检索结果-南通市图书馆

Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2023年第7期22卷 2188-2199页

作者： XU Kui ZHOU Yan-rong SHANG Hai-tao XU Chang-jiang TAO Ran hao wan-jun LIU Sha-sha MU Yu-lian XIAO Shao-bo LI Kui State Key Laboratory of Animal Nutrition/Key Laboratory of Animal Genetics Breeding and Reproduction of Ministry of Agriculture and Rural AffairsInstitute of Animal SciencesChinese Academy of Agricultural SciencesBeijing 100193P.R.China Shenzhen Kingsino Technology Co. Ltd.Shenzhen 518106P.R.China State Key Laboratory of Agricultural Microbiology/Key Laboratory of Preventive Veterinary Medicine in Hubei Province College of Veterinary MedicineHuazhong Agricultural UniversityWuhan 430070P.R.China Precision Medicine Institute The First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080P.R.China

Porcine reproductive and respiratory syndrome(PRRS)is recognized as one of the most infectious viral diseases of *** Cluster of differentiation 163(CD163)is identified as an essential receptor for mediating PRRS virus(PRRSV)infection,the important residues involved in infection on CD163 are still ***,it is very important to identify these key residues to study the mechanism of PRRSV infection and to generate anti-PRRSV *** this study,we first generated immortalized porcine alveolar macrophage(IPAM)cell lines harboring 40-residues(residues 523-562,including R561(arginine(R)at position 561))deletion of *** infection experiments showed that these IPAM cell lines were completely resistant to PRRSV *** then generated cloned pigs carrying CD163-R561A(an arginine(R)to alanine(A)substitution at position 561 of CD163).PRRSV challenge experiments in porcine alveolar macrophages(PAMs)isolated from the CD163-R561A pigs showed significantly lower susceptibility to PRRSV than that of CD163-R561 *** this study,we show that CD163523-562 contains essential residues for mediating PRRSV infection,and that CD163 R561 significantly contributes to PRRSV infection but is not essential for *** functional sites can therefore serve as new targets for understanding the mechanism of PRRSV ***,CD163-R561A pigs can be used as an important model for improving pig germplasm with resistance against PRRSV.

关键词： pigs porcine alveolar macrophages dual-sgRNA homology-directed repair PRRSV CD163

Al掺杂对Li(Al_yCo_(1-y))O_2材料结构的影响

在线全文

学校读者我要写书评

暂无评论

高等学校化学学报 2001年第2期22卷 175-178页

作者：郝万君陈岗史延慧吉林大学材料科学系长春130023

报道了在 80 0℃烧结制备的新型锂二次电池正极材料Li(AlyCo1-y)O2 (y =0 ,0 .11)的X射线衍射结果和由此而揭示的结构演化过程 .研究表明 ,y≤ 0 .5时 ,材料呈单相 ,0 .6≤ y≤ 0 .9时 ,材料呈两相[Li(AlyCo1-y)O2 ,γ LiAlO2 ]共存状态... 详细信息

报道了在 80 0℃烧结制备的新型锂二次电池正极材料Li(AlyCo1-y)O2 (y =0 ,0 .11)的X射线衍射结果和由此而揭示的结构演化过程 .研究表明 ,y≤ 0 .5时 ,材料呈单相 ,0 .6≤ y≤ 0 .9时 ,材料呈两相[Li(AlyCo1-y)O2 ,γ LiAlO2 ]共存状态 ,y =1时 ,材料又呈单相 ,为γ LiAlO2 相 .Li(AlyCo1-y)O2 材料中y值的上限即Al的最大固溶度在 0 .5左右 .在单相区 (y≤ 0 .5 ) ,随着Al掺杂的增多 ,Li(AlyCo1-y)O2 材料晶格结构参数发生变化 ,a轴缩短 ,c轴变长 ,c/a比基本呈线性增加 ,材料的层状属性更加明显 .

关键词：正极材料 XRD 结构锂二次电池钴酸锂铝掺杂

Optimizing electronic structure through point defect engineering for enhanced electrocatalytic energy conversion

在线全文

学校读者我要写书评

暂无评论

Green Energy & Environment 2025年第1期10卷 109-131页

作者： Wei Ma Jiahao Yao Fang Xie Xinqi wang hao wan Xiangjian Shen Lili Zhang Menggai Jiao Zhen Zhou Interdisciplinary Research Center for Sustainable Energy Science and Engineering(IRC4SE2) School of Chemical EngineeringZhengzhou UniversityHenan450001China

Point defect engineering endows catalysts with novel physical and chemical properties,elevating their electrocatalytic *** introduction of defects emerges as a promising strategy,effectively modifying the electronic structure of active *** optimization influences the adsorption energy of intermediates,thereby mitigating reaction energy barriers,altering paths,enhancing selectivity,and ultimately improving the catalytic efficiency of *** elucidate the impact of defects on the electrocatalytic process,we comprehensively outline the roles of various point defects,their synthetic methodologies,and characterization ***,we consolidate insights into the relationship between point defects and catalytic activity for hydrogen/oxygen evolution and CO_(2)/O_(2)/N_(2) reduction reactions by integrating mechanisms from diverse *** underscores the pivotal role of point defects in enhancing catalytic *** last,the principal challenges and prospects associated with point defects in current electrocatalysts are proposed,emphasizing their role in advancing the efficiency of electrochemical energy storage and conversion materials.

