检索结果-南通市图书馆

Acute exposure to high-peak-power pulsed microwaves affecting the histamine H_3 receptor expression in rat hippocampus

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2006年第4期17卷 227-231页

作者： YU Xiao-Dong LI Bo LI De-Hua he qi-yi YU Zheng-Ping Department of Occupational health School of Preventive Medicine Third Military. Medical University Chongqing 400038China Chongqing Key Laboratory of Animal Sciences School of Biological Science Chongqing Normal University Chongqing 400037 China

In the Morris Water Maze test, high-peak-power pulsed microwave (MW)-exposed rats displayed some learning and memory behavior dysfunctions, and their escape time and swimming distance to the submerged platform were longer than those of the sham-exposed rats. To understand the molecular mechanism involved, the reverse tran- scription-polymerase chain reaction (RT-PCR) and the Western-blotting technique were used for investigating the mRNA and protein expression patterns of the histamine H3 receptor (H3R) in rat hippocampus. High-peak-power pulsed microwave-exposure did not remarkably lead to the change in expression of H3R mRNA in rat hippocampi; however, it promoted the up-regulatory expression of the H3R protein, which was possibly triggered through the mi- togen-activated protein kinase (MAPK) pathways. Therefore, further investigation of the molecular mechanism of the MW effects on the learning and memory behaviors is required.

关键词：组胺H3受体大鼠海马微波辐照表达

Exploring hidden-charm and hidden-strange hexaquark states from lattice QCD

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第1期67卷 30-37页

作者： Hang Liu Jinchen he Liuming Liu Peng Sun Wei Wang yi-Bo Yang qi-An Zhang INPAC Key Laboratory for Particle Astrophysics and Cosmology(MOE)Shanghai Key Laboratory for Particle Physics and CosmologySchool of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China Maryland Center for Fundamental Physics Department of PhysicsUniversity of MarylandCollege ParkMaryland 20742USA Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China Department of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing 210023China Southern Center for Nuclear-Science Theory(SCNT) Institute of Modern PhysicsChinese Academy of SciencesHuizhou 516000China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUCASHangzhou 310024China International Centre for Theoretical Physics Asia-Pacific Beijing 100049/Hangzhou 310024China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Physics Beihang UniversityBeijing 102206China

Based on five different ensembles of newly generated(2+1)-flavor configurations with pion mass of approximately mπ■(140-310)MeV,we present a lattice analysis of hidden-charm and hidden-strange hexaquarks with the quark content■.The correlation matrices of two types of operators with JPC=0++,0-+,1++and 1--are simulated to extract the masses of the hexaquark candidates,which are subsequently extrapolated to the physical pion mass and continuum *** results indicate that ground state masses are below the■threshold and provide a characteristic signal for the experimental discovery of hexaquark candidates,which may enrich the versatile structure of multiquarks;moreover,it is an indispensable step to decipher the nonperturbative nature of the fundamental interactions of quarks and gluons.

关键词： quantum chromodynamics lattice QCD multiquark states

High-Efficiency Dynamic Scanning Strategy for Powder Bed Fusion by Controlling Temperature Field of the heat-Affected Zone

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2024年第1期37卷 203-214页

作者： Xiaokang Huang Xiaoyong Tian qi Zhong Shunwen he Cunbao Huo yi Cao Zhiqiang Tong Dichen Li State Key Laboratory of Manufacturing Systems Engineering Xi’an Jiaotong UniversityXian 710049China

Improvement of fabrication efficiency and part performance was the main challenge for the large-scale powder bed fusion(PBF)*** this study,a dynamic monitoring and feedback system of powder bed temperature field using an infrared thermal imager has been established and integrated into a four-laser PBF equipment with a working area of 2000 mm×2000 *** heat-affected zone(HAZ)temperature field has been controlled by adjusting the scanning speed ***,the relationship among spot size,HAZ temperature,and part performance has been *** fluctuation of the HAZ temperature in four-laser scanning areas was decreased from 30.85℃to 17.41℃.Thus,the consistency of the sintering performance of the produced large component has been *** on the controllable temperature field,a dynamically adjusting strategy for laser spot size was proposed,by which the fabrication efficiency was improved up to 65.38%.The current research results were of great significance to the further industrial applications of large-scale PBF equipment.

