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辅助生殖技术助孕患者的睡眠障碍及非药物干预的研究进展

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国际生殖健康/计划生育杂志 2024年第3期43卷 234-237页

作者：贺晴雯李喜红中信湘雅生殖与遗传专科医院湖南省生殖与遗传临床医学研究中心

辅助生殖技术助孕患者作为特殊群体，不同于其他疾病，由于其生理和心理社会因素并存，容易出现睡眠障碍。综述辅助生殖技术助孕患者睡眠障碍的现状、评估工具及非药物干预方法，包括采用适宜的工具有效评估患者的睡眠障碍程度，制定合... 详细信息

辅助生殖技术助孕患者作为特殊群体，不同于其他疾病，由于其生理和心理社会因素并存，容易出现睡眠障碍。综述辅助生殖技术助孕患者睡眠障碍的现状、评估工具及非药物干预方法，包括采用适宜的工具有效评估患者的睡眠障碍程度，制定合理的个体化非药物干预措施，如数字认知行为疗法、正念减压疗法、音乐疗法、有氧运动、抗阻运动以及渐进式肌肉放松等方法可以改善辅助生殖技术助孕患者的睡眠质量，为今后开展我国辅助生殖技术助孕患者睡眠障碍的评估及非药物干预方案提供参考。

关键词：生殖技术,辅助不育,女(雌)性睡眠障碍数字认知行为疗法正念减压疗法音乐疗法运动疗法

Low soil carbon saturation deffcit limits the abundance of cbbL-carrying bacteria under long-term no-tillage maize cultivation in northern China

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Journal of Integrative Agriculture 2022年第8期21卷 2399-2412页

作者： YIN Tao QIN Hong-ling YAN Chang-rong LIU Qi he wen-qing College of Resources and Environment Qingdao Agricultural UniversityQingdao 266109P.R.China Institute of Environment and Sustainable Development in Agriculture Chinese Academy of Agricultural SciencesBeijing 100081P.R.China Key Laboratory of Subtropical Agro-ecology Institute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125P.R.China Key Laboratory of Prevention and Control of Residual Pollution in Agricultural Film Ministry of Agriculture and Rural AffairsBeijing 100081P.R.China

The responses of cbbL-carrying bacteria to different levels of soil carbon saturation deficits(SCSD)under tillage managements are largely *** assessed the influence of SCSD on the abundance and diversity of cbbLcarrying bacteria under long-term no-tillage with residue retention(NT)and conventional tillage without residue retention(CT)cultivation systems in *** found SCSD was smaller under NT than under CT in the 0-15 cm soil *** abundance and the Shannon diversity of cbbL-carrying bacteria in the NT treatment were lower than in the CT *** carbon saturation and cbbL gene abundance showed a significant positive correlation,but there was no correlation between soil carbon saturation and cbbL gene ***,the long-term NT practice decreased cbbL-carrying bacteria diversity and altered the community structure of the cbbL-carrying *** results indicated that low SCSD limited the abundance of cbbL-carrying bacteria,but there was no relationship between low SCSD and diversity of cbbLcarrying *** suggest that further studies of cbbL-carrying bacteria carbon sequestration rates and capacity should be based on the effect of management practices on cbbL-carrying bacteria abundance and *** study has important implications for the relationship between the biological and physicochemical mechanisms in CO_(2) fixation.

