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Evaluation of the hepatoprotective and antioxidant effects of Tegillarca granosa flesh body extract against potassium bromide toxicity via targeting the histomorphometry,chromosomal and expressions of TGF-β1,VEGF and COX-2 genes in rats

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BIOCELL 2022年第1期46卷 219-234页

作者： ALI h.ABU ALMAATY BASMA M.hENDAM FAYEZ ALThOBAITI EMAN FAYAD yasmin M.ABD EL-AZIZ Department of Zoology Faculty of SciencePort Said UniversityPort Said42526Egypt Department of husbandry and Development of Animal Wealth Faculty of Veterinary MedicineMansoura UniversityMansoura35516Egypt Department of Biotechnology Faculty of ScienceTaif UniversityTaif21944Saudi Arabia

The hepatotoxic effect of potassium bromide(KBr)on rat liver tissues were determined,as well as the potential protective effect of Tegillaraca granosa(***)flesh body *** adult male albino rats were equally distributed into four groups;Group(I)treated with physiological saline(control group),Group(II)was orally gavaged by 200 mg/kg of *** body extract day after day,Group(III)was intoxicated by KBr(150 mg/kg bwt day after day orally)and finally,Group(IV)was given a combination of *** flesh body extract plus KBr with similar doses in the second and third *** the end of one month,blood,liver tissue and bone marrow samples were collected to be used for the required laboratory *** response to KBr toxicity,there was a significant increase in serum antioxidant biomarkers,which was accompanied by a significant change in hepatocyte ultrastructure and a significant change in carbohydrate and protein levels within the liver *** addition,KBr intoxication resulted in a substantial increase in the incidence of chromosomal aberrations such as holes,splits,deletions,fragments,ploidy,and ring chromosomes,as well as significant upregulation of TGF-1,VEGF,and COX-2 gene *** hepatotoxic effect of KBr was counteracted by treatment with *** flesh body *** flesh body extract has a curative antioxidant and numerous protective effects against KBr hepatotoxicity.

关键词： Potassium bromide Tegillarca granosa hepatic toxicity Antioxidant biomarker histomorphometry Chromosomal aberrations Gene expression

The potential of gene therapies for spinal cord injury repair:a systematic review and meta-analysis of pre-clinical studies

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Neural Regeneration Research 2023年第2期18卷 299-305页

作者： Catriona J.Cunningham Mindaugas Viskontas Krzysztof Janowicz yasmin Sani Malin Ehåkansson Anastasia heidari Wenlong huang Xuenong Bo Institute of Medical Sciences School of MedicineMedical Sciences&NutritionUniversity of AberdeenAberdeenUK Centre for Neuroscience Surgery and TraumaBlizard InstituteBarts and the London School of Medicine and DentistryQueen Mary University of LondonLondonUK

Currently,there is no cure for traumatic spinal co rd injury but one therapeutic approach showing promise is gene *** this systematic review and meta-analysis,we aim to assess the efficacy of gene therapies in pre-clinical models of spinal cord injury and the risk of *** this metaanalysis,registe red at PROSPERO(Registration ID:CRD42020185008),we identified relevant controlled in vivo studies published in English by searching the PubMed,Web of Science,and Embase *** restrictions of the year of publication were applied and the last literature search was conducted on August 3,*** then conducted a random-effects meta-analysis using the restricted maximum likelihood estimator.A total of 71 studies met our inclusion crite ria and were included in the systematic *** results showed that overall,gene therapies were associated with improvements in locomotor score(standardized mean difference[SMD]:2.07,95%confidence interval[CI]:1.68-2.47,Tau^(2)=2.13,I^(2)=83.6%)and axonal regrowth(SMD:2.78,95%CI:1.92-3.65,Tau^(2)=4.13,I^(2)=85.5%).There was significant asymmetry in the funnel plots of both outcome measures indicating the presence of publication *** used a modified CAMARADES(Collaborative Approach to M eta-Analysis and Review of Animal Data in Experimental Studies)checklist to assess the risk of bias,finding that the median score was 4(IQR:3-5).In particula r,reports of allocation concealment and sample size calculations were *** conclusion,gene therapies are showing promise as therapies for spinal co rd injury repair,but there is no consensus on which gene or genes should be targeted.

