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Prediction of Lubricant Physicochemical Properties Based on Gaussian Copula Data Expansion

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China Petroleum Processing & Petrochemical Technology 2024年第1期26卷 161-174页

作者： Feng Xin Yang rui Xie Peiyuan xia Yanqiu School of Energy Power and Mechanical Engineering North China Electric Power UniversityBeijing 102206China

The composition of base oils affects the performance of lubricants made from *** paper proposes a hybrid model based on gradient-boosted decision tree(GBDT)to analyze the effect of different ratios of KN4010,PAO40,and PriEco3000 component in a composite base oil system on the performance of *** study was conducted under small laboratory sample conditions,and a data expansion method using the Gaussian Copula function was proposed to improve the prediction ability of the hybrid *** study also compared four optimization algorithms,sticky mushroom algorithm(SMA),genetic algorithm(GA),whale optimization algorithm(WOA),and seagull optimization algorithm(SOA),to predict the kinematic viscosity at 40℃,kinematic viscosity at 100℃,viscosity index,and oxidation induction time performance of the *** results showed that the Gaussian Copula function data expansion method improved the prediction ability of the hybrid model in the case of small *** SOA-GBDT hybrid model had the fastest convergence speed for the samples and the best prediction effect,with determination coefficients(R^(2))for the four indicators of lubricants reaching 0.98,0.99,0.96 and 0.96,***,this model can significantly reduce the model’s prediction error and has good prediction ability.

关键词： base oil data augmentation machine learning performance prediction seagull algorithm

P-aminobenzoic acid promotes retinal regeneration through activation of Ascl1a in zebrafish

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Neural Regeneration Research 2024年第8期19卷 1849-1856页

作者： Meihui he Mingfang xia Qian Yang Xingyi Chen Haibo Li xiaobo xia Eye Center of xiangya Hospital Central South UniversityChangshaHunan ProvinceChina Hunan Key Laboratory of Ophthalmology ChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

The retina of zebrafish can regenerate completely after injury.M ultiple studies have demonstrated that metabolic alte rations occur during retinal damage;however to date no study has identified a link between metabolites and retinal regeneration of ***,we performed an unbiased metabolome sequencing in the N-methyl-D-aspartic acid-damaged retinas of zebrafish to demonstrate the metabolomic mechanism of retinal *** the differentially-ex pressed metabolites,we found a significant decrease in p-aminobenzoic acid in the N-methyl-D-aspartic acid-damaged retinas of ***,we investigated the role of p-aminobenzoic acid in retinal regeneration in adult *** rtantly,p-aminobenzoic acid activated Achaetescute complex-like 1a expression,thereby promoting Müller glia reprogramming and division,as well as Müller glia-derived progenitor cell ***,we eliminated folic acid and inflammation as downstream effectors of PABA and demonstrated that PABA had little effect on Müller glia *** together,these findings show that PABA contributes to retinal regeneration through activation of Achaetescute complex-like 1a expression in the N-methyl-Daspartic acid-damaged retinas of zebrafish.

关键词： Achaetescute complex-like 1a(Ascl1a) metabolomics Müller glia p-aminobenzoic acid(PABA) retina regeneration zebrafish

Knowledge and data jointly driven aeroengine gas path performance assessment method

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Chinese Journal of Aeronautics 2024年第5期37卷 533-557页

作者： Zhe WANG Xuyun FU rui ZHANG Zhengfeng BAI xiangzhao xia Wei JIANG Department of Mechanical Engineering Harbin Institute of TechnologyWeihai 264209China Weihai Key Laboratory of Intelligent Operation and Maintenance Harbin Institute of TechnologyWeihai 264209China Control System Design Laboratory AECC ShenYang Engine Research InstituteShenyang 110015China

