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Two Dimensional Density FlUCtuation Measurements During the Non-Inductive Current Ramp-up Phase in the Compact Plasma Wall Interaction Experimental Device CPD

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Plasma Science and Technology 2009年第4期11卷 397-401页

作者： h.zushi T.RYOUKAI K.KIKUKAWA T.MORISAKI R.BhATTAChARYAY T.YOShINAGA K.hANADA T.SAKIMURA h.IDEI K.DONO N.NIShINO h.hONMA S.TAShIMA T.MUTOh S.KUBO K.NAGASAKI M.SAKAMOTO Y.NAKAShIMA Y.hIGAShIZONO K.N.SATO K.NAKAMURA M.hASEGAWA S.KAWASAKI h.NAKAShIMA A.hIGAShIJIMA RIAM Kyushu University IGSES Kyushu University National Institute for Fusion Science hiroshima University Kyoto University University of Tsukuba

Two-dimensional structure of density fluctuations is examined during the current jump phase, indicating a change from the open magnetic fields to the closed ones. During the smooth current ramp-up phase the two-dimensional contour of the LiI intensity shows vertically alignment, consistent with the magnetic surfaces. At the inflection point in Ip ramp-up the LiI intensity contour becomes flat in the observation regime and then suddenly a steep gradient and higher intensity regime are formed in the vertical direction. This higher intensity corresponds to a burst of LiI waveform. According to these changes in the contour, it is found that, within ~1 ms around the burst of LiI, a low frequency coherent wave with a long wavelength rapidly grows. The relations with other signals （magnetic flux and microwave stray power） are discussed with respect to the topological change in the magnetic configuration and mode conversion of the incident electromagnetic waves.

关键词： Li sheet beam density fluctuations current ramp-up spherical tokamak

Non-Inductive Start up of QUEST Plasma by RF Powert

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Plasma Science and Technology 2011年第3期13卷 307-311页

作者： K. hANADA h. zushi h. IDEI K. NAKAMURA M. IShIGURO S. TAShIMA E. I. KALINNIKOVA M. SAKAMOTO M. hASEGAWA A. FUJISAWA A. hIGAShIJIMA S. KAWASAKI h. NAKAShIMA h. LIU O. MITARAI T. MAEKAWA A. FUKUYAM Y. TAKASE J. QIAN Research Institute for Applied Mechanics Kyushu University Japan Interdisciplinary Graduate School of Engineering Science Kyushu University Japan School of Industrial Engineering Tokai University Japan Graduate School of Energy Science Kyoto University Japan Graduate School of Technology Kyoto University Japan Graduate School of Frontier Science University of Tokyo Japan Institute of Plasma Physics Chinese Academy of Sciences China

Both start-up and sustainment of plasma were successfully achieved by fully non- inductive current drive using microwave with a frequency of 8.2 Ghz. Plasmas current of 15 kA was implemented for 1 s. Magnetic surface reconstruction exhibited a plasma shape with an aspect ratio of below 1.5. The plasma current was dependent significantly on the launched microwave power and vertical magnetic field, while not affected by the mode of launched wave and the toroidal refractive index. hard X-ray （hXR） emitted from energetic electrons accelerated by the microwave was observed, and the discharge with a plasma current over 4 kA followed the same trend as the number of photons of 10 keV to 12 keV. This suggests that the plasma current may be driven by energetic electrons. Based on the experimental conditions, alternative explanations of how the plasma current could be driven are discussed.

关键词： steady-state operation of spherical tokamak non-inductive current drive QUEST

h_∞Loop Shaping Control for Plasma Vertical Position Instability on QUEST

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Plasma Science and Technology 2013年第3期15卷 295-299页

作者：刘晓龙 Kazuo NAKAMURA Tatsuya YOShISUE Osamu MITARAI Makoto hASEGAWA Kazutoshi TOKUNAGA 薛二兵 hideki zushi Kazuaki hANADA Akihide FUJISAWA hiroshi IDEI Shoji KAWASAKI hisatoshi NAKAShIMA Aki hIGAShIJIMA Kuniaki ARAKI IGSES Kyushu University RIAM Kyushu University Tokai University

QUEST has a divertor configuration with a high and a negative n-index, and the problem of plasma vertical position instability control in QUEST is still under extensive study for achieving high efficiency plasma. The instability we considered is that the toroidal plasma moves either up or down in the vacuum chamber until it meets the vessel wall and is extinguished. The actively controlled coils （hCU and hCL） outside the vacuum vessel are serially connected in feedback with a measurement of the plasma vertical position to provide stabilizing control. In this work, a robust controller is employed by using the loop synthesis method, and provides robust stability over a wide range of n-index. Moreover, the gain of the robust controller is lower than that of a typical proportional derivative （PD） controller in the operational frequency range; it indicates that the robust controller needs less power consumption than the PD controller does.