关键词： conservation tillage soil carbon saturation cbbL-carrying bacteria abundance and diversity

经阴道瘢痕憩室修补术治疗子宫瘢痕憩室效果分析

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中国妇幼保健 2024年第5期39卷 777-780页

作者：刘云玥张超贺青文胡雅淇范文生中国人民解放军总医院第七医学中心妇产科北京100853 西安市人民医院(西安市第四医院)妇产科西安医学院

目的分析经阴道瘢痕憩室修补术治疗子宫瘢痕憩室的效果,建立支持经阴道手术治疗子宫瘢痕憩室的循证医学证据。方法选取2021年3月—2022年3月中国人民解放军总医院第七医学中心收治的32例剖宫产瘢痕憩室患者为研究对象,随机均分为观察组... 详细信息

目的分析经阴道瘢痕憩室修补术治疗子宫瘢痕憩室的效果,建立支持经阴道手术治疗子宫瘢痕憩室的循证医学证据。方法选取2021年3月—2022年3月中国人民解放军总医院第七医学中心收治的32例剖宫产瘢痕憩室患者为研究对象,随机均分为观察组与对照组,分别接受经阴道瘢痕憩室修补术以及腹腔镜瘢痕憩室修补术治疗,记录患者术前、术中、术后相关临床数据和患者住院时间、术中出血量,比较两组治疗效果。结果观察组治疗总有效率(93.75%)与对照组(87.50%)比较,差异无统计学意义(P>0.05);观察组术中出血量[(50.46±4.65)ml]与对照组[(54.59±3.48)ml]比较,差异无统计学意义(P>0.05),观察组手术时间[(102.59±5.19)min]少于对照组[(130.78±4.53)min],差异有统计学意义(P0.05)。两组术中并发症发生率比较,差异无统计学意义(P>0.05);两组术后复发率比较,差异无统计学意义(P>0.05)。结论针对子宫瘢痕憩室采用经阴道手术治疗,花费以及复发率低,远期疗效好,是一种应用价值较高的治疗方式。

关键词：经阴道瘢痕憩室修补术剖宫产瘢痕憩室微创

Effect of Sc on Al_(3)Fe phase and mechanical properties of as-cast AA5052 aluminum alloy

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China Foundry 2024年第3期21卷 257-264页

作者： Yang Li qing Yu Feng-feng Chen Jia-wen he Hong-mei Yang Meng-nie Li Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China

The AA5052 aluminum alloy is widely used in automobile and aerospace manufacturing,and with the development of light-weight alloys,it is required that these materials exhibit better mechanical *** studies have demonstrated that the addition of Sc to aluminum alloys can improve both the microstructure and properties of the *** this study,the effect of Sc on the Fe-rich phase and properties of the AA5052 aluminum alloy was studied by adding 0%,0.05%,0.2%,and 0.3%*** results show that with the increase of Sc,the coarse needle-like Fe-rich phase gradually transforms into Chinese-script and then nearly spherical particles,reduce the size of Fe-rich phase,and refine the grain with increase of high angle grain boundaries(HAGBs).These microstructure changes enhance the strength of the AA5052 alloy through Sc *** ductility of the alloy is obviously improved because the addition of a lower amount of Sc changes the morphology of Fe-rich phase from needle-like into a Chinese-script,and it is subsequently reduced as a result of significant increase in HAGBs with increasing Sc content.

关键词： AA5052 aluminum alloy Al3Fe phase mechanical properties grain boundary

Multi-Scale Pore Structure heterogeneity in Tuff Reservoirs Investigated with Multi-Experimental Method and Fractal Dimensions in Chang 7 Formation,Southern Ordos Basin

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Journal of Earth Science 2024年第2期35卷 666-686页

作者： Hao Lu qing Li Dali Yue Dongdong Xia Shenghe Wu Lang wen Yu he State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China College of Geosciences China University of PetroleumBeijing102249China Petroleum Exploration and Development Institute of SINOPEC Beijing100083China

