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Effects of different courses of moxibustion treatment on intestinal flora and inflammation of a rat model of knee osteoarthritis

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Journal of Integrative Medicine 2022年第2期20卷 173-181页

作者： Ye-juan jia Tian-yu Li Peng han yu Chen Li-jia Pan Chun-sheng jia School of Acupuncture Moxibustion and TuinaHebei University of Chinese MedicineShijiazhuang 050200Hebei ProvinceChina

Objective:This study was done to determine the effects of different courses of moxibustion on a rat knee osteoarthritis(KOA)model,and explore the dose–effect relationship of moxibustion on KOA from the perspectives of intestinal flora and inflammatory ***:Wistar rats were randomly divided into five groups:normal,model,moxibustion for 2 weeks,moxibustion for 4 weeks and moxibustion for 6 weeks groups(n=5 each group).A KOA rat model was induced by monosodium iodoacetate,and moxibustion intervention was performed at the acupoints“Dubi”(ST35)and“Zusanli”(ST36),once every other *** changes in the cartilage of rat knee joints were assessed after intervention,and fecal samples were subjected to 16 S r RNA high-throughput sequencing for microbial diversity ***:Damage to the knee articular cartilage was obvious in the model group,which also had increased levels of pro-inflammatory factors,decreased levels of anti-inflammatory factors,and intestinal flora disorders with decreased *** degree of cartilage damage in the 4 and 6 weeks of moxibustion groups was significantly improved compared with the model *** 4 and 6 weeks of moxibustion groups also demonstrated reduced levels of interleukin-1βand tumor necrosis factor-a and increased levels of interleukin-10(P<0.05).Both the abundance and diversity of the intestinal flora were increased,approaching those of the normal *** of probiotics Eubacterium coprostanoligenes group and Ruminococcaceae UCG-014 increased,while that of the pathogenic bacteria Lachnospiraceae NK4 A136 group decreased(P<0.05).Although the abundance of Lachnospiraceae NK4 A136 group decreased in the 2 weeks of moxibustion group compared with the model group(P<0.05),there was no statistically significant difference in serum inflammatory factors,flora species diversity or degree of pathological damage compared with the model ***:Moxibustion treatment led to significant improvements in t

关键词： Knee osteoarthritis Different courses Moxibustion treatment Intestinal flora Inflammatory cytokines

Flow-Induced Vibration Fatigue Damage of A Pair of Flexible Cylinders in A Staggered Array

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China Ocean Engineering 2021年第6期35卷 878-890页

作者： XU Wan-hai LI yu-han jia Kun LAI jiang State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China Nuclear Power Institute of China Chengdu 610041China

Flow-induced vibration(FIV)of a group of long,flexible cylinders involves a complex interaction between fluid and *** a substantial number of studies have been devoted to assessing FIV response behaviours,fatigue damage features of staggered flexible cylinders are not fully ***,the wake-induced flutter constitutes an intricate hydrodynamic behaviour that frequently occurs when one cylinder is in the vicinity of another ***,existing studies on the fatigue damage caused by wake-induced flutter are incapable of achieving better *** paper,therefore,estimates the FIV fatigue damage of two staggered flexible cylinders with an aspect ratio of 350 and a mass ratio of 1.90 based on normal S−N curves according to Det Norske Veritas(DNV)*** staggered cases(cross-flow spacing ratios of 2.0,3.0,4.0,and 6.0 and in-line spacing ratios of 4.0,6.0,and 8.0)are discussed for comparison,and fatigue damage caused by wake-induced flutter is thoroughly *** damage results indicate that the variation of the cross-flow(CF)spacing ratio has a greater influence than that of the in-line(IL)spacing ratio on the CF fatigue damage of the upstream *** IL fatigue damages of the upstream cylinder are observed when reduced velocity V_(r)≥15.03 due to the wake flow patterns with different IL spacing ***,wake interference,especially wake-induced flutter,predominates the fatigue damage characteristics of the downstream *** V_(r)=8.77−11.27,wake-induced flutter enhances the IL fatigue damage of the downstream cylinder and slightly affects that of the upstream ***,wake-induced flutter causes considerable IL fatigue damage disparity between the two staggered cylinders by suppressing the IL fatigue damage of the upstream cylinder when V_(r)≥20.04.

