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Incidence, Clinical Presentation and Angiographic Findings among Patients with Coronary Artery Ectasia in Gaza

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Health 2024年第3期16卷 234-241页

作者： mohammed habib Cardiology Department Alshifa Hospital Gaza Palestine

Background: Coronary artery ectasia (CAE) is a rare form of aneurysmal coronary heart disease. This condition increases risk of ischemia that leaded to stable angina pectoris and also acute coronary syndrome. Objective: To evaluate the incidence of CAE and to analyze clinical and angiographic characteristics among patients with symptomatic coronary artery disease. Methods: Retrospective trial of diagnostic coronary angiography which was performed at Alshifa hospital in Gaza, included all patients with coronary heart disease and underwent diagnostic coronary angiography from March 2014 to March 2023. We evaluate the incidence, clinical presentation and angiographic findings of patients with symptomatic coronary ectasia. Results: Of the 12,534 angiograms analyzed, CAE was found in 539 patients, an incidence of 4.3%. The mean age was 59.2 ± 11.7 years, and male gender predominate 81.8%. A 285 (52.9%) of patients found to have single ectatic vessel at their angiographic results. In two vessels 120 patients (22.3%), in three vessels 95 patients (17.6%) and in three vessel plus left main in 39 patients (7.2%). 70.9% angiograms showed pure ectasia without associated significant stenotic lesions in the same vessel. The right coronary artery (RCA) was the commonest affected vessel by ectasia. The most common presentation of patients is non ST segment elevation acute coronary syndrome. Conclusion: The incidence of coronary ectasia was 4.3%. Non ST segment elevation acute coronary syndrome was the most common clinical presenting. Only 30% of patients have additionally significant coronary artery stenosis. The majority of patients had single vessel involvement and right coronary artery was the most common involved vessel. Despite a dapper understanding of CAE in last years, there are still come critical issues about optimal treatment. Large multicenter randomized control trials are recommended to guide the clinician in the management of this complex sitting of patients.

关键词： CAE STEMI Non-STE-ACS Stable Angina Pectoris

Posture Detection of Heart Disease Using Multi-Head Attention Vision Hybrid(MHAVH)Model

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Computers, Materials & Continua 2024年第5期79卷 2673-2696页

作者： Hina Naz Zuping Zhang mohammed Al-habib Fuad A.Awwad Emad A.A.Ismail Zaid Ali Khan School of Computer Science and Engineering Central South UniversityChangsha410003China Department of Quantitative analysis College of Business AdministrationKing Saud UniversityP.O.Box 71115Riyadh11587Saudi Arabia Electrical and Computer Engineering University of VictoriaVictoriaV9A1B8Canada

Cardiovascular disease is the leading cause of death *** disease causes loss of heart muscles and is also responsible for the death of heart cells,sometimes damaging their functionality.A person’s life may depend on receiving timely assistance as soon as ***,minimizing the death ratio can be achieved by early detection of heart attack(HA)*** the United States alone,an estimated 610,000 people die fromheart attacks each year,accounting for one in every four ***,by identifying and reporting heart attack symptoms early on,it is possible to reduce damage and save many lives *** objective is to devise an algorithm aimed at helping individuals,particularly elderly individuals living independently,to safeguard their *** address these challenges,we employ deep learning *** have utilized a vision transformer(ViT)to address this ***,it has a significant overhead cost due to its memory consumption and computational complexity because of scaling dot-product ***,since transformer performance typically relies on large-scale or adequate data,adapting ViT for smaller datasets is more *** response,we propose a three-in-one steam model,theMulti-Head Attention Vision Hybrid(MHAVH).Thismodel integrates a real-time posture recognition framework to identify chest pain postures indicative of heart attacks using transfer learning techniques,such as ResNet-50 and VGG-16,renowned for their robust feature extraction *** incorporatingmultiple heads into the vision transformer to generate additional metrics and enhance heart-detection capabilities,we leverage a 2019 posture-based dataset comprising RGB images,a novel creation by the author that marks the first dataset tailored for posture-based heart attack *** the limited online data availability,we segmented this dataset into gender categories(male and female)and conducted testing on both segmented and original dat

关键词： Image analysis posture of heart attack(PHA)detection hybrid features VGG-16 ResNet-50 vision transformer advance multi-head attention layer

