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Hydrodynamic characteristics of Wujiangdu Reservoir during the dry season-a case study of a canyon reservoir

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Acta Geochimica 2017年第3期36卷 506-510页

作者： Haitao Zhang Baoli Wang qiong han Jie Shi Xiaolong Qiu Tiejun Wang Institute of Surface-Earth System Science Tianjin University Tianjin 300072 China State Key Laboratory of Environmental Geochemistry Institute of Geochemistry Chinese Academy of SciencesGuiyang 550002 China University of Chinese Academy of Sciences 100049 BeijingChina

With the development of hydropower in the karst area of Southwest China, a series of cascade canyon reservoirs have been formed through the construction of dams. Given that hydrodynamic conditions in canyon reservoirs play a pivotal role in controlling the spatiotemporal distribution of physical and chemical properties of the stored water, hydrodynamic characteristics are of great importance in understanding biogeochemical cycles in those reservoirs. To further this understanding, a field campaign was conducted in the Wujiangdu Reservoir of Guizhou Province. It was found that from the reservoir inlet to the front of the dam, velocity(v) was negativelycorrelated and had a logarithmic relationship with distance along the ship track(s) under dry-season flow conditions[v =-0.104 ln(s) + 0.4756]. Analysis showed that dryseason flow velocity had no significant correlation with water temperature, p H, or dissolved oxygen(DO). However, when velocity decreased to 0.061 m/s, water depth increased abruptly. In addition, DO displayed a sudden drop and the trend in p H changed from increasing to decreasing, while water temperature showed an opposite trend, indicating the existence of a transition zone from the river to the reservoir.

关键词： Canyon reservoir Hydrodynamic characteristics A transition zone Wujiang River

Lipid-lowering effects of oleanolic acid in hyperlipidemic patients

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Chinese Journal of Natural Medicines 2018年第5期16卷 339-346页

作者： LUO han-qiong SHEN Jie CHEN Cai-Ping MA Xiao LIN Chao OUYANG qiong XUAN Chun-Xiao LIU Jine SUN Hong-Bin LIU Jun Jiangsu Key Laboratory of Drug Screening and Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease China Pharmaceutical University First Affiliated Hospital Nanjing Medical University

Oleanolic acid(OA) is a pentacyclic triterpenoid compound extracted from olea europaeal, a traditional Chinese medicine herb. OA has been used in the clinic as a hepatoprotective medicine in China since 1970 s. In our previous study, we observed that OA could ameliorate hyperlipidemia in animal models. In the present study, we conducted a small-scale clinical trial to evaluate the hypolipidemia effect of OA in hyperlipidemic patients. Hyperlipidemic patients were administrated with OA for four weeks(4 tablets once, three times a day). The blood samples of the patients were collected before and after OA treatment. The biological parameters were measured. Furthermore, three patients' blood samples were studied with DNA microarray. After OA administration, the TC, TG, and HDLC levels in serum decreased significantly. DNA microarray analysis results showed that the expressions of 21 m RNAs were significantly changed after OA treatment. Bioinformatics analysis showed 17 m RNAs were up-regulated and 4 m RNAs were down-regulated significantly after OA treatment. Five m RNAs(CACNA1 B, FCN, STEAP3, AMPH, and NR6 A1) were selected to validate the expression levels by q RT-PCR. Therefore, OA administration differentially regulated the expression of genes involved in lipid metabolism. The data showed a clinical evidence that OA could improve hyperlipidemia and also unveiled a new insight into the molecular mechanisms underlying the pharmacological effect of OA on hyperlipidemia.