关键词： flow-induced vibration fatigue damage flexible cylinder staggered arrangement wake-induced flutter

Cerebral fat embolism following autologous fat injection in facial reconstruction:A case report

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World Journal of Clinical Cases 2025年第2期13卷 50-58页

作者： Xiu-Ying Chen Fa Shen Chang Cheng yu-han Wang Wen-Chao Cheng De-Zhi yuan Wen Huang Department of Neurology Chongqing Emergency Medical CenterChongqing University Central HospitalChongqing 400000China Department of Neurology Xinqiao HospitalThe Army Medical University(Third Military Medical University)Chongqing 400000China

BACKGROUND Autologous fat injection in facial reconstruction is a common cosmetic *** cerebral fat embolism(CFE)as a complication is rare,it carries serious health *** SUMMARY We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling *** the surgery,the patient experienced symptoms including headache,nausea,vomiting,and difficulty breathing,which was followed by neurological symptoms such as slurred speech and left-sided *** physical examination and auxiliary investigations,including blood tests,head and neck computed tomography angiography,and cranial magnetic resonance diffusion-weighted imaging,were performed upon *** clinical diagnosis was acute cerebral embolism following facial fat filling *** included measures to improve cerebral circulation,dehydration for intracranial pressure reduction,nutritional support,and rehabilitation therapy for left limb *** patient showed a significant improvement in symptoms after 2 weeks of *** recovered left limb muscle strength to grade 5,had clear speech,and experienced complete relief of *** Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial *** prevent these complications,plastic surgeons should enhance their professional knowledge and skills.

关键词： Cerebral fat embolism Mechanical thrombectomy Thrombolysis Steroid therapy Symptomatic treatment Case report

四川省美沙酮维持治疗患者脱失现状及其影响因素

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现代预防医学 2019年第23期46卷 4363-4367页

作者：董佩杰韩佳禹杨淑娟余彬杨诗凡龚毅周英廖蕊唐程梦四川大学华西公共卫生学院/四川大学华西第四医院四川省疾病预防控制中心成都市武侯区第二人民医院

目的了解四川省美沙酮维持治疗患者的脱失现状,分析患者脱失的影响因素,为降低美沙酮维持治疗的脱失率提供理论依据。方法多阶段整群随机法,通过面对面问卷调查,对四川省5家美沙酮美沙酮维持治疗门诊点的581名海洛因成瘾者的脱失情况进... 详细信息

目的了解四川省美沙酮维持治疗患者的脱失现状,分析患者脱失的影响因素,为降低美沙酮维持治疗的脱失率提供理论依据。方法多阶段整群随机法,通过面对面问卷调查,对四川省5家美沙酮美沙酮维持治疗门诊点的581名海洛因成瘾者的脱失情况进行调查,使用卡方检验和logistic回归分析,探究美沙酮患者脱失的影响因素。结果 logistic回归分析发现,调查对象过去6个月的脱失情况与其对美沙酮维持治疗的认知有关(P50 ml的患者不易发生脱失(OR=0.568,95%CI:0.333～0.969);与家人现阶段关系非常好或较好的患者不易发生脱失(OR=0.509,95%CI:0.264～0.982)。偷吸海洛因的患者容易发生服药脱失(OR=2.542,95%CI=1.879-4.299)。结论 MMT门诊应对美沙酮患者进行适当的健康教育,普及正确的美沙酮维持治疗知识,帮助恢复其家庭及社会功能、克服毒瘾,减少患者的脱失。

关键词：美沙酮脱失影响因素

Climatic impacts induced by winter wheat irrigation over North China simulated by the nonhydrostatic RegCM4.7

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Advances in Climate Change Research 2024年第2期15卷 197-210页

作者： jia WU Zhen-yu han Xue-Jie GAO Zheng-jia LIU National Climate Centre China Meteorological AdministrationBeijing 100081China Key Laboratory for Climate Studies China Meteorological AdministrationBeijing 100081China Climate Change Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjing 210044China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China

Quantification of the impact of winter wheat irrigation on the climate and the occurrence of extreme climatic events over North China is crucial for regional adaptation *** related studies mainly focused on the impact on surface processes;however,few focused on the effects of extreme events using high-resolution nonhydrostatic regional climate ***,the 9-km-resolution nonhydrostatic RegCM4.7 was coupled with a crop irrigation scheme and an updated winter wheat irrigation dataset to better simulate irrigation *** experiments were conducted with and without winter wheat irrigation to isolate the effects of *** showed that irrigation simulation reduces the model biases in temperature,precipitation,latent heat flux,soil moisture,sensitive heat flux,and top-layer soil ***,it also reduces the bias and increases the correlation with observations obtained in irrigated areas,especially in summer,indicating better representation of irrigation *** wheat irrigation tends to cause substantial cooling of the local surface maximum,minimum,and mean air temperatures(by-1.68,-0.34,and-0.79℃,respectively)over irrigated areas of North China,with the largest changes observed in relation to maximum ***,precipitation is found to increase during spring and summer,which is strongly related to water vapor transport in the lower levels of the *** analyses indicated that the number of annual mean hot days decrease(-13.9 d),whereas the number of both comfort days(+10.2 d)and rainy days(days with total precipitation greater than 1 mm:+6.6 d)increase over irrigated areas,demonstrating beneficial feedback to human perception and ***,although the heat wave risk increases(number of annual mean heat wave days:+5.8 d),the impact is limited to small areas within irrigated ***,no notable change was found in terms of heavy rainfall events and precipitation intensity