Ethmoidal Polyposis, Adenoid Hypertrophy and Tympanic Membrane Perforation—A Case Report

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第3期13卷 178-186页

作者： Ahmad Mahmud mohammed bello Fufore Abubakar Umar Hamisu abdullahi Thomas Musa Samdi Auwal Adamu Onyekwere George B. Nwaorgu Department of Otorhinolaryngology Modibbo Adama University/Modibbo Adama University Teaching Hospital Yola Nigeria Department of Otorhinolaryngology Bayero University/Aminu Kano Teaching Hospital Kano Nigeria National Ear Care Centre (NECC) Kaduna Nigeria Department of ENT Abubakar Tafawa Balewa Teaching Hospital Bauchi Nigeria Department of ENT Federal University of Health Sciences Azare Bauchi Nigeria Department of Otorhinolaryngology University College Hospital Ibadan/College of Medicine University of Ibadan Ibadan Nigeria

Background: Ethmoidal polyposis coexisting with adenoid enlargement and tympanic membrane perforation is a rare condition in otolaryngological practice. Evidences have shown that antrochoanal polyp often times coexists with adenoid enlargement especially in the young which was in sharp contrast to ethmoidal polyposis occurring in the presence of adenoid enlargement. Moreover, the hidden location of nasopharynx housing the adenoids, coupled with the masking effect of bilateral sinonasal polyps, leads to inadvertent misdiagnosis of this complex pathology with subsequent difficulty in providing effective management. Case Presentation: A 24 year-old lady presented with recurrent bilateral nasal obstruction that became persistent associated with nasal discharge and anosmia. She also had recurrent right otorrhoea with associated hearing loss. Diagnostic rigid nasal endoscopy revealed mucoid discharge with bilateral polypoid masses filling both nasal cavities. Otoendoscopic finding revealed a small (about 5%) central tympanic membrane perforation. A clinical assessment of chronic rhinosinusitis with nasal polyposis complicated by chronic suppurative otitis media (CSOM) was made. A non-contrast CT scan of the paranasal sinuses showed isodense lesions in the nasal cavities, all paranasal sinuses and the entire nasopharynx. She had endoscopic sinus surgery and a nasopharyngeal clearance biopsy. The nasal, paranasal and nasopharyngeal masses had histologic confirmation of inflammatory nasal polyps and lymphoid (adenoid) hyperplasia respectively. Her condition improved remarkably with subsequent medical treatment. She was followed up for 8 months and no recurrence was observed. Conclusion: Sinonasal polyposis can coexist with adenoid hypertrophy and middle ear disease as a single pathological condition. Hence, a high index of suspicion and thorough evaluation become necessary for making timely diagnoses and instituting effective management.

关键词： Sino-Nasal Polyps Adenoid Enlargement Rhinosinusitis Otitis Media Endoscopic Sinus Surgery

Classification, Tectonic Setting, and Mineralization Potential of Ayetoro and Sasaro Syenitic Plutons in Igarra Schist Belt, Southwestern Nigeria

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International Journal of Geosciences 2024年第6期15卷 493-510页

作者： mohammed Olatoye Adepoju Yinusa Ayodele Asiwaju-bello Department of Applied Geology Federal University of Technology Akure Nigeria

Petrographic and geochemical studies of syenite-looking Ayetoro and Sasaro plutons within Igarra Schist Belt were carried out in order to classify them and determine their tectonic setting and mineralization potential. Petrographic study and geochemical classification revealed that while Ayetoro boss is microgranite constituting an aggregate of medium grained muscovite, quartz and biotite minerals, Sasaro stock is micromonzonite made up of medium grained albite, orthoclase, biotite, hornblende and pyroxene. Geotectonic setting showed the boss and stock are orogenic, probably derived from the same upper mantle magma as Igarra batholith that got contaminated by crustal materials responsible for their difference in lithology. Their mineralization potential showed that the massive Ayetoro microgranite with no appreciable trace-element contents cannot serve as host of any metallic deposit, and should be suitable for industrial applications. Whereas, the silicified, highly sheared Sasaro monzonite, with elevated level of some trace elements contents as Ag, Au and Cu, could harbor Ag-Au-Cu deposit.

