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多星韭AwCHI 1的克隆与分析及真核表达载体的构建

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贵州师范大学学报（自然科学版） 2024年第2期42卷 118-126页

作者：赵鑫张艳肖松黄菊陈瑶孙威贵州师范大学生命科学学院/植物生理与发育调控重点实验室贵州贵阳550025 西南喀斯特山地生物多样性保护重点实验室贵州贵阳550025

查尔酮异构酶(Chalcone isomerase,CHI)是类黄酮物质合成途径中的关键酶,能催化柚皮素查尔酮生成柚皮素,进而转化生成各种类型的黄酮类化合物。根据多星韭(Allium wullichii)转录组测序结果,运用PCR技术克隆获取多星韭查尔酮异构酶的编... 详细信息

查尔酮异构酶(Chalcone isomerase,CHI)是类黄酮物质合成途径中的关键酶,能催化柚皮素查尔酮生成柚皮素,进而转化生成各种类型的黄酮类化合物。根据多星韭(Allium wullichii)转录组测序结果,运用PCR技术克隆获取多星韭查尔酮异构酶的编码基因(AwCHI 1),对基因序列进行分析,同时与真核表达载体pBI121进行连接,将其转入农杆菌GV3101感受态细胞中,完成农杆菌的转化。研究结果不仅为该基因的功能解析研究奠定了基础,也为多星韭类黄酮代谢途径的研究提供了重要基因资源。

关键词：类黄酮查尔酮异构酶多星韭真核表达载体

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蒸汽管道内流动输运过程及热损失分析

工程热物理学报 2024年第5期45卷 1418-1424页

作者：宋杨董祥瑞蔡天意周骛贺立军马文鹏鞠珊珊上海理工大学能源与动力工程学院上海200093 青岛海尔智能技术研发有限公司青岛266000

蒸汽管道冷凝换热是工业产品中的重要过程。分析不同管道条件对冷凝换热的影响规律和气液分布特性对蒸汽管道的设计及优化具有参考价值。本文采用VOF多相流模型对蒸汽管道内的流动和热损失进行模拟分析,主要对比了不同管道壁面厚度和不... 详细信息

蒸汽管道冷凝换热是工业产品中的重要过程。分析不同管道条件对冷凝换热的影响规律和气液分布特性对蒸汽管道的设计及优化具有参考价值。本文采用VOF多相流模型对蒸汽管道内的流动和热损失进行模拟分析,主要对比了不同管道壁面厚度和不同管道内径对换热特性的影响规律和气液行为,并对出口处90°拐角的二次流现象进行分析。研究结果表明,增加管道壁面厚度和减小管道内径尺寸会增大管道壁面单位面积的热流量,同时管道壁厚和内径增大引起壁面表面积增大使总热损失增加。流体流经90°拐角后形成的Dean涡使管道内壁面的冷凝水脱离壁面随高速气流进入蒸箱对食物蒸制产生不利影响。

关键词：蒸汽冷凝气液流动二次流传热

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基于车载激光点云的城市道路标线提取方法

激光与红外 2024年第3期54卷 396-403页

作者：周松刘荣陈志高段炬奎东华理工大学测绘与空间信息工程学院江西南昌330013 东华理工大学自然资源部环鄱阳湖区域矿山环境监测与治理重点实验室江西南昌330013 云南省核工业二〇九地质大队云南昆明650092

针对车载激光点云道路标线反射强度特性,提出了一种基于车载激光点云的城市道路标线提取方法。具体而言,首先提出一种联合布料模拟滤波和高差偏度平衡的地面滤波方法,利用偏度平衡滤波的自适应性,剔除布料滤波后残留的低矮植被的问题;... 详细信息

针对车载激光点云道路标线反射强度特性,提出了一种基于车载激光点云的城市道路标线提取方法。具体而言,首先提出一种联合布料模拟滤波和高差偏度平衡的地面滤波方法,利用偏度平衡滤波的自适应性,剔除布料滤波后残留的低矮植被的问题;随后利用基于法向量密度聚类以提取路面点云,并通过反距离加权插值将路面点云转为强度特征图;为了缓解标线提取出的锯齿状现象,引入快速引导滤波来平滑道路标线的边缘信息;最后采用最大熵阈值分割和形态学比值滤波对道路标线进行精化处理。实验表明,该方法能够有效地提取出道路标线点云,提取的平均召回率为80.98%,平均准确率为96.89%,平均综合评定指标为88.19%,能够利用道路标线点云强度信息较为完整地提取出道路标线点云。

关键词：点云布料模拟偏度平衡反距离加权插值快速引导滤波

关于Sylow p-子群的极大子群的F-可补性对群结构的影响

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山东大学学报（理学版） 2024年第6期59卷 98-102页

作者：高百俊汤菊萍高志超宋菊伊犁师范大学数学与统计学院新疆伊宁835000 无锡职业技术学院基础课部江苏无锡214121 华中师范大学数学与统计学院湖北武汉430079 扬州大学数学科学学院江苏扬州225002