The tight tuff reservoir is an unusual type of unconventional reservoir with strong ***,there is a lack of research on the microscopic pore structure that causes the heterogeneity of tuff *** the Chang 7 Formation in Ordos Basin,China as a case study,carbon-dioxide gas adsorption,nitrogen gas adsorption and high-pressure mercury injection are integrated to investigate the multi-scale pore structure characteristics of tuff ***,the fractal dimension is introduced to characterize the complexity of pore structure in tuff *** this multi-experimental method,the quantitative characterizations of the full-range pore size distribution of four tuff types were obtained and compared in the size ranges of micropores,mesopores and *** dimension curves derived from full-range pores are divided into six segments as D1,D2,D3,D4,D5 and D6 corresponding to fractal characteristics of micropores,smaller mesopores,larger mesopores,smaller macropores,medium macropores and larger macropores,*** macropore volume,average macropore radius and fractal dimension D5 significantly control petrophysical *** larger macropore volume,average macropore radius and D5 correspond to favorable pore structure and good reservoir quality,which provides new indexes for the tuff reservoir *** study enriches the understanding of the heterogeneity of pore structures and contributes to unconventional oil and gas exploration and development.

关键词： tuff reservoir pore structure carbon-dioxide gas adsorption nitrogen gas adsorption high-pressure mercury injection fractal dimension petroleum geology

New recessive compound heterozygous variants of RP1L1 in RP1L1 maculopathy

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 107-112页

作者： wen-Chao Cao qing-Shan Chen Run Gan Tao Huang Xiao-he Yan The Second Clinical Medical College Jinan UniversityShenzhen 518040Guangdong ProvinceChina Shenzhen Eye Hospital Jinan UniversityShenzhen Eye InstituteShenzhen 518040Guangdong ProvinceChin

AIM:To identify a maculopathy patient caused by new recessive compound heterozygous variants in ***:Comprehensive retinal morphological and functional examinations were evaluated for the patient with RP1L1 *** sequence capture array technique was used to screen potential pathologic *** chain reaction and Sanger sequencing were used to confirm the screening ***:Fundus examination showed round macular lesions appeared in both *** coherence tomography showed that the inner segment/outer segment continuity was disorganized and disruptive in the left eye,but it was uneven and slightly elevated in the right *** autofluorescence showed patchy hyper-autofluorescence in the *** field examination indicates central defects in both ***(ERG)and multifocal ERG showed no obvious *** fluorescein angiography in the macula showed obviously irregular hyper-fluorescence in the right eye and slightly hyper-fluorescence in the left *** found that the proband carried a missense variant(c.1972C>T)and a deletion variant(c.4717_4718del)of RP1L1,which were originated from the parents and formed compound heterozygous *** variants are likely pathogenic according to the ACMG *** imaging,ERG and detailed medical history are important diagnostic tools for differentiating between acquired and inherited retinal ***:A maculopathy case with detailed retinal phenotype and new recessive compound heterozygous variants of RP1L1 is identified in a Chinese family,which expands the understanding of phenotype and genotype in RP1L1 maculopathy.

关键词： maculopathy recessive compound heterozygous variants RP1L1

Corrugated Graphene Paper Reinforced Silicone Resin Composite for Efficient Interface Thermal Management

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Chinese Journal of Polymer Science 2024年第7期42卷 1002-1014,I0010页

作者： Bo-wen Wang heng Zhang qing-Xia he Hui-Tao Yu Meng-Meng Qin Wei Feng Tianjin Key Laboratory of Composite and Functional Materials School of Materials Science and EngineeringTianjin UniversityTianjin300350China International Engineering Institute Tianjin UniversityTianjin300350China

With the rapid development of high-power-density electronic devices,interface thermal resistance has become a critical barrier for effective heat management in high-performance electronic ***,there is an urgent demand for advanced thermal interface materials(TIMs)with high cross-plane thermal conductivity and excellent compressibility to withstand increasingly complex operating *** achieve this aim,a promising strategy involves vertically arranging highly thermoconductive graphene on ***,with the currently available methods,achieving a balance between low interfacial thermal resistance,bidirectional high thermal conductivity,and large-scale production is ***,we prepared a graphene framework with continuous filler structures in in-plane and cross-plane directions by bonding corrugated graphene to planar graphene *** interface interaction between the graphene paper framework and polymer matrix was enhanced via surface functionalization to reduce the interface thermal *** resulting three-dimensional thermal framework endows the polymer composite material with a cross-plane thermal conductivity of 14.4 W·m^(-1)·K^(-1)and in-plane thermal conductivity of 130W·m^(-1)·K^(-1)when the thermal filler loading is 10.1 wt%,with a thermal conductivity enhancement per 1 wt%filler loading of 831%,outperforming various graphene structures as *** its high thermal conductivity,low contact thermal resistance,and low compressive modulus,the developed highly thermoconductive composite material demonstrates superior performance in TIM testing compared with TFLEX-700,an advanced commercial TIM,effectively solving the interfacial heat transfer issues in electronic *** novel filler structure framework also provides a solution for achieving a balance between efficient thermal management and ease of processing.