关键词： Nonhydrostatic regional climate model Irrigation effect Extreme events North China

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热区葡萄育种研究进展

南方农业学报 2024年第8期55卷 2374-2385页

作者：王博郭荣荣成果韩佳宇林玲何建军白扬谢蜀豫王举兵白先进广西大学农学院广西南宁530004 广西农业科学院葡萄与葡萄酒研究所广西南宁530007 广西特色作物研究院/广西桂北特色经济作物种质创新与利用实验室广西桂林541004 广西真诚农业有限公司广西南宁530105 广西水果技术指导站广西南宁530022

葡萄是温带果树,葡萄生产及新品种培育主要分布在气候干燥凉爽的温带地区。随着避雨、破眠、一年两收等葡萄栽培新技术的推广,热区葡萄由于早熟、错季经济效益明显,近年发展迅猛,该区已成为我国特色优势栽培区。葡萄新品种对葡萄产业的... 详细信息

葡萄是温带果树,葡萄生产及新品种培育主要分布在气候干燥凉爽的温带地区。随着避雨、破眠、一年两收等葡萄栽培新技术的推广,热区葡萄由于早熟、错季经济效益明显,近年发展迅猛,该区已成为我国特色优势栽培区。葡萄新品种对葡萄产业的快速发展起着重要推动作用。文章结合国内外研究进展提出热区葡萄育种的必要性,概述当前热区葡萄产业现状、主栽葡萄品种及存在问题:由于我国热区葡萄育种工作起步较晚,目前热区主栽葡萄品种仍为温带地区育成,均不耐湿热,存在着色障碍、品质下降、抗性差、易感多种病虫害、需冷量较高、发芽不整齐和易发生日灼等“水土不服”问题。文章分析了热区育种的优势:热区积温高,实生苗生长量大,结果早,育种效率高;热区分布的野生耐热葡萄资源丰富,是培育耐热抗性强新品种的宝贵材料;热区逆境条件可为耐热抗病葡萄新品种的选育提供天然的筛选环境。总结湿热地区葡萄育种研究进展,包括葡萄栽培技术基础、育种机构和专业技术人才队伍情况。阐述广西葡萄种质资源引进与评价的基础,介绍巴西热区葡萄遗传育种研究计划的代表性新品种及广西热区葡萄选育品种的登记及保护情况,并提出我国热区葡萄育种下一步工作计划。在高热高湿、降雨多、日照时数少、冬季低温时数少的热区逆境气候环境下选育早熟优质、抗性强、易栽培和耐储运葡萄新品种是热区葡萄产业健康高质量可持续发展的保障,对提升热区葡萄新质生产力具有重要意义。

关键词：热区逆境葡萄育种优势进展

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大学生防艾生活技能评估量表的开发研究

现代预防医学 2018年第23期45卷 4327-4330页

作者：姚永娜翟雯雯李超余彬韩佳禹赵庆革杨文婷苗泓丽张建新四川大学华西公共卫生学院四川大学艾滋病研究中心绵阳师范学院双流区妇幼保健院成都纺织高等专科学校四川护理职业学院四川省性病艾滋病防治协会

目的开发《大学生防艾生活技能评估量表》,对量表的信效度进行评价。方法以成都市两所高校的2843名大学生为研究对象,采用头脑风暴、专家咨询的定性方法和区分度分析、克朗巴赫α系数法和因子分析等定量方法,按照标准化量表编制程序进... 详细信息

目的开发《大学生防艾生活技能评估量表》,对量表的信效度进行评价。方法以成都市两所高校的2843名大学生为研究对象,采用头脑风暴、专家咨询的定性方法和区分度分析、克朗巴赫α系数法和因子分析等定量方法,按照标准化量表编制程序进行量表编制。结果编制的大学生防艾生活能力量表含毒品严重性感知、艾滋病严重性感知、易感性感知、寻求帮助能力、协商能力、拒绝能力、安全套使用倾向、知觉行为控制8个维度,共计30个条目。量表的Cronbach’sα系数为0. 749,重测信度系数为0. 804,专家积极系数为100%,专家权威系数为0. 829,结构效度的模型评价结果 2/df为4. 071,近似误差均方根(RMSEA)为0. 057,模型拟合合理。结论该量表能较全面的反映大学生艾滋病防治的生活技能,具有较好的信度和合适的效度,可作为测量大学生防艾生活技能工具。

