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内燃机与配件 2021年第21期 3-4页

作者：白军爱王旭兰王红丽郝勇刚李元石中国北方发动机研究所天津300405

应用Excite_TD软件,对某发动机配气机构进行运动学和动力学分析,保证气门良好、准确、平稳的运动规律下,重新设计了凸轮型线,优化后的凸轮型线,经过发动机试验验证,具有良好的运动学和动力学特性。

关键词：配气机构凸轮型线运动学动力学

脑白质疏松症患者执行功能障碍的弥散张量成像研究

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中华老年医学杂志 2012年第3期31卷 200-204页

作者：王双坤袁俊亮郝咏刚李淑娟胡文立郭晓娟刘敏顾华张慧博彭朋首都医科大学附属北京朝阳医院放射科 100020 首都医科大学附属北京朝阳医院神经内科 100020

目的应用弥散张量成像（DTI）技术探讨脑白质疏松症（LA）患者脑白质微结构的改变与执行功能障碍的关系。方法对23例LA患者和19例健康对照进行蒙特利尔认知评估（MoCA）和4项执行功能测验包括Stroop色词干扰测验、连线测验（TMT）、数... 详细信息

目的应用弥散张量成像（DTI）技术探讨脑白质疏松症（LA）患者脑白质微结构的改变与执行功能障碍的关系。方法对23例LA患者和19例健康对照进行蒙特利尔认知评估（MoCA）和4项执行功能测验包括Stroop色词干扰测验、连线测验（TMT）、数字符号测验（DST）、言语流畅性测验（VF），行DTI扫描，测量LA患者病灶区（WML）、LA患者正常表现白质区（NAWM）、对照组半卵圆中心、脑室前后部周围白质区的各向异性值（FA）、表观扩散系数（ADC）、平均扩散率（MD），并对LA组白质参数与认知功能进行相关性分析。结果LA患者存在明显的执行功能障碍，LA患者在Stroop色词干扰测验B、Stroop色词干扰测验C和Stroop色词干扰测验C—B、TMT—A和TMT—B、DST行为学成绩均较对照组相应测验值差[（69．4±13．4）和（43．3±5．0），t=8．03，P〈0．05]、[（141．4±42．1）和（65．4±10．3），t=7．66，P〈0．05]、[（72．0±41．4）和（22．1±9．6），t=5．13，P〈0．053、[（73．2±15．3）和（31．2±7．2），t=10．97，P〈0．05]、[（125．6±18．0）和（81．6±5．9），t=10．22，P〈0．05]和[（24．8±5．6）和（36．8±5．1），t=7．19，P〈0．053。WML在半卵圆中心、脑室前部和后部FA显著低于NAWM与对照组的相应区域的检验值[（0．2±0．1），（0．4±0．1）和（0．4±0．1），F=45．08，P〈0．05]、[（0．2±0．0），（0．4±0．1）和（0．4±0．1），F=70．11，P〈0．053和[（0．3±0．1），（0．4±0．1）和（0．4±0．1），F=8．54，P〈0．053；而WML在半卯圆中心、脑室前部和后部ADC显著高于NAWM和对照组的相应区域的检验值[（1．2±0．2），（O．8±0．1）和（0．8±0．1），F=46．77，P〈0．05]、[（1．2±0．3），（0．8±0．0）和（0．8±0．1），F=68．22，P〈0．05]和[（1．4±0．3），（0．8±0．0）和（0．9士0．1），F=17．08，P〈0．053；WML在半卵圆中心、脑室前部和后部MD显著高于NAWM和对照组的相应区域的检验值[（127．8±14．5），（95．3±26．4）和（100．8±9．4），F=19．72，P〈0．053、[（127．4±16．0），（101．8±13．9）和（93．4±5．6），F=39．26，P〈0．05]和[（134．4±21．2），（114．8±14．5）和（114．4±11．7），F=10．66，P〈0．05]。相关性分析得出LA患者脑室前角旁白质FA与Stroop C—B（r=0．46，P〈0．05）、TMT—A（r=0．48，P〈0．05）和TMT—B（r=0．46，P〈O．05）呈负相关，与DST测验呈正相关（r=0．42，P〈0．05）。结论DTI能够准确显示LA患者的特征性脑白质微结构的改变，且这种改变与执行功能密切相关。LA患者的执行功能障碍可能与前额叶一皮层下环路功能受损有关。

