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Compaction Rate of an Early Permian Volcanic Tuff from Wuda Coalfield, Inner Mongolia

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Acta Geologica Sinica(English Edition) 2013年第5期87卷 1242-1249页

作者： WANG Jun he xuezhi hermann W.PFEFFERKORN WANG Jinrong State Key Laboratory of Palaeobiology and Stratigraphy (LPS) and Department of Palaeobotany and Palynology Nanjing Institute of Geology and PalaeontologyChinese Academy of Sciences State Key Laboratory of Systematic and Evolutionary Botany (LSB) Institute of BotanyChinese Academy of Sciences Department of Earth and Environmental Science University of Pennsylvania College of Earth and Environment Sciences Lanzhou University

Compaction rates of sediments or volcaniclastic material are needed to reconstruct original thickness of a bed, which in turn is required to reconstruct subsidence rates, sea-level rise, or in the case of volcanielastic, the location or direction of the eruption site. The knowledge of compaction rates can also aid in the reconstruction of deformed fossils. The known shape of deformed fossils can allow the determination of the compaction they experienced. here we report the compaction rate in an early Permian volcanic tuff from Wuda, Inner Mongolia, determined from the deformation of standing tree fern stems of known anatomy. The compaction rate has been found to be 0.56 in this case, indicating that 44% of original thickness remains.

关键词： Compaction volcanic tuff Early Permian tree trunk Wuda

Paleoecology of Oligocarpia gothanii Halle from the Middle Permian of Southeastern Shanxi,North China

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Acta Geologica Sinica(English Edition) 2015年第4期89卷 1063-1075页

作者： he xuezhi WAN Mingli YAN Mengxiao CheNG Chen WANG Shijun WANG Jun State Key Laboratory of Systematic and Evolutionary Botany (LSB) Institute of BotanyChinese Academy of Sciences LPS Nanjing Institute of Geology and PalaeontologyChinese Academy of Sciences University of Chinese Academy of Sciences

Fossil ferns are abundant and diverse in the Permian Cathaysian Flora of Shanxi, North China. Although plants assemblages of the Carboniferous and Permian have been extensively investigated, their palaeoecology and especially the paleoecology of ferns has not been studied in detail. Recent reinvestigation of Oligocarpia gothanii has revealed its growth habit and cloning reproduction strategy, but most previous studies lack integrated sedimentological and taphonomic data. In this study, new materials of O. gothanii have been collected from a floodplain setting in the middle Permian Lower Shihhotse Formation of southeastern Shanxi. These plant fossils were found in a lenticular claystone associated with rooting structures. They are characterized by aphlebia at the base of the penultimate rachis. Sedimentological, taphonomic and morphological analyses were conducted to understand the growth habit and ecology of the fern. The result indicates that the Oligocarpia gothanii had a prostrate, ground cover growth habit, and was dominant in pioneer floras that colonized disturbed floodplains.

关键词： palaeoecology plant taphonomy middle Permian Oligocarpia gothanii Halle

A novel long non-coding RNA NFIA-AS1 is down-regulated in gastric cancer and inhibits proliferation of gastric cancer cells

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The Journal of Biomedical Research 2019年第6期33卷 371-381页

作者： Jing Wang xuezhi he Xiyi Lu Muhammad Amin Karim Dengshun Miao Erbao Zhang Departments of Anatomy Histology and Embryologythe Research Center for Bone and Stem CellsNanjing Medical UniversityNanjingJiangsu 211166China Department of Oncology the First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210009China Department of Epidemiology and Biostatistics Jiangsu Key Lab of Cancer BiomarkersPrevention and TreatmentCollaborative Innovation Center for Cancer Personalized MedicineNanjing Medical UniversityNanjingJiangsu 211166China

Gastric cancer is one of the most common malignant gastrointestinal tumors whose morbidity and mortality account for the second and third place respectively in malignant tumors in *** an important participant in tumor biology,the abnormal expression of long non-coding RNA(lncRNAs)in cancer cells is closely related to the occurrence and development of tumors and plays the role of oncogenes or tumor suppressor *** this study,we identified a novel lncRNA NFIA antisense RNA 1(NFIA-AS1)and explored its role and clinical significance in gastric ***-time quantitative PCR was performed to detect the expression of NFIA-AS1 in tumor tissues and corresponding normal tissues from 42 pairs of gastric cancer *** lower expression of NFIA-AS1 was significantly associated with larger tumor size,lower histological grade,and advanced TNM ***-meier analysis showed that NFIA-AS1 expression could be used as an independent predictor of overall *** also demonstrated that overexpression of NFIA-AS1 significantly inhibited the proliferation of gastric cancer cells through affecting p16 *** conclusion,our results suggest that the lncRNA NFIA-AS1 may play the role of tumor suppressor gene,and serve as a biomarker for prognosis or progression of gastric cancer.

