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Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04

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International Journal of Ophthalmology(English edition) 2018年第4期11卷 553-558页

作者： Xi Chen Song-Man Li Yan-Wei Li Zi-hao han hao Liang Department of Ophthalmology the First Affiliated Hospital of Guangxi Medical University

AIM： To study the effect of senescence marker protein 30（SMP30） on the proliferation and apoptosis of human lens epithelial cell（HLEC） SRA01/***： SMP30 overexpression（OE） and knock down（KD） type cell lines were cultivated by using two groups regucalcin（RGN; SMP30） lentiviral vectors（LVRGN, LV-RGN-RNAi） and the respective negative control virus infect SRA01/04 cells. Western blot and real-time quantitative polymerase chain reaction（q-PCR） analysis were used to determine RGN overexpression and knock down efficiency. We use cell counting kit-8（CCK8） assay to measure cell viability and 5-bromodeoxyuridine（Brd U） assay to test cell proliferation. Cell cycle was measured by PI FACS assay and cell apoptosis was tested by Annexin V-APC assay through flow cytometry. We use Western blot to measure the content of caspase-3 in SRA01/***： We used PCR and Western blot techniques to determine the successful transfection of SMP30 OE and KD SRA01/04 cell lines. By CCK8, Brdu and PI FACS cell cycle assay, it was found that the SMP30 OE group promoted cell proliferation（P〈0.05） compared with the control group, and the KD group inhibited cell proliferation（P〈0.05）. The results of Annexin V-APC signal staining detection indicated that compared with respective control group, the cell apoptosis rate was higher in KD group（P〈0.05） but lower in OE group（P〈0.01）. The expression of caspase-3 was down-regulated in OE group through Western blot assay and up-regulated in KD group compared with respective control group. CONCLUSION： Proliferation of SRA01/04 was promoted by SMP30 OE and apoptosis was suppressed. Increasing the expression of SMP30 may protect HLEC SRA01/04 against apoptosis in cataract.

关键词： senescence marker protein 30 cell proliferation apoptosis human lens epithelial cell SRA01/04

Enhanced compactness and element distribution uniformity of Cu2ZnSnS4 thin film by increasing precursor S content

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Rare Metals 2020年第3期39卷 256-261页

作者： hao han Ji-Ning Wang Jing Mi Xiao-Peng Liu Li-Jun Jiang Department of Energy Material and Technology General Research Institute for Nonferrous MetalsBeijing100088China Beijing Engineering Research Center of Nonferrous Metal Products for New Energy Beijing100088China

Cu2ZnSnS4 thin films were prepared by cosputtering with Cu(or Cu2S),ZnS and SnS2 targets in this study.S amount in the precursor of Cu2ZnSnS4 thin film was verified by using Cu or Cu2S *** effect of S amount in the precursor on the microstructure and element distribution of Cu2ZnSnS4 thin film was *** was found that S content is sufficient in the precursor thin film using Cu2 S instead of Cu *** microstructure,composition homogeneity,and secondary phase formation of the Cu2ZnSnS4 thin film are seriously affected by S amount in the precursor thin ***,sufficient S can improve the crystallization and orientation of the precursor thin film and enhance the compactness as well as composition homogeneity of the Cu2ZnSnS4 thin film after ***,the secondary phase formation in Cu2ZnSnS4 thin film can be greatly inhibited by increasing S content in the precursor thin film.

关键词： Cu2ZnSnS4 Thin film S content Diffusion

Responding to the Paris Climate Agreement： global climate change mitigation efforts

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Frontiers in Energy 2018年第3期12卷 333-337页

作者： Yong GENG Tsuyoshi FUJITA Anthony CHIU hancheng DAI han hao School of Environmental Science and Engineering Shanghai Jiao Tong University Shanghai 200240 China China Institute for UrbanGovernance Shanghai Jiao Tong University Shanghai 200030 China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092 China National Institute for Environmental Studies Tsukuba Ibaraki 305-8506 Japan Gokongwei College of Engineering De La Salle University Manila1004 the Philippines College of Environmental Sciences and Engineering Peking UniversityBeijing 100871 China State Key Laboratory of Automotive Safety and Energy Tsinghua University Beijing 100084 China

Since the Paris Climate Agreement was adopted by consensus in December 2015, the global society has made various efforts to respond to this Agreement. The essential element of the Paris Climate Agreement is the so-called Nationally Determined Contributions （NDCs）, specifying the long-term greenhouse gas （GHG） reduc- tion targets beyond 2020. Unlike the different legal obligations of developed and developing countries specified in the precedent Kyoto Protocol, the NDCs under the Paris Climate Agreement apply equally to all countries. All the signed countries were asked to submit their Intended Nationally Determined Contributions （INDCs） before the 2015 Paris Climate Summit, which serve, unless otherwise provided, as the initial NDCs after the ratification of the Agreement.

