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缺血性卒中后抑郁动物模型中医病证研究进展

广州中医药大学学报 2024年第7期41卷 1926-1930页

作者：何洁莹杨月廖亮英湖南中医药大学第一附属医院湖南长沙410007

缺血性卒中后抑郁(post-ischemic stroke depression)是脑血管病变常见的并发症。该文对国内近年来缺血性卒中后抑郁造模方法及其模型评估、缺血性卒中后抑郁中医病证结合动物模型造模方法的研究进展进行综述,以期为拓展中医疗法的临床... 详细信息

缺血性卒中后抑郁(post-ischemic stroke depression)是脑血管病变常见的并发症。该文对国内近年来缺血性卒中后抑郁造模方法及其模型评估、缺血性卒中后抑郁中医病证结合动物模型造模方法的研究进展进行综述,以期为拓展中医疗法的临床应用及开展其疗效机制的研究提供基础。缺血性卒中后抑郁模型多采用脑卒中模型合并郁证的方法造模,主要有线栓法结扎颈内动脉联合慢性不可预见性温和应激(chronic unpredictable mild stress,CUMS)及孤养法,线栓法结扎左颈内动脉、右颈外动脉和左右椎动脉联合孤养及束缚应激法,以及线栓法结扎一侧颈总动脉联合可预见刺激及孤养法。缺血性卒中后抑郁中医病证结合动物模型涉及肝气郁滞证、气虚血瘀证、痰蒙神窍证、肾虚证的缺血性卒中后抑郁动物模型的制备。目前建立的缺血性卒中后抑郁中医病证结合动物模型,虽具备西医病理表现和中医证候的病症特征,但是否能反映临床患者的病证结合本质,仍有待研究。

关键词：缺血性脑卒中后抑郁动物模型中医病证结合肝气郁滞证气虚血瘀证痰蒙神窍证肾虚证综述

EFFECTS OF A CLOUD FILTERING METHOD FOR FENGYUN-3C MICROWAVE HUMIDITY AND TEMPERATURE SOUNDER MEASUREMENTS OVER OCEAN ON RETRIEVALS OF TEMPERATURE AND HUMIDITY

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Journal of Tropical Meteorology 2018年第1期24卷 29-41页

作者： he Qiu-rui WANG Zhen-zhan he jie-ying Key Laboratory of Microwave Remote Sensing National Space Science CenterChinese Academy of SciencesBeijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China

For Microwave Humidity and Temperature sounder(MWHTS) measurements over the ocean, a cloud filtering method is presented to filter out cloud-and precipitation-affected observations by analyzing the sensitivity of the simulated brightness temperatures of MWHTS to cloud liquid water, and using the root mean square error(RMSE)between observation and simulation in clear sky as a reference standard. The atmospheric temperature and humidity profiles are retrieved using MWHTS measurements with and without filtering by multiple linear regression(MLR),artificial neural networks(ANN) and one-dimensional variational(1DVAR) retrieval methods, respectively, and the effects of the filtering method on the retrieval accuracies are analyzed. The numerical results show that the filtering method can improve the retrieval accuracies of the MLR and the 1DVAR retrieval methods, but have little influence on that of the ANN. In addition, the dependencies of the retrieval methods upon the testing samples of brightness temperature are studied, and the results show that the 1DVAR retrieval method has great stability due to that the testing samples have great impact on the retrieval accuracies of the MLR and the ANN, but have little impact on that of the 1DVAR.

关键词： FY-3C/MWHTS cloud filtering method multiple linear regression artificial neural networks one-dimensional variational retrieval

A COMPARISON OF The RETRIEVAL OF ATMOSPheRIC TEMPERATURE PROFILES USING OBSERVATIONS OF The 60 GHZ AND 118.75 GHZ ABSORPTION LINES

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Journal of Tropical Meteorology 2018年第2期24卷 151-162页

作者： he Qiu-rui WANG Zhen-zhan he jie-ying ZHANG Lan-jie Key Laboratory of Microwave Remote Sensing National Space Science Center Chinese Academy of SciencesBeijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China