关键词：艾滋病生活能力量表效度信度

四川省美沙酮维持治疗患者偷吸海洛因现状及其与家庭和社会功能的相关性研究

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现代预防医学 2019年第17期46卷 3087-3090+3100页

作者：韩佳禹杨淑娟余彬董佩杰杨诗凡龚毅周英杨超廖蕊唐程梦四川大学华西公共卫生学院/四川大学华西第四医院四川省疾病预防控制中心成都市武侯区第二人民医院西南医科大学公共卫生学院流行病与统计教研室

目的探讨家庭和社会功能因素对美沙酮维持治疗患者偷吸行为的影响,为制定相应的干预对策提供依据。方法采用分层整群抽样方法抽取四川省5个美沙酮维持治疗门诊所有接受治疗的患者为对象,采用问卷调查,分析患者的基本情况、家庭和社会功... 详细信息

目的探讨家庭和社会功能因素对美沙酮维持治疗患者偷吸行为的影响,为制定相应的干预对策提供依据。方法采用分层整群抽样方法抽取四川省5个美沙酮维持治疗门诊所有接受治疗的患者为对象,采用问卷调查,分析患者的基本情况、家庭和社会功能情况对其偷吸行为的影响。结果在纳入的581名患者中,30.98%的患者在治疗过程中存在偷吸行为。多因素logistic回归分析表明,偷吸的影响因素有:海洛因吸毒年限越长("10～20年"与"20年"与"<10年"相比,OR=2.452)、使用过除海洛因以外的其他毒品(OR=2.078)、家庭关系差(OR=1.620)、家人提供的精神/经济上的支持少(OR=2.230)、接受美沙酮治疗后患者婚姻状况发生负向变化(OR=1.831)、因经济困难而偷抢骗等行为无变化或变多(OR=2.413)、感觉社会不接纳自己(OR=1.665)。结论家庭和社会功能越差者越容易发生偷吸行为,美沙酮门诊除提供美沙酮维持治疗服务外,还应该积极采取家庭及社会干预措施以减少偷吸行为,提高患者的依从性。

关键词：美沙酮维持治疗偷吸影响因素家庭功能社会功能

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桂南一年两收栽培夏黑葡萄花芽分化进程调控

南方农业学报 2017年第1期48卷 57-65页

作者：林玲曹慕明郭荣荣谢蜀豫韩佳宇盘丰平陈国品王世平白先进王博广西大学农学院南宁530004 广西农业科学院葡萄与葡萄酒研究所南宁530007 广西作物遗传改良生物技术重点开放实验室南宁530007 上海交通大学农业与生物学院上海200240 广西农业科学院南宁530007

【目的】了解和掌握不同调控措施下桂南夏黑葡萄新梢冬芽花芽分化的关键时期,为其一年两收栽培二次果花芽分化调控提供参考依据。【方法】以8年生夏黑葡萄为试材,于新梢5~7片叶时开始每周采集第6节位芽,通过制作石蜡切片,探讨不同夏季... 详细信息

【目的】了解和掌握不同调控措施下桂南夏黑葡萄新梢冬芽花芽分化的关键时期,为其一年两收栽培二次果花芽分化调控提供参考依据。【方法】以8年生夏黑葡萄为试材,于新梢5~7片叶时开始每周采集第6节位芽,通过制作石蜡切片,探讨不同夏季修剪强度(花上2片叶摘心、花上4片叶摘心和花上6片叶摘心)和乙烯利喷施浓度(200、400和800 mg/L)对桂南一年两收栽培夏黑葡萄新梢花芽分化进程及成花率的影响。【结果】不同夏季修剪强度处理的夏黑葡萄新梢冬芽从花芽分化开始(3月29日)到稳定形成花穗(4月27日~5月4日)历时29~37 d,比对照(不摘心,不喷施乙烯利)植株缩短14~22 d,其花芽分化关键时期在4月13日(盛花期)前后。不同夏季修剪强度处理下夏黑葡萄新梢第6节位花芽分化集中、花芽分化进程历时短、成花率(53.3%~73.3%)相对较高。不同乙烯利喷施浓度处理下夏黑葡萄新梢第6节位花芽分化各时期出现不集中,花芽分化进程历时长(52 d),成花率(33.3%~40.0%)较对照低。【结论】不同夏季修剪强度均可促进桂南一年两收栽培夏黑葡萄新梢花芽分化进程,其中花上6片叶摘心是促进夏黑葡萄新梢第6节位花芽分化集中、花芽分化进程时间缩短的一项重要措施。

关键词：夏黑葡萄花芽分化调控措施一年两收栽培成花率