关键词： animal models gene delivery meta-analysis regenerative medicine spinal cord injury systematic review viral vectors

Genome constitution for Musa beccarii (Musaceae) varieties

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植物分类学报 2007年第1期45卷 69-74页

作者： Markku hKKINEN Chee how TEO yasmin Rofina OThMAN Botanic Garden University of Helsinki P. O. Box 44 (Jyrngntie 2) FI-00014 Finland Department of Biology University of Leicester University Road Leicester LE1 7RH United Kingdom Institute of Biological Sciences University of Malaya 50603 Kuala Lumpur Malaysia

Musa beccarii *** var. beccarii and Musa beccarii *** var. hottana h?kkinen were described earlier in Acta Phytotaxonomica et Geobotanica based on their morphological characteristics. In order to distinguish the genomes between the two M. beccarii varieties and M. coccinea Andrews, we have now studied them with the Inter- Retrotransposon Amplified Polymorphism (IRAP) marker analyses. The high levels of IRAP polymorphism detected in this study showed that M. beccarii var. beccarii and M. beccarii var. hottana are two distinct varieties. Additional IRAP bands found in M. beccarii var. beccarii indicated that M. beccarii var. hottana might be evolutionarily more ancient than M. beccarii var. beccarii because LTR retrotransposons are not transpositionally removed.

关键词： genome constitution inter-retrotransposon amplified polymorphism Musa beccarii var. beccarii Musa beccarii var. hottana Musa coccinea phylogenetic analysis.

Twenty-four-hour movement guidelines during middle adolescence and their association with glucose outcomes and type 2 diabetes mellitus in adulthood

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Journal of Sport and health Science 2023年第2期12卷 167-174页

作者： Antonio García-hermoso JoséFrancisco López-Gil yasmin Ezzatvar Robinson Ramírez-Vélez Mikel Izquierdo Navarrabiomed Hospital Universitario de Navarra(HUN)Universidad Publica de Navarra(UPNA)IdiSNAPamplona 31008Spain health and Social Research Center Universidad de Castilla-La ManchaCuenca 16007Spain Department of Nursing Universitat de ValenciaValencia 46010Spain

Purpose:The aim of the present study was to determine the association between adherence to the 24-h movement guidelines during middle adolescence and glucose outcomes(glycated hemoglobin and fasting glucose)and type 2 diabetes mellitus(T2DM)in adulthood,14 and 22 years ***:We analyzed data from apparently healthy adolescents aged 12-18 years who participated in WavesⅠandⅡ(1994-1996,n=14,738),WaveⅣ(2008-2009,n=8913),and Wave V(2016-2018,n=3457)of the National Longitudinal Study of Adolescent to Adult health(Add health)in the United *** activity,screen time,and sleep duration were measured using questionnaires,and the 24-h guidelines were defined as:5 or more times moderate-to-vigorous physical activity per week,≤2 h per day of screen time,and 9-11 h of sleep for 12-13 years and 8-10 h for 14-17 *** and venous whole blood was collected and analyzed to determine glycated hemoglobin and fasting glucose for WavesⅣandⅤ,***:Only 2.1%of the adolescents met all the 3 guidelines,and 37.8%met none of *** both wavesⅣandⅤ,adolescents who met physical activity and screen time guidelines had lower odds of T2DM in adulthood than those who did not meet any of these guidelines(WaveⅣ;prevalence ratio(PR)=0.57,95%confidence interval(95%CI):0.21-0.89;Wave V:PR=0.43,95%CI:0.32-0.74).Only for Wave V did adolescents who met all 3 guidelines have lower odds of T2DM at follow-up compared with those who did not meet any of these guidelines(PR=0.47,95%CI:0.24-0.91).Also,for each increase in meeting one of the 24-h recommendations,the odds of T2DM decreased by 18%(PR=0.82,95%CI:0.61-0.99)and 15%(PR=0.85,95%CI:0.65-0.98)in adulthood for WavesⅣandⅤ,***:Promoting all 24-h movement guidelines in adolescence,especially physical activity and screen time,is important for lowering the potential risk of T2DM in adulthood.

关键词： Glucose metabolism Glycated hemoglobin Physical activity Screen time Sleep duration

Purkait’s triangle revisited:role in sex and ancestry estimation

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Forensic Sciences Research 2022年第