检索结果-南通市图书馆

Journal of Integrative Plant Biology 2009年第1期51卷 29-34页

作者： Cheng-he Zhang Xiao-Feng Li shu-xing Shen he Yuan shu-xin Xuan College of Horticulture Agncultural University of Hebei Baoding 071001 China

A set of trisomics of Chinese cabbage was used for determining the n-I-1 gamete transmission rate and locating the gene controlling 2n gamete formation on the corresponding chromosome. The results showed that the transmission rates of extra chromosomes in different trisomics varied from 0% to 15.38% by male gametes and from 0% to 17.39% by female gametes. Of the nine F2 populations derived from the hybridizations between each trisomic and Bp058 （2n gamete material）, only Tri- 4xBp058 showed that the segregation ratio of plants without 2n gamete formation to plants with 2n gamete formation was 10.38：1, which fitted the expected segregation ratio of the trisomics （AAa） based on the 7.37% of n＋l gamete transmission through female and 5.88% through male. In other populations the segregation ratios varied from 2.48：1 to 3.72：1, which fitted the expected 3：1 segregation ratio of the bisomics （Aa）. These results suggested that the gene controlling 2n gamete formation in Chinese cabbage Bp058 was located on chromosome 4. Further trisomic analysis based on the chromosome segregation and the incomplete stochastic chromatid segregation indicated that the gene locus was tightly linked to the centromere.

关键词： Chinese cabbage gene location n+l gamete transmission primary trisomics 2n gametes.

Monosomic Addition Lines of Flowering Chinese Cabbage(*** *** *** ***)-Chinese Kale(*** *** ***)

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Agricultural Sciences in China 2008年第6期7卷 656-663页

作者： WANG xin-e ZHANG Cheng-he XUAN shu-xin MAN Hong LIU Hai-he SheN shu-xing College of Horticulture Agricultural University of Hebei Baoding 071001 P.R.China

Interspecific alien addition lines have played significant roles in gene mapping, intergenomic gene transfer and chromosomal homoeological identification between closely related species. Selection of alien addition lines was conducted by karyotype analysis and morphological observation with the reference of parents. Triploid interspecies hybrid （AAC, 2n = 3x = 29） was obtained from Brassica campestris ssp. chinensis var. parachinensis Qinglu 9601 （tetraploid, AAAA, 2n = 4x = 40） x B. oleracea var. alboglabra Baihua 9705 （diploid, CC, 2n = 2x = 18） by immature hybrid embryo culture in vitro. Five different alien monosomic addition lines （AA ＋ C2, AA ＋ C3, AA ＋ C4, AA ＋ C6, AA ＋ C7） were obtained from the backcross progenies of AAC x AA. Each alien monosomic addition line has some specific morphological characters. It is feasible to obtain alien addition lines from the progenies of AAC × AA by karyotype analysis and morphological observation based on the reference of parents

关键词： flowering Chinese cabbage Chinese kale allotriploid alien addition lines

Coronavirus Disease 2019 versus Influenza A in Children: An Observational Control Study in China

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Biomedical and Environmental Sciences 2020年第8期33卷 614-619页

作者： ZHAO Yang SUN De Lin heather CBouchard ZHANG xin xin WAN Gang HAO Yi Wei he shu xin JIANG Yu Yong PANG Lin Department of Pediatrics Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Brain Imaging and Analysis Center Duke UniversityDurham 20075North CarolinaUSA Department of Party Committee Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Department of Medical Records Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China

This study aimed to understand the differences in clinical,epidemiological,and laboratory features between the new coronavirus disease 2019(COVID-2019)and influenza A in *** of 23 hospitalized children with COVID-19(9 boys,5.7±3.8 years old)were compared with age-and sexmatched 69 hospitalized and 69 outpatient children with influenza A from a hospital in China.

