";now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based *** formed a working group of clinical experts and *** steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas:chemoprophylaxis,diagnosis,treatments,and discharge *** searched the literature for direct evidence on the management of COVID-19,and assessed its certainty generated recommendations using the Grading of Recommendations,Assessment,development and Evaluation(GRAde)*** were either strong or weak,or in the form of ungraded consensus-based ***,we issued 34 *** them,6 were strong recommendations for,14 were weak recommendations for,3 were weak recommendations against and 11 were ungraded consensus-based *** covered topics of chemoprophylaxis(including agents and Traditional Chinese Medicine(TCM)agents),diagnosis(including clinical manifestations,reverse transcription-polymerase chain reaction(RT-PCR),respiratory tract specimens,IgM and IgG antibody tests,chest computed tomography,chest X-ray,and CT features of asymptomatic infections),treatments(including lopinavirritonavir,umifenovir,favipiravir,interferon,remdesivir,combination of antiviral drugs,hydroxychloroquine/chloroquine,interleukin-6 inhibitors,interleukin-1 inhibitors,glucocorticoid,qingfei paidu decoction,lianhua qingwen granules/capsules,convalescent plasma,lung

关键词： COVID-19 SARS-CoV-2 Recommendation Chemoprophylaxis Diagnosis Treatment Discharge management Traditional Chinese medicine guideline

Sex differences in the scored Patient-Generated Subjective Global Assessment in 19,528 cancer patients

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Journal of Nutritional Oncology 2023年第1期8卷 38-46页

作者： Wang Yan-li wu Tian-Tian Fu Zhen-Ming Guo Zeng-qing lin Yuan Shi Ying-Ying Hu Wen Ba Yi li Su-Yi li Zeng-Ning Wang Kun-hua wu Jing He Ying Yang Jia-Jun Xie Cong-hua Zhou Fu-Xiang Song Xin-Xia chen Gong-Yan ma Wen-Jun luo Su-Xia chen zi-hua Cong Ming-hua ma Hu Zhou Chun-ling Wang Wei luo Qi Shi Yong-Mei Qi Yu-Mei jiang Hai-Ping Guan Wen-Xian chen Jun-Qiang chen Jia-Xin fang Yu Zhou Lan Feng Yong-Dong Tan rong-Shao li Tao Ou Jun-Wen zhao qing-Chuan wu jian-Xiong lin Xin Yang liu-qing Zhang Qi Jia Ping-Ping li Wei Xu Hong-Xia Shi Han-Ping Song Chun-hua The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group Chinese Society of Nutritional Oncology department of Epidemiology and Statistics College of Public HealthZhengzhou UniversityZhengzhouHenanChina Cancer Center Renmin Hospital of Wuhan UniversityWuhanHubeiChina department of Medical Oncology Fujian Cancer HospitalFujian Medical University Cancer HospitalFuzhouFujianChina department of Gastrointestinal Surgery Affiliated Tumor Hospital of Guangxi Medical UniversityNanningGuangxiChina department of Surgery The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongChina department of Clinical Nutrition West China Hospital of Sichuan UniversityChengduSichuanChina department of Gastrointestinal Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin Key Laboratory of Cancer Prevention and TherapyTianjinChina department of Nutrition and Metabolism of Oncology Affiliated Provincial Hospital of Anhui Medical UniversityHefeiAnhuiChina department of Clinical Nutrition The First Hospital of Hebei Medical UniversityShijiazhuangHebeiChina department of Gastrointestinal Surgery Institute of GastroenterologyThe First Affiliated Hospital of Kunming Medical UniversityKunmingYunnanChina Zhongshan chenxinghai Hospital(Affiliated Zhongshan chenxinghai Hospital of Guangdong Medical University) ZhongshanGuangdongChina department of Clinical Nutrition The First People's Hospital of KashiKashiXinjiangChina department of Clinical Nutrition Chongqing General HospitalChongqingChina department of Colorectal and Anal Surgery Huizhou Municipal Central HospitalHuizhouGuangdongChina department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhanHubeiChina department of Oncology Xingtai People’s HospitalHebei Medical UniversityXingtaiHebeiChina The First department of the Tumor Hospital of Harbin Medical University HarbinHeilongjiangChina department of Nutrition Guangdong General HospitalGuangdong Academy of Medical SciencesGuangzhouGuangdongChina department of Oncology Affiliated

