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Elite,transformable haploid inducers in maize

The Crop Journal 2024年第1期12卷 314-319页

作者： Brent Delzer Dawei Liang David Szwerdszarf Isadora Rodriguez Gonzalo Mardones Sivamani Elumalai Francine Johnson Samson Nalapalli Rachel Egger Erin Burch Kerry Meier Juan Wei Xiujuan Zhang Huaping Gui Huaibing Jin Huan Guo Kun Yu yubo Liu Becky Breitinger Ana Poets Jason Nichols Wan Shi David Skibbe Qiudeng Que Timothy Kelliher Seeds Development Syngenta SeedsJanesvilleWI 53546USA Seeds Research Syngenta Biotechnology China Co.Ltd.Beijing 102206China Centro de Investigación de Cultivos Arica Syngenta R&DArica 1000000Chile Syngenta S.A. Proyecto la SoledadGraneros 2880000Chile Seeds Research Syngenta Crop Protection LLCRTPNC 27709USA Seeds Development Syngenta SeedsSlaterIA 50244USA

The introduction of alleles into commercial crop breeding pipelines is both time consuming and *** technologies that are disrupting traditional breeding processes are doubled haploid(DH)breeding and genome editing(GE).Recently,these techniques were combined into a GE trait delivery system called HI-Edit(Haploid Inducer-Edit).In HI-Edit,the pollen of a haploid inducer line is reprogrammed to deliver GE traits to any variety,obviating recurrent *** HI-Edit to operate at scale,an efficient transformable HI line is needed,but most maize varieties are recalcitrant to transformation,and haploid inducers are especially difficult to transform given their aberrant reproductive *** marker assisted selection and a three-tiered testing scheme,we report the development of new Iodent and Stiff Stalk maize germplasm that are transformable,have high haploid induction rates,and exhibit a robust,genetically-dominant anthocyanin native trait that may be used for rapid haploid *** show that transformation of these elite‘‘HI-Edit”lines is enhanced using the BABYBOOM and WUSCheL morphogenetic ***,we evaluate the HI-Edit performance of one of the lines against both Stiff Stalk and non-Stiff Stalk *** strategy and results of this study should facilitate the development of commercially scalable HI-Edit systems in diverse crops.

关键词： Zea mays L Doubled haploids Transformation Genome editing QTL

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Polar-coordinate line-projection light-curing continuous 3D printing for tubular structures

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International Journal of Extreme Manufacturing 2024年第04期 251-265页

作者： Huiyuan Wang Siqin Liu Xincheng Yin Mingming Huang Yanzhe Fu Xun Chen Chao Wang Jingyong Sun Xin Yan Jianmin Han Jiping Yang Zhijian Wang Lizhen Wang yubo Fan Jiebo Li Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of EducationInstitute of Medical PhotonicsBeijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang University School of Mechanical Engineering and Automation Beihang University Peking University School and Hospital of Stomatology School of Materials Science and Engineering Beihang University

3D printing techniques offer an effective method in fabricating complex radially multi-material structures. However, it is challenging for complex and delicate radially multi-material model geometries without supporting structures, such as tissue vessels and tubular graft, among *** this work, we tackle these challenges by developing a polar digital light processing technique which uses a rod as the printing platform. The 3D model fabrication is accomplished through line projection. The rotation and translation of the rod are synchronized to project and illuminate the photosensitive material volume. By controlling the distance between the rod and the printing window, we achieved the printing of tubular structures with a minimum wall thickness as thin as50 micrometers. By controlling the width of fine slits at the printing window, we achieved the printing of structures with a minimum feature size of 10 micrometers. Our process accomplished the fabrication of thin-walled tubular graft structure with a thickness of only 100micrometers and lengths of several centimeters within a timeframe of just 100 s. Additionally, it enables the printing of axial multi-material structures, thereby achieving adjustable mechanical strength. This method is conducive to rapid customization of tubular grafts and the manufacturing of tubular components in fields such as dentistry, aerospace, and more.

