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血管内支架技术治疗颅内椎动脉动脉瘤

中国医学影像技术 2005年第3期21卷 450-452页

作者：刘爱华吴中学李佑祥张静波姜除寒杨新健首都医科大学北京市神经外科研究所神经介入科北京100050

目的探讨血管内支架技术在颅内椎动脉动脉瘤的应用价值.方法回顾性分析18例采用支架治疗的颅内椎动脉动脉瘤,其中椎动脉梭形动脉瘤10例,全部一期支架结合弹簧圈技术治疗;椎动脉夹层动脉瘤8例,单纯支架技术4例,支架技术二期联合弹簧圈技... 详细信息

目的探讨血管内支架技术在颅内椎动脉动脉瘤的应用价值.方法回顾性分析18例采用支架治疗的颅内椎动脉动脉瘤,其中椎动脉梭形动脉瘤10例,全部一期支架结合弹簧圈技术治疗;椎动脉夹层动脉瘤8例,单纯支架技术4例,支架技术二期联合弹簧圈技术治疗4例.结果 16例造影随访3～24个月全部治愈,无复发及狭窄.2例术后出现一过性脑缺血的表现.结论在治疗椎动脉梭形及夹层动脉瘤时应区别对待,血管内支架辅助GDC技术可保持载瘤动脉通畅,是一种安全、有效的选择.

关键词：血管内支架椎动脉梭形动脉瘤夹层动脉瘤弹簧圈

Insight-HXMT observations of the first binary neutron star merger GW170817

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Science China(Physics,Mechanics & Astronomy) 2018年第3期61卷 26-33页

作者： TiPei li Shaolin Xiong ShuangNan Zhang FangJun Lu liMing Song xueLei Cao Zhi Chang Gang Chen li Chen Tianxiang Chen Yong Chen YiBao Chen YuPeng Chen wei Cui weiwei Cui JingKang Deng Yongwei Dong YuanYuan Du Minxue Fu GuanHua Gao he Gao Min Gao MingYu Ge YuDong Gu Ju Guan chengcheng Guo Dawei han wei Hu Yue Huang Jia Huo ShuMei Jia LuHua jiang weichun jiang Jing Jin YongJie Jin Bing li chengKui li Gang li MaoShun li wei li Xian li XiaoBo li XuFang li YanGuo li ZiJian li Zhengwei li XiaoHua liang JinYuan liao CongZhan liu GuoQing liu hongwei liu ShaoZhen liu XiaoJing liu Yuan liu YiNong liu Bo Lu xueFeng Lu Tao Luo xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai liang Sun Yin Tan lian Tao WenHui Tao youli Tuo GuoFeng wang HuanYu wang Juan wang WenShuai wang YuSa wang xiangYang Wen BoBing wu Mei wu Guangcheng Xiao he Xu YuPeng Xu linli Yan Jiawei Yang Sheng Yang YanJi Yang AiMei Zhang chunLei Zhang chengMo Zhang Fan Zhang hongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang Ziliang Zhang HaiSheng Zhao Jianling Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu Changlin Zou Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China Department of Physics Tsinghua University Beijing 100084 China University of Chinese Academy of Sciences Chinese Academy of Sciences Beijing 100049 China Department of Astronomy Beijing Normal University Beijing 100088 China Department of Engineering Physics Tsinghua University Beijing 100084 China

Finding the electromagnetic （EM） counterpart of binary compact star merger, especially the binary neutron star （BNS） merger, is critically important for gravitational wave （GW） astronomy, cosmology and fundamental physics. On Aug. 17, 2017, Advanced liGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart, GRB 170817A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope （he） onboard Insight-HXMT （Hard X-ray Modulation Telescope） is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart （SSS17a/AT2017gfo） with very large collection area （M000 cm2） and microsecond time resolution in 0.2-5 MeV. In addition, Insight-HXMT quickly implemented a Target of Opportunity （TOO） observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy （0.2-5 MeV） radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817A. Meanwhile, Insight-HXMT/he provides one of the most stringent constraints （-10-7 to 104 erg/cm2/s） for both GRB170817A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event.