关键词：脑白质疏松症认知磁共振成像弥散

Synthesis, Structure and DFT Investigation into a Copper(II) Compound Consisting of 4,7-diphenyl-1,10-phentheanthroline

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Chinese Journal of Structural Chemistry 2005年第12期24卷 1375-1380页

作者： LI hao-Hong CHEN Zhi-Rong REN yong-gang LI Jun-Qian HUANG Chang-Cang Zhao Bin College of Chemistry and Chemical Engineering Fuzhou University Fuzhou Fujian 350002 China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterThe Chinese Academy of SciencesFuzhou Fujian 35002 China

The copper（Ⅱ） DPP adduct Cu（DPP）（DMF）2（H2O）-（ClO4）2 1 （DPP = 4,7-diphenyl-1, 10-phentheanthroline, DMF = N,N＇-dimethyl formamide） has been prepared by a direct synthetic method and structurally characterized. It presents a mononuclear structure and crystallizes in triclinic, space group P1 with a = 9.8717（2）, b = 12.579, c = 14.7574（2） A, α = 67.976（6）,β = 82.031（9）, γ = 80.343（9）°, V = 1668.96（9）A, Z = 1, Dc= 1.495 g/cm^3,/t（MoKα） = 0.877 mm^-1, F（000） = 774, C60H64Cl4Cu2N8O221 Mr = 1502.09, the final R1= 0.0643 and wR2 = 0.1799 for 6153 observed reflections with 1 〉 2σ（1）. Structure analysis shows that copper atom presents an unusual fivecoordination of square pyramid geometry. The whole structure is stabilized by π-π stacking interactions and static attractive forces from [ClO4]-anions. Based on crystal data, quantum chemistry calculation on DFF/B3LPY level was used to reveal the electronic structure of 1.

关键词： Cu(Ⅱ) complexes 4,7-diphenyl-1,10-phentheanthroline DFT calculation

Nucleotide Variation in the NCED3 Region of Arabidopsis thaliana and its Association Study with Abscisic Acid Content under Drought Stress

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Journal of Integrative Plant Biology 2009年第2期51卷 175-183页

作者： gang-Ping hao Xiu-Hai Zhang yong-Qin Wang Zhong-Yi Wu Cong-Lin Huang Beijing Agro-Biotechnology Research Center Beijing Academy of Agriculture and Forestry Sciences Beijing 100097 China Taishan Medical College Taian 271000 China

Drought tolerance is a comprehensive quantitative trait that is being understood further at the molecular genetic level. Abscisic acid （ABA） is the main drought-induced hormone that regulates the expression of many genes related to drought responses. 9-cis-epoxycarotenoid dioxygenase （NCED3） is thought to be a key enzyme in ABA biosynthesis. In this paper, we measured the ABA content increase under drought stress, and sequenced and compared the sequence of AtNCED3 among 22 Arabidopsis thaliana accessions. The results showed that the fold of ABA content increase under drought stress was highly variable among these accessions. High density single nucleotide polymorphism （SNP） and insertion/deletion （indel） were found in the AtNCED3 region, on average one SNP per 87.4 bp and one indel per 502 bp. Nucleotide diversity was significantly lower in the coding region than that in non-coding regions. The results of an association study with ANOVA analysis suggested that the 274th site （P←→S） and the 327th site （P←→R） amino acid variations might be the cause of ABA content increase of 163av accession under drought stress.

关键词： abscisic acid Arabidopsis thaliana association study drought stress NCED3 region nucleotide variation.

Modeling and Analysis for Supply Chain Using Stochastic Process Algebra

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Journal of Harbin Institute of Technology(New Series) 2014年第6期21卷 74-80页

作者： yong-Tao Huang Min Lv gang Wang Bing-Yin Ren hao-Yun Zhang School of Mechatronics Engineering Harbin Institute of Technology Henan Tongli Cement Co. Ltd.