结合群类理论,将群类S_(p)^(*)拓展到群类S_(p)^(2)^(*)和S_(p)^(3)^(*),并由此定义S_(p)^(i)^(*)-可补子群,i=1,2,3。进一步利用Sylow p-子群的极大子群的S_(p)^(i)^(*)-可补性质研究广义p-可解群的构造。

关键词： Sylow p-子群极大子群可补子群广义p-可解群

Quantitative detection of citrate for early stage diagnosing of prostate cancer:Discriminating normal to cancer in prostate tissues

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Chinese Chemical Letters 2024年第2期35卷 501-506页

作者： Selvaraj Muthusamy Kanagaraj Rajalakshmi Palanisamy Kannan Yun-Sik Nam Dongwei Zhu Yeonggil Seo Jong-Won song Dong Nyoung Heo Il Keun Kwon Yuanguo Xu School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China College of Biological Chemical Sciences and EngineeringJiaxing UniversityJiaxing 314001China Advanced Analysis Center Korea Institute of Science & TechnologySeongbuk-guSeoul02792Republic of Korea School of Medicine Jiangsu UniversityZhenjiang 212013China Department of Chemistry Education Daegu UniversityGyeongsan-siGyeongsangbuk-do 38453Republic of Korea Department of Dental Materials School of DentistryKyung Hee UniversitySeoulRepublic of Korea

Prostate cancer(PC)biomarker-citrate detection is clinically important to diagnose PC in early *** iodide(Q)conjugated indole-phenylboronic acid(IB)was designed as a red-emissive QIB probe for the detection of citrate through Lewis acid-base reaction and intramolecular charge transfer(ICT)sensing *** acid acts as Lewis acid as well as citrate(Lewis base)recognition *** probe reacted with citrate,showing enhanced red *** the probe has excellent water solubility and great biocompatibility,practical application in biological systems is *** was monitored precisely in the mitochondria organelle(in vitro)of living cells with a positive charge on ***,endogenous(in situ)citrate was detected quantitatively to discriminate non-cancerous and PC mice,observed strong and lower(negligible)emission intensity on non-cancerous and cancerous prostate tissues,***,the concentration of citrate is higher in healthy prostate compared with PC ***,the analysis of sliced prostate tissues can give PC-related information for clinical diagnosis to prevent and treat PC in the initial ***,we believe that the present probe is a promising biochemical reagent in diagnosing PC.

关键词： Prostate cancer Biomarker-citrate Boronic acid Lewis acid/base-ICT Red-emissive Mitochondria targeting Prostate tissue

基于雷洛昔芬的多重刺激响应性单组分室温磷光分子晶体

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Science Bulletin 2024年第9期69卷 1237-1248页

作者：潘智超宋金明张莎莎曾平梅菊曲大辉 Key Laboratory for Advanced Materials Joint International Research Laboratory of Precision Chemistry and Molecular EngineeringFeringa Nobel Prize Scientist Joint Research CenterFrontiers Science Center for Materiobiology and Dynamic ChemistryInstitute of Fine ChemicalsSchool of Chemistry&Molecular EngineeringEast China University of Science&TechnologyShanghai 200237China

Simultaneously achieving room-temperature phosphorescence(RTP) and multiple-stimuli responsiveness in a single-component system is of significance but remains challenging. Crystallization has been recognized to be a workable strategy to fulfill the above task. However, how the molecular packing mode affects the intersystem crossing and RTP lifetime concurrently remains unclear so far. Herein, four economic small-molecular compounds, analogues of the famous drug raloxifene(RALO), are facilely synthesized and further explored as neat single-component and stimuli-responsive RTP emitters via crystallization engineering. Thanks to their simple structures and high ease to crystallize, these raloxifene analogues function as models to clarify the important role of molecular packing in the RTP and stimuliresponsiveness properties. Thorough combination of the single-crystal structure analysis and theoretical calculations clearly manifests that the tight antiparallel molecular packing mode is the key point to their RTP behaviors. Interestingly, harnessing the controllable and reversible phase transitions of the two polymorphs of RALO-OAc driven by mechanical force, solvent vapor, and heat, a single-component multilevel stimuli-responsive platform with tunable emission color is established and further exploited for optical information encryption. This work would shed light on the rational design of multi-stimuli responsive RTP systems based on single-component organics.

关键词： Crystal engineering Molecular packing Organic room-temperature phosphorescence(RTP) Polymorph Stimuli-responsiveness

基于大型无人机航磁全轴梯度测量技术研究与应用

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地球物理学报 2024年第8期67卷 3162-3172页

作者：郭华鞠星韩松王萌王明李冰梁韧中国自然资源航空物探遥感中心北京100086

目前,我国航空物探在远海地区和青藏高原地区的工作程度并不高,这主要是由于我国现有有人机航空物探飞行平台的续航里程不够远或者无法在高海拔地区开展大比例尺、低高度飞行测量工作.由于彩虹4无人机的续航时间达到20余小时,飞行高度可... 详细信息

目前,我国航空物探在远海地区和青藏高原地区的工作程度并不高,这主要是由于我国现有有人机航空物探飞行平台的续航里程不够远或者无法在高海拔地区开展大比例尺、低高度飞行测量工作.由于彩虹4无人机的续航时间达到20余小时,飞行高度可达7300 m,经过项目研制,基于彩虹4无人机航磁全轴梯度测量系统突破了探测装置的集成设计、磁干扰特性的优化提升等一系列关键技术,首次实现了基于无人机的航磁总场、横向梯度、垂直梯度的一站式测量,航磁总场补偿后标准差优于±30 pT,横向梯度补偿后标准差优于±2 pT/m,垂向梯度补偿后标准差优于±6 pT/m,达到同类测量系统的国际领先水平,大大提升了我国在艰难地区和远海地区的勘查能力.