Background:The scored Patient-Generated Subjective Global Assessment(PG-SGA)has been widely used to assess the nutritional status of cancer *** purpose of this study is to compare the differences in PG-SGA scores and the 7 domain scores of the PG-SGA in male and female cancer ***:This study was conducted at 72 hospitals from July 2013 to december 2018,a part of the Investigation on Nutritional Status and its Clinical Outcomes of Common *** PG-SGA was recorded to evaluate the nutritional status of patients.A total of 19,528 patients with 13 common malignancies were included in this *** t test and the χ^(2) test were applied to analyze the sex diferences in the 7 domain *** Cancer Genome Atlas(TCGA)database was used to analyze the expression levels of symptom-related ***:There were significant sex dfferences in the PG-SGA(P=0.032),notably in patients with gastric cancer(male vs female:9.09±4.86 vs 9.58±5.07,P=0.005)and esophageal cancer(9.64±4.90 vs 10.46±4.96,P=0.011)and the average total PG-SGA of female patients was slightly higher than that of male patients(7.64±4.98 vs 7.77±5.14).The differences were mainly related to the weight,eating,symptom,as well as activity and physical function scores in the stratified *** causes of the sex differences were the rates of nausea,vomiting,dry mouth,and other symptoms,in both gastric and esophageal cancer *** of the TCGA database suggested that most of the related genes were sex neutral,except for genes related to dysphagia in gastric cancer(VEGFC was higher in female patients,VEGFA and VEGFB higher in male patients).Conclusions:There are sex differences in the PG-SGA scores in patients with various tumor types(female patients generally had higher scores than male patients),with differences mainly in the weight,eating,symptom,as well as activity and physical function *** sex differences in PG-SGA scores might be due to the differences i

关键词： PG-SGA Sex differences malnutrition Cancer patients TCGA database

Extension Protocol for the Investigation on Nutrition Status and Clinical Outcome of Patients with Common Cancers in China(INSCOC)Study:2021 update

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Journal of Nutritional Oncology 2022年第2期7卷 64-74页