关键词： Point defect engineering Doping Vacancy Electrocatalysis Electronic structure

锂电池阴极材料Li(Co_xAl_(1-x))O_2的溶胶-凝胶法合成及表征

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高等学校化学学报 2000年第4期21卷 497-500页

作者：史延慧郝万君陈岗冯守华教育部无机合成与制备化学开放研究实验室吉林大学材料科学系长春130023

采用溶胶 -凝胶方法合成了锂二次电池阴极材料 Li( Cox Al1 - x) O2 ,并采用 XRD方法分析了材料的相变过程、烧结时间对材料合成的影响及不同 Al/Co比掺杂对材料相变的影响 ,并进行了结构表征 .研究表明 ,材料结构随 Al固溶度的增大及... 详细信息

采用溶胶 -凝胶方法合成了锂二次电池阴极材料 Li( Cox Al1 - x) O2 ,并采用 XRD方法分析了材料的相变过程、烧结时间对材料合成的影响及不同 Al/Co比掺杂对材料相变的影响 ,并进行了结构表征 .研究表明 ,材料结构随 Al固溶度的增大及温度的升高呈现出 a轴缩短 ,c轴伸长的趋势 .材料晶相稳定温度在60 0～ 90 0℃之间 ,烧结时间在 3

关键词：锂电池阴极材料溶胶-凝胶 Li(CoxAl1-x)O2

Variable Pitch Sliding Mode Control of Wind Turbine Based on Disturbance Observer

在线全文

学校读者我要写书评

暂无评论

Variable Pitch Sliding Mode Control of Wind Turbine Based on...

第30届中国控制与决策会议

作者： hao wan-jun hao shi-yuan Jia yi-shi Chen xin-jing Cao song-qing Qiao yan-hui Li zhe College of Electronic and Information Engineering Suzhou University of Science and Technology Department of Electrical Engineering Technical University of Denmark College of Mechanical Engineering Suzhou University of Science and Technology

Due to the randomness of the wind speed, the time variability of the wind turbine’s parameters, the nonlinearity of the system and the time delay, the output power of the wind turbine is unstable. In order to improve the dynamic performance of the system in the constant power output operation area, based on the analysis of the research status of variable pitch control of wind power generation system, a sliding mode control scheme based on disturbance observer is proposed. This method not only has the robustness for sliding mode control parameters also has many advantages such as fast response. Adding the disturbance observer is effective to restrain the external disturbance of the system, ensuring the stability of the output power and the motor speed of the wind generator system under the condition of random wind speed disturbance. The results show that the variable pitch sliding mode controller based on disturbance observer has good dynamic performance and robustness to wind speed disturbance, which can effectively improve the pitch control effect of the system.

关键词： wind power generation system pitch angle control disturbance observer sliding mode control

孤岛微电网异构电池储能系统的分布式有限时间次级控制

在线全文

cnki会议

学校读者我要写书评

暂无评论

控制与决策 2021年第8期36卷 2034-2041页

作者：许德明李泽崔国增郝万君苏州科技大学电子与信息工程学院江苏苏州215009 苏州科技大学苏州智慧城市研究院江苏苏州215009 江苏省建筑智慧节能重点实验室江苏苏州215009

针对孤岛微电网异构电池储能系统频率、电压以及电池能量的一致性问题,考虑初级下垂控制,提出一种新的分布式有限时间次级控制策略.采用所提出的控制方案能够在有限时间内实现系统频率、电压恢复一致到额定值,并获得电池能量等级的均衡... 详细信息

针对孤岛微电网异构电池储能系统频率、电压以及电池能量的一致性问题,考虑初级下垂控制,提出一种新的分布式有限时间次级控制策略.采用所提出的控制方案能够在有限时间内实现系统频率、电压恢复一致到额定值,并获得电池能量等级的均衡一致和期望的有功功率分配.该控制方法的优势在于整定时间的上界独立于系统的任意初始条件,能够保证微电网有限时间控制的及时性,同时基于Lyapunov方法分析控制策略的一致性收敛特性.最后,通过Matlab/Simulink仿真实验,结果进一步佐证了分布式有限时间次级控制策略的有效性.