关键词： vertical position instability robust control loop shaping QUEST

Comparative study of esomeprazole and lansoprazole in triple therapy for eradication of helicobacter pylori in Japan

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World Journal of Gastroenterology 2014年第15期20卷 4362-4369页

作者： Tsutomu Nishida Masahiko Tsujii hirohisa Tanimura Shusaku Tsutsui Shingo Tsuji Akira Takeda Atsuo Inoue hiroyuki Fukui Toshiyuki Yoshio Osamu Kishida hiroyuki Ogawa Masahide Oshita Ichizo Kobayashi Shinichiro zushi Makoto Ichiba Naoto Uenoyama Yuichi Yasunaga Ryu Ishihara Mamoru Yura Masato Komori Satoshi Egawa hideki Iijima Tetsuo Takehara Department of Gastroenterology and hepatology Osaka University Graduate School of MedicineSuitaOsaka 565-0871Japan Department of Gastroenterology Osaka Kaisei HospitalOsaka 532-0003Japan Department of Gastroenterology Itami City HospitalItami 664-8540Japan Department of Gastroenterology Osaka Seamen’s Insurance HospitalOsaka 552-0021Japan Department of Gastroenterology Ashiya Municipal HospitalAshiya 659-8502Japan Department of Gastroenterology Osaka General Medical CenterOsaka 558-8558Japan Department of Gastroenterology Yao Municipal HospitalYao 581-0069Japan Department of Gastroenterology Osaka National HospitalOsaka 540-0006Japan Department of Gastroenterology Sumitomo HospitalOsaka 565-0871Japan Department of Gastroenterology Nishinomiya Municipal Central HospitalNishinomiya 663-8014Japan Department of Internal Medicine Osaka Police HospitalOsaka 543-0035Japan Department of Gastroenterology Higashiosaka City General HospitalHigashiosaka 578- 8588Japan Department of Gastroenterology Ikeda Municipal HospitalIkeda 563-0025Japan Department of Gastroenterology Toyonaka Municipal HospitalToyonaka 560-0055Japan Department of Gastroenterology Otemae HospitalOsaka 540-0008Japan Department of Gastroenterology Hyogo Prefectural Nishinomiya HospitalNishinomiya 662-0918Japan Department of Gastrointestinal Oncology Osaka Medical Center for Cancer and Cardiovascular DiseaseOsaka 537-0025Japan Department of Gastroenterology Minoh City HospitalMinoh 562-0014Japan Department of Gastroenterology Osaka Rosai HospitalSakai 591-8025Japan Department of Gastroenterology Kansai Rosai HospitalAmagasaki 660-8511Japan

AIM: To evaluate the efficacy and safety of esomeprazole-based triple therapy compared with lansoprazole therapy as first-line eradication therapy for patients with helicobacter pylori (h. pylori) in usual post-market... 详细信息

关键词： helicobacter pylori Eradication Esomeprazole Lansoprazole Proton pomp inhibitor

Feasibility of the Routine Clinical Use of a Multiplex Virus Polymerase Chain Reaction Assay Based on Blood Virus Detection in hematopoietic Stem Cell-Transplanted Patients

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International Journal of Clinical Medicine 2022年第2期13卷 67-81页

作者： hiroko Tsunemine Miho Sasaki Yuriko zushi Toshiharu Saitoh Norio Shimizu Yasuhiro Tomaru Yumi Aoyama Ryusuke Yamamoto Tomomi Sakai Nobuyoshi Arima Taiichi Kodaka Takayuki Takahashi Departments of hematology Shinko Hospital Kobe Japan Cell Therapy Shinko Hospital Kobe Japan Center for Stem Cell and Regenerative Medicine Tokyo Medical and Dental University Tokyo Japan Akasaka hematology & Oncology Clinic Kobe Japan

