检索结果-南通市图书馆

视神经脊髓炎高危综合征患者血清尿酸水平与临床特征的相关性

在线全文

学校读者我要写书评

暂无评论

中华神经科杂志 2011年第2期44卷 109-112页

作者：尤小凡秦伟郝咏刚赵文慧叶静胡文立首都医科大学附属北京朝阳医院神经内科 100020 首都医科大学宣武医院神经内科

目的探讨视神经脊髓炎高危综合征患者血清尿酸水平与临床特征的关系.方法尿酶法检测51例急性期视神经脊髓炎高危综合征（34例长节段脊髓炎,17例视神经炎）,48例视神经脊髓炎,45例神经科其他疾病,65名健康对照的血清尿酸水平.采用扩展... 详细信息

目的探讨视神经脊髓炎高危综合征患者血清尿酸水平与临床特征的关系.方法尿酶法检测51例急性期视神经脊髓炎高危综合征（34例长节段脊髓炎,17例视神经炎）,48例视神经脊髓炎,45例神经科其他疾病,65名健康对照的血清尿酸水平.采用扩展残疾状态量表（EDSS）评价病情严重程度,MRI评估受累病灶,细胞免疫荧光法检测水通道蛋白4抗体水平.结果长节段脊髓炎组尿酸水平（189.84±85.65）μmol/L,视神经炎组（222.12±61.68）μmol/L,低于其他疾病组[（315.90±71.36）μmol/L]和健康对照组[（291.05±76.64）μmol/L,P＜0.01],与视神经脊髓炎[（219.19±76.47）μmol/L]比较差异无统计学意义.各组女性患者尿酸水平[（158.24±55.92）、（187.00±47.52）、（198.21±62.62）、（274.51±70.66）和（243.26±60.65）μmol/L]均低于男性组[（262.09±101.63）、（262.45±62.13）、（298.90±74.14）、（355.37±50.30）和（340.34±58.23）μmol/L,t=3.183、2.578、4.356、4.365、6.579,P＜0.05].高危综合征组患者不同病程组,水通道蛋白4抗体阳性、阴性组尿酸差异无统计学意义.长节段脊髓炎组尿酸水平与EDSS评分呈负相关（r=-0.714,P＜0.01）.结论低尿酸可能与视神经脊髓炎高危综合征发病相关,且与长节段脊髓炎患者疾病严重程度有关.

关键词：视神经脊髓炎尿酸脊髓炎,横贯性

Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 447-462页

作者： haonan Zhang Cheng hao Tongtong Fu Dian Yu Jane Howe Kaiwen Chen Ning Yan hao Ren Huamin Zhai Jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada Department of Materials Science and Engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2)T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 1273 mF cm^(−2)(241 F g^(−1))and 514 mF cm^(−2)(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

丙泊酚静脉麻醉对老年患者心率和血糖变化的影响

在线全文

学校读者我要写书评

暂无评论

糖尿病新世界 2015年第22期35卷 62-64页

作者：郝涌刚王善秋重庆医科大学附属第一医院麻醉科重庆400016

目的探析老年病人进行丙泊酚静脉麻醉对其血糖及心率的影响。方法选择该院2014年4月—2015年4月予以上腹部手术老年病人80例,根据随机数字表法分为研究组、对照组,每组40例,研究组进行丙泊酚静脉麻醉,对照组进行瑞芬太尼静脉麻醉法,比... 详细信息

目的探析老年病人进行丙泊酚静脉麻醉对其血糖及心率的影响。方法选择该院2014年4月—2015年4月予以上腹部手术老年病人80例,根据随机数字表法分为研究组、对照组,每组40例,研究组进行丙泊酚静脉麻醉,对照组进行瑞芬太尼静脉麻醉法,比较两组围麻醉期不同时间点的心率及血糖水平变化情况等临床参数指标。结果研究组麻醉诱导前(T0)、给药后5 min(T1)、切皮后1 h(T2)、术毕(T3)的心率(HR)情况显著优于对照组,差异有统计学意义(P<0.05);研究组麻醉诱导前、给药5 min(T1)、切皮后1 h(T2)、术毕(T3)时段的血糖水平显著优于对照组,差异有统计学意义(P<0.05)。结论老年手术病人进行丙泊酚静脉麻醉,病人围手术期的心率及血糖水平变化平稳,效果确切,值得临床推广。