关键词： Observation clinical matched

Studies on the Formation and Transmission of n + 1 Gametes of Cabbage Primary Trisomics

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Agricultural Sciences in China 2007年第7期6卷 786-791页

作者： ZHANG Cheng-he XUAN shu-xin ZHU Hai-yan SheN shu-xing MAN Hong College of Horticulture Agricultural University of Hebei Baoding 071001 P.R. China

The transmission rate of n ＋ 1 gamete is an important parameter for the genetic analysis of trisomics. To correctly use the trisomics of the cabbage to carry out gene orientation and other genetic studies, the n ＋ 1 gamete transmission rates by female parent and by male parent were determined. The results showed that the n ＋ 1 gamete transmission rates were 15.28% for tri-1, 12.68% for tri-2, 12.31% for tri-3, 30.51% for tri-4, 22.81% for tri-5, 7.46% for tri-6, 5.36% for tri-7, 42.37% for tri-8, and 9.23% for tri-9 by female parent, and were 12.12% for tri-1, 12.33% for tri-2, 7.81% for tri-3, 4.76% for tri-4, 8.93% for tri-5, 10.94% for tri-6, 1.54% for tri-7, 2.94% for tri-8, and 13.04% for tri-9 by male parent. The main factors affecting the male n ＋ 1 gamete formation and transmission were the rate of trivalent formation at prophase Ⅰ, the rate of 9-9-10-10 division at anaphase Ⅱ, and the pollen viability.

关键词： cabbage primary trisomics N + 1 gametes transmission rate

Involvment of BNIP3 in the antidepressant’s effects on the hippocampal neuroplasticity

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Involvment of BNIP3 in the antidepressant’s effects on the ...

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： xin-Hua he,shu-Ji LI,xin-Hong ZHU,Tian-Ming GAO~* Department of Neurobiology,College of Basic Medical Sciences,Southern Medical University,Guangzhou 510515, China

＜正＞Objective Depression is a common mental disorder with high prevalence,high disability rate and high suicide rate,and severely impairs human lives and *** studies have shown that depression has a close relationship with abnormal hippocampal *** this process is thought to be a new strategy for rapid *** the key moleculars that regulate this kind of hippocampal neuroplasticity is expected to find candidate targets for ***,little is known about the molecular mechanism for antidepressants regulating *** present research aimed at exploring whether Bcl-2/adenovirus E1B 19 kD-interacting protein 3（BNIP3） participates in antidepression by regulating the hippocampal neuroplasticity,providing experimental evidences for finding candidate and rapid antidepressant targets for depression *** The expression of BNIP3 is quantified by real-time PCR and western blot during the key period of the development of the dendrite, spine and synapse formation of hippocampal *** of BNIP3 and RNA interference methods were used to determine the influence of BNIP3 on dendrite arbors of hippocampal *** real-time PCR and western blot methods to quantify the exprEssion of BNIP3,synapsinl and GluRI after the administration of imipramine and ***（1） BNIP3 continued to increase during the critical period of the dendrite,spine and synapse formation of hippocampal neuron in culture.（2） Antidepressants imipramine and fluoxetine could increase the expression of BNIP3,synapsinl and GluRI in hippocampal neuron.（3） Overexpression of BNIP3 increased the number of dendrite arbors of hippocampal neuron,while BNIP3 siRNA has no influence on the number of dendrite arbors of hippocampal *** BNIP3 may participate in the antidepressant’s effects on the hippocampal neuroplasticity.

关键词： BNIP3 depression neuroplasticity hippocampus

来源： cnki会议评论

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试论结构隐喻的系统性与篇章连贯

海外英语 2016年第3期 190-191页

作者：何心舒深圳信息职业技术学院应用外语学院广东深圳518029

结构隐喻是概念隐喻的一种,该系统性可分为结构隐喻内部系统性及结构隐喻之间的系统性。作为心智模型,结构隐喻通过隐喻内部系统性形成的系统的隐喻蕴涵建构篇章连贯。源于同一本体的结构隐喻可以通过同一话题(隐喻本体)或者重叠隐喻蕴... 详细信息