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Non-specific Lipid Transfer Protein StLTP6Promotes Virus Infection by Inhibiting Jasmonic Acid Signaling Pathway in Response to PVS TGB1

Non-specific Lipid Transfer Protein StLTP6Promotes Virus Inf...

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中国植物病理学会2024年学术年会

作者： SHANG Kaijie WANG Chenchen WANG Xipan XU Kaihao WANG yubo ZHOU Shumei LIU Hongmei ZHU Xiaoping ZHU Changxiang

Plant viruses use host factors for successful ***-specificlipid transfer proteins(nsLTPs) are important in plant-pathogen interactionshowever,their roles and underlying molecular mechanisms in viral infections remain largely *** virus S(PVS) is one of the most serious viruses on *** present,there is no report on the mechanism of interaction between PVS-encoded protein and host factors,and little is known about which host factors are involved in regulating the virus *** acid(JA),as a plant hormone,is an important regulatory factor in the process of plant resistance to virus ***,we screened and verified that our previously reported pro-viral factor,StLTP6,could interact with the PVS-silencing suppressor triple gene block 1(TGB1) *** PVS TGB1 protein can induce the expression of StLTP6 and alter its original localization through ***,StLTP6 interacts with allene oxide cyclase and inhibits its accumulation,suppressing jasmonic acid ***,the inhibition of JA synthesis reduces its induction of host RNA silencing antiviral defense response,there by allowing virus *** summary,the molecular mechanism by which PVS TGB1 interacts with StLTP6 to promote PVS infection was *** findings broaden our understanding of the biological function of nsLTP and provides a new antiviral target for potato research.

关键词： non-specific lipid transfer protein potato virus S triple gene block 1 protein signaling pathway jasmonic acid

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基于多光子纠缠的具有身份认证功能的多方量子安全直接通信

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科学通报 2024年第11期69卷 1491-1500页

作者：刘成杜明明钟伟盛宇波周澜南京邮电大学理学院南京210023 南京邮电大学电子与光学工程学院柔性电子(未来技术)学院南京210023 南京邮电大学量子信息与技术研究所南京210003

多方量子安全直接通信(multi-party quantum secure direct communication,MQSDC)可使多个信息发送方通过量子信道同时向一个信息接收方传递秘密信息,并从理论上保证传递信息的绝对安全性.已有的MQSDC方案均默认所有通信方为合法通信方... 详细信息

多方量子安全直接通信(multi-party quantum secure direct communication,MQSDC)可使多个信息发送方通过量子信道同时向一个信息接收方传递秘密信息,并从理论上保证传递信息的绝对安全性.已有的MQSDC方案均默认所有通信方为合法通信方,这在实际实验条件下难以保证,为窃听者冒充合法通信方窃取信息或扰乱通信提供了可能.本文提出了基于Greenberger-Horne-Zeilinger(GHZ)态的具有身份认证功能的三方量子安全直接通信方案.信息接收方可同时认证两个实际信息发送方的身份,确认身份合法后,再接收其发送的秘密信息,理论上可保证合法通信方身份认证码以及传输信息的安全.本方案使用单光子测量代替GHZ态测量,操作简单且成功率高.本文对方案在实际实验条件下的安全信息容量进行了数值模拟.本方案在未来量子网络领域具有重要的应用.

关键词：多方量子安全直接通信身份认证 Greenberger-Horne-Zeilinger态安全信息容量

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Physical-barrier detection based collective motion analysis

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Frontiers of Computer Science 2019年第2期13卷 426-436页

作者： Gaoqi he Qi CheN Dongxu JIANG yubo YUAN Xingjian LU Department of Computer Science and Engineering East China University of Science and Technology Shanghai 200237 China State Key Laboratory of Virtual Reality Technology and Systems Beihang University Beijing 100191 China Smart City Collaborative Innovation Center Shanghai Jiao Tong University Shanghai 200240 China

