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Congenital bronchoesophageal fistula in adults

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World Journal of Gastroenterology 2011年第10期17卷 1358-1361页

作者： bao-Shi Zhang nai-Kang Zhou Chang-Hai Yu Department of Cardio-tho-raeic Surgery First Affiliated Hospital of Chinese PLA General Hospital Beijing 100048 China Department of Thoracic Surgery Chinese PLA General Hospital Beijing 100853 China

AIM: To study the clinical characteristics, diagnosis and surgical treatment of congenital bronchoesophageal fi stulae in adults. METHODS: Eleven adult cases of congenital bronchoesophageal fistula diagnosed and treated in our hospital between May 1990 and August 2010 were reviewed. Its clinical presentations, diagnostic methods, anatomic type, treatment, and follow-up were recorded. RESULTS: Of the chief clinical presentations, nonspecific cough and sputum were found in 10 (90.9%), recurrent bouts of cough after drinking liquid food in 6 (54.6%), hemoptysis in 6 (54.6%), low fever in 4 (36.4%), and chest pain in 3 (27.3%) of the 11 cases, respectively. The duration of symptoms before diagnosis ranged 5-36.5 years. The diagnosis of congenital bronchoesophageal fistulae was established in 9 patients by barium esophagography, in 1 patient by esophagoscopy and in 1 patient by bronchoscopy, respectively. The congenital bronchoesophageal fistulae communicated with a segmental bronchus, a main bronchus, and an intermediate bronchus in 8, 2 and 1 patients, *** treatment of congenital bronchoesophageal fistulae involved excision of the fistula in 10 patients or division and suturing in 1 patient. The associated lung lesion was removed in all patients. No long-term sequelae were found during the postoperative follow-up except in 1 patient with bronchial fistula who accepted reoperation before recovery. CONCLUSION: Congenital bronchoesophageal fistula is rare in adults. Its most useful diagnostic method is esophagography. It must be treated surgically as soon as the diagnosis is established.

关键词： Congenital bronchoesophageal fistula Adult Esophagography Surgical treatment

Effect of topotecan on retinocytoma cell apoptosis and expression of Livin and PTEN

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Chinese Medical Journal 2013年第2期126卷 340-344页

作者： ZHANG Meng SHAN bao-en YUAN nai-fen LIU Wei hebeiMedical University Fourth Hospital Department of Ophthalmology Hebei 05001 lChina hebeiMedical University Fourth Hospital ResearchCenter Hebei 05001 lChina hebeiMedical'University Fourth Hospital Department of Oncology Hebei 050011China

Background Retinocytoma （RB） is a very common intraocular malignant tumor during infancy. Chemotherapy has gradually been used as the first-line treatment for intraocular RB in recent years. In this study, Livin and PTEN expressions were observed in the RB tissue, along with the growth-inhibiting and apoptosis-induced effects of topotecan （TPT） on RB HXO-Rb44 cell strain. This study aimed to investigate the antigrowth effects of TPT on RB cell strain HXO-Rb44. Methods Max-VisionTM rapid immunohistochemistry was adopted to detect Livin and PTEN expressions in the normal retina and in RB, and their relationship with RB clinicopathologic features was analyzed. Human RB cell strain HXO-Rb44 was cultivated and passaged. MTT method was used to measure the survival rates of HXO-Rb44 cell strains under various TPT concentrations. IC50 values were calculated. Flow cytometry was used to detect the effects of various TPT concentrations on HXO-Rb44 cell apoptosis. Western blotting was used to detect the differences of Livin and PTEN protein expressions during cell apoptosis. Results The positive expressions of Livin and PTEN in the RB group were obviously different from those in the normal control group. In RB tissue, Livin expression was relevant to PTEN expression. TPT could significantly induce the occurrence of cell apoptosis and had a dependent relationship with drug concentration. Livin and PTEN expression levels varied with the extension of the effect time of TPT based on Western blotting analysis. Conclusions Livin and PTEN have high and low expression levels in the RB tissue, respectively. Both of them have key roles in RB occurrence and development. TPT could induce human RB cell strain HXO-Rb44 cell apoptosis, and its mechanism is associated with the inhibition of Livin and PTEN expressions.

关键词： retinocytoma Livin PTEN immunohistochemistry flow cytometry, Western blotting

Post-dilatation improves stent apposition in patients with ST-segment elevation myocardial infarction receiving primary percutaneous intervention: A multicenter, randomized controlled trial using optical coherence tomography

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World Journal of Emergency Medicine 2020年第2期11卷 87-92页

作者： Jun Jiang nai-liang Tian Han-bin Cui Chang-ling Li Xian-bao Liu Liang Dong Yong Sun Xiao-min Chen Shao-liang Chen Bo Xu Jian-an Wang Department of Cardiology the Second Affi liated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Cardiology Nanjing First HospitalNanjingChina Department of Cardiology Ningbo First HospitalNingboChina Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesBeijingChina

BACKGROUND: Stent failure is more likely in the lipid rich and thrombus laden culprit lesions underlying ST-segment elevation myocardial infarction(STEMI).This study assessed the effectiveness of post-dilatation in primary percutaneous coronary intervention(pPCI) for acute ***: The multi-center POST-STEMI trial enrolled 41 consecutive STEMI patients with symptom onset 16 atm *** apposition and coverage were evaluated by optical coherence tomography(OCT) after intracoronary verapamil administration via thrombus aspiration catheter, post pPCI and at 7-month *** primary endpoint was rate of incomplete strut apposition(ISA) at 7 months after ***: There were similar baseline characteristics except for stent length(21.9 [SD 6.5] mm vs.26.0 [SD 5.8] mm, respectively, P=0.03).In post-dilatation *** group, ISA rate was lower(2.5% vs.4.5%, P=0.04) immediately after pPCI without affecting final TIMI flow 3 rate(95.2% vs.95.0%, P>0.05) or corrected TIMI frame counts(22.6±9.4 vs.22.0±9.7, P>0.05); and at 7-month follow-up(0.7% vs.1.8%, Phe primary study endpoint, with similar strut coverage(98.5% vs.98.4%, P=0.63) and 1-year rate of major adverse cardiovascular events(MACE).CONCLUSION: In STEMI patients, post-dilatation after stent implantation and thrombus aspiration improved strut apposition up to 7 months without affecting coronary blood flow or 1-year MACE *** and longer term studies are warranted to further assess safety(Clinical *** identifier: NCT02121223).

关键词： ST-segment elevation myocardial infarction Post-dilatation Incomplete strut apposition Optical coherence tomography

Induction and Characterization of Laboratory Mutants of Phytophthora capsici Resistant to Dimethomorph and Flumorph

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Agricultural Sciences in China 2005年第10期4卷 752-759页

作者： YUAN Shan-kui LIU Xi-li GU bao-gen DONG Jin JIANG Hui SI nai-guo Department of Plant Pathology College of Agronomy and Biotechnology China Agricultural University Beijing 100094 P.R.China Center of Agrochemicals for Biological and Environmental Technology Institute for the Control ofAgrochemicals Ministry of Agriculture Beijing 100026 P.R.China Temasek Life Sciences Laboratory National University of Singapore Singapore 117604 Singapore Shenyang Research Institute of Chemical Industry Shenyang 110021 P.R.China

Laboratory studies were conducted to evaluate the risk of Phytophthora capsici developing resistance to two morphlines, dimethomorph and flumorph. Metalaxyl, the well-known high risk of resistance fungicides, was used as reference fungicide. Resistant mutants for the three fungicides were isolated by treating mycelium with ultraviolet radiation. Metalaxyl-resistant mutants were obtained with high frequency and exhibited high level of resistance with factors more than 100 folds, while mutation frequency for dimethomorph-resistance was relatively low and the resistance factors ranged from 3.0 to 13.9 folds. Most dimethomorph-resistant mutants decreased in hyphal growth rate and the spoulation ability, which have a large impact upon the epidemic development of dimethomorph-resistant populations. These results suggested that the risk of resistant pathogen population was much lower for dimethomorph than for metalaxyl. Both the frequency of developing resistance and level of resistance （resistance factors = 1.8-14.6） to dimethomorph were similar to those of its structure analogue flumorh. Moreover, the cross-resistance were found between them, which suggested the risks of developing resistance to dimethomorph and flumorph in the pathogen were very closely related. As P. capsici can potentially develop resistance to dimethomorph and flumorph, and oomycetes usually have the high risk to develop resistance to fungicides, appropriate management against resistance development should be taken.

关键词： Phytophthora capsici Resistance Dimethomorph Flumorph Metalaxyl

电解槽内异型凸台对电解质/铝液界面波动的影响

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东北大学学报（自然科学版） 2011年第5期32卷 704-707页

作者：贺铸李宝宽王芳冯乃祥东北大学材料与冶金学院辽宁沈阳110819

针对铝电解槽内电解质/铝液界面的波动现象,基于计算流体动力学(CFD)的方法建立了铝电解槽内电解质/铝液两相流体流动的数学模型.使用Fluent软件的流体体积自由面跟踪法和自定义函数,研究了阴极凸台对电解质/铝液界面波动的影响.结果表... 详细信息

针对铝电解槽内电解质/铝液界面的波动现象,基于计算流体动力学(CFD)的方法建立了铝电解槽内电解质/铝液两相流体流动的数学模型.使用Fluent软件的流体体积自由面跟踪法和自定义函数,研究了阴极凸台对电解质/铝液界面波动的影响.结果表明,异型凸台的加入使得两相界面的波动幅度降低了17.2%,但凸台的存在同时也使得熔体对侧部槽帮冲刷增强.