Aeroengines,as the sole power source for aircraft,play a vital role in ensuring flight *** gas path,which represents the fundamental pathway for airflow within an aeroengine,directly impacts the aeroengine's performance,fuel efficiency,and ***,timely and accurate evaluation of gas path performance is of paramount *** paper proposes a knowledge and data jointly driven aeroengine gas path performance assessment method,combining Fingerprint and gas path parameter deviation ***,Fingerprint is used to correct gas path parameter deviation values,eliminating parameter shifts caused by non-component performance ***,coarse errors are removed using the Romanovsky criterion for short-term data divided by an equal-length overlapping sliding ***,an Ensemble Empirical Mode Decomposition and Non-Local Means(EEMD-NLM)filtering method is designed to“clean”data noise,completing the preprocessing for gas path parameter deviation ***,based on the characteristics of gas path parameter deviation values,a Dynamic Temporary Blended Network(DTBN)model is built to extract its temporal features,cascaded with Multi-Layer Perceptron(MLP),and combined with Fingerprint to construct a Dynamic Temporary Blended AutoEncoder(DTB-AutoEncoder).Eventually,by training this improved autoencoder,the aeroengine gas path multi-component performance assessment model is formed,which can sufficiently decouple the nonlinear mapping relationship between aeroengine gas path multi-component performance degradation and gas path parameter deviation values,thereby achieving the performance assessment of engine gas path *** practical application cases,the effectiveness of this model in assessing the aeroengine gas path multi-component performance is verified.

关键词： Performance assessment Aeroengine Fingerprint Gas path parameter deviation values Jointly drive

Hierarchical Controller Synthesis Under Linear Temporal Logic Specifications Using Dynamic Quantization

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IEEE/CAA Journal of Automatica Sinica 2024年第10期11卷 2082-2098页

作者： Wei Ren Zhuo-rui Pan Weiguo xia Xi-Ming Sun the Key Laboratory of Intelligent Control and Optimization for Industrial Equipment of Ministry of Education Dalian University of Technology the School of Control Science and Engineering Dalian University of TechnologyDalian 116024China

Linear temporal logic(LTL)is an intuitive and expressive language to specify complex control tasks,and how to design an efficient control strategy for LTL specification is still a *** this paper,we implement the dynamic quantization technique to propose a novel hierarchical control strategy for nonlinear control systems under LTL *** on the regions of interest involved in the LTL formula,an accepting path is derived first to provide a high-level solution for the controller synthesis ***,we develop a dynamic quantization based approach to verify the realization of the accepting *** realization verification results in the necessity of the controller design and a sequence of quantization regions for the controller ***,the techniques of dynamic quantization and abstraction-based control are combined together to establish the local-to-global control *** abstraction construction and controller design are local and dynamic,thereby resulting in the potential reduction of the computational *** each quantization region can be considered locally and individually,the proposed hierarchical mechanism is more efficient and can solve much larger problems than many existing ***,the proposed control strategy is illustrated via two examples from the path planning and tracking problems of mobile robots.

关键词： Abstraction-based control design dynamic quantization formal methods linear temporal logic(LTL)

Light/pH dual-responsive magnetic metal-organic frameworks composites for phosphorylated peptide enrichment

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Chinese Chemical Letters 2024年第7期35卷 222-226页

作者： rui Wang he Qi Haijiao Zheng Qiong Jia College of Chemistry Jilin UniversityChangchun 130012China Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education School of Life SciencesJilin UniversityChangchun 130012China

Metal-organic frameworks(MOFs)combined with specific ligands are highly adaptable smart materials that can respond to external and physiological *** this study,we introduced a pyridinyl zwitterionic ligand with light/pH dual response into magnetic MOF composite(Fe_(3)O_(4)@ZW-MOF)for enrichment of phosphorylated peptides for the first *** introduction of the developed ligand gives MOF material dual response *** stimulation affects the generation/disappearance of free radicals of the pyridine derivative,resulting in a change in the charge gradient of the zwitterion,and zwitterion can also regulate the p H of the solution by adding acid or ***,the reversible capture and release of phosphorylated peptides can be easily achieved by adjusting light and *** established phosphorylated peptide enrichment platform exhibits high sensitivity(detection limit of 1 fmol),high selectivity(β-casein:BSA,1:1000),and good reusability(7 cycles).In addition,the method was applied to the enrichment of phosphorylated peptides in complex systems(non-fat milk and human serum),demonstrating the feasibility of this method for phosphoproteom *** conclusion,the synthesized Fe_(3)O_(4)@ZW-MOF is a promising MOF material,which provides the possibility to advance the application of responsive MOFs materials in proteomics.