关键词： gastric cancer long non-coding RNA NFIA antisense RNA 1(NFIA-AS1) cell proliferation

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人工血管翻转吻合技术在主动脉外科的应用

中华胸心血管外科杂志 2021年第3期37卷 188-192页

作者：史泽鹏何学志大连医科大学研究生院 116044 大连市中心医院心脏大血管外科 116033

人工血管与主动脉吻合是主动脉疾病外科治疗最重要的操作步骤,临床上涌现出了多种吻合方式及预防和消除吻合口出血的处理方法。其中人工血管末端外翻部分插入主动脉或内翻整体插入主动脉的吻合方式增大了移置物与主动脉壁贴合面积,明显... 详细信息

人工血管与主动脉吻合是主动脉疾病外科治疗最重要的操作步骤,临床上涌现出了多种吻合方式及预防和消除吻合口出血的处理方法。其中人工血管末端外翻部分插入主动脉或内翻整体插入主动脉的吻合方式增大了移置物与主动脉壁贴合面积,明显降低了潮汐血流的冲脱作用和对吻合口的侧向力。因而其降低吻合后出血风险、术中缝合操作简化及吻合口出血容易处理的优点突出。不同名称的类似技术在主动脉病变的外科治疗中多有应用并取得了良好的吻合效果。本文将该技术统一称作"人工血管翻转吻合技术",系统阐述其在主动脉外科的应用演变,以期进一步加深对该技术的认识。

关键词：主动脉疾病主动脉壁吻合技术人工血管吻合方式吻合口出血风险外科治疗

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应用自回归模型的条码图像盲去模糊算法

福建电脑 2020年第1期36卷 1-5页

作者：何学智新大陆数字技术股份有限公司

条码的解码景深是条码解码能力的重要评估指标。解码景深越长,对模糊条码的识别能力要求越高。该问题是一个典型的盲去模糊问题。本文结合条码的二值化特性,基于自回归模型,设计相应的优化函数和优化方法,提出条码图像盲去模糊算法Blind... 详细信息

条码的解码景深是条码解码能力的重要评估指标。解码景深越长,对模糊条码的识别能力要求越高。该问题是一个典型的盲去模糊问题。本文结合条码的二值化特性,基于自回归模型,设计相应的优化函数和优化方法,提出条码图像盲去模糊算法Blind-TVDWSAR。通过仿真实验和实拍图像实验验证了所提算法的有效性。将该算法嵌入条码识读设备发现,相比未做盲去模糊,条码解码景深有至少5cm的延拓效果。

关键词：盲去模糊自回归模型条码解码景深

The autophagy-lysosome pathway:a potential target in the chemical and gene therapeutic strategies for Parkinson’s disease

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Neural Regeneration Research 2025年第1期20卷 139-158页

作者： Fengjuan Jiao Lingyan Meng Kang Du xuezhi Li School of Mental health Jining Medical UniversityJiningShandong ProvinceChina Shandong Collaborative Innovation Center for Diagnosis Treatment and Behavioral Interventions of Mental DisordersInstitute of Mental HealthJining Medical UniversityJiningShandong ProvinceChina

Parkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such asα-synuclein in *** one of the major intracellular degradation pathways,the autophagy-lysosome pathway plays an important role in eliminating these *** evidence has shown that upregulation of the autophagy-lysosome pathway may contribute to the clearance ofα-synuclein aggregates and protect against degeneration of dopaminergic neurons in Parkinson’s ***,multiple genes associated with the pathogenesis of Parkinson’s disease are intimately linked to alterations in the autophagy-lysosome ***,this pathway appears to be a promising therapeutic target for treatment of Parkinson’s *** this review,we briefly introduce the machinery of ***,we provide a description of the effects of Parkinson’s disease–related genes on the autophagy-lysosome ***,we highlight the potential chemical and genetic therapeutic strategies targeting the autophagy–lysosome pathway and their applications in Parkinson’s disease.