Collective motion is one of the most fascinating phenomena and mainly caused by the interactions between individuals. Physical-barriers, as the particular facilities which divide the crowd into different lanes, greatly affect the measurement of such interactions. In this paper we propose the physical-barrier detection based collective motion analysis (PDCMA) approach. The main idea is that the interaction between spatially adjacent pedestrians actually does not exist if they are separated by the physical-barrier. Firstly, the physical-barriers are extracted by two-stage clustering. The scene is automatically divided into several motion regions. Secondly, local region collectiveness is calculated to represent the interactions between pedestrians in each region. Finally, extensive evaluations use the three typical methods, i.e., the PDCMA, the Collectiveness, and the average normalized Velocity, to show the efficiency and efficacy of our approach in the scenes with and without physical barriers. Moreover, several escalator scenes are selected as the typical physical-barrier test scenes to demonstrate the performance of our approach. Compared with the current collective motion analysis methods, our approach better adapts to the scenes with physical barriers.

关键词： crowd behavior analysis collective motion physical-barrier detection two-stage clustering local region collectiveness

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线粒体的力学生物学研究进展

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医用生物力学 2024年第3期39卷 545-551页

作者：纳静郑丽沙樊瑜波北京航空航天大学生物与医学工程学院生物力学与力生物学教育部重点实验室北京市生物医学工程高精尖创新中心北京100083

线粒体是高度动态的细胞器,不仅为细胞提供能量和物质基础,同时参与调控细胞的增殖、迁移、分化和凋亡等。细胞命运受来自微环境的力学信号调节。近年来的研究表明,力学因素对细胞的能量代谢具有调控作用。线粒体作为一个力学感受器和枢... 详细信息

线粒体是高度动态的细胞器,不仅为细胞提供能量和物质基础,同时参与调控细胞的增殖、迁移、分化和凋亡等。细胞命运受来自微环境的力学信号调节。近年来的研究表明,力学因素对细胞的能量代谢具有调控作用。线粒体作为一个力学感受器和枢纽,连接力学和代谢来调控细胞的命运。深入理解力学微环境和线粒体代谢的关系,为促进组织再生和疾病治疗提供有力的指导。本文主要介绍线粒体力学生物学研究进展,并探讨其在组织再生和疾病治疗中的潜在应用。

关键词：线粒体力学微环境力学转导组织再生癌症

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数字金融发展对传统银行信贷业务的影响——来自2011—2019年地级市面板数据的证据

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新金融 2024年第1期 51-58页

作者：夏兵玉詹宇波上海社会科学院经济研究所

数字金融的发展对传统银行信贷业务产生了不确定性影响,厘清数字金融和传统银行信贷业务的辩证关系,探寻两者协调发展之路具有重要现实意义。本文利用银行局部均衡模型分析数字金融通过存贷款利差和降低银行管理成本两方面对传统银行信... 详细信息

数字金融的发展对传统银行信贷业务产生了不确定性影响,厘清数字金融和传统银行信贷业务的辩证关系,探寻两者协调发展之路具有重要现实意义。本文利用银行局部均衡模型分析数字金融通过存贷款利差和降低银行管理成本两方面对传统银行信贷业务的异质影响,借助2011—2019年国内地级市经济数据和数字金融指数实证,研究发现,在发展初期,数字金融正向促进了传统银行信贷业务发展,但数字金融发展到一定阶段后会负向影响传统银行信贷业务;进一步探究数字金融分指数的影响,覆盖广度分指数对传统银行信贷业务在初期表现为抑制作用,中长期为促进作用;使用深度分指数对传统银行信贷业务主要表现为促进效应;而数字化程度分指数实证影响不显著。此外,研究发现相对于中西部地区,东部发达地区数字金融指数对传统银行信贷业务能在更大的范围内发挥促进作用。