The Microwave Temperature Sounder-Ⅱ(MWTS-Ⅱ) and Microwave Humidity and Temperature Sounder(MWHTS) onboard the Fengyun-3 C(FY-3 C) satellite can be used to detect atmospheric temperature profiles. The MWTS-II has 13 temperature sounding channels around the 60 GHz oxygen absorption band and the MWHTS has 8 temperature sounding channels around the 118.75 GHz oxygen absorption line. The data quality of the observed brightness temperatures can be evaluated using atmospheric temperature retrievals from the MWTS-Ⅱ and MWHTS observations. here, the bias characteristics and corrections of the observed brightness temperatures are described. The information contents of observations are calculated, and the retrieved atmospheric temperature profiles are compared using a neural network(NN) retrieval algorithm and a one-dimensional variational inversion(1 D-var) retrieval algorithm. The retrieval results from the NN algorithm show that the accuracy of the MWTS-Ⅱ retrieval is higher than that of the MWHTS retrieval, which is consistent with the results of the radiometric information analysis. The retrieval results from the 1 D-var algorithm show that the accuracy of MWTS-Ⅱ retrieval is similar to that of the MWHTS retrieval at the levels from 850-1,000 h Pa, is lower than that of the MWHTS retrieval at the levels from 650-850 h Pa and 125-300 h Pa, and is higher than that of MWHTS at the other levels. A comparison of the retrieved atmospheric temperature using these satellite observations provides a reference value for assessing the accuracy of atmospheric temperature detection at the 60 GHz oxygen band and 118.75 GHz oxygen line. In addition, based on the comparison of the retrieval results, an optimized combination method is proposed using a branch and bound algorithm for the NN retrieval algorithm, which combines the observations from both the MWTS-Ⅱand MWHTS instruments to retrieve the atmospheric temperature profiles. The results show that the optimal combination can further i

关键词： Fengyun-3C satellite Microwave Temperature Sounder-II microwave humidity and temperature sounder one-dimensional variational retrieval algorithm neural networks retrieval algorithm

Distributed Nash Equilibrium Seeking on Compact Action Sets over Jointly Strongly Connected Switching Networks

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Journal of Systems Science & Complexity 2024年第1期37卷 63-81页

作者： he Xiongnan HUANG jie Department of Mechanical and Automation Engineering The Chinese University of Hong KongHong Kong 999077China.

This paper studies the distributed Nash equilibrium seeking(DNES)problem for games whose action sets are compact and whose network graph is switching satisfying the jointly strongly connected *** keep the actions of all players in their action sets all the time,one has to resort to the projected gradient-based *** the assumption that the unique Nash equilibrium is the unique equilibrium of the pseudogradient system,an algorithm is proposed that is able to exponentially find the Nash ***,the authors also consider the distributed Nash equilibrium seeking problem for games whose actions are governed by high-order integrator dynamics and belong to some compact *** examples are used to illustrate the proposed approach.

关键词： Compact action sets jointly strongly connected switching graphs Nash equilibrium seeking projected gradient-based algorithm.

Synthesis and applications of Ag@C composites:Progress and opportunity

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Journal of Central South University 2022年第11期29卷 3503-3528页

作者： he ying-jie ISSAKA Alhassan Sikpaan YAN Lyu-ji CAO Yi-yun GANG Hai-yin WU Bi-chao JIN Lin-feng WANG Hai-ying School of Metallurgy and Environment Central South UniversityChangsha 410083China Chinese National Engineering Research Center for Control and Treatment of heavy Metal Pollution Changsha 410083China School of Materials Science and Engineering Central South UniversityChangsha 410083China

Developing classes of Ag@C composites stand out for their one of a kind structure and novel physicochemical properties in later a long *** review explores the current state-of-the-art progress in the preparation methods and the novel properties of Ag@C *** provide a definition of the stability of Ag@C composites,and propose strategies to improve the *** on the later inquire,a summary and outlook toward the synthesis and applications of Ag@C composites are presented,aiming to accelerate the exploration of Ag@C composites and further stimulate the applications in various fields.

关键词： Ag@C composites synthesis application interfacial interaction

Distribution and correlation of refractive parameters in children with different corneal curvatures in southeast China

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 713-720页

作者： Si-Yuan he Ting he Meng-Yue Xu ying-jie Ni Chao-Yang Hong Ting Shen The Second Clinical College Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Ophthalmology Zhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhou 310014Zhejiang ProvinceChina Eye Center the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina

AIM:To analyze the distribution of refractive status in school-age children with different corneal curvatures(CC)and the correlation between CC and refractive ***:A total of 2214 school-aged children of grade 4 in Hangzhou who were screened for school myopia were *** distance visual acuity(UCDVA),non-cycloplegic refraction,axial length(AL),horizontal and vertical corneal curvature(K1,K2)were measured and spherical equivalent(SE),corneal curvature radius(CCR)and axial length/corneal radius of curvature ratio(AL/CR)were ***he different CCRs,the patients were divided into the lower corneal curvature(LCC)group(CCR≥7.92)and the higher corneal curvature(HCC)group(CCRher divided into the normal AL subgroup and the long AL *** refractive parameters were compared to identify any differences between the two ***:Both SE and AL were greater in the LCC group(P=0.013,Phe prevalence of myopia was 38% in the LCC group and 44% in the HCC group(Phe proportion of children without screening myopia was higher in the LCC group(62%)than in the HCC group(56%).Among these children without screening myopia,the proportion of long AL in the LCC group(24%)was significantly higher than that in the HCC group(0.012%;Phe change of SE in the LCC group was less affected by the increase of AL than that in the HCC ***:School-aged children in the LCC group have a lower incidence of screening myopia and longer *** CC can mask SE reduction and AL growth to some extent,and the change of AL growth change more in children with low CC than high *** the onset of myopia,its growth rate is even faster than that after the onset of myopia.