关键词： Powder bed fusion Efficiency Large-scale Spot size heat-affected zone(HAZ)

Oral delivery of insulin by barbed microneedles actuated by intestinal peristalsis

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第9期35卷 6-8页

作者： qin Yu Haisheng he Jianping qi yi Lu Wei Wu Shanghai Skin Disease Hospital Tongji University School of MedicineShanghai 200443China Key Laboratory of Smart Drug Delivery of MOE School of PharmacyFudan UniversityShanghai 201203China

Oral formulations are always preferred to injections due to the advantages of high patient compliance,no biohazardous needle waste,and low requirements for administration ***,the presence of multiple gastrointestinal(GI)barriers,including extreme gastric acidity and a broad pH gradient,digestive enzymes,thick and variable mucus layers,and tight junctions in the enteric epithelia,restricts the rate and extent of oral *** active ingredients with favorable physicochemical properties.

关键词： needle extreme formulation

The size effect and analogous boundary states in a circular non-hermitian chain

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2024年第2期76卷 157-165页

作者： Xin-Yu Ma yi-Han Guan qiao-Nan Li Ai-Lei he Lu qi School of Physical Science and Technology Yangzhou UniversityYangzhou 225002China

We investigate the size effect and boundary states based on a circular non-hermitian chain under the nonreciprocal intra-cell coupling and inter-cell coupling *** find that the circular non-hermitian chain exhibits an even–odd effect on the unit cell corresponding to a large chain,which is different from the open non-hermitian chain only exhibiting the same effect for a small ***,we find that the originally localized bulk states become totally extended via designing the boundary coupling strength *** extended bulk states reveal the fact of the disappearance of the non-hermitian skin *** particular,we show that the circular non-hermitian chain also possesses the analogous edge states under some parameter regimes,which is pretty counterintuitive since the circular chain usually cannot define a *** investigations supply the different non-hermitian phenomena in a circular non-hermitian chain.

关键词： boundary states non-hermitian chain topological state

Boson star superradiance

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 69-78页

作者： he-Yu Gao Paul M.Saffin yi-Jie Wang qi-Xin Xie Shuang-Yong Zhou School of Physical Sciences University of Science and Technology of ChinaHefei 230026China School of Physics and Astronomy University of NottinghamUniversity ParkNottingham NG72RDUK Interdisciplinary Center for Theoretical Study University of Science and Technology of ChinaHefei 230026China Peng Huanwu Center for Fundamental Theory Hefei 230026China

Recently,it has been realized that in some systems internal space rotation can induce energy amplification for scattered waves,similar to rotation in real *** particularly,it has been shown that energy extraction is possible for a Q-ball,a stationary non-topological soliton that is coherently rotating in its field *** this paper,we generalize the analysis to the case of boson stars,and show that the same energy extraction mechanism still works for boson stars.

关键词： superradiance boson star field space rotation

Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第5期40卷 776-785页

作者： qi yi FAN Hailong Department of Neurosurgery Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo060-8638Japan Institute for Chemical Reaction Design and Discovery(WPI-ICReDD) Hokkaido UniversitySapporo001-0021Japan

Vascular embolization treatment,a minimally invasive surgery for various blood vessel-related conditions,has emerged as a crucial method in treating such as hemorrhage,arteriovenous malformation,aneurysms,and hypervascular *** embolic agents are gaining prominence due to their distinct advantage in infiltrating distal regions,expanding the scope of embolization beyond the reach of solid *** strides in biomaterials and technologies have spurred the development of novel liquid embolic agents,addressing challenges posed by traditional *** mini-review provides a concise overview of the recent progress in water-based liquid embolic agents,highlighting their potential to overcome limitations associated with current embolic *** presenting selected research outcomes,we illuminate advancements that enhance the efficacy of liquid embolic ***,the review outlines essential properties for effective liquid embolic agents,offering insights for future developments in this field.