关键词： Light pH Dual-response Metal-organic frameworks Phosphorylated peptide

Learning group interaction for sports video understanding from a perspective of athlete

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Frontiers of Computer Science 2024年第4期18卷 175-188页

作者： rui he Zehua FU Qingjie LIU Yunhong WANG Xunxun CheN Intelligent Recognition and Image Processing(IRIP)Lab School of Computer Science and EngineeringBeihang UniversityBeijing 100191China Hangzhou Innovation Institute Behang UniversityHangzhou 310051China National Computer Network Emergency Response Technical Team/Coordination Center of China(CNCERT or CNCERT/CC) Beijing 100029China

Learning activities interactions between small groups is a key step in understanding team sports *** research focusing on team sports videos can be strictly regarded from the perspective of the audience rather than the *** team sports videos such as volleyball and basketball videos,there are plenty of intra-team and inter-team *** this paper,a new task named Group Scene Graph Generation is introduced to better understand intra-team relations and inter-team relations in sports *** tackle this problem,a novel Hierarchical Relation Network is *** all players in a video are finely divided into two teams,the feature of the two teams’activities and interactions will be enhanced by Graph Convolutional Networks,which are finally recognized to generate Group Scene *** evaluation,built on Volleyball dataset with additional 9660 team activity labels,a Volleyball+dataset is proposed.A baseline is set for better comparison and our experimental results demonstrate the effectiveness of our ***,the idea of our method can be directly utilized in another video-based task,Group Activity *** show the priority of our method and display the link between the two ***,from the athlete’s view,we elaborately present an interpretation that shows how to utilize Group Scene Graph to analyze teams’activities and provide professional gaming suggestions.

关键词： group scene graph group activity recognition scene graph generation graph convolutional network sports video understanding

Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea

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Frontiers of Environmental Science & Engineering 2024年第9期18卷 27-38页

作者： Jian Lu Jun Wu Cui Zhang Jianhua Wang xia he CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation Yantai Institute of Coastal Zone Research(YIC)Chinese Academy of Sciences(CAS)Shandong Key Laboratory of Coastal Environmental ProcessesYICCASYantai 264003China Yantai Research Institute Harbin Engineering UniversityYantai 264006China College of Environmental Science and Engineering Guilin University of TechnologyGuilin 541006China

Antibiotic resistance genes(ARGs)might have great effect on ecological security and human *** are important reservoirs that receive tremendous amounts of pollutants ***,information on the proliferation of ARGs in seawater is still *** study performed field sampling to investigate the occurrence and distribution of ARGs in seawater of the South China Sea,which is the deepest and largest sea in *** results showed that the total absolute abundances of ARGs in seawater samples ranged from 2.1×10^(3)to 2.3×10^(4)copies/mL,with an of 5.0×10^(3)copies/mL and a range of 2.2×10^(3)–1.8×10^(4)copies/mL for those with mobile genetic elements(MGEs).Genes resistant to multidrug,aminoglycoside,tetracycline,and fluoroquinolone antibiotics accounted for 77.3%–88.6%of total ARGs in *** and Cyanobacteria represented 32.1%–56.2%and 30.4%–49.5%of microbial community,***_MIT9313 and Clade_la were the prevalent genera in seawater of the South China *** co-occurrence relationship existed among ARGs,MGEs,and *** activities had critical influence on ARGs and *** wastewater,wastewater treatment plant effluent,sewage,aquaculture tailwater,and runoff were determined as the important sources of ARGs in seawater of the South China Sea based on positive matrix factorization analysis.