关键词：麻醉影响心率血糖静脉麻醉丙泊酚老年患者

在线全文

学校读者我要写书评

暂无评论

间位芳纶/LFR紧密纺纱技术的研发

高科技纤维与应用 2009年第4期34卷 24-27页

作者：郝永刚段胜伟德州华源生态科技有限公司山东德州253000 西湖科技有限公司杭州办事处杭州310012

介绍了间位芳纶和LFR的性能特点,分析、改进了间位芳纶/LFR紧密纺纱的工艺流程和技术要点:前纺时并条工序应采用较小定量,开清棉工序宜采用"短流程、少抓勤抓和多松少打"原则等多项技术措施;后道细纱工序时优选集聚张力为1.05,集聚气流... 详细信息

介绍了间位芳纶和LFR的性能特点,分析、改进了间位芳纶/LFR紧密纺纱的工艺流程和技术要点:前纺时并条工序应采用较小定量,开清棉工序宜采用"短流程、少抓勤抓和多松少打"原则等多项技术措施;后道细纱工序时优选集聚张力为1.05,集聚气流压力高于常规8%～10%和负压值约1300kPa时纤维的积聚效果最好,对积聚前胶辊进行防静电处理,可消除绕花现象。结果表明,紧密纺纱的成纱质量和生产效率都得到了提高,充分体现其优越性。

关键词：间位芳纶 LFR 紧密纺工艺改进

5例肺动脉血栓内膜剥脱术后神经系统障碍的临床特点及原因

在线全文

学校读者我要写书评

暂无评论

中华胸心血管外科杂志 2011年第7期27卷 416-419页

作者：郝咏刚顾松翟英慧胡文立杨媛华首都医科大学附属北京朝阳医院神经内科首都医科大学附属北京朝阳医院心脏外科首都医科大学附属北京朝阳医院呼吸与危重症医学科北京市普仁医院内科

目的总结5例肺动脉血栓内膜剥脱术治疗慢性肺动脉血栓栓塞症术后神经系统障碍的患者的临床表现特点，并尝试分析其原因。方法回顾2002年至2010年，26例因慢性血栓栓塞性肺动脉高压症行肺动脉血栓内膜剥脱术的患者围手术期资料。总结术... 详细信息

目的总结5例肺动脉血栓内膜剥脱术治疗慢性肺动脉血栓栓塞症术后神经系统障碍的患者的临床表现特点，并尝试分析其原因。方法回顾2002年至2010年，26例因慢性血栓栓塞性肺动脉高压症行肺动脉血栓内膜剥脱术的患者围手术期资料。总结术后生泵患者中5例出现神经功能障碍并发症者的临床与影像学特点，分析其与无并发症患者的手术前、手术中的资料，寻找可能的影响因素。结果26例中围手术期死亡4例，22例生存者心功能改善，生活质量明显提高。5例围手术期出现神经系统障碍表现者中，3例表现为嗜睡、谵妄、记忆力障碍，颅脑CT未见异常发现，治疗后症状1周内消失，2周内完全恢复；另2例患者除上述症状外，还表现为共济失调、步态不稳、舞蹈样动作，症状持续时间长，其中1例经高压氧治疗后1个月症状好转，颅脑CT未见异常发现，颅脑MRI显示双侧中脑，基底节区异常信号，治疗8周症状基本好转出院，6个月症状完全消失，复查颅脑MRI异常信号消失；1例颅脑CT未见异常发现，12周出院，恢复较差，生活部分自理。术后出现神经系统障碍患者Jamieson手术分型Ⅲ型、Ⅳ型比例较多（P=0．024），手术中停循环时间较长（P=0．034）。结论肺动脉血栓内膜剥脱术后早期神经系统障碍多表现为弥漫性脑皮层与对称性基底节区神经功能障碍，颅脑MRI相应区域异常信号，多数患者症状在2—8周内消失，6个月内颅脑MRI异常信号可以消失。出现神经系统功能障碍的患者多手术操作难度大，停循环时间较长，推测考虑与术中脑缺血缺氧有关。