关键词：数字金融发展传统银行信贷业务 “倒U型”关系数字金融指数

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中国人的思维方式与心理健康:心理弹性与自尊的作用

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心理科学 2024年第2期47卷 458-466页

作者：黄莲琼罗曦侯玉波北京大学心理与认知科学学院暨行为与心理健康北京市重点实验室北京100871

本研究探究了中国人思维方式与心理健康的关系以及心理弹性和自尊在其中的作用。对630份有效数据进行分析后发现,思维的联系性正向预测心理健康,矛盾性则负向预测心理健康;心理弹性在思维方式与心理健康间起中介作用;自尊不仅调节思维... 详细信息

本研究探究了中国人思维方式与心理健康的关系以及心理弹性和自尊在其中的作用。对630份有效数据进行分析后发现,思维的联系性正向预测心理健康,矛盾性则负向预测心理健康;心理弹性在思维方式与心理健康间起中介作用;自尊不仅调节思维方式与心理健康的关系,也调节思维方式与心理弹性以及心理弹性与心理健康的关系,在该研究模型中起核心作用。这些结果不仅揭示了思维方式影响心理健康的机制,而且特别强调自尊在此过程中的重要作用。

关键词：思维方式心理健康心理弹性自尊

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Inhibitory effect and mechanism of tannic acid against two starch digestive enzymes

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Food Quality and Safety 2024年第1期8卷 115-123页

作者：钟毓秀倪德让杨玉波李元一王莉田金虎杨帆叶兴乾 Department of Food Science and Nutrition Zhejiang Key Laboratory for Agri-Food ProcessingFuli Institute of Food ScienceZhejiang R&D Centre for Food Technology and EquipmentZhejiang UniversityHangzhouChina Institute of Science and Technology Moutai GroupZunyiChina Key Laboratory of Industrial Microbial Resources Development Kweichow Moutai Co.Ltd.RenhuaiChina

Backgrounds:Tannic acid(TA),as a plant-derived phenolic substance,is involved in regulating the activity of starch digestive enzymes,but its underlying mechanism remains *** and Results:In the present study,inhibition rate and inhibition kinetics assays were performed and confrmed that TA had a strong inhibitory effect on bothα-amylase andα-glucosidase with IC50 values of 0.1585 mg/mL and 0.00542 mg/mL,respectively,through a mixed inhibition *** secondary structures of both enzymes were confrmed to be modifed by TA through circular dichroism(CD)*** quenching analysis revealed that the interaction between TA and two enzymes was a static process of pontaneous complex ***,molecular docking revealed that non-covalent bonds were the main interaction forces between TA and both ***:Thus,TA was a promising candidate for the inhibition of starch-digesting enzymes,and the present research provided insight into postprandial glucose regulation through polyphenols.

关键词： Tannic acid α-amylase α-glucosidase inhibition starch digestion.

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水牛奶营养物质及其制品研究现状

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食品工业科技 2024年第18期45卷 344-354页

作者：裴昱博于淼张国芳李春东北农业大学食品学院黑龙江哈尔滨150030 东北农业大学黑龙江省绿色食品科学研究院黑龙江哈尔滨150028

水牛奶中干物质含量较高,其综合营养价值高于普通牛奶,是多种生物活性成分的良好来源。因此,水牛奶及其相关制品受到越来越多的消费者的关注。本文根据水牛奶营养物质及其制品相关研究的前沿成果,介绍了水牛奶中蛋白质、脂肪、碳水化合... 详细信息

水牛奶中干物质含量较高,其综合营养价值高于普通牛奶,是多种生物活性成分的良好来源。因此,水牛奶及其相关制品受到越来越多的消费者的关注。本文根据水牛奶营养物质及其制品相关研究的前沿成果,介绍了水牛奶中蛋白质、脂肪、碳水化合物及其他营养物质的含量及其理化性质,同时针对水牛奶乳制品,如干酪、奶油、酸奶、冰淇淋等制备和相关研究进行了概述,最后针对水牛奶中的生物活性物质开发功能性食品的可能性提供了见解,为企业研发水牛奶相关产品提供参考。

关键词：水牛奶营养物质酪蛋白乳脂肪水牛奶制品

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