关键词：大型无人机航磁全轴梯度横向梯度垂向梯度

Xanthogranulomatous cholecystitis managed by laparotomy may go through troublesome clinical course: Reflection of severe inflammation

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Hepatobiliary & Pancreatic Diseases International 2023年第2期22卷 210-212页

作者： hee ju Kim Kwang Yeol Paik Department of Surgery Yeoiudo St.Mary’s HospitalCollege of MedicineThe Catholic University of Korea College of MedicineSeoul 07345Korea

To the Editor: Xanthogranulomatous cholecystitis(XGC) is an uncommon inflammatory disease of the gallbladder, and its incidence is reported to be 1.3%-5.2% [1]. XGC is diagnosed by histopathological examination, characterized by severe inflammatory destruction followed by a granulomatous reaction, marked proliferative fibrosis, and infiltration of inflammatory cells [2].

关键词： granuloma cholecystitis inflammation

A multicenter prospective study on the management of hepatoblastoma in children:a report from the Chinese Children's Cancer Group

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World Journal of Pediatrics 2024年第6期20卷 590-601页

作者： Meng-Jie Tang Xiao-Li Ma Xiang-Ling He Wei-Hua Pan Xiao-Hong Zhang Sha-Yi Jiang ju Gao Fu Lie Wei Yao song Gu Wei-Ling Zhang Qiang Zhao Shi-Hao Huang Yong-jun Fang Wei Liu Hui-Zhong Niu Chun-Mei Wang Li-Rong Sun Hui Gao Yun-Peng Dai Shun-Gen Huang Zhi-Yong Zhong Xi-Ge Wang Zhong-Rong Li Liang-Chun Yang Ye-Ming Wu Huan-Min Wang Xin Sun Xiao-jun Yuan Department of Pediatric Hematology/Oncology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNo.1665Kongjiang RoadYangpu DistrictShanghai 200092China Medical Oncology Department Pediatric Oncology CenterBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Hematology/Oncology Children's Medical CenterHunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 41005China Department of Pediatric Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Hematology/Oncology Guangzhou Women and Children's Medical CenterNational Children's Medical Center for South Central RegionGuangzhou 510623China Department of Hematology Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200062China Department of Pediatrics West China Second University HospitalSichuan UniversityChengdu 610041China Department of Hematology/Oncology Qilu Children's Hospital of Shandong UniversityJinan 250022China Department of Pediatric Surgery Children's Hospital of Fudan UniversityShanghai 201102China Department of General Surgery Shanghai Children's Medical Center(National Children's Medical Center-Shanghai)Shanghai Jiao Tong University School of MedicineShanghai 200127China Department of Pediatrics Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Pediatric Oncology Tianjin Medical University Cancer Institute and HospitalTianjin 300060China Department of Hematology/Oncology Children's Hospital of Nanjing Medical UniversityNanjing 210008China Department of Hematology/Oncology Henan Children's HospitalZhengzhou 450018China Department of Pediatric General Surgery Hebei Children's Hospital of Hebei Medical UniversityShijiazhuang City 050031China Children's Hospital the First Affliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Paediatric

Background This study aimed to identify survival risk factors in Chinese children with hepatoblastoma(HB)and assess the effectiveness of the new treatment protocol proposed by the Chinese Children's Cancer Group(CCCG)in *** A multicenter,prospective study that included 399 patients with HB from January 2015 to june 2020 was *** demographics,treatment protocols,and other related information were *** regression models and Kaplan-Meier curve methods were *** The 4-year event-free survival(EFS)and overall survival(OS)were 76.9 and 93.5%,*** 4-year EFS rates for the very-low-risk,low-risk,intermediate-risk,and high-risk groups were 100%,91.6%,81.7%,and 51.0%,*** 4-year 0S was 100%,97.3%,94.4%,and 86.8%,*** regression analysis found that age,tumor rupture(R+),and extrahepatic tumor extension(E+)were independent prognostic factors.A total of 299 patients had complete remission,and 19 *** with declining alpha-fetoprotein(AFP)>75%after the first two cycles of neoadjuvant chemotherapy had a better EFS and OS than those≤75%.Conclusions The survival outcome of HB children has dramatically improved since the implementation of CCCG-HB-2016 ***≥8 years,R+,and E+were independent risk factors for *** with a declining AFP>75%after the first two cycles of neoadjuvant chemotherapy had better EFS and OS.

关键词： Alpha-fetoprotein Hepatoblastoma Multicenter Prospective study Survival