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低出生体重儿的氨基酸、谷氨酰胺以及蛋白质代谢

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世界核心医学期刊文摘（儿科学分册） 2006年第A10期2卷 53-53页

作者： Parimi P.S. Kadrofske m.m. Gruca L.L. 高蕊 Schwartz Center for metabolism and Nutrition G 735 MetroHealth Medical Center 2500 MetroHealth Dr. Cleveland OH 44109 United StatesDr.

Glutamine has been proposed to be conditionally essential for premature infants, and the currently used parenteral nutrient mixtures do not contain glutamine. De novo glutamine synthesis (DGln) is linked to inflow of carbon into and out of the tricarboxylic acid (TCA) cycle. We hypothesized that a higher supply of parenteral amino acids by increasing the influx of amino acid carbon into the TCA cycle will enhance the rate of DGln. Very low birth weight infants were randomized to receive parenteral amino acids either 1.5 g/kg/d for 20 h followed by 3.0 g/kg/d for 5 h (AA1.5) or 3.0 g/kg/d for 20 h followed by 1.5 g/kg/d for 5 h (AA3.0). A third group of babies received amino acids 1.5 g/kg/d for 20 h followed by 3.0 g/kg/d for 20 h (AA- Ext). Glutamine and protein/nitrogen kinetics were examined using [5- 15N]glutamine, [2h5]phenylalanine, [1- 13C,15N] leucine, and [15N2]urea tracers. An acute increase in parenteral amino acid infusion for 5 h (AA1.5) resulted in decrease in rate of appearance (ra) of phenylalanine and urea, but had no effect on glutamine ra. Infusion of amino acids at 3.0 g/kg/d for 20 h resulted in increase in DGln, leucine transamination, and urea synthesis, but had no effect on ra phenylalanine (AA- Ext). These data show an acute increase in parenteral amino acid- suppressed proteolysis, however, such an effect was not seen when amino acids were infused for 20 h and resulted in an increase in glutamine synthesis.

关键词：蛋白质代谢补充治疗必需营养素三羧酸循环肠外营养从头合成合成作用碳离子抑制作用示踪剂

房颤伴晚期慢性心力衰竭患者中低心率与高心率的比较:对临床状况、神经内分泌及存活率的影响

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世界核心医学期刊文摘（心脏病学分册） 2006年第9期2卷 37-37页

作者： Rienstra m. Van Gelder I.C. Van Den Berg m.P. 孙凯 Department of Cardiology University Medical Center GroningenUniversity of GroningenP.O.Box 30.0019700 RB GroningenNetherlands

Background: Atrial fibrillation is common in chronic heart failure. Long-term restoration of sinus rhythm is generally unsuccessful. It may be speculated tha t higher heart rates are unfavorable, since this may lead to tachycardiomyopathy , but there are no data which have examined this. methods and results: Seventy- seven patients with atrial fibrillation and advanced chronic heart failure, age 70±7 years, left-ventricular ejection fraction 0.23±0.08, 61%with ischemic e tiology were included. Patients were dichotomized according to the median heart rate(80 bpm) at inclusion(39 patients with “low”heart rate and 38 patients wit h “high”heart rate). At baseline, both patient groups were remarkably comparab le. After a mean follow-up of 3.3±0.9 years, mortality was comparable(62%vers us 55%, p=non-significant). An independent relation was found between lower he art rate and survival, in addition to absence of hypertension, digoxin use, and higher N-ANP, dopamine, and renin levels. Conclusion: In the present analysis, patients with atrial fibrillation and advanced chronic heart failure with higher heart rates are comparable to those with lower heart rates. Not higher heart ra tes at baseline but, on the contrary, lower heart rates seem associated with a w orse outcome.

关键词：慢性心力衰竭患者神经内分泌心率临床状况房颤晚期存活率心动过速性心肌病

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经导管房间隔缺损封堵术后心脏重构的时程

世界核心医学期刊文摘（心脏病学分册） 2007年第2期3卷 48-48页

作者： Pascotto m. Santoro G. Cerrato F. 刘少伟 Division of Cardiology A.O.Monaldi 2nd University of Naples Naples Italy

背景:众所周知,房间隔缺损(ASD)分流导致的心脏后果包括右房扩张和由右向左的容积失衡,这两种变化又可解释其大部分远期并发症。因此,减轻心脏容积负荷是ASD封堵术的一个主要目标。与手术方式不同,经导管方式可看作是评价ASD封堵术后心... 详细信息