关键词： school-aged children corneal curvature axial length spherical equivalent myopia screening

Coupled Numerical Simulation of Electromagnetic and Flow Fields in a Magnetohydrodynamic Induction Pump

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Fluid Dynamics & Materials Processing 2024年第4期20卷 889-899页

作者： he Wang ying he College of Transportation Ludong UniversityYantai264025China College of Intelligent Manufacturing City College of HuizhouHuizhou516025China

Magnetohydrodynamic(MHD)induction pumps are contactless pumps able to withstand harsh *** rate of fluid flow through the pump directly affects the efficiency and stability of the *** explore the influence of induction pump settings on the related delivery speed,in this study,a numerical model for coupled electromagnetic and flow field effects is introduced and used to simulate liquid metal lithium flow in the induction *** effects of current intensity,frequency,coil turns and coil winding size on the velocity of the working fluid are *** is shown that the first three parameters have a significant impact,while changes in the coil turns have a negligible *** maximum increase in working fluid velocity within the pump for the parameter combination investigated in this paper is approximately 618%.As the frequency is increased from 20 to 60 Hz,the maximum increase in the mean flow rate of the working fluid is approximately 241%.These research findings are intended to support the design and optimization of these devices.

关键词： Magnetic fluid multi-physical field coupling induction pump numerical simulation liquid metal conveying

Neural Stem Cell Competition

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Neuroscience Bulletin 2024年第2期40卷 277-279页

作者： Yanan Li jie he State Key Laboratory of Neuroscience Institute of NeuroscienceCenter for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai 200031China University of Chinese Academy of Sciences Beijing 100049China

Cell competition is an adaptive surveillance mechanism to ensure the robustness of developmental outputs,maintain tissue integrity,and regulate tumor progression in multicellular organisms,which is highly conserved from invertebrates to vertebrates[1].At the cellular level,cell competition represents a non-cell-autonomous process in that cells can sense the fitness of their neighbors through cellular interactions,thereby eliminating low-fitness cells and expanding high-fitness counterparts,however,cells develop normally in homogenous populations.

关键词： thereby maintain eliminating

Hierarchical vectorization for facial images

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Computational Visual Media 2024年第1期10卷 97-118页

作者： Qian Fu Linlin Liu Fei Hou ying he School of Computer Science and Engineering Nanyang Technological University639798SingaporeSingapore Data61 Commonwealth Scientific and Industrial Research OrganisationSydney2015Australia Interdisciplinary Graduate School Nanyang Technological University and Alibaba Group639798SingaporeSingapore State Key Laboratory of Computer Science Institute of SoftwareChinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China

The explosive growth of social media means portrait editing and retouching are in high *** portraits are commonly captured and stored as raster images,editing raster images is non-trivial and requires the user to be highly *** at developing intuitive and easy-to-use portrait editing tools,we propose a novel vectorization method that can automatically convert raster images into a 3-tier hierarchical *** base layer consists of a set of sparse diffusion curves(DCs)which characterize salient geometric features and low-frequency colors,providing a means for semantic color transfer and facial expression *** middle level encodes specular highlights and shadows as large,editable Poisson regions(PRs)and allows the user to directly adjust illumination by tuning the strength and changing the shapes of *** top level contains two types of pixel-sized PRs for high-frequency residuals and fine details such as pimples and *** train a deep generative model that can produce high-frequency residuals *** to the inherent meaning in vector primitives,editing portraits becomes easy and *** particular,our method supports color transfer,facial expression editing,highlight and shadow editing,and automatic *** quantitatively evaluate the results,we extend the commonly used FLIP metric(which measures color and feature differences between two images)to consider *** new metric,illumination-sensitive FLIP,can effectively capture salient changes in color transfer results,and is more consistent with human perception than FLIP and other quality measures for portrait *** evaluate our method on the FFHQR dataset and show it to be effective for common portrait editing tasks,such as retouching,light editing,color transfer,and expression editing.

关键词： face editing vectorization Poisson editing color transfer illumination editing expression editing