关键词： GW170817 BNS merger gravitational wave electromagnetic counterpart

Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite

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Science China(Physics,Mechanics & Astronomy) 2020年第4期63卷 2-19页

作者： Shuang-Nan Zhang TiPei li FangJun Lu liMing Song YuPeng X u CongZhan liu Yong Chen xueLei Cao QingCui Bu Zhi Chang Gang Chen li Chen Tianxiang Chen YiBao Chen YuPeng Chen wei Cui weiwei Cui JingKang Deng Yongwei Dong Yuan Yuan Du Minxue Fu GuanHua Gao he Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor chengcheng Guo Dawei han wei Hu Yue Huang Jia Huo ShuMei Jia LuHua jiang weichun jiang Jing Jin YongJie Jin Bing li chengKui li Gang li MaoShun li wei li Xian li XiaoBo li XuFang li YanGuo li ZiJian li Zhengwei li XiaoHua liang JinYuan liao GuoQing liu hongwei liu ShaoZhen liu XiaoJing liu Yuan liu YiNong liu Bo Lu xueFeng Lu Tao Luo xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai Rencheng Shang Guohong Shen liang Sun Ying Tan lian Tao youli Tuo Chen wang chunQin wang GuoFeng wang HuanYu wang Juan wang WenShuai wang YuSa wang xiangYang Wen BaiYang wu BoBing wu Mei wu Guangcheng Xiao Shaolin Xiong linli Yan Jiawei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang chunLei Zhang chengMo Zhang Fan Zhang hongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang Ziliang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu Renlin Zhuang Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China

As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be *** we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results.

关键词： X-and γ-ray telescopes and instrumentation neutron stars black holes X-ray binaries γ-ray bursts

雪被斑块对川西高山森林凋落叶N和P释放的影响

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应用生态学报 2014年第8期25卷 2158-2166页

作者：何洁蒋先敏杨万勤倪祥银徐李亚李晗吴福忠四川农业大学生态林业研究所四川省林业生态工程省级重点实验室成都611130 四川省川西林业局四川理县623102

采用凋落物网袋法,研究冬季不同关键时期雪被斑块对川西高山森林6种代表性树种凋落物分解过程中N和P释放的影响.结果表明:整个雪被覆盖季节凋落物N表现为富集,P表现为释放,且雪被融化期P释放速率最大.厚型和中型雪被斑块下凋落物P释放... 详细信息

采用凋落物网袋法,研究冬季不同关键时期雪被斑块对川西高山森林6种代表性树种凋落物分解过程中N和P释放的影响.结果表明:整个雪被覆盖季节凋落物N表现为富集,P表现为释放,且雪被融化期P释放速率最大.厚型和中型雪被斑块下凋落物P释放速率大于薄型和无雪被斑块,而薄型和无雪被斑块下凋落物的N释放速率明显较高.6种凋落物N释放率和释放速率与日均温呈显著负相关;除岷江冷杉外,其他树种凋落物P释放率和释放速率与日均温表现为正相关.气候变暖情景下冬季雪被覆盖的减小将促进高山森林冬季凋落物分解过程中N释放,抑制P释放.

关键词：高山森林凋落物分解释放动态雪被斑块

Searching for ^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment

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Chinese Physics C 2024年第10期48卷 11-22页