关键词： Oleanolic acid Hyperlipidemia DNA microarray Pathway analysis Clinic

Rolling Iterative Prediction for Correlated Multivariate Time Series

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国际计算机前沿大会会议论文集 2023年第1期 433-452页

作者： Peng Liu qiong han Xiao Yang College of Computer Science and Technology Harbin Engineering UniversityHarbin 150001China

Correlated multivariate time series prediction is an effective tool for discovering the chang rules of temporal data,but it is challenging toﬁnd these ***,deep learning methods have made it possible to predict high-dimensional and complex multivariate time series ***,these methods cannot capture or predict potential mutation signals of time series,leading to a lag in data prediction trends and large ***,it is difﬁcult to capture dependencies of the data,especially when the data is sparse and the time intervals are *** this paper,we proposed a prediction approach that leverages both propagation dynamics and deep learning,called Rolling Iterative Prediction(RIP).In RIP method,the Time-Delay Moving Average(TDMA)is used to carry out maximum likelihood reduction on the raw data,and the propagation dynamics model is applied to obtain the potential propagation parameters data,and dynamic properties of the correlated multivariate time series are clearly *** Short-Term Memory(LSTM)is applied to capture the time dependencies of data,and the medium and long-term Rolling Iterative Prediction method is established by alternately estimating parameters and predicting time *** are performed on the data of the Corona Virus Disease 2019(COVID-19)in China,France,and South *** results show that the real distribution of the epidemic data is well restored,the prediction accuracy is better than baseline methods.

关键词： Time Series Prediction Correlated Multivariate Time Series Trend Prediction of Infectious Disease Rolling Circulation

The Multisource Time Series Data Granularity Conversion Method

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国际计算机前沿大会会议论文集 2023年第1期 182-191页

作者： Chongyang Leng qiong han Dan Lu Harbin Engineering University HarbinChina

Granular information has emerged as a potent tool for data represen-tation and processing across various ***,existing time series data granulation techniques often overlook the inﬂuence of external *** this study,a multisource time series data granularity conversion model is proposed that achieves granularity conversion effectively while maintaining result consis-tency and *** model incorporates the impact of external source data using a multivariate linear regression model,and the entropy weighting method is employed to allocate weights andﬁnalize the granularity *** experimental analysis using Beijing’s 2022 air quality dataset,our proposed method outperforms traditional information granulation approaches,providing valuable decision-making insights for industrial system optimization and research.

关键词： Time series data Granular conversion Fuzzy c-means clustering Multiple linear regression

The apoplexy the head electricity needle is cured studies clinically

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The apoplexy the head electricity needle is cured studies cl...

Two New Schiff Bases Based on 5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde: Syntheses, Crystal Structures and Properties

全国针灸临床适宜技术推广研讨会暨甘肃省针灸学会2013年学术年会

作者： Fu Wei han qiong Yang Dexiang Gansu Province Qing Yang county city celebration city county branch elder uncle middle hospital

That the head electricity needle cures apoplexy 158 examples clinical observation purpose is the method curing the mechanism being hit by apoplexy falling ill,seeking simpler, just,prove effective,cheap treating thereby for discussing the head electricity needle further. Method:Area gives first place to *** scalp acupuncture,consult the Jin San needle mainly, cure the apoplexy patient combining with the electricity needle 158 examples,treat having efficiency for 96.2%.155 examples adopt a body acupuncture treat,have efficiency 81.29%,81.29%,P han explaining that the effect curing an apoplexy the head electricity needle group is obvious cures an apoplexy,and have fetching a cave going to the lavatory fewer but better,pragmatic,the curative effect is definite,fall ill to the apoplexy initial stage urge being awake reaching sequela having obvious effect phase equally.

关键词： The electricity needle cures apoplexy one of the disease studying being hit by apoplexy falling ill is to endanger healthy 4-big of human being clinically morbidity lives in the first place in our country.Whose death rate height sequela are many bring gigantic burden to gigantic burden home life and society the disease studying and discussing an apoplexy has cured the problem being to have clinical medicine value in the homeland very much we from October 2002 to October 2006 have adopt 158 examples curing an apoplexy the head electricity needle has got the satisfied effect report now as follows

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Chinese Journal of Structural Chemistry 2019年第3期38卷 408-415页