背景:众所周知,房间隔缺损(ASD)分流导致的心脏后果包括右房扩张和由右向左的容积失衡,这两种变化又可解释其大部分远期并发症。因此,减轻心脏容积负荷是ASD封堵术的一个主要目标。与手术方式不同,经导管方式可看作是评价ASD封堵术后心脏形态重构的一种“无偏倚”的方法。方法:纳入42例无症状的患者(年龄22±18岁),利用大ASD(平均直径17±6mm,QP/QS 2.2±0.9)经皮封堵术后24h、1个月和6个月时的超声心动图检查评估心脏形态变化的程度和时程。

关键词：心脏重构封堵术超声心动图容积负荷房间隔缺损房间隔封堵器 Amplatzer 舒张期末堵闭

Fungal diversity notes 1611-1716: taxonomic and phylogenetic contributions on fungal genera and species emphasis in south China

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Fungal Diversity 2023年第5期122卷 161-403页

作者： Indunil C.Senanayake Walter Rossi marco Leonardi Alex Weir mark mchugh Kunhiraman C.rajeshkumar rajnish K.Verma Samantha C.Karunarathna Saowaluck Tibpromma Nikhil Ashtekar Sreejith K.Ashtamoorthy Sanjay raveendran Gurmeet Kour Aishwarya Singh Saúl De la Peña-Lastra Antonio mateos miroslav Kolařík Vladimír Antonín hanaŠevčíková Fernando Esteve-raventós Ellen Larsson Fermín Pancorbo Gabriel moreno Alberto Altés Yolanda Turégano Tian-Ye Du Li Lu Qi-Rui Li Ji-Chuan Kang Sugantha Gunaseelan Kezhocuyi Kezo malarvizhi Kaliyaperumal Jizhen Fu milan C.Samarakoon Yusufjon Gafforov Shakhnoza Teshaboeva Pradeep C.Kunjan Arya Chamaparambath Adam Flakus Javier Etayo Pamela Rodriguez-Flakus mikhail P.Zhurbenko Nimali Ide Silva Danushka S.Tennakoon KPDeepna Latha Patinjareveettil manimohan KNAnil raj mark S.Calabon Abdollah Ahmadpour Zeinab heidarian Zahra Alavi Fatemeh Alavi Youbert Ghosta razmig Azizi mei Luo min-Ping Zhao Nuwan D.Kularathnage Li hua Yun-hui Yang Chun-Fang Liao hai-Jun Zhao Anis S.Lestari Subashini C.Jayasiri Feng-ming Yu Lei Lei Jian-Wei Liu Omid Karimi Song-ming Tang Ya-Ru Sun Yong Wang ming Zeng Zin h.htet Benedetto T.Linaldeddu Artur Alves Alan J.L.Phillips Carlo Bregant Lucio montecchio AndréDe Kesel Vincent P.hustad Andrew N.miller Anna G.Fedosova Viktor Kučera mubashar raza muzammil hussain Yan-Peng Chen Vinodhini Thiyagaraja Deecksha Gomdola Achala R.rathnayaka Asha J.Dissanayake Nakarin Suwannarach Sinang hongsanan Sajeewa S.N.maharachchikumbura Lakmali S.Dissanayake Nalin N.Wijayawardene Rungtiwa Phookamsak Saisamorn Lumyong E.B.Gareth Jones Neelamanie Yapa Dhanushka N.Wanasinghe Ning Xie mingkwan Doilom Ishara S.manawasinghe Jian-Kui(Jack)Liu Qi Zhao Biao Xu Kevin D.hyde Jiage Song Innovative Institute for Plant health/Key Laboratory of Green Prevention and Control On Fruits and Vegetables in South China Ministry of Agriculture and Rural AffairsZhongkai University of Agriculture and EngineeringHaizhu DistrictGuangzhou 510225GuangdongChina Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Guangdong Provincial Key Laboratory for Plant Epigenetics College of Life Science and OceanographyShenzhen University3688Nanhai AvenueNanshanShenzhen 518055GuangdongChina Sect.Environmental Sciences Department MeSVAUniversity of L’AquilaVia Vetoio67100 CoppitoAQItaly Department of Environmental Biology SUNY-ESF241 Illick Hall1 Forestry DriveSyracuseNY 13210USA National Fungal Culture Collection of India MACS Agharkar Research InstitutePuneMaharashtra 411004India Department of Plant Pathology Punjab Agricultural UniversityLudhianaPunjab 141004India Center for Yunnan Plateau Biological Resources Protection and Utilization College of Biological Resource and Food EngineeringQujing Normal UniversityQujing 655011YunnanChina Department of Forest Ecology Kerala Forest Research InstitutePeechiThrissurKerala 680653India Department of Botany The American CollegeTallakkulamMaduraiTamil Nadu 625002India Department of Zoology Savitribai Phule Pune UniversityGaneshkhind RdGaneshkhindPuneMaharashtra 411007India University of Santiago de Compostela 15782 Santiago de CompostelaSpain Sociedad micológica Extremeña C/Sagitario 1410001 CáceresSpain Institute of microbiology of the Czech Academy of Sciences Vídeňská108314220 Prague 4Czech Republic Department of Botany Moravian MuseumZelnýtrh 665937 BrnoCzech Republic Department of Life Sciences(Botany Unit) University of Alcalá28805 Alcaláde HenaresMadridSpain Biological and Enviromental Sciences University of Gothemburgand Gothemburg Global Biodiversity CentreBox 46140530 GöteborgSweden madrid mycological Society Real Jardín BotánicoC/Claudio Moyano 128014 MadridSpain State Ke