作者： Bing-Tao Zhang Jun-Zheng wang li-Tao Yang Qian Yue Ke-Jun Kang Yuan-Jing li Hai-Peng An C.Greeshma Jian-Ping Chang Yun-Huan Chen Jian-Ping cheng Wen-han Dai Zhi Deng Chang-Hao Fang Xin-Ping Geng Hui Gong Qiu-Ju Guo Xu-Yuan Guo li he Sheng-Ming he Jin-wei Hu han-Xiong Huang Tu-Chen Huang Hai-Tao Jia Xi jiang S.Karmakar Hao-Bin li Jian-Min li Jin li Qian-Yun li Ren-Ming-Jie li xue-Qian li Yu-Lan li Yi-Fan liang Bin liao Fong-Kay lin Shin-Ted lin Jia-Xuan liu Shu-Kui liu Yan-Dong liu Yu liu Yuan-Yuan liu zhong-Zhi liu Hao Ma Yu-Cai Mao Qi-Yuan Nie Jin-Hua Ning Hui Pan Ning-chun Qi Jie Ren Xi-Chao Ruan Ze She Manoj Kumar Singh Tian-Xi Sun Chang-Jian Tang wei-you Tang Yang Tian Guang-Fu wang li wang Qing wang Yu-Feng wang Yun-xiang wang henry-Tsz-King Wong Shi-Yong wu Yu-cheng wu Hao-Yang Xing Rui Xu Yin Xu Tao xue Yu-Lu Yan Nan Yi chun-Xu Yu Hai-Jun Yu Jian-Feng Yue Ming Zeng Zhi Zeng Feng-Shou Zhang Lei Zhang Zhen-Hua Zhang Zhen-Yu Zhang Kang-Kang Zhao Ming-Gang Zhao Ji-Fang Zhou Zu-Ying Zhou Jing-Jun Zhou Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua UniversityBeijing 100084 Department of Physics Tsinghua UniversityBeijing 100084 Institute of Physics Academia SinicaTaipei 11529 NUCTECH Company Beijing 100084 YaLong River Hydropower Development Company Chengdu 610051 College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875 College of Physics Sichuan UniversityChengdu 610065 School of Physics Peking UniversityBeijing 100871 Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413 Sino-French Institute of Nuclear and Technology Sun Yat-sen UniversityZhuhai 519082 School of Physics Nankai UniversityTianjin 300071 Department of Physics Banaras Hindu UniversityVaranasi 221005 Department of Physics Beijing Normal UniversityBeijing 100875

We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China Jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of ^(76)Ge.A total of 504.3 kg⋅day effective exposure data was *** anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2089 keV for this work)with a factor of 23.A background level of 0.33 counts/(keV⋅kg⋅yr)was *** lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2)^(0ν)>1.0×10^(23)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:<3.2–7.5 eV.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge

Hunt-hess Ⅳ级颅内动脉瘤的早期血管内治疗

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中国介入影像与治疗学 2006年第1期3卷 26-28页

作者：刘爱华吴中学李佑祥姜除寒杨新健张静波北京市神经外科研究所北京100050

目的探讨早期血管内栓塞颅内Hunt-hess分级Ⅳ级动脉瘤的临床疗效及应用价值。方法回顾性分析早期血管内栓塞治疗颅内动脉瘤16例16个颅内动脉瘤。结果16例完全栓塞11例,大部分栓塞5例。1例死亡,并发动脉瘤破裂2例、脑血管痉挛3例、脑梗死... 详细信息

目的探讨早期血管内栓塞颅内Hunt-hess分级Ⅳ级动脉瘤的临床疗效及应用价值。方法回顾性分析早期血管内栓塞治疗颅内动脉瘤16例16个颅内动脉瘤。结果16例完全栓塞11例,大部分栓塞5例。1例死亡,并发动脉瘤破裂2例、脑血管痉挛3例、脑梗死2例、4例再次栓塞后痊愈。结论早期血管内栓塞是治疗颅内Hunt-hess分级Ⅳ级动脉瘤较理想方法。

关键词：颅内动脉瘤血管内治疗早期 Hunt-hess分级

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国产电解可脱弹簧圈的初步临床应用

中华神经外科杂志 2011年第7期27卷 656-659页

作者：姜鹏穆士卿张友平刘爱华吕明张静波姜除寒杨新健李佑祥吴中学首都医科大学附属北京天坛医院神经介入放射科、北京市神经外科研究所神经介入研究室 100050

目的初步总结了国产JASPER电解可脱弹簧圈的临床应用经验.方法采用117枚国产JASPER电解可脱弹簧圈栓塞颅内脑血管病共20例,其中颅内动脉瘤15例,硬脑膜动静脉瘘4例,外伤性颈动脉海绵窦瘘1例.20例中,单独应用JASPER电解可脱弹簧圈治疗9... 详细信息