作者： SUN Feng-Mei han qiong JIANG Zheng-Jing ZHAO Pan-Xiang WANG Jia RUI Jia-Yi XU Ji-Ming School of Chemistry and Chemical Engineering Huaiyin Normal University

Two new Schiff bases based on 5-chloro-3-methyl-1-phenyl-1 H-pyrazole-4-carbaldehyde, namely, N-((5-chloro-3-methyl-1-phenyl-1 H-pyrazol-4-yl)methylene)-4-morpholinoaniline(Ⅲa) and N-((5-chloro-3-methyl-1-phenyl-1 H-pyrazol-4-yl)methylene)-3-fluoro-4-morpholinoaniline(Ⅲb), were synthesized and characterized by IR, LC-MS, 1 H NMR and 13 C NMR spectroscopy. Meanwhile, the three-dimensional configurations of the two title compounds were further characterized by single-crystal X-ray diffraction analyses. Both the compounds are thermodynamically stable trans-isomers. Moreover, the fluorescence properties and antioxidant activities against DPPH of the two target compounds have been investigated, and the results showed that the title compounds both have fluorescence performance and certain antioxidant activities against DPPH radical.

关键词： Schiff base 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde synthesis crystal structure property

基于ArcGISEngine的土地登记发证综合查询系统研究

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测绘通报 2006年第10期 62-64页

作者：韩琼武汉大学资源与环境科学学院

在简要介绍土地登记业务的基础上,进行信息化需求及功能设计需求分析,使用PowerDesigner数据库建模工具,基于SQLServer数据库管理系统进行数据的设计和创建。系统实现采用数据字典技术、动态数据模型技术和数据更新技术,基于ArcEngine... 详细信息

在简要介绍土地登记业务的基础上,进行信息化需求及功能设计需求分析,使用PowerDesigner数据库建模工具,基于SQLServer数据库管理系统进行数据的设计和创建。系统实现采用数据字典技术、动态数据模型技术和数据更新技术,基于ArcEngine平台实现土地登记公开查询系统。

关键词：土地登记动态数据模型 RDBMS ADO 数据字典

Content-based facial image authentication via statistic features

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通讯和计算机（中英文版） 2009年第2期6卷 16-20页

作者： han Qi LI qiong NIU Xia-mu School of Computer Science and Technology Harbin Institute of Technology Harbin l 50001 China

Comparison of three methods for isolation of nucleic acids from membranate inner ear tissue of rats

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Chinese Medical Journal 2006年第12期119卷 986-990页

作者： KONG Wei-jia WANG Ying WANG qiong han Yue-chen HU Yu-juan Department of Otorhinolaryngology Union Hospital of TongjiMedicial College Huazhong University of Science and TechnologyWuhan 430022 China

Background Mitochondrial DNA mutations have been found in sensorineural deafness. The aim of this study was to compare three methods for extraction of nucleic acid from membranate inner ear tissue of rats. Methods Alkaline denaturation, a conventional phenol-chloroform method and Trizol reagent were respectively used to extract the slight nucleic acid from membranate inner ear tissue of rats. We assessed the amount and quality of nucleic acid using a UV-spectrometer and polymerase chain reaction （PCR）. Results The yield and purity （OD260/OD280） of DNA from inner ear tissue using the phenol-chloroform method was the highest of the three methods. Mitochondrial DNA （mtDNA） fragment can be amplified by PCR from nucleic acid prepared by all methods, while no nuclear DNA （nDNA） fragment can be amplified by method of alkaline denaturation. Both nuclear and mitochondrial genes could be amplified by reverse transcriptional PCR from the RNA prepared by Trizol reagent. Conclusion Adequate amount and high-quality of mtDNA, nDNA and RNA were obtained from unilateral membranate inner ear tissue of rats. Method of alkaline denaturation could be chosen when mtDNA without nDNA was needed, while phenol-chloroform method was suitable for extracting total DNA （including nDNA and mtDNA）： method with Trizol reauent was suitable for extractinu total RNA and total DNA.

关键词： mitochondnal DNA nuclear DNA RNA polymerase chain reaction