关键词： Graphene paper Vertically aligned structure Cross-plane thermal conductivity Low compressive modulus Thermal interface material

All types of base conversions allowed by base editors

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Science China(Life Sciences) 2024年第2期67卷 431-433页

作者： Shun-qing Liang wen Xue RNA Therapeutics Institute UMass Chan Medical SchoolWorcester 01655USA Department of Molecular Cell and Cancer BiologyUMass Chan Medical SchoolWorcester 01655USA Department of Molecular Medicine UMass Chan Medical SchoolWorcester 01655USA Li Weibo Institute for Rare Diseases Research UMass Chan Medical SchoolWorcester 01655USA

Base editors(BEs) hold great promise as tools for introducing single-base-pair changes in both basic research and therapeutic applications(Rees and Liu,2018).Base editors are composed of a Cas9 nickase fused to a DNA-modifying enzyme,which chemically modifies nucleobases within a specific targeting window near the Cas9-binding site.

关键词： base bases allowed

Response of carbon footprint to plastic film mulch application in spring maize production and mitigation strategy

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Journal of Integrative Agriculture 2021年第7期20卷 1933-1943页

作者： CheN Bao-qing Shahar BARAM DONG wen-yi he wen-qing LIU En-ke YAN Chang-rong Institute of Environment and Sustainable Development in Agriculture Chinese Academy of Agricultural SciencesBeijing 100081P.R.China Institute for Soil Water and Environmental SciencesAgricultural Research Organization(ARO)Volcani Research CenterBet Dagan 50250Israel

Producing more food with a lower environmental cost is one of the most crucial challenges worldwide. Plastic mulching has developed as one of the most dominant practices to improve crop yields, however its impacts on greenhouse gas(GHG) emissions during the production life cycle of a crop are still unclear. The objective of this work is to quantify the impacts of plastic film on GHG emissions and to reduce GHG emissions with innovative agronomic practices. Carbon footprint per unit of area(CFa), per unit of maize grain yield(CFy), and per unit of economic output(CFe) were evaluated for three maize cultivation systems: a no mulch system, a conventional plastic mulching system(PM) and a biennial plastic mulching pattern, namely a ’one film for 2 years’ system(PM2), during 2015–2018 in a maize field located on the Loess Plateau of China. The results suggested that PM induced a 24% improvement in maize yields during the four experimental years compared to a no-mulch treatment(NM). However, PM dramatically increased the CFa by 69%, 59% of which was created by the input of the plastic film material, and 10% was created by increases in the soil N2O emissions. The yield improvements from PM could not offset the increases in CFa, and CFy and CFe were both increased by 36%. Shifting from PM to PM2 did not reduce crop yields, but it led to a 21% reduction in CFa and 23% reductions in CFy and CFe due to the reduced input amount of plastic film, decreased soil N2O emissions, and less diesel oil used for tillage. Compared to NM, CFy and CFe were only 5% higher in PM2. This study highlights the necessity of reducing the amount of plastic film input in the development of low-carbon agriculture and shifting from conventional PM cultivation to PM2 could be an efficient option for mitigating GHG emissions while sustaining high crop yields in plastic mulched fields.

关键词： carbon footprint greenhouse gas plastic film maize