目的初步总结了国产JASPER电解可脱弹簧圈的临床应用经验.方法采用117枚国产JASPER电解可脱弹簧圈栓塞颅内脑血管病共20例,其中颅内动脉瘤15例,硬脑膜动静脉瘘4例,外伤性颈动脉海绵窦瘘1例.20例中,单独应用JASPER电解可脱弹簧圈治疗9例,与其他品牌可脱弹簧圈联合使用者11例.结果国产JASPER电解可脱弹簧圈在顺滑程度、解旋情况、软硬程度、成篮效果、致密填塞情况与进口同类产品无明显差别,电解脱时间为（41.19±8.68）s,15例颅内动脉瘤完全栓塞10例,次全栓塞5例;4例硬脑膜动静脉瘘3例完全栓塞,部分栓塞1例;1例外伤性颈动脉海绵窦瘘完全栓塞.数字减影造影（DSA）复查7例无复发迹象.结论国产JASPER电解可脱弹簧圈性能可靠,临床效果确实.

关键词：可控电解弹簧圈栓塞颅内动脉瘤

基于CBERS-02B卫星CCD影像的东洞庭湖区洲滩钉螺孳生地探测

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中华流行病学杂志 2011年第6期32卷 583-586页

作者：李源培李林瀚何明祯赵飞何忠万卫李君祥姜杰周艺彪姜庆五复旦大学公共卫生学院流行病学教研室教育部公共卫生安全重点实验室上海200032 湖南省岳阳市君山区血防站

目的利用中巴地球资源卫星02B（CBERS-02B）卫星CCD影像，结合遥感（RS）与地理信息系统（GIS）相关技术，快速确定东洞庭湖区洲滩的可能钉螺孳生地。方法结合湖区洲滩钉螺适宜孳生地的两个典型特征：“冬陆夏水”的季节性淹水和“无草... 详细信息

目的利用中巴地球资源卫星02B（CBERS-02B）卫星CCD影像，结合遥感（RS）与地理信息系统（GIS）相关技术，快速确定东洞庭湖区洲滩的可能钉螺孳生地。方法结合湖区洲滩钉螺适宜孳生地的两个典型特征：“冬陆夏水”的季节性淹水和“无草不见螺”，利用遥感影像处理技术，分别计算出“冬陆夏水”区域和有植被覆盖区域，再将两区域叠加确定钉螺孳生地。最后与钉螺洲滩资料进行空间叠加对比验证。结果在东洞庭湖区，以水体差异指数（NDWI）〉0．01确定“冬陆夏水”区域，以植被指数（NDVI）〉0．36确定有植被覆盖区域，两区域叠加即为可能的钉螺孳生地区域。该区域与钉螺点空间资料的叠加对比验证显示符合率高达93．55％，提示预测结果良好。结论CBERS-02B卫星影像可以发现钉螺区域的分布特征和变化趋势，钉螺指数法（判别式1和2）适合用于湖沼地区洲滩钉螺孳生地的探测。

关键词：钉螺孳生地中巴地球资源卫星02B 湖沼地区植被指数水体差异指数

Genetic Architecture of Childhood Kidney and Urological Diseases in China

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Phenomics 2021年第3期1卷 91-104页