This article is the 15th contribution in the Fungal Diversity Notes series,wherein 115 taxa from three phyla,nine classes,28 orders,48 families,and 64 genera are *** taxa described and illustrated in the present study include a new family,five new genera,61 new species,five new combinations,one synonym,one new variety and 31 records on new hosts or new geographical *** *** introduced and accommodated in *** new genera introduced in this study are Ageratinicola,Kevinia,Pseudomultiseptospora(Parabambusicolaceae),marasmiellomycena,and Vizzinia(Porotheleaceae).Newly described species are Abrothallus altoandinus,Ageratinicola kunmingensis,Allocryptovalsa aceris,Allophoma yuccae,Apiospora cannae,***,***,Boeremia wisteriae,Calycina papaeana,Clypeo-coccum lichenostigmoides,Coniochaeta riskali-shoyakubovii,Cryphonectria kunmingensis,Diaporthe angustiapiculata,***,***,Diatrypella guangdongense,Dothiorella franceschinii,Endocalyx phoenicis,Epicoc-cum terminosporum,Fulvifomes karaiensis,***,Ganoderma ghatensis,hysterobrevium baoshanense,Inocybe avellaneorosea,***,Jahnula oblonga,Kevinia lignicola,Kirschsteiniothelia guangdongensis,Laboulbenia caprina,***,***,***,***,***,***,***,***,Laccaria rubriporus,Lasiodiplodia morindae,Lyophyllum agnijum,marasmiellomycena pseudoomphaliiformis,melomastia beihaiensis,Nemania guangdongensis,Nigrograna thailandica,Nigrospora ficuum,Oxydothis chinensis,***,Petriella thailandica,Phaeoacremonium chinensis,Phialocephala chinensis,Phytophthora debattistii,Polyplosphaeria nigrospora,Pronectria loweniae,Seriascoma acutispora,Setoseptoria bambusae,Stictis anomianthi,Tarzetta tibetensis,Tarzetta urceolata,Tetraploa obpyriformis,Trichoglossum beninense,and Tricoderma *** provide an emendation for Urnula ailaoshanensis Agaricus duplocingulatoides *** i

关键词： Agaricomycetes Ascomycota Basidiomycota Dothideomycetes Eurotiomycetes Fungal diversity Geoglossomycetes Geographical distribution host records Incertae sedis Laboulbeniomycetes Lecanoromycetes Leotiomycetes Novel taxa New combination Oomycota Peronosporea Pezizomycetes Phylogeny Sordariomycetes South Chinese fungi Taxonomy

One stop shop:backbones trees for important phytopathogenic genera:Ⅰ(2014)

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Fungal Diversity 2014年第4期 21-125页