关键词：铝电解槽界面波动异型凸台两相流动计算流体动力学

Development of an automatic monitoring system for rice light-trap pests based on machine vision

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Journal of Integrative Agriculture 2020年第10期19卷 2500-2513页

作者： YAO Qing FENG Jin TANG Jian XU Wei-gen ZHU Xu-hua YANG bao-jun LU Jun XIE Yi-ze YAO Bo WU Shu-zhen KUAI nai-yang WANG Li-jun School of Information Science and Technology Zhejiang Sci-Tech UniversityHangzhou 310018P.R.China State Key Laboratory of Rice Biology China National Rice Research InstituteHangzhou 310006P.R.China Plant Protection Quarantine and Pesticide Management Station of ZhejiangHangzhou 310020P.R.China Zhejiang Top Cloud-agri Technology Co Ltd.Hangzhou 310015P.R.China Agricultural Technology Extension Center of Shangyu Shaoxing 312300P.R.China Agricultural Technology Extension Center of Keerqin Keerqin 137713P.R.China

Monitring pest populations in paddy fields is important to effectively implement integrated pest *** traps are widely used to monitor field pests all over the *** conventional light traps still involve manual identification of target pests from lots of trapped insects,which is time-consuming,labor-intensive and error-prone,especially in pest peak *** this paper,we developed an automatic monitoring system for rice light-trap pests based on machine *** system is composed of an itelligent light trap,a computer or mobile phone client platform and a cloud *** light trap firstly traps,kills and disperses insects,then collects images of trapped insects and sends each image to the cloud *** target pests in images are automatically identifed and counted by pest identification models loaded in the *** avoid light-trap insects piling up,a vibration plate and a moving rotation conveyor belt are adopted to disperse these trapped *** was a close correlation(r=0.92)between our automatic and manual identification methods based on the daily pest number of one-year images from one light *** experiments demonstrated the effectiveness and accuracy of our automatic light trap monitoring system.

关键词： automatic monitoring system light trap rice pest machine vision image processing convolutional neural network

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算法教学策略初探

中国教育学刊 2005年第5期 41-44页

作者：宋宝和宋乃庆西南师范大学

算法是数学的重要组成部分,是计算科学的重要基础。算法教学策略的实验结果表明:数学教师比计算机教师讲授算法具有明显优势,二者协调配合进行教学更为有效;教学重点是对算法概念实质的理解,对算法思想的感受,对程序框图的正确设计;教... 详细信息

算法是数学的重要组成部分,是计算科学的重要基础。算法教学策略的实验结果表明:数学教师比计算机教师讲授算法具有明显优势,二者协调配合进行教学更为有效;教学重点是对算法概念实质的理解,对算法思想的感受,对程序框图的正确设计;教学难点在于程序框图的正确设计,赋值语句、循环语句的理解。算法教学的策略主要是:数学教师讲授算法内容;数学教师加强计算机知识和技术的修养;计算机教师做好算法教学的协助配合工作;消除学生对算法概念及算法表达形式的神秘感和畏难心理;鼓励和引导学生自我构建算法;加强校本教研。

关键词：算法教学策略实验

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基于随机模拟和滤波分析的大群体决策方法

控制与决策 2019年第8期34卷 1761-1768页

作者：韦保磊谢乃明南京航空航天大学经济与管理学院南京211106 南京航空航天大学灰色系统研究所南京211106

基于决策者评价信息包含主观成分与客观成分的基本假设,将随机模拟与滤波分析方法相结合,提出随机滤波决策方法分离主客观成分,运用大数定律分析以客观成分均值作为方案排序标准的理论基础与物理意义,论证该方法的收敛性及其在解决大群... 详细信息

基于决策者评价信息包含主观成分与客观成分的基本假设,将随机模拟与滤波分析方法相结合,提出随机滤波决策方法分离主客观成分,运用大数定律分析以客观成分均值作为方案排序标准的理论基础与物理意义,论证该方法的收敛性及其在解决大群体决策问题中的优势.以经验模态分解为滤波方法构建大群体随机经验模态分解滤波决策方法,并运用算例说明决策过程,以验证方法的合理性和有效性.

关键词：大群体决策随机模拟滤波分析主客观成分信息集结经验模态分解

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横向偏置场作用的非晶带巨磁阻抗效应理论

物理学报 2011年第3期60卷 666-671页

作者：鲍丙豪任乃飞骆英江苏大学机械工程学院江苏大学理学院镇江212013

采用多畴结构模型,考虑非晶带具有180°畴壁的磁畴及其两面的偏置磁场方向的不同,根据自由能最小原理,Maxwell方程组及带阻尼项的Landau-Lifshitz方程,建立了非晶态合金带在横向偏置磁场作用下的巨磁阻抗效应的理论计算公式.提出并采用... 详细信息

采用多畴结构模型,考虑非晶带具有180°畴壁的磁畴及其两面的偏置磁场方向的不同,根据自由能最小原理,Maxwell方程组及带阻尼项的Landau-Lifshitz方程,建立了非晶态合金带在横向偏置磁场作用下的巨磁阻抗效应的理论计算公式.提出并采用四状态平均磁导率代替单畴模型获得的磁导率,得到了更符合实际的处于偏置场作用的阻抗随外磁场变化的理论结果.

关键词：偏置磁场四状态多畴结构巨磁阻抗