作者： Ye Fang Hua Shi Tianchao xiang Jiaojiao liu Jialu liu Xiaoshan Tang Xiaoyan Fang Jing Chen Yihui Zhai Qian Shen Guomin li li Sun Yunli Bi xiang wang Yanyan Qian Bingbing wu Huijun wang Wenhao Zhou Duan Ma Jianhua Mao Xiaoyun jiang Shuzhen Sun Ying Shen Xiaorong liu Aihua Zhang Xiaowen wang Wenyan Huang Qiu li Mo wang Xiaojie Gao Yubin wu Fang Deng Ruifeng Zhang Cuihua liu li Yu Jieqiu Zhuang Qing Sun Xiqiang Dang Haitao Bai Ying Zhu Siguang Lu Bili Zhang Xiaoshan Shao xuemei liu Mei han lijun Zhao Yuling liu Jian Gao Ying Bao Dongfeng Zhang Qingshan Ma liping Zhao Zhengkun Xia Biao Lu Yulong wang Mengzhun Zhao Jianjiang Zhang Shan Jian Guohua he Huifeng Zhang Bo Zhao Xiaohua li Feiyan wang Yufeng li hongtao Zhu Xinhui Luo Jinghai li Jia Rao hong Xu Department of Nephrology Children’s Hospital of Fudan UniversityNational Pediatric Medical Center of CHINA399 Wanyuan RoadShanghaiChina Shanghai Kidney Development and Pediatric Kidney Disease Research Center ShanghaiChina Shanghai Key Lab of Birth Defect Children’s Hospital of Fudan UniversityShanghai 201102China Department of Rheumatology Children’s Hospital of Fudan UniversityShanghaiChina Department of Urology Children’s Hospital of Fudan UniversityShanghaiChina Clinical Genetic Center Children’s Hospital of Fudan UniversityShanghaiChina Key Laboratory of Metabolism and Molecular Medicine Ministry of EducationDepartment of Biochemistry and Molecular BiologyInstitutes of Biomedical SciencesSchool of Basic Medical SciencesFudan UniversityShanghaiChina The Children Hospital of Zhejiang University School of Medicine HangzhouChina The First Affiliated Hospital of Sun Yat-Sen University GuangzhouChina Shandong Provincial Hospital JinanChina Bejing Children’s Hospital Affiliated to Capital University of Medical Science BeijingChina Children’s Hospital of Nanjing Medical University NanjingChina wuhan Children’s Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Shanghai Children’s Medical Centre Shanghai Jiaotong University School of MedicineShanghaiChina Children’s Hospital of Chongqing Medical University ChongqingChina Shenzhen Children’s Hospital ShenzhengChina Shengjing Hospital of China Medical University ShenyangLiaoningChina Anhui Provincial Children’s Hospital HefeiChina Xuzhou Children’s Hospital XuzhouChina henan Children’s Hospital ZhengzhouChina Guangzhou First People’s Hospital GuangzhouChina The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University WenzhouChina Qingdao Women and Children’s Hospital QingdaoChina xiangya Hospital Central South University ChangshaHunanChina The First Affiliated Hospital of Xiamen University XiamenChina First Affiliated Hospital of Anhui Medical University HefeiC

Kidney disease is manifested in a wide variety of phenotypes,many of which have an important hereditary *** delineate the genotypic and phenotypic spectrum of pediatric nephropathy,a multicenter registration system is being imple-mented based on the Chinese Children Genetic Kidney Disease Database(CCGKDD).In this study,all the patients with kidney and urological diseases were recruited from 2014 to *** analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal *** genetic diagnosis was confirmed in 883 of 2256(39.1%)patients from 23 provinces in *** profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome(SRNS,23.5%),glomerulonephritis(GN,32.2%),congenital anomalies of the kidney and urinary tract(CAKUT,21.2%),cystic renal disease(3.9%),renal calcinosis/stone(3.6%),tubulopathy(9.7%),and chronic kidney disease of unknown etiology(CKDu,5.8%).The pathogenic variants of 105 monogenetic disorders were *** distinct genomic disorders were identified as pathogenic copy number variants(CNVs)in 11 *** diagnostic yield differed by subgroups,and was highest in those with cystic renal disease(66.3%),followed by tubulopathy(58.4%),GN(57.7%),CKDu(43.5%),SRNS(29.2%),renal calcinosis/stone(29.3%)and CAKUT(8.6%).Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic *** present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was *** data demonstrate the utility of family-based exome sequencing,and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

关键词： Chronic kidney disease(CKD) Exome sequencing(ES) Steroid-resistant nephrotic syndrome(SRNS) Congenital anomalies of the kidney and urinary tract(CAKUT) Nephronophthisis(NPHP) Polycystic kidney disease(PKD)