In order to improve the influence of the uncertain and dynamic of node enterprise behavior on the performance of supply chain,the method based on stochastic process algebra for description,analysis,validation and evaluation of supply chain business process model is ***,the description of the uncertainty of node enterprise behavior is given using the extended Unified Modeling Language sequence diagram,and mapping rule is defined from the extended Unified Modeling Language sequence diagram to stochastic process ***,on the basis of the acquired stochastic process algebra model,the supply chain business process model is verified with Mobility ***,according to the operational semantics of stochastic process algebra,the continuous-time Markov chain,isomorphic with stochastic process algebra model,is built; and the system performance evaluation of transient status and stable status is respectively conducted in accordance with Markov transfer relations and the current state of system,obtaining the predicted performance value and average performance index value for a specific period of *** simulation experiments show that the proposed method can accurately describe the stochastic behaviors of supply chain system and interactions among nodes,effectively verify the validity of the model,and objectively and exactly evaluate design of the supply chain.

关键词： supply chain stochastic process algebra business process performance evaluation Markov chain

Experimental Study of Air Layer Drag Reduction with Bottom Cavity for A Bulk Carrier Ship Model

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China Ocean Engineering 2019年第5期33卷 554-562页

作者： WU hao OU yong-peng Key Laboratory of High Performance Ship Technology (Wuhan University of Technology) Ministry of Education Wuhan 430063 China School of Transportation Wuhan University of Technology Wuhan 430063 China College of Naval Architecture and Ocean Engineering Naval University of Engineering Wuhan 430033 China

Air lubrication by means of a bottom cavity is a promising method for ship drag reduction. The characteristics of the bottom cavity are sensitive to the flow field around the ship hull and the effect of drag reduction, especially the depth of the bottom cavity. In this study, a ship model experiment of a bulk carrier is conducted in a towing tank using the method of air layer drag reduction (ALDR) with different bottom cavity depths. The shape of the air layer is observed, and the changes in resistance are measured. The model experiments produce results of approximately 20% for the total drag reduction at the ship design speed for a 25-mm cavity continuously supplied with air at Cq = 0.224 in calm water, and the air layer covers the whole cavity when the air flow rate is suitable. In a regular head wave, the air layer is easily broken and reduces the drag reduction rate in short waves, particularly when λ/Lw1 is close to one;however, it still has a good drag reduction effect in the long waves.

关键词： air layer drag reduction bulk carrier model test depth of cavity air layer shape

新发皮质下小梗死患者危险因素和影像学特征及预后的分析

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中华老年心脑血管病杂志 2017年第6期19卷 608-610页

作者：郝咏刚范慧敏杨淑娜李悦秦伟杨磊袁俊亮胡文立首都医科大学附属北京朝阳医院神经内科 100020

目的分析新发皮质下小梗死患者的危险因素和影像学特征及预后。方法选取2011年1月~2015年5月在首都医科大学附属北京朝阳医院神经内科住院的脑小血管病患者1011例,对其中年龄85岁25例(老年组),共55例新发皮质下小梗死患者进行回顾性研究... 详细信息

目的分析新发皮质下小梗死患者的危险因素和影像学特征及预后。方法选取2011年1月~2015年5月在首都医科大学附属北京朝阳医院神经内科住院的脑小血管病患者1011例,对其中年龄85岁25例(老年组),共55例新发皮质下小梗死患者进行回顾性研究,对比2组入院时病史、化验结果、影像学特征及预后。结果老年组TG、尿素、肌酐、脑白质疏松程度(总体,脑室旁,深部)、入院时美国国立卫生研究院卒中量表评分和生活能力改善比例明显高于青年组;老年组吸烟、同型半胱氨酸、舒张压、入院时Barthel指数明显低于青年组[36.0%vs 80.0%,P=0.000;(20.00±2.83)mmol/L vs(30.60±1.83)mmol/L,P=0.001;(84.42±4.24)mm Hg vs(93.47±5.15)mm Hg,P=0.001,1mm Hg=0.133kPa;(50.79±10.88)分vs(82.67±10.69)分,P=0.006]。结论新发皮质下小梗死青年与老年患者的危险因素、影像学特征及预后均有差异。

关键词：新皮质脑梗死磁共振成像,弥散危险因素

Research Progress of Parallel Control and Management

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IEEE/CAA Journal of Automatica Sinica 2020年第2期7卷 355-367页

作者： gang Xiong Xisong Dong hao Lu Dayong Shen State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China School of Computer Science and Technology Beijing Institute of TechnologyBeijing 100081China College of Systems Engineering National University of Defense TechnologyChangsha 410073China

Based on ACP(artificial systems,computational experiments,and parallel execution)methodology,parallel control and management has become a popularly systematic and complete solution for the control and management of complex *** paper focuses on summarizing comprehensive review of the research literature of parallel control and management achieved in the recent years including the theoretical framework,core technologies,and the application *** future research,application directions,and suggestions are also discussed.