作者： Kevin D.hyde R.henrik Nilsson S.Aisyah Alias hiran A.Ariyawansa Jaime E.Blair Lei Cai Arthur W.A.m.de Cock Asha J.Dissanayake Sally L.Glockling Ishani D.Goonasekara michal Gorczak matthias hahn Ruvishika S.Jayawardena Jan A.L.van Kan matthew h.Laurence C.AndréLévesque Xinghong Li Jian-Kui Liu Sajeewa S.N.maharachchikumbura Dimuthu S.manamgoda Frank N.martin Eric h.C.mcKenzie Alistair R.mcTaggart Peter E.mortimer Prakash V.R.Nair Julia Pawlowska Tara L.Rintoul Roger G.Shivas Christoffel F.J.Spies Brett A.Summerell Paul W.J.Taylor razak B.Terhem Dhanushka Udayanga Niloofar Vaghefi Grit Walther mateusz Wilk marta Wrzosek Jian-Chu Xu JiYe Yan Nan Zhou Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201People’s Republic of China World Agroforestry Centre East Asia NodeHeilongtanKunming 650201People’s Republic of China Institute of Excellence in Fungal Research and School of ScienceMae Fah Luang UniversityChiang Rai 57100Thailand Botany and microbiology Department College of ScienceKing Saud UniversityRiyadh 1145Saudi Arabia Department of Biological and Environmental Sciences University of GothenburgBox 46140530 GöteborgSweden Institute of Ocean and Earth Sciences(IOES) C308Institute of Postgraduate Studies BuildingUniversity of Malaya50603 Kuala LumpurMalaysia Department of Biology Franklin&Marshall CollegeLancasterPAUSA State Key Laboratory of mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101 People’s Republic of China CBS-KNAW Fungal Biodiversity Centre Uppsalalaan 83584CT UtrechtThe Netherlands Beijing Academy of Agriculture and Forestry Sciences Institute of Plant and Environment ProtectionNo.9 of ShuguanghuayuanzhongluHaidian DistrictBeijing 100097People’s Republic of China 135 Brodrick Road Eastbourne BN229RAEast SussexUK Department of Plant Systematics and Geography Faculty of BiologyUniversity of WarsawAl.Ujazdowskie 400-478WarsawPoland Department of Biology TU KaiserslauternErwin-Schrodinger-StraBe67663 KaiserslauternGermany Laboratory of Phytopathology Wageningen UniversityDroevendaalsesteeg 16708 PB WageningenThe Netherlands Royal Botanic Gardens and Domain Trust Mrs Macquaries RdSydneyNew South Wales 2000Australia Agriculture and Agri-Food Canada Central Experimental FarmOttawaONCanada United States Department of Agriculture Agriculture Research ServiceSalinasCAUSA Landcare Research Private Bag92170 AucklandNew Zealand Department of Agriculture Fisheries and ForestryEcosciences PrecinctDutton ParkQueensland 4102Australia Faculty of Veterinary and Agricultural Sciences The University of

many fungi are pathogenic on plants and cause significant damage in agriculture and *** are also part of the natural ecosystem and may play a role in regulating plant numbers/*** identification and analysis of plant pathogenic fungi,while important,is often hampered by the scarcity of discriminatory taxonomic characters and the endophytic or inconspicuous nature of these ***(DNA sequence)data for plant pathogenic fungi have emerged as key information for diagnostic and classification studies,although hampered in part by non-standard laboratory practices and analytical *** facilitate current and future research,this study provides phylogenetic synopses for 25 groups of plant pathogenic fungi in the Ascomycota,Basidiomycota,mucormycotina(Fungi),and Oomycota,using recent molecular data,up-to-date names,and the latest taxonomic *** laboratory protocols together with advice on their application,as well as general observations,are also *** hope to maintain updated backbone trees of these fungal lineages over time and to publish them jointly as new data *** of plant pathogenic fungi not covered by the present study are invited to join this future ***,Botryosphaeriaceae,Botryosphaeria,Botrytis,Choanephora,Colletotrichum,Curvularia,Diaporthe,Diplodia,Dothiorella,Fusarium,Gilbertella,Lasiodiplodia,mucor,Neofusicoccum,Pestalotiopsis,Phyllosticta,Phytophthora,Puccinia,Pyrenophora,Pythium,Rhizopus,Stagonosporopsis,Ustilago and Verticillium are dealt with in this paper.

关键词： Ascomycota Basidiomycota Endophytes mucormycotina molecular identification Oomycota Plant pathogens Protozoa

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PNAS:维生素A和C如何擦除细胞记忆?