Background: Multiplex virus assays are useful in immunocompromised hosts but still challenging in routine clinical settings in terms of their sensitivity, specificity, reproducibility, and time and cost performances. In recent years, we developed a qualitative multiplex virus PCR assay capable of the simultaneous detection of 13 virus species within 3 h. however, because of the multiple and concomitant nature of this virus assay, it should be validated for qualitative reliability. Materials and Methods: As a preclinical examination, this multiplex PCR was able to detect 1.25 × 103 copies/mL of 13 synthesized virus genomes and preserved same virus DNAs by the serial dilution method. Blood samples from 40 patients who underwent hematopoietic stem cell transplantation were then examined by multiplex PCR for 13 virus species, followed by quantitative real-time PCR for all 13 virus species as reference PCR when these patients developed symptoms suggestive of viral infection. Results: In 421 cumulative qualitative-quantitative tests, the multiplex PCR certainly detected 1.0 × 103 copies/mL of 5 viruses (CMV, JCV, BKV, hhV-6, ADV) that were frequently detected and thus reasonably analyzed. The positive and negative predictive values of multiplex PCR were 84.2% - 93.3% and 90.7% - 99.0%, respectively, and sensitivity and specificity were 59.0% - 83.3% and 97.2% - 99.2%, respectively, for these 5 viruses. Conclusion: From these performances, the multiplex PCR assay may be acceptable in a routine clinical laboratory setting.

关键词： Multiplex Virus PCR Assay Routine Laboratory Use Positive Predictive Value Negative Predictive Value Sensitivity Specificity

3种植物生长调节剂对薄叶鸡蛋参种子萌发的影响

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种子 2020年第7期39卷 77-80页

作者：靳祖石袁芳宋洪平孙秀丽西藏农牧学院西藏林芝860000

以薄叶鸡蛋参的种子为材料,研究不同消毒方法和植物生长调节剂对种子萌发和幼苗生长的影响。结果表明:1)种子最适消毒方法为75%乙醇1 min+3%h 2O 23 min。2)GA 3150 mg·L^-1、6-BA 5 mg·L^-1和NAA 2 mg·L^-1对种子萌发有显著的促进作... 详细信息

以薄叶鸡蛋参的种子为材料,研究不同消毒方法和植物生长调节剂对种子萌发和幼苗生长的影响。结果表明:1)种子最适消毒方法为75%乙醇1 min+3%h 2O 23 min。2)GA 3150 mg·L^-1、6-BA 5 mg·L^-1和NAA 2 mg·L^-1对种子萌发有显著的促进作用,其中用GA 3150 mg·L^-1浸种12 h的种子发芽指标最好,发芽率、发芽势、发芽指数和活力指数分别为92.06%、84.24%、9.12、12.46。3)GA 3150 mg·L^-1有利于增加幼苗的茎长和根长,6-BA 2~5 mg·L^-1有利于幼苗干物质的累积。

关键词：薄叶鸡蛋参消毒剂植物生长调节剂种子萌发幼苗生长

稳定过表达微小RNA-637对甲状腺癌细胞生物学行为的影响

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中华实验外科杂志 2018年第12期35卷 2226-2228页

作者：袁青领刘洋樊玉霞刘征王晓明贾勐耿祖仕卢秀波郑州大学第一附属医院甲状腺外科、河南省高等学校临床医学重点学科开放实验室 450052

目的观察过表达微小RNA(miRNA,miR)-637对甲状腺癌细胞TPC-1生物学行为的影响。方法采用慢病毒转染将过表达miR-637质粒(实验组)和空白质粒(阴性对照组)分别转入TPC-1细胞,通过细胞计数试剂盒(CCK-8)法观察细胞增殖情况,流式细胞仪分析... 详细信息

目的观察过表达微小RNA(miRNA,miR)-637对甲状腺癌细胞TPC-1生物学行为的影响。方法采用慢病毒转染将过表达miR-637质粒(实验组)和空白质粒(阴性对照组)分别转入TPC-1细胞,通过细胞计数试剂盒(CCK-8)法观察细胞增殖情况,流式细胞仪分析细胞凋亡率及周期分布,划痕实验和Transwell侵袭实验评价细胞迁移和侵袭能力。结果实验组TPC-1细胞生长曲线趋势较为平缓,细胞生长速度较阴性对照组显著降低(t=5.840,P=0.028)。与阴性对照组[(12.50±1.71)%]比较,实验组[(20.75±0.93)%]TPC-1细胞的凋亡率明显增加(t=19.674,P=0.003)。与阴性对照组细胞比较,实验组细胞在48h后S期下降至23.35%,G2/M期下降至17.58%。划痕实验及Transwell侵袭实验表明,与阴性对照组细胞比较,实验组的细胞迁移数明显减少(t=-26.186,P=0.001)。结论过表达miR-637能降低TPC-1细胞的增殖、凋亡、迁移和侵袭能力。

关键词：甲状腺癌微小RNA-637 增殖凋亡迁移侵袭