关键词： ICP-MS Microgranite Micromonzonite Orogenic Ag-Au-Cu Deposit Igarra Schist Belt

Predictive modelling of volumetric and Marshall properties of asphalt mixtures modified with waste tire-derived char:A statistical neural network approach

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Journal of Road Engineering 2024年第3期4卷 318-333页

作者： Nura Shehu Aliyu Yaro Muslich Hartadi Sutanto Noor Zainab habib Aliyu Usman Abiola Adebanjo Surajo Abubakar Wada Ahmad Hussaini Jagaba Department of Civil and Environmental Engineering Universiti Teknologi PETRONASSeri Iskandar 32610Malaysia Department of Civil Engineering Ahmadu Bello UniversityZaria 810107Nigeria Institute of Infrastructure and Environment Heriot-Watt UniversityDubai 294345United Arab Emirates School of Civil Engineering Central South UniversityChangsha 410075China Interdisciplinary Research Centre for Membranes and Water Security King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia

The goals of this study are to assess the viability of waste tire-derived char(WTDC)as a sustainable,low-cost fine aggregate surrogate material for asphalt mixtures and to develop the statistically coupled neural network(SCNN)model for predicting volumetric and Marshall properties of asphalt mixtures modified with *** study is based on experimental data acquired from laboratory volumetric and Marshall properties testing on WTDCmodified asphalt mixtures(WTDC-MAM).The input variables comprised waste tire char content and asphalt binder *** output variables comprised mixture unit weight,total voids,voids filled with asphalt,Marshall stability,and *** coupled neural networks were utilized to predict the volumetric and Marshall properties of asphalt *** predictive modeling,the SCNN model is employed,incorporating a three-layer neural network and preprocessing techniques to enhance accuracy and *** optimal network architecture,using the collected dataset,was a 2:6:5 structure,and the neural network was trained with 60%of the data,whereas the other 20%was used for cross-validation and testing *** network employed a hyperbolic tangent(tanh)activation function and a feed-forward *** to the results,the network model could accurately predict the volumetric and Marshall *** predicted accuracy of SCNN was found to be as high value>98%and low prediction errors for both volumetric and Marshall *** study demonstrates WTDC's potential as a low-cost,sustainable aggregate *** SCNN-based predictive model proves its efficiency and versatility and promotes sustainable practices.

关键词： Waste tire Neural network Sustainable practices Asphalt mixtures Predictive model

Fecal calprotectin in pediatric gastrointestinal diseases:Pros and cons

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World Journal of Clinical Pediatrics 2024年第2期13卷 198-220页

作者： mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Reem Elbeltagi Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Pediatrics University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain Department of Pediatrics University Medical CenterDr.Sulaiman Al Habib Medical GroupBahrainManama 26671ManamaBahrain Medical Microbiology Section Department of PathologySalmaniya Medical ComplexMinistry of HealthKingdom of BahrainManama 12ManamaBahrain Medical Microbiology Section Department of PathologyIrish Royal College of SurgeonBahrainBusaiteen 15503MuharraqBahrain Department of Pulmonology Faculty of MedicineTanta UniversityTanta 31527AlghrabiaEgypt Department of Pulmonology University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain Department of Pulmonology University Medical CenterKing Abdulla Medical CityDr.Sulaiman Al Habib Medical GroupManama 26671ManamaBahrain Department of Medicine The Royal College of Surgeons in Ireland-BahrainBusiateen 15503MuharraqBahrain

BACKGROUND Fecal calprotectin is a valuable biomarker for assessing intestinal inflammation in pediatric gastrointestinal ***,its role,pros,and cons in various conditions must be comprehensively *** To explore the role of fecal calprotectin in pediatric gastrointestinal diseases,including its advantages and *** A comprehensive search was conducted on PubMed,PubMed Central,Google Scholar,and other scientific research engines until February 24,*** review included 88 research articles,56 review articles,six metaanalyses,two systematic reviews,two consensus papers,and two letters to the *** Fecal calprotectin is a non-invasive marker for detecting intestinal inflammation and monitoring disease activity in pediatric conditions such as functional gastrointestinal disorders,inflammatory bowel disease,coeliac disease,coronavirus disease 2019-induced gastrointestinal disorders,gastroenteritis,and cystic fibrosis-associated intestinal ***,its lack of specificity and susceptibility to various confounding factors pose challenges in *** these limitations,fecal calprotectin offers significant advantages in diagnosing,monitoring,and managing pediatric gastrointestinal *** Fecal calprotectin holds promise as a valuable tool in pediatric gastroenterology,offering insights into disease activity,treatment response,and *** protocols and guidelines are needed to optimize its clinical utility and mitigate interpretation *** research is warranted to address the identified limitations and enhance our understanding of fecal calprotectin in pediatric gastrointestinal diseases.