作者： Hong Xia Xu Chun hua Song liang Yu Yin Chang Wang Zhen Ming Fu Zeng qing Guo Yuan lin Ying Ying Shi Wen Hu Yi Ba Su Yi li Zeng Ning li Kun hua Wang Jing wu Ying He Jia Jun Yang Cong hua Xie Fu Xiang Zhou Xin Xia Song Gong Yan chen Wen Jun ma Su Xia luo zi hua chen Zhi Kang chen Ming hua Cong Hu ma Chun ling Zhou Wei Wang Qi luo Yong Mei Shi Yu Mei Qi Hai Ping jiang Wen Xian Guan Jun Qiang chen Xiang hua wu Jia Xin chen Yu fang Lan Zhou Yong Dong Feng rong Shao Tan Tao li Jun Wen Ou qing Chuan zhao jian Xiong wu Min Weng qing hua Yao Ya Yin Yu Quan Jun Lyu Hong Qiu Ming liu Wei li Han Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group department of Nutrition Daping HospitalArmy Medical University(Third Military Medical University)Chongqing 400042China department of Epidemiology College of Public HealthZhengzhou UniversityZhengzhou 450001HenanChina Cancer Center of the First Hospital of Jilin University Changchun 130021Jilin China Cancer Center Renmin Hospital of Wuhan UniversityWuhan 430060HubeiChina department of Medical Oncology Fujian Cancer HospitalFujian Medical University Cancer HospitalFuzhou 350014FujianChina department of Gastrointestinal Surgery Affiliated Tumor Hospital of Guangxi Medical UniversityNanning 530021GuangxiChina department of Surgery The First Affiliated Hospital of SunYat-Sen UniversityGuangzhou 510080GuangdongChina department of Clinical Nutrition West China Hospital of Sichuan UniversityChengdu 610041SichuanChina department of Gastrointestinal Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin Key Laboratory of Cancer Prevention and TherapyTianjin 300060China department of Nutrition and Metabolism of Oncology The First Affiliated Hospital of University of Science and Technology of ChinaAnhui Provincial Cancer HospitalHefei 230031AnhuiChina department of Clinical Nutrition The First Hospital of Hebei Medical UniversityShijiazhuang 050031HebeiChina department of Gastrointestinal Surgery Institute of GastroenterologyThe First Affiliated Hospital of Kunming Medical UniversityKunming 650032YunnanChina department of Clinical Nutrition The First Affiliated Hospital of Zhejiang Chinese Medical UniversityZhejiang Provincial Hospital of Traditional Chinese MedicineHangzhou 310006ZhejiangChina department of Clinical Nutrition Chongqing General HospitalChongqing 400014China department of Colorectal and Anal Surgery Huizhou Municipal Central HospitalHuizhou 516001GuangdongChina department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina department of Oncology Xingtai Peo

Background malnutrition is common in patients with cancer,and this adversely affects the survival and quality of life of *** Society for Nutritional Oncology issued a multi-center,large-scale,long-term follow-up prospective study,the Investigation on Nutrition Status and Clinical Outcome of Patients with Common Cancers in China(INSCOC study)since *** is an extension to the previous 2013-2020 study *** study still sought to:①address the prognostic impact of nutritional factors and quality of life on cancer patient survival;②describe the overall and cancer-specific incidence and/or distribution of malnutrition and different measurements of patient quality of *** and study design This is an observational,multi-centered,hospital-based prospective cohort *** collection will be performed at baseline(within 48 hours after patient admission),during the hospital stay and 30 days after hospital ***-up will be conducted for 1-20 years after *** primary outcome will be the all-cause mortality/overall survival,and secondary outcomes will be the length of hospital stay and costs of *** factors will include demographic characteristics,tumor characteristics,information about chronic diseases,hematological measurements(e.g.,red blood cell count,total lymphocyte counts,hemoglobin,albumin,prealbumin,creatinine,C-reactive protein,IL-6),anthropometric measurements(e.g.,height,weight,arm circumference,arm muscle circumference,triceps skinfold thickness,and waist circumference),body composition parameters,PG-SGA scores,quality of life(as indicated by the QLQ-C30 questionnaire),muscle mass(as indicated by the calf circumference),muscle strength(as indicated by the handgrip strength),muscle function(as indicated by the six-meter walking speed test)and physical status assessments(as indicated by the Karnofsky Performance Status scores).This clinical study protocol was approved by local Ethics Committees of

关键词： Cancer malnutrition Nutritional status Nutritional assessment Survival Patient-Generated Subjective Global Assessment

Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song chen Yan-Fen Chai Xiao-Hui chen Yu-Guo chen Shao-Wen cheng Wen-Wei cheng Bang-Han Ding Yang deng Jie Fu Bang-jiang fang mai-Ying Fan li Gui Ping Gong Wei Guo Shu-Bin Guo liang huang Ji-Yuan Han Zhong Ji Xian-Fei Ji Xin-Cai Ji Hong-Xu Jin Xin-Jun jiang Wang-Xiang jiang Jia-liang liu Xiao-Ran liu Zhi liu Chuan-Zhu Lv Feng Lu Tan-Shi li Xin li Yong li shang-Lun li Shuang-Ming li Xiao-gang li Bao-Jun li Pei-wu li Chun-Sheng li Zhi-Jun li Chang-luo li Xiang-Min li Yin-Ping li Zong-Jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-Qian luo Xiao-Xing liao jian-Bo Lei Tao ma Yu ma Yue-Feng ma qing-Bian ma lin-Hao ma Jun-Qi ma Shi-Nan Nie Jie-Miao Ou-Yang Peng Peng Qiao Pei Shu-Ming Pan Guo-Zhong qing li-Jie Qin wu-Ying Qiao Fei Shao Wei Song Xing-Yue Song Zhen-Ju Song rong-Ju Sun de-Ya shang Du-Juan Sha Gui-Lan Tao Guo-gang Tian Ying-Ping Tian jian-Guang Tian Chao-Yang Tong zi-Ren Tang Meng-Xiong Tang Guo-Ping wu Zhi Wan Tao Wang Xin Wang Peng Wang Zhong Wang Tong Wang Ri-Xing Wang Yi-Xin Wang Xiao-Dan Wang ling wu Wei Wei hua Xiang Feng Xu Jun Xu Jie Xu Miao-rong Xie Shuo-Gui Xu Tie Xu Feng Yu Wen Yi li-Shan Yang Shi-Jiao Yan Jin-jian Yao Shou-Chun Yan Xue-Zhong Yu Xian-Zhi Ye Xian-liang Yan Fu-Bing Zhou rong-Bin Zhou Ming Zhou Qiang Zhou Jin Zhou Ping Zhou Chang-Ju Zhu hua-Dong Zhu Ji-Hong Zhu Hong Zhang mao Zhang hua Zhang Na Zhang Guo-Qiang Zhang Guo-Xiu Zhang Jin-Song Zhang Wen-wu Zhang Wen-Zhong Zhang jian-Feng Zhang Yi-Min Zhu Jun Zeng Yuan Zheng Zhi-Jie Zheng Shen zhao Yan zhao Min zhao Bin zhao Xiao-Dong zhao Xiao-Jing zhao Hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

新型冠状病毒肺炎药物预防、诊断、治疗与出院管理循证临床实践指南(更新版)

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解放军医学杂志 2020年第10期45卷 1003-1031页