关键词： ACP methodology artificial systems computational experiments parallel control parallel management parallel systems

Enzymatic nitrous oxide emissions from wastewater treatment

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Frontiers of Environmental Science & Engineering 2018年第1期12卷 113-124页

作者： gang Guo Yayi Wang Tianwei hao Di Wu Guang-hao Chen Department of Civil ＆ Environmental Engineering The Hong Kong University of Science and Technology Hong Kong 999077 China State Key Laboratory of Pollution Control and Resources Reuse College of Environmental Science and Engineering Tongji University Shanghai 200092 China Institute for Advanced Study The Hong Kong University of Science and Technology Hong Kong 999077 China Hong Kong Branch of the Chinese National Engineering Research Center for Control ＆ Treatment of Heavy Metal Pollution The Hong Kong University of Science and Technology Hong Kong 999077 China Wastewater Treatment Laboratory FYT Graduate School The Hong Kong University of Science and Technology Guangzhou 511458 China

Nitrous oxide （N20）, a potent greenhouse gas, is emitted during nitrogen rernoval in wastewater treatment, significantly contributing to greenhouse effect. Nitrogen removal generally involves nitrification and denitrification catalyzed by specific enzymes. N20 production and consumption vary considerably in response to specific enzyme-catalyzed nitrogen imbalances, but the mechanisms are not yet completely understood. Studying the regulation of related enzymes＂ activity is essential to minimize N20 emissions during wastewater treatment. This paper aims to review the poorly understood related enzymes that most commonly involved in producing and consuming N20 in terms of their nature, structure and catalytic mechanisms. The pathways of N20 emission during wastewater treatment are briefly introduced. The key environmental factors influencing N20 emission through regulatory enzymes are summarized and the enzyme-based mechanisms are revealed. Several enzyme- based techniques for mitigating N20 emissions directly or indirectly are proposed. Finally, areas for further research on N20 release during wastewater treatment are discussed.

关键词： Nitrous oxideMitigationEnzyme catalysisNitrogen removalWastewater treatment

Topography of the 660-km discontinuity within the Izu-Bonin subduction zone and evidence of slab penetration near the Bonin Super Deep Earthquake(~680 km)

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Earthquake Science 2023年第6期36卷 458-476页

作者： gang hao Graduate School of Science Faculty of ScienceKyushu UniversityMotookaNishi-kuFukuokaJapan

The Izu-Bonin subduction zone in the Northwest Pacific is an ideal location for understanding mantle dynamics such as cold lithosphere subduction. The slab produces a lateral thermal anomaly, inducing local topographic changes at the boundary of a post-spinel phase transformation, considered to be the origin of the ‘660-km discontinuity.’ In this study, the short-period(1–2 Hz) S-to-P conversion phase S660P was used to obtain the fine-scale structure of the discontinuity. More than 100 earthquakes that occurred from the 1980s to the 2020s and were recorded by high-quality seismic arrays in the United States and Europe were analyzed. A discontinuity in the ambient mantle with an average depth of ~670 km was found beneath the 300–400-km event zone in the northern Bonin region near 33°N. Meanwhile, the ‘660-km discontinuity’ has been pushed upward, away from the slab, possibly because of a hot upwelling mantle plume. In the central part of the subduction zone, the 660-km discontinuity is depressed to an average depth of(690 ± 5) km within the slab at approximately 150 km below the coldest slab core, indicating a(300 ± 100) ℃ cold anomaly estimated using a post-spinel transformation Clapeyron slope of(-2.0 ± 1.0) MPa/K. In southern Bonin near 28°N, the discontinuity was found to be further depressed at an average depth of(695 ± 5) km below the deepest event and with a focal depth of ~550 km. The discontinuity is located where the slab bends abruptly to become sub-horizontal toward the west-southwest. Near the zone of the isolated Bonin Super Deep Earthquake, which occurred at ~680 km on May 30,2015, the discontinuity is depressed to ~700 km, suggesting a near-vertical penetrating slab and an S-to-P conversion in the coldest slab core, where a large low-temperature anomaly should exist.

关键词： Izu-Bonin subduction zone discontinuity post-spinel transformation S-to-P wave conversion vertical subduction cold slab