关键词： Fecal calprotectin Pediatric gastrointestinal diseases Functional gastrointestinal disorders Inflammatory bowel disease Coeliac disease COVID-19-induced gastrointestinal disorders Infectious gastroenteritis Cystic fibrosis

Metabolomic changes in children with autism

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World Journal of Clinical Pediatrics 2024年第2期13卷 171-197页

作者： mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Reem Elbeltagi Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671Bahrain Department of Pediatric University Medical CenterDr.Sulaiman Al Habib Medical GroupManamaBahrainManama 26671Bahrain Medical Microbiology Section Department of PathologySalmaniya Medical ComplexMinistry of HealthKingdom of BahrainManama 12Bahrain Medical Microbiology Section Department of PathologyIrish Royal College of SurgeonBahrainBusaiteen 15503MuharraqBahrain Department of Pulmonology Faculty of MedicineTanta UniversityTanta 31527AlghrabiaEgypt Department of Chest Disease University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671Bahrain Department of Chest Disease University Medical CenterDr.Sulaiman Al Habib Medical GroupManamaManama 26671Bahrain Department of Medicine The Royal College of Surgeons in Ireland-BahrainBusiateen 15503MuharraqBahrain

BACKGROUND Autism spectrum disorder(ASD)is a neurodevelopmental condition characterized by deficits in social communication and repetitive *** profiling has emerged as a valuable tool for understanding the underlying metabolic dysregulations associated with *** To comprehensively explore metabolomic changes in children with ASD,integrating findings from various research articles,reviews,systematic reviews,meta-analyses,case reports,editorials,and a book *** A systematic search was conducted in electronic databases,including PubMed,PubMed Central,Cochrane Library,Embase,Web of Science,CINAHL,Scopus,LISA,and NLM catalog up until January *** criteria encompassed research articles(83),review articles(145),meta-analyses(6),systematic reviews(6),case reports(2),editorials(2),and a book chapter(1)related to metabolomic changes in children with *** criteria were applied to ensure the relevance and quality of included *** The systematic review identified specific metabolites and metabolic pathways showing consistent differences in children with ASD compared to typically developing *** metabolic biomarkers may serve as objective measures to support clinical assessments,improve diagnostic accuracy,and inform personalized treatment *** profiling also offers insights into the metabolic alterations associated with comorbid conditions commonly observed in individuals with *** Integration of metabolomic changes in children with ASD holds promise for enhancing diagnostic accuracy,guiding personalized treatment approaches,monitoring treatment response,and improving *** research is needed to validate findings,establish standardized protocols,and overcome technical challenges in metabolomic *** advancing our understanding of metabolic dysregulations in ASD,clinicians can improve the lives of affected individuals and their families.

关键词： Autism spectrum disorder Metabolic dysregulations Metabolomic changes Children Mitochondrial dysfunction Oxidative stress Amino acids

Microphallus early management in infancy saves adulthood sensual life:A comprehensive review

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World Journal of Clinical Pediatrics 2024年第2期13卷 16-37页

作者： mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Majed A Shaikh Reem Elbeltagi Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511Egypt Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671Bahrain Department of Pediatric University Medical CenterSulaiman Al Habib Medical GroupManama 26671Bahrain Department of Medical Microbiology Section and Pathology Salmaniya Medical ComplexMinistry of HealthKingdom of BahrainManama 12Bahrain Department of Medical Microbiology Section and Pathology Irish Royal College of SurgeonBusaiteen 15503Bahrain Department of Pulmonology Faculty of MedicineTanta UniversityTanta 31527Egypt Department of Pulmonology University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671Bahrain Department of Pulmonology University Medical CenterSulaiman Al Habib Medical GroupManama 26671Bahrain Department of Pediatrics Ibn Al Nafees HospitalManama 54533Bahrain Department of Medicine The Royal College of Surgeons in Ireland-BahrainBusiateen 15503Bahrain