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Small bowel racemose hemangioma complicated with obstruction and chronic anemia:A case report and review of literature

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World Journal of Gastroenterology 2020年第14期26卷 1674-1682页

作者： Ji-Xin Fu Ya-Nan Zou Zhi-hao han hao Yu Xin-Jian Wang Department of Gastrointestinal Surgery Weihai Central HospitalWeihai 264200Shandong ProvinceChina Department of Anesthesiology Weihai Central HospitalWeihai 264200Shandong ProvinceChina Department of Radiology Weihai Central HospitalWeihai 264200Shandong ProvinceChina

BACKGROUND Gastrointestinal hemangiomas are rare benign *** to the size of the affected vessels,hemangiomas are histologically classified into cavernous,capillary,or mixed-type tumors,with the cavernous type being the most common and racemose hemangiomas being very rare in the *** of uncertain origin and anemia are the main clinical manifestations,and other presentations are *** to the rarity of gastrointestinal hemangiomas and lack of specific manifestations and diagnostic methods,preoperative diagnoses are often delayed or *** SUMMARY We report a 5-year-old girl who presented with abdominal pain,nausea,and vomiting for a duration of 10 *** laboratory studies showed prominent *** tomography and contrast-enhanced computed tomography of the abdomen revealed a small bowel obstruction caused by a giant abdominal *** resection of the ileal lesions was performed through surgery,and the final pathology results revealed a diagnosis of racemose hemangioma complicated by a small bowel obstruction and simultaneous chronic *** The current report will increase the understanding of the diagnosis and treatment of gastrointestinal hemangiomas and provide a review of the related literature.

关键词： Gastrointestinal hemangioma Racemose hemangioma Small bowel obstruction Chronic anemia Computed tomography Case report

Carbon Price Forecasting Approach Based on Multi-Scale Decomposition and Transfer Learning

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Journal of Beijing Institute of Technology 2023年第2期32卷 242-255页

作者： Xiaolong Zhang Yadong Dou Jianbo Mao Wensheng Liu hao han Department of Energy Technology State Grid Zhejiang Electric Power Research InstituteHangzhou 310014China School of Marketing and Logistics Management Nanjing University of Finance and EconomicsNanjing 210023China Department of Production Technology E.Energy Technology Co.Ltd.Hangzhou 310012China

Accurate carbon price forecasting is essential to provide the guidance for production and *** research is mainly dependent on plenty of historical samples of carbon prices,which is impractical for the newly launched carbon market due to its short *** on the idea of transfer learning,this paper proposes a novel price forecasting model,which utilizes the correlation between the new and mature *** model is firstly pretrained on large data of mature market by gated recurrent unit algorithm,and then fine-tuned by the target market *** integral framework,including complexity decomposition method for data pre-processing,sample entropy for feature selection,and support vector regression for result post-processing,is *** the empirical analysis of new Chinese market,the root mean square error,mean absolute error,mean absolute percentage error,and determination coefficient of the model are 0.529,0.476,0.717%and 0.501 respectively,proving its validity.

关键词： carbon emission trading price forecasting transfer learning gated recurrent unit

Web-site Specificity:Internet as Medium in the Post-Internet Age

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Web-site Specificity:Internet as Medium in the Post-Internet...