关键词：孤岛微电网电池储能系统一致性有限时间次级控制

在线全文

学校读者我要写书评

暂无评论

真空度对真空冷喷涂气固两相流的影响

表面技术 2015年第12期44卷 75-79,121页

作者：郑建新郝婉君河南理工大学机械与动力工程学院河南焦作454003

目的真空度直接影响着真空冷喷涂时气体流动特性和颗粒撞击速度,研究真空度对气体和颗粒流动特性的影响。方法确定真空冷喷涂系统结构,采用FLUENT软件进行真空冷喷涂气固两相流研究,通过数值模拟研究真空度对流场和颗粒撞击速度的影响,... 详细信息

目的真空度直接影响着真空冷喷涂时气体流动特性和颗粒撞击速度,研究真空度对气体和颗粒流动特性的影响。方法确定真空冷喷涂系统结构,采用FLUENT软件进行真空冷喷涂气固两相流研究,通过数值模拟研究真空度对流场和颗粒撞击速度的影响,并研究相同压力比下的气固两相流特性。结果当入口压力一定时,喷管内的气体轴线速度、密度和温度与环境压力大小无关;而在射流区,环境压力越小,则气体轴线速度波动越小、密度越低,但到达基板后的气体温度均接近喷管入口温度。环境压力对大粒径颗粒的撞击速度影响较大,颗粒撞击速度随环境压力增大而先增后减,最佳环境压力可根据气相云图和气体密度来确定。当进出口压力比相同时,喷管内和射流区域内的气相速度云图基本相同,气体轴线速度曲线基本重合,而基板前的颗粒速度不同,此时环境压力越低,颗粒速度越高,越有利于形成涂层。结论采用计算流体动力学分析方法厘清了真空度对真空冷喷涂气固两相流的影响,为涂层制备奠定了理论基础。

关键词：真空冷喷涂气固两相流真空度流场颗粒速度数值研究

A newly evolved chimeric gene confers cytoplasmic effects on seed oil content in polyploid rapeseed(Brassica napus L.)

在线全文

学校读者我要写书评

暂无评论

A newly evolved chimeric gene confers cytoplasmic effects on...

中国作物学会油料作物专业委员会第八次会员代表大会暨学术年会

作者： LIU jun hao wan-jun LIU Jing FAN Shi-hang Zhao Wei DENG Lin-bing wanG Xin-fa HU Zhi-yong HUA Wei wanG Han-zhong Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences Key Laboratory of Biology and Genetic Improvement of Oil CropsMinistry of Agriculture

Cytoplasmic effects(CE) are discovered to influence a diverse array of agronomic traits in crops,and understanding the nature can help accelerate breeding *** oil content(SOC) is of great agricultural,nutritional and economic ***,the molecular basis of CE on SOC(CE-SOC) remain *** we employ an optimized approach to sequence cytoplasmic(plastid and mitochondria) genomes of allotetraploid oilseed rape(Brassica napus L.) lines 51218 and 56366 that bears contrasting *** combining comparative genomics and genome-wide transcriptome analysis,we identify mitochondria-encoded ORF188 as a potential CE-SOC determinant *** transgenic analyses in the model system Arabidopsis thaliana and rapeseed indicate that ORF188 governs CE-SOC and can significantly increase SOC,strikingly,through promoting yield of *** transcriptional profiling with microarray and RNA-Seq consistently reveal transcriptional reprogramming of the mitochondria energy metabolic pathways to facilitate ATP ***,ORF188 is a newly formed chimeric gene in the evolution of genetic novelty that endows rapeseed with positive *** results sheds first light on the genetic basis of CE contributing to a key quantitative trait in polyploidy crops and enrich theory on maternal control of oil content,providing new scientific guidance for creation of high-oil germplasm resources.

关键词： cytoplasmic effects seed oil content energy metabolism crop breeding Brassica napus

Robust Fuzzy Control for Uncertain Nonlinear System based on Multi-objective Optimization

在线全文

cnki会议

学校读者我要写书评

暂无评论

Robust Fuzzy Control for Uncertain Nonlinear System based on...

第24届中国控制与决策会议

作者： hao wan-jun, Qiao yan-Hui, Zhu Xue-Li, Wu yong Zhi, Li Ze Suzhou University of sience and tecnology, Suzhou 215011, china

This paper deals with the problem of robust control for Uncertain Nonlinear System via fuzzy control approach. First, a fuzzy controller with robust control capability is proposed. For avoiding complex controller parameters adjustment, Multi-objective particle swarm Optimization (PSO) algorithm is adopted during the controller design. Secondly, the multi-model is employed to represent the nonlinear system with norm-bounded parameter uncertainties. Finally, a simulation example illustrates the effectiveness and the feasibility of the proposed approach.

关键词： Fuzzy Control Uncertain Nonlinear System Robust Performance Multi-objective Optimization