Microphallus/Micropenis is a rare condition with significant physical and psychological implications for affected *** article comprehensively reviews micropenis,its etiology,epidemiology,and various treatment *** conducted a thorough literature review to collect relevant information on micropenis and microphallus,as well as related *** primary databases were PubMed,Medline,and Google *** searched for articles published in English between 2000 and *** analysis included 67 review articles,56 research studies,11 case reports,one guideline,and one *** search terms included"microphallus","micropenis","congenital hypogonadotropic hypogonadism","androgen insensitivity syndrome","pediatric management of micropenis","testosterone therapy",and"psychosocial implications of micropenis".We focused on diagnosing micropenis and related conditions,including hormonal assessments,medical and surgical treatment options,psychosocial and psychological well-being,sexual development of adolescents,and sociocultural influences on men's perceptions of penile ***,we explored parenting and family dynamics in cases of micropenis and disorders of sex development,implications of hormonal treatment in neonates,and studies related to penile augmentation procedures and their *** article highlights the importance of early diagnosis and intervention in addressing the physical and psychological well-being of individuals with *** procedures,such as penile lengthening and girth enhancement,and non-surgical approaches like hormonal therapy are *** significance of psychological support,education,and lifestyle modifications is *** management and comprehensive care are crucial for individuals with micropenis,from infancy to adolescence and beyond.A multidisciplinary approach involving urologists,endocrinologists,and mental health professionals is *** assessment of treatment e

关键词： Microphallus Micropenis Hypogonadism Children Adults Sensual life Testosterone therapy

Gastrointestinal tolerability of organic infant formula compared to traditional infant formula: A systematic review

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World Journal of Clinical Pediatrics 2024年第1期13卷 125-140页

作者： mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Reem Elbeltagi Mohamed Basiony Hamza Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityDr.Sulaiman Al Habib Medical GroupManama 26671ManamaBahrain Medical Microbiology Section Department of PathologySalmaniya Medical ComplexMinistry of HealthKingdom of BahrainManama 12ManamaBahrain Medical Microbiology Section Department of PathologyIrish Royal College of SurgeonBusaiteen 15503MuharraqBahrain Department of Pulmonology Faculty of MedicineTanta UniversityTanta 31527AlghrabiaEgypt Department of Pulmonology University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityDr.Sulaiman Al Habib Medical GroupManama 26671ManamaBahrain Department of Medicine The Royal College of Surgeons in Ireland-BahrainBusiateen 15503MuharraqBahrain Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlgahrbiaEgypt

BACKGROUND Infants'nutrition significantly influences their growth,development,and overall *** the increasing demand for organic infant formula driven by the perception of health benefits and growing awareness of natural feeding options,it is crucial to conduct a comparative analysis of the gastrointestinal tolerability between organic and traditional infant *** To provide a concise and precise analysis of the gastrointestinal tolerability of organic infant formula compared to traditional infant *** to limited direct comparisons,the review synthesizes available literature on each formula type,presenting insights into their potential effects on infants'digestive *** An extensive literature search was conducted,compiling studies on organic and traditional infant formulas,their compositions,and reported effects on gastrointestinal *** searched academic databases such as PubMed and Google Scholar and specialized nutrition,paediatrics,and infant health journals using relevant keywords till October 1,*** Although specific comparative studies are scarce and formula heterogeneity is a significant limitation,this systematic review provides an in-depth understanding of organic infant formulas'composition and potential *** scientific evidence directly comparing gastrointestinal tolerability is limited,organic formulas strive to use carefully selected organic ingredients to imitate breast milk *** benefits include improved lipid profiles,higher methionine content,and decreased antibiotic-resistant bacteria *** the gastrointestinal tolerability of organic and traditional infant formulas is crucial for parents and healthcare providers to make informed *** Despite limitations in direct comparisons,this systematic review provides insights into the composition and potential benefits of organic infant *** emphasizes the need for further research to eluci

关键词： Organic infant formula Traditional infant formula Gastrointestinal tolerability Formula ingredients Digestive health Infant nutrition Organic farming