关键词： autophagy chemical therapy gene therapy Parkinson’s disease α-synuclein

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心脏震荡伤

临床心血管病杂志 2008年第11期24卷 803-804页

作者：何学志刘继红谷天祥大连市中心医院心胸外科辽宁大连116033 中国医科大学附属第一医院心外科

@@ 心脏震荡伤属于钝性心脏损伤,但其发病过程及临床特点又完全不同于一般的心脏钝性挫伤.心脏震荡伤多是在运动过程中发生,发病过程短暂,病死率很高.本文就心脏震荡伤的概念、临床特点、发病机制、治疗和预防等进行综述.

关键词：心脏震荡伤发病机制治疗

肺超声与胸部X线对儿童急性肺创伤的诊断价值比较

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中华超声影像学杂志 2021年第11期30卷 988-992页

作者：陈伟玲夏焙林洲范舒旻何学智李志惠深圳市儿童医院超声科 518038

目的探讨肺超声与胸部X线在识别儿童急性胸部外伤性内脏损伤诊断中的价值。方法回顾性分析2017年1月至2021年1月于深圳市儿童医院收治的46例胸部外伤患儿。以胸部CT结果为金标准,分析比较肺超声和X线检查对儿童急性创伤血气胸、肺挫伤... 详细信息

目的探讨肺超声与胸部X线在识别儿童急性胸部外伤性内脏损伤诊断中的价值。方法回顾性分析2017年1月至2021年1月于深圳市儿童医院收治的46例胸部外伤患儿。以胸部CT结果为金标准,分析比较肺超声和X线检查对儿童急性创伤血气胸、肺挫伤的诊断效能。结果肺超声诊断气胸、血胸和肺挫伤的敏感性分别为0.79、0.86、0.86,特异性分别为0.98、0.75、0.80。肺超声诊断气胸、血胸和肺挫伤的ROC曲线下面积分别为0.889(95%CI=0.798~0.979,P<0.001)、0.804(95%CI=0.707~0.901,P<0.001)和0.831(95%CI=0.623~1.000,P<0.001)。X线诊断气胸、血胸和肺挫伤的ROC曲线下面积分别为0.674(95%CI=0.544~0.803,P=0.008)、0.645(95%CI=0.517~0.772,P=0.026)和0.547(95%CI=0.289~0.805,P=0.724)。ROC曲线下面积的比较表明肺超声对气胸、血胸和肺挫伤的诊断优于X线平片(均P<0.05)。结论肺超声在初步评估胸部钝性创伤时比胸部X线有更高的敏感性和准确性。对于急性胸部钝性创伤患儿应优先考虑肺部超声检查。

关键词：超声检查急诊创伤肺

扩大外膜内翻并翻转吻合与主动脉包裹后右房分流技术处理A2型夹层根部的近期疗效对比

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临床心血管病杂志 2022年第3期38卷 210-215页

作者：史泽鹏何学志庄熙晶高峰高洋刘巍石磊王文君大连市中心医院心脏大血管外科辽宁大连116033

目的:对比扩大外膜内翻并翻转吻合与主动脉包裹后右房分流两种手术方式的围术期差异,评价其术后及近期疗效,为手术处理策略提供新选择。方法:回顾性分析2017年2月—2020年3月我中心行手术治疗的68例急性A2型主动脉夹层患者。其中外膜内... 详细信息

目的:对比扩大外膜内翻并翻转吻合与主动脉包裹后右房分流两种手术方式的围术期差异,评价其术后及近期疗效,为手术处理策略提供新选择。方法:回顾性分析2017年2月—2020年3月我中心行手术治疗的68例急性A2型主动脉夹层患者。其中外膜内翻组22例应用扩大外膜内翻并翻转吻合技术;包裹组46例应用主动脉包裹后右房分流技术。比较两组患者术前、术中及术后近期随访结果,评价其疗效及安全性。结果:外膜内翻组手术总时长、停机至关皮时间较包裹组明显缩短(P<0.05)。对比术后2周内及术后12个月心脏超声可见包裹组窦管交界直径明显扩张(P<0.05)。随访节点内外膜内翻组技术可有效闭合夹层假腔,降低吻合口漏风险,同时其复位主动脉瓣膜的效果维持情况优于包裹组技术(P<0.05),两组之间再手术相关事件发生情况存在明显差异(P<0.05)。结论:外膜内翻并翻转吻合技术处理A2型主动脉夹层较主动脉包裹后右房分流技术明显缩短了手术时间并可预防窦管交界的近期扩张,应用其处理主动脉根部安全且可靠,近期手术疗效维持更佳。

关键词：吻合技术主动脉夹层主动脉根部疗效