现代生物医学进展 2017年第4期17卷 I0003-I0003页

作者： Timothy Alexander hore[a],[b], Ferdinand von meyenn[a], mirunalini ravichandran[c], martin Bachman[d],[e] Gabriella Ficz[f] David Oxley[g] Fátima Santos[a] Shankar Balasubramanian[d],[e] Tomasz P. Jurkowski[c], Wolf Reik[a],[h], [a]Epigenetics Programme Babraham Institute Cambridge CB22 3AT United Kingdom [b]Department of Anatomy University of Otago Dunedin 9016 New Zealand [c]Institute of Biochemistry University of Stuttgart 70569 Stuttgart Germany [d]Department of Chemistry University of Cambridge Cambridge CB2 1EW United Kingdom [e]Cancer Research UK Cambridge Institute University of Cambridge Cambridge CB2 0RE United Kingdom [f]Barts Cancer Institute Queen Mary University of London London EC1M 6BQ United Kingdom [g]mass Spectrometry Facility Babraham Institute Cambridge CB22 3AT United Kingdom [h]Wellcome Trust Sanger Institute Hinxton CB10 1SA United Kingdom

维生素A和C不只是对我们的健康有益，其还会影响到机体的DNA，日前一项刊登于国际杂志PNAS上的研究论文中，来自巴布拉汉研究所（Babraham Institute）等机构的研究人员通过研究揭示了维生素A和C如何修饰细胞的表观遗传记忆。相关研究... 详细信息

维生素A和C不只是对我们的健康有益，其还会影响到机体的DNA，日前一项刊登于国际杂志PNAS上的研究论文中，来自巴布拉汉研究所（Babraham Institute）等机构的研究人员通过研究揭示了维生素A和C如何修饰细胞的表观遗传记忆。相关研究或为后期研究者们开发新型再生医学疗法或者对细胞重编程提供一定的思路。

关键词：维生素A 细胞记忆擦除研究论文表观遗传研究人员再生医学

评价不可切除的肝细胞癌经动脉化疗栓塞后的长期毒副作用——单中心研究

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国际医学放射学杂志 2008年第A6期31卷 507-507页

作者： m.Buijs J.A.Vossen C.Frangakis C.S.Georgiades 贺李 the Russell h. morgan Department of radiology and ra-diological Sciences Division of Vascular and Interventional Radiology Johns Hopkins Hospital 600 N Wolfe St Blalock 545 Baltimore MD 21287.

目的评价肝细胞癌(hCC)病人经动脉化疗栓塞治疗(TACE)后6个月及1a的毒副作用。病例均进行规范化肿瘤治疗,可以与全身化疗的肝癌病人比较。材料及方法

关键词：经动脉化疗栓塞肝细胞癌毒副作用肝癌病人单中心伦理委员会血胆红素命名标准凝血时间血清

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怀孕期进行ERCP的安全性和有效性

世界核心医学期刊文摘（胃肠病学分册） 2005年第2期1卷 34-34页

作者： Kahaleh m. hartwell G.D. Arseneau K.O. P. Yeaton 赵丽娜 Digestive health Center Radiation Oncology Physics Dept. Anesth. Univ. Virginia H. Charlottesv illeVA United StatesDr.

Background Choledocholithiasis during pregnancy increases the risk of morbidit y and mortality for both fetus and mother because of cholangitis and pancreatiti s. ERCP has been advocated as safe and effective in pregnant women, but fetal ra diation exposure is not routinely monitored. The aim of this study was to record fetal exposure to ionizing radiation during ERCP and to assess outcome. methods Seventeen ERCPs were performed in pregnant women between January 1995 and Augus t 2003. Techniques to minimize fluoroscopy were used, and fluoroscopy times were recorded. Thermoluminescent dosimeters affixed to the skin of the mother were u sed to estimate fetal radiation exposure. Observations mean gestational age was 18.6 (8.9) weeks (range 5-33 weeks). mean fluoroscopy time was 14 (13) seconds (range 1-48 seconds). Estimated fetal radiation exposure was 40 (46) mrad (rang e 1-180 mrad).There was a correlation between fluoroscopy time and radiation ex posure, but there was a wide range of radiation exposure for individual fluorosc opy times. Complications included postsphincterotomy bleeding in one patient (co ntrolled by hemoclip placement) and post-ERCP pancreatitis in one patient that necessitated 3 days of hospitalization. Two women developed third-trimester pre eclampsia, and labor was induced in *** of the 15 patients who deliver ed were contacted and they confirmed that their child was in good health. Conclu sions ERCP with modified techniques is safe during *** should be routinely recorded.

关键词：电离辐射母婴死亡率妊娠时间胆总管结石热释光括约肌切开术透视检查止血夹先兆子痫量仪