关键词： The South China Sea Antibiotic resistance genes Mobile genetic element Source apportionment

Self-assembled amphiphilic NIR-Ⅱ emissive nano-micelles for imaging-guided photothermal therapy of colorectal cancer

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Science China Chemistry 2024年第8期67卷 2767-2774页

作者： Axin he Fangfang xia Da Han Qinglai Yang Weihong Tan Institute of Molecular Medicine(IMM) Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200240China Center for Molecular Imaging Probe Hunan Province Key Laboratory of Cancer Cellular and Molecular PathologyCancer Research InstituteHengyang Medical SchoolUniversity of South ChinaHengyang 421001China The Key Laboratory of Zhejiang Province for Aptamers and Theranostics Zhejiang Cancer Hospital Hangzhou Institute of Medicine(HIM)Chinese Academy of SciencesHangzhou 310022China Molecular Science and Biomedicine Laboratory(MBL) State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical EngineeringCollege of BiologyAptamer Engineering Center of Hunan ProvinceHunan UniversityChangsha 410082China

Colorectal cancer(CRC) is one of the major causes of cancer-related mortality worldwide. Most near-infrared(NIR) agents used in clinical CRC treatment are at NIR-I(700–900 nm) window, which has limitations on deep tissue, and fluorescent probes in the second NIR(1,000–1,700 nm) allow high-resolution bioimaging with deep tissue penetration. However, existing NIR-II fluorophores used in clinical are still rare. herein, based on shielding-donor-acceptor-donor-shielding(S-D-A-D-S) scaffold, we developed an organic small-molecule fluorophore IR-BTGP with NIR-II emission for imaging-guided photothermal therapy(PTT) in CRC mice model. Amphiphilic IR-BTGP can be self-assembled into spherical nano-micelles, which presents reliable water solubility and photothermal conversion efficiency(30.2%). In vitro experiments indicate that cancer cells treated with IRBTGP were significantly killed upon 808 nm light irradiation. Furthermore, in vivo NIR-II fluorescence imaging confirms that IR-BTGP accumulates in the tumor region. Remarkably, a significant tumor inhibition rate(78.5%) was observed in tumorbearing mice when treated with IR-BTGP plus 808 nm irradiation. Therefore, this work shows that IR-BTGP holds great promise as an NIR-II fluorescence imaging-guided PTT platform for CRC in the future.

关键词： photothermal therapy(PTT) second near-infrared(NIR-Ⅱ)imaging organic molecule

Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population

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Chinese Medical Journal 2018年第12期131卷 1430-1435页

作者： Yan-Jie Liu xiao-Zeng Wang Ya Wang rui-xia he Lin Yang Quan-Min Jing Hai-Wei Liu Department of Cardiology Institute of Cardiovascular Research General Hospital of Shenyang Military Region Shenyang Liaoning 110016 China

Background： The prevalence, presentation, management, and prognosis of coronary heart disease differ according to sex. Greater understanding on the differences between men and women with acute aortic dissection （AAD） is needed. We aimed to investigate whether sex disparities are found in patients with AAD, and to study sex differences in complications, mortality in-hospital, and tong-term. Methods： We included 884 patients enrolled in our institute between June 2002 and May 2016. Considering psychosocial factors, treatments, and the outcomes in men versus those in women with AAD, we explored the association of sex with psychosocial characteristics and mortality risk. For categorical variables, significant differences between groups were assessed with the Chi-square test or Fisher＇s exact test, and continuous parameters were assessed with Student＇s t-test. Univariate and stratified survival statistics were computed using Kaplan-Meier analysis. Results： A total of 884 patients （76.1% male, mean age 51.4 ± 11.8 years） were inchidcd in this study. There were fewer current smokers in female compared with male （ 17.5% vs. 67.2%,χ^2= 160.06, P〈 0.05）. The percentage of men who reported regular alcohol consumption was significantly higher than that in women （40.6% vs. 3.8%, χ^2== 100.18, P 〈 0.05）. About 6.2% （55 of 884） of patients with AAD died before vascular or endovascular surgery was performed, 34.4% （304 of 884） of patients underwent surgical procedures, and 52.7% （466 of 884） and 12.8% （113 of 884） of patients received endovascular treatment and medication, Postoperative mortality similar （6.0% vs. 5.6%, respectively, χ^2= 0.03, P = 0.91） between men and women. Follow-up was completed in 653 of 829 patients （78.8%）. Adjustment for age, history of coronary disease, hypertension, smoking and drinking, Type A and use of beta-blocker, angiotensin II receptor blockers, angiotensin converting enzyme （ACE） inhibitor, calcium-channel blockers and statins by multivariate log

关键词： Aortic Dissection: Prognosis Sex