作者： David hao han 中国美术学院

学位级别：硕士

网络艺术是一种多样性的实践活动,随着社会网络化程度的提高,它的文化相关性也在不断增强。“后网络”一词描述了我们当代的技术和社会状况,这种状况是通过社会日益融入网络文化而产生的,因此它并不区分在线与离线的世界。初期网络艺术... 详细信息

网络艺术是一种多样性的实践活动,随着社会网络化程度的提高,它的文化相关性也在不断增强。“后网络”一词描述了我们当代的技术和社会状况,这种状况是通过社会日益融入网络文化而产生的,因此它并不区分在线与离线的世界。初期网络艺术运动将网络定位为当时艺术表现的新空间,而后网络活动将社会的方方面面都置于网络文化的范畴内,因此所有的艺术活动都是同等的。虽然互联网包含许多可能性,但网站往往是视觉化程度最高的形式。因此,本文将重审网站–––这一滋养网络艺术的具体途径。通过对一些网络艺术家的深入探讨,重新聚焦网站作为创新媒介的独立个性,并将其置于后互联网时代的当代文化环境中,试图去理解在当代艺术的背景下,以互联网为导向的艺术实践的重要意义。

关键词：网络艺术网站 Web 2.0 社交媒体

Designed Synthesis of a Two-Dimensional Covalent Organic Framework with Three-Level Hierarchical Porosity

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Chinese Journal of Chemistry 2020年第12期38卷 1676-1680页

作者： Xiang-hao han Qiao-Yan Qi Zhi-Bei Zhou Xin Zhao Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules Center for Excellence in Molecular SynthesisShanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesChinese Academy of Sciences345 Lingling RoodShanghai 200032China

of main observation and conclusion Covalent organic frameworks(COFs)with hierarchical porosity have drawn considerable attention very recently due to their advantages over the COFs with uniform porosity in some ***,the design strategies for the construction of this type of COFs,namely heteropore COFs,are quite *** herein report a facile approach to constructing a two-dimensional COF which possesses three different kinds of *** structure is confirmed by powder X-ray diffraction and nitrogen sorption *** successful construction of the triple-pore COF represents a new method to access COFs with high hierarchical porosity.

关键词： porosity valent constructing

Effects of Different Operative Procedures on the Digestive and Nutritional Status of Patients Treated with a Gastrectomy for Gastric Cancer

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Chinese Journal of Clinical Oncology 2006年第3期3卷 216-222页

作者： han Liang Xishan hao Department of Gastrointestinal Surgical Oncology Tianjin Medical University Cancer Institute and Hospital Tianjin 300060 China.

Postgastrectomy syndromes evoked by the loss of several gastric functions after total or subtotal gastrectomy are very common. Dif- ferent kinds of reconstruction have been developed to overcome the problem. Patients with preservation of a duodenal passage and jejunal interposition with or without a pouch show a better quality of life and mini- mal symptoms postoperatively. A jejunal interposition with or without a pouch after proximal or distal subtotal gastrictomy seems to improve the nutritional condition and quality of life. The prognostic nutritional index (PNI), Visick score, Spitzer index and the European Organization for Re- search and Treatment of Cancer (EORTC) questionnaire (QLQ-C30) are available to evaluate the quality of life and nutritional status after gastrec- tomy.

关键词： gastrectomy digestion nutrition

The photometric system of the One-meter Telescope at Weihai Observatory of Shandong University

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Research in Astronomy and Astrophysics 2014年第6期14卷 719-732页

作者： Shao-Ming Hu Sheng-hao han Di-Fu Guo Jun-Ju Du Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment Institute of Space Sciences School of Space Science and Physics Shandong University

The one-meter telescope at Weihai Observatory （WHO） of Shandong University is an f/8 Cassegrain telescope. Three sets of filters are installed in a dual layer filterwheel that use Johnson-Cousins UBVRI, Sloan Digital Sky Survey u′g′r′i′z′ and Stomgren uvby. The photometric system and the CCD camera are introduced, followed by detailed analysis of their performances, and determination of the relevant parameters, including gain, readout noise, dark current and linearity of the CCD cam- era. In addition, the parameters describing the site＇s astro-climate, including typical seeing, statistics on the number of clear nights and average sky brightness, based on data gathered from Sep. 2007 to Aug. 2013, are systematically studied and reported in this work. Photometric calibrations were done using Landolt standard star obser- vations spanning eight nights, which yielded transformation coefficients, photometric precision and system throughput. The limiting magnitudes are simulated using the derived calibration parameters and classic observation conditions at WHO.

关键词： telescopes -- site testing --instrumentation: miscellaneous - tech-niques: photometric