关键词：肺动脉血栓内膜剥脱术后神经系统临床特点高压氧治疗颅脑MRI 肺动脉血栓栓塞症神经系统功能障碍神经功能障碍

Laser‑Induced Highly Stable Conductive Hydrogels for Robust Bioelectronics

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第3期17卷 117-120页

作者： Yibo Li hao Zhou Huayong Yang Kaichen Xu State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310058People’s Republic of China

Despite the promising progress in conductive hydrogels made with pure conducting polymer,great challenges remain in the interface adhesion and robustness in longterm *** address these challenges,*** Hwan Ko and Taek-Soo Kim’s team introduced a laserinduced phase separation and adhesion method for fabricating conductive hydrogels consisting of pure poly(3,4-ethylenedioxythiophene):polystyrene sulfonate on polymer *** laser-induced phase separation and adhesion treated conducting polymers can be selectively transformed into conductive hydrogels that exhibit wet conductivities of 101.4 S cm^(−1)with a spatial resolution down to 5μ***,they maintain impedance and charge-storage capacity even after 1 h of *** micropatterned electrode arrays demonstrate their potential in long-term in vivo signal recordings,highlighting their promising role in the field of bioelectronics.

关键词： Laser processing Conductive hydrogels Stable interface Bio-interfacing electrodes Bioelectronic application

在线全文

学校读者我要写书评

暂无评论

南昌市构建BRT系统的必要性分析

交通标准化 2009年第3期37卷 219-222页

作者：郝勇刚查伟雄华东交通大学交通运输与经济研究所江西南昌330013

BRT是一种经济、高效、新型的以"公交优先"为核心思想的城市公共交通模式。通过对南昌市公交现状和公交系统存在的问题进行分析,结合国内外城市运用BRT的成功经验,对南昌市应尽快修建BRT的原因加以阐述,最后提出南昌市发展BRT的一些建议... 详细信息

BRT是一种经济、高效、新型的以"公交优先"为核心思想的城市公共交通模式。通过对南昌市公交现状和公交系统存在的问题进行分析,结合国内外城市运用BRT的成功经验,对南昌市应尽快修建BRT的原因加以阐述,最后提出南昌市发展BRT的一些建议,对南昌市BRT系统的建设具有重要意义。

关键词： BRT 南昌市必要性公交优先

Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan Li Peng hao Hongmei Duan Fei hao Wen Zhao Yudan Gao Zhaoyang Yang Kwok-Fai So Xiaoguang Li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

Optimizing battery deployment: Aging trajectory prediction enabling homogenous performance grouping

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 565-577页

作者： Shuquan Wang Feng Gao Zhan Ma hao Tian Yusen Zhang School of Control Science and Engineering Shandong University Key Lab of Power System Intelligent Dispatch and Control of Ministry of Education Shandong University

As battery deployments in electric vehicles and energy storage systems grow, ensuring homogeneous performance across units is crucial. We propose a multi-derivative imaging fusion(MDIF) model, employing advanced imaging and machine learning to predict battery aging trajectories from minimal initial data, thus facilitating effective performance grouping before deployment. Utilizing a derivative strategy and Gramian Angular Difference Field for dimensional enhancement, the MDIF model uncovers subtle predictive features from discharge curve data after only ten cycles. The architecture includes a parallel convolutional neural network with lateral connections to enhance feature integration and *** on a self-developed dataset, the model achieves an average root-mean-square error of 0.047 Ah and an average mean absolute percentage error of 1.60%, demonstrating high precision and *** robustness is further validated through transfer learning on two publicly available datasets, adapting with minimal retraining. This approach significantly reduces the testing cycles required, lowering both time and costs associated with battery testing. By enabling precise battery behavior predictions with limited data, the MDIF model optimizes battery utilization and deployment strategies, enhancing system efficiency and sustainability.

关键词： Lithium-ion battery Battery prognostics Fusion model Convolutional neural network Transfer learning