结构隐喻是概念隐喻的一种,该系统性可分为结构隐喻内部系统性及结构隐喻之间的系统性。作为心智模型,结构隐喻通过隐喻内部系统性形成的系统的隐喻蕴涵建构篇章连贯。源于同一本体的结构隐喻可以通过同一话题(隐喻本体)或者重叠隐喻蕴涵构建篇章连贯。

关键词：结构隐喻系统性连贯

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皖西学院学生读者工具书阅览状况统计分析

大学图书情报学刊 2006年第2期24卷 64-67,75页

作者：舒和新皖西学院六安237012

通过对皖西学院学生读者工具书阅览状况的统计分析可以发现,工具书的读者比较少,但利用率比较高,不同种类工具书的利用率有所差别,学生的非专业性阅览多于专业性阅览,其阅读类型也各有不同。统计数据还反映出图书馆工作和学生学习生活... 详细信息

通过对皖西学院学生读者工具书阅览状况的统计分析可以发现,工具书的读者比较少,但利用率比较高,不同种类工具书的利用率有所差别,学生的非专业性阅览多于专业性阅览,其阅读类型也各有不同。统计数据还反映出图书馆工作和学生学习生活中存在的问题。

关键词：皖西学院工具书学生读者阅览状况

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从方舱数字图书馆看农民工数字图书馆的建设

福建图书馆学刊 2021年第3期4卷 63-67页

作者：舒和新皖西学院图书馆安徽六安237012

方舱数字图书馆具有资源量大、针对性强、成本低的特点,是一种服务方式创新,具有重要示范意义和推广价值。农民工是一个数量庞大的特殊群体,为我国城市建设作出了巨大贡献,同时他们需要提升和丰富自己,需要社会各方面的关心和帮助。各... 详细信息

方舱数字图书馆具有资源量大、针对性强、成本低的特点,是一种服务方式创新,具有重要示范意义和推广价值。农民工是一个数量庞大的特殊群体,为我国城市建设作出了巨大贡献,同时他们需要提升和丰富自己,需要社会各方面的关心和帮助。各级公共图书馆可仿照方舱数字图书馆的模式建设农民工数字图书馆,农民工数字图书馆应该包含农民工生活类、学习类和休闲类资源。

关键词：方舱数字图书馆农民工数字图书馆定向服务数字资源

维普期刊数据库评论

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维普期刊数据库

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建本文化研究中的几个问题

福建图书馆学刊 2018年第3期1卷 49-50,34页

作者：舒和新皖西学院图书馆安徽六安237012

建本文化是一种历史现象,对建本的评价要有历史的视角。笔者认为,建本应该是指建安刻书;建本兴起的根本原因是雕版印刷技术成熟并广泛传播。建本文献虽然存在一些质量问题,但对中国古代知识和文化的传播发挥了重要作用。

关键词：建本文化建安刻书建阳刻书雕版印刷

多基因遗传风险评分(PRS)在遗传疾病研究中的应用与前景:数据分析方法综述

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生物化学与生物物理进展 2024年第8期51卷 1797-1808页

作者：贺舒欣喻长顺贾晓冬陈建春闫克强天津金域医学检验实验室天津300392 天津市神经系统疾病多组学精准诊断技术重点实验室天津300392

多基因遗传风险评分(polygenic risk score,PRS)是一种新兴的遗传数据分析方法。该方法通过对个体多个遗传变异位点的综合考虑,对个体复杂疾病的遗传风险进行定量评估,在遗传学领域受到广泛关注,同时该方法的有效性也在临床应用中得到... 详细信息

多基因遗传风险评分(polygenic risk score,PRS)是一种新兴的遗传数据分析方法。该方法通过对个体多个遗传变异位点的综合考虑,对个体复杂疾病的遗传风险进行定量评估,在遗传学领域受到广泛关注,同时该方法的有效性也在临床应用中得到进一步验证。由于PRS的计算涉及大量的基因组数据分析,其模型的数据选择、构建方法以及验证方法均存在较大差异。本综述结合目前已发表的PRS相关研究和算法,对PRS模型以及其应用进行阐述。

关键词：多基因遗传风险评分全基因组关联研究遗传学复杂疾病