关键词： Endovascular treatment Lquid embolic agent Hydrogel

Highly Conductive Ag/pCF/MVQ Composite Rubber for Efficient Electromagnetic Interference Shielding

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第6期42卷 864-873页

作者： Yang Chen Xiao-Ming Shao Liang he yi-Nuo Xu qi-Yuan Yao Ding Feng Wen-Cai Wang State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing100029China Key Laboratory of Beijing City for Preparation and Processing of Novel Polymer Materials Beijing University of Chemical TechnologyBeijing100029China Sino-german School of Engineering Qingdao University of Science and TechnologyQingdao266400China

In this study,flexible and highly conductive composite rubber at low filler content was successfully prepared through polydopamine-assisted electroless silver plating plus mechanical ***,carbon fibers(CF)were activated by polydopamine(PDA)to improve the surface activity by self-polymerization ***,because of the metal chelating ability of PDA,silver layer was firmly deposited on the surface of CF through a facile electroless silver plating ***,flexible silver-plated carbon fibers(Ag/pCF)silicone rubber composites prepared by mechanical *** using X-ray photoelectron spectroscopy(XPS)and X-ray diffraction(XRD),the chemical composition and crystal structure of Ag/pCF were examined,and scanning electron microscopy(SEM)was used to assess the surface morphology of the Ag/*** results showed that a uniform and dense silver layer was formed on the surface of the CF,and the conductivity of the Ag/pCF could reach 7885 S/*** was noteworthy that the composite rubber filled with only 45 phr Ag/pCF had a high electromagnetic interference shielding effectiveness(100 dB)due to the low density and high aspect ratio of Ag/*** composite rubber has excellent potential for application in the field of electromagnetic interference shielding.

关键词： Carbon fibers Polydopamine Electroless plating Silver Electromagnetic interference shielding

Establishing Modular Cell-Free Expression System for the Biosynthesis of Bicyclomycin from a Chemically Synthesized Cyclodipeptide

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第4期42卷 384-390页

作者： yi-Pei Liu Yu-heng Zhao Wen-qi Zhang Lian Wu Linjuan Huang Gong-Li Tang Jun-Bin he Shaanxi Natural Carbohydrate Resource Engineering Research Center College of Food Science and TechnologyNorthwest UniversityXi'anShaanxi710069 China State Key Laboratory of Chemical Biology Shanghai Institute of Organic ChemistryUniversity of Chinese Academy of Sciences(CAS)CASShanghai200032 China School of Chemistry and Materials Science Hangzhou Institute for Advanced StudyUniversity of CAS1 Sub-lane XiangshanHangzhouZhejiang310024 China

Cell-free expression systems have emerged as a versatile and powerful platform for metabolic engineering,biosynthesis and synthetic biology ***,successful examples of the synthesis of complex natural products using this system are still ***,a structurally unique and complex diketopiperazine alkaloid,is a clinically promising antibiotic that selectively inhibits the transcription termination factor ***,we established a modular cell-free expression system with cascade catalysis for the biosynthesis of bicyclomycin from a chemically synthesized *** six cell-free expressed biosynthetic enzymes,including five iron-andα-ketoglutarate-dependent dioxygenases and one cytochrome P450 monooxygenase,were active in converting their substrates to the corresponding *** co-expressed enzymes in the cell-free module were able to complete the related partial *** vitro biosynthesis of bicyclomycin was also achieved by reconstituting the entire biosynthetic pathways(i.e.,six enzymes)using the modular cell-free expression *** study demonstrates that the modular cell-free expression system can be used as a robust and promising platformforthe biosynthesis of complex antibiotics.

关键词： Natural products Bicyclomycin Biosynthesis Iron-andα-ketoglutarate-dependent dioxygenases Cytochrome P450 monooxygenase Cell-freeprotein synthesis Enzyme catalysis