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Methylation Profile Difference in Human High-Metastatic Large Cell Lung Cancer Cell lines with Different Metastatic Potential

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中国肺癌杂志 2009年第6期12卷 511-512页

作者： Hui LV Xiaoming QIU Ting WANG Yu FAN li MA Jun CHEN Sen WEI Zhigang li Hongyu liU haisu WAN Zhihao WU Qinghua ZHOU Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment Tianjin Lung Cancer Institute Tianjin Medical University Hospital Tianjin 300052 China

Background and Objective Invasion and metastasis is one malignant phenotype of lung cancer and cause the death of lung cancer patients. Present evidence has proved that invasion

关键词：肺癌癌细胞扩散化疗

The Difference of Gene Expression Prof ile in Human Large Cell Lung Cancer Cell lines with Different Metastatic Potential

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中国肺癌杂志 2009年第6期12卷 496-497页

作者： Xiaoming QIU Ting WANG Yu FAN li MA Jun CHEN Sen WEI Zhigang li Hongyu liU haisu WAN Zhihao WU Qinghua ZHOU Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment Tianjin Lung Cancer Institute Tianjin Medical University Hospital Tianjin 300052 China

Background and Objective Lung cancer is the most lethal malignangy that threatens human heath and lives nowadays in the world, and meanwhile is also the one with worst

关键词：肺癌扩散医学治疗

The Difference of the Copy Number Variation and Loss of Heterozygosity of Human Lung Large Cell Cancer Cell line with Different Metastatic Potential

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中国肺癌杂志 2009年第6期12卷 512-514页

作者： Bin HU Xiaoming QIU Ting WANG Yu FAN li MA Jun CHEN Sen WEI Zhigang li Hongyu liU haisu WAN Zhihao WU Qinghua ZHOU Tianjin Key Laboratory o fLung Cancer Metastasis and Tumor Microenvironment Tianjin Lung Cancer Institute Tianjin Medical University Hospital Tianjin 300052 China

Background and Objective It has been proven that copy number gain/or loss (copy number variation CNV) in uences gene expression and result in phenotypic variation by

关键词：肺癌癌细胞 CNV 治疗疗效

The Inhibiting Effects and It's Molecular Mecanisms of the Fungi of Huai Er's on Human Large Cell Lung Cancer Cell line L9981

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中国肺癌杂志 2009年第6期12卷 492-493页

作者： Yu FAN Zhilin SUN Yang QIN Wen ZHU li REN Jun CHEN Sen WEI Zhigang li Hongyu liU haisu WAN Zhihao WU Ke XU Qinghua ZHOU Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment Tianjin Lung Cancer Institute Tianjin Medical University Hospital Tianjin 300052 China The Key Laboratory of Lung Cancer Molecular Biology of Sichuan Province West China Hospital Sichuan Universit Chengdu 610041 China

Background and Objective Lung cancer, which threatens human’s health and life, is the malignant tumor with the most rapid increase of morbidity. Although recent years the basic

关键词：肺癌治疗疗效临床

Down-regulation and It's Molecular Biology of Nm-23H1 gene Transfection on Ras-to-MAPK Signal Transduction Pathway in Human High-metastatic Large Cell Lung Cancer Cell line L9981

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中国肺癌杂志 2009年第6期12卷 487-489页

作者： Yin li Jianjun QIN Yun WANG Jun CHEN Sen WEI Gang CHEN Zhigang li Hongyu liU haisu WAN Zhihao WU Ke XU QInghua ZHOU Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Micro- environment Tianjin Lung Cancer lnstitute Tianjin Medical University Hospital Tianjin 300052 China Department of Thoracic Surgery Cancer Hospital of Henan Province Zhengzhou Henan China Department of Thoracic Surgery West China Hospital Sichuan University Chengdu 610041 China

Backgroud and Objective Tumor metastasis is not only the malignant marker and characteristics of lung cancer, but also the key cause of failure to cure and lose their life of the patients

关键词：肺癌化疗疗效 MAPK

Changes of Gene Expression Prof iles and Biological Behaviors in Different Human Lung Cancer Cell lines by FLJ20420 Gene Silencing

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中国肺癌杂志 2009年第6期12卷 514-515页

作者： Baoxing liU Hui LV Xiaoming QIU Ting WANG Yu FAN li MA Jun CHEN Sen WEI Zhigang li Hongyu liU haisu WAN Zhihao WU Qinghua ZHOU Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironmentj Tianjin Lung Cancer Institute Tianjin Medical University Hospital Tianjin 300052 China

Background and Objective Lung cancer is the leading cause of cancer death in both men and women in both China and worldwide. Apoptosis is a highly regulated,

关键词：肺癌癌细胞扩散疗效

Transfection of Nm23-H1 Gene Inhibited the Metastatic Potential of Human High-metastatic Large Cell Lung Cancer L9981

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中国肺癌杂志 2009年第6期12卷 490-492页

作者： Haixia ZHENG Zhilin SUN Yang QIN Wen ZHU li REN Jun CHEN Sen WEI Zhigang li Hongyu liU haisu WAN Zhihao WU Ke XU Qinghua ZHOU Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Environment Tianjin Lung Cancer Institute Tianjin Medical University General Hospital Tianjin 300052 China Department of Medical Oncology Shenzhen Hospital Cancer Beijing University Shenzhen China The Key Laboratory of Lung Cancer Molecular Biology of Sichuan Province West China Hospital Sichuan University Chengdu 610041 China

Background and objective Invasion and metastasis is not only the malignant phenotypes of lung cancer but also the main cause of death. Elucidating the molecular mechanism of

关键词： Nm23-H1 肺癌临床治疗

Down-regulation and It's Molecular Biology of Nm-23H1 Gene Transfection on PKC Signal Path-way in Human High-metastatic Large Cell Lung Cancer Cell line L9981

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中国肺癌杂志 2009年第6期12卷 484-485页

作者： Qiang NIE Yun WANG Jun CHEN Seng WEI Gang CHEN Zhigang li Hongyu liU haisu WAN Zhihao WU Ke XU Qinghua ZHOU Tianjin Key Laboratory o fLung Cancer Metastasis and Tumor Microenvironment Tianjin Lung Cancer Institute Tianjin Medical University Hospital Tianjin 300052 China Department of Thoracic Surgery Lung Cancer Center People's Hospital of Guangdong Province Guangzhou China Department of Thoracic Surgery West China Hospital Sichuan University Chengdu Sichuan 610042 China

Backgroud and Objective At present, lung cancer has become the most frenquent malignant tumor in China and in the world which its mortality and morbidity is increasing fastest.

关键词：肺癌临床诊断化疗

The Regulating Mechanism of Nm23-H1 Gene for FAK Signal Pathway in Human Lung Cancer Cell line L9981

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中国肺癌杂志 2009年第6期12卷 489-490页

作者： Dejun KONG Zhilin SUN Yang QIN Wen ZHU li REN Jun CHEN Sen WEI Zhigang li Hongyu liU haisu WAN Zhi-hao WU Ke XU Qinghua ZHOU Tianjin Key Laboratory o fLung Cancer Metastasis and Tumor Environment Tianjin Lung Cancer Institute Tianjin Medical University General Hospital Tianjin 300052 China Department of Medical Oncology Chengdu 410 Hospital Chengdu 610000 China The Key Laboratory of Lung Cancer Molecular Biology of Sichuan Province West China Hospital Sichuan University Chengdu 610041 China

Background and objective Lung Cancer is one of the most malignant cancers threatening people’s health and life and one of the most rapid increasing cancers both in morbidity

关键词：肺癌癌细胞扩散治疗