作者：靳英辉詹庆元彭志勇任学群尹训涛蔡林袁玉峰岳冀蓉张笑春杨启文纪建光夏剑李一荣周福祥高亚东余追徐峰涂明利谭力铭杨旻陈芳张晓菊曾玫朱渝刘新灿杨简赵东赤丁玉峰侯宁汪付兵陈昊张永刚李玮陈文施月仙杨秀芝王学军钟燕军赵明娟李柄辉马琳璐訾豪王娜王云云余绍福李路遥黄桥翁鸿任相颖罗丽莎范曼如黄笛薛竑飏余临心高锦萍邓通曾宪涛李宏军程真顺姚晓梅王行环无武汉大学中南医院循证与转化医学中心武汉430071 中日友好医院国家呼吸系统疾病临床研究中心北京100029 中日友好医院呼吸与危重症医学科北京100029 武汉雷神山医院武汉430200 武汉大学中南医院重症医学科武汉430071 河南大学循证医学与临床转化研究院河南开封475000 贵州省人民医院医学影像科贵阳550002 武汉大学中南医院骨科武汉430071 武汉大学中南医院肝胆外科武汉430071 四川大学华西医院国家老年疾病临床医学研究中心成都610041 四川大学华西医院老年医学中心成都610041 武汉大学中南医院医学影像中心武汉430071 中国医学科学院/北京协和医学院检验学系北京协和医院检验科北京100730 瑞典隆德大学临床研究中心/斯科讷大学医院马尔默25002 武汉大学中南医院急救中心武汉403371 武汉大学中南医院过敏反应科武汉403371 武汉大学中南医院肿瘤放化疗科武汉403371 武汉大学人民医院重症医学科武汉430060 山东大学齐鲁医院急诊科与胸痛中心济南250002 湖北医药学院附属随州市中心医院呼吸与重症医学科湖北随州441300 湖南省怀化市第二人民医院药学部湖南怀化418000 安徽医科大学第二附属医院重症医学科合肥230601 郑州大学医院内科郑州450001 河南省人民医院呼吸与危重症医学科郑州450003 复旦大学附属儿科医院感染传染科上海201102 四川大学华西第二医院感染科成都610041 河南中医药大学第一附属医院心内科郑州450000 三峡大学人民医院/宜昌市第一人民医院心内科湖北宜昌443000 武汉大学中南医院儿科武汉430071 华中科技大学同济医学院附属同济医院药学部武汉430030 山东第一医科大学附属省立医院/山东省立医院药学部济南250021 南京中医药大学教育部针药结合重点实验室南京210023 四川大学华西医院华西期刊社成都610041 青岛大学附属烟台毓璜顶医院检验医学中心山东烟台264000 十堰市太和医院(湖北医药学院附属医院)医学影像中心湖北十堰442000 北京大学护理学院北京100191 开封市中心医院呼吸与危重症医学科河南开封475000 北京电力医院急诊科北京100073 中南大学湘雅二医院重症医学科长沙410008 武汉大学中南医院泌尿科武汉430071 武汉大学中南医院血液科武汉430071 河南大学医学院护理与健康学院河南开封475000 山西医科大学护理学院太原030001 首都医科大学北京佑安医院放射诊断科北京100069 武汉大学中南医院呼吸与危重症医学科武汉430071 麦克马斯特大学卫生研究方法证据及影响系安大略省哈密尔顿市L8S 4L8加拿大中国医疗保健国际交流促进会循证医学分会中国研究型医院学会

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)导致的新型冠状病毒肺炎(COVID-19)自暴发以来迅速在全球蔓延,造成数以千万人感染及数十万患者死亡。基于研究证据的临床实践指南是诊治COVID-19的有力武器。在疫情早期阶段,该团队制定并发布... 详细信息

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)导致的新型冠状病毒肺炎(COVID-19)自暴发以来迅速在全球蔓延,造成数以千万人感染及数十万患者死亡。基于研究证据的临床实践指南是诊治COVID-19的有力武器。在疫情早期阶段,该团队制定并发布了《新型冠状病毒(2019-nCoV)感染的肺炎诊疗快速建议指南(标准版)》。疫情暴发后大量相关临床研究陆续开展并发表,新的证据可能会改变以前的推荐意见,更新指南的时机已经成熟。因此,该团队成立了由临床专家和方法学家组成的工作组,通过咨询一线临床专家提出并确定了与COVID-19管理相关的29个临床问题。通过系统检索有关COVID-19预防及诊疗的直接证据,使用GRAde方法评估证据质量并制订推荐意见,最终形成34条建议,其中6条强推荐,14条弱推荐,3条弱不推荐,11条为基于共识的建议;共涵盖4个方面,分别为药物预防,诊断(包括临床表现、RT-PCR检测、呼吸道标本、IgM和IgG抗体检测、CT检查、胸部X线片及无症状感染的CT特征),治疗方法[包括洛匹那韦-利托那韦、阿比朵尔、法匹拉韦、干扰素、瑞德西韦、抗病毒药的组合、羟氯喹/氯喹、白介素-6抑制剂、白介素-1抑制剂、糖皮质激素、清肺排毒汤、连花清瘟胶囊/颗粒、康复者血浆、肺移植、有创或无创通气、体外膜肺氧合支持(ECMO)]以及出院管理(包括复阳患者管理及出院标准)。此外,还制订了针对推荐意见的指南实施工具流程图,以期有力支持医护人员对COVID-19患者的照护。

关键词：新型冠状病毒肺炎 2019新型冠状病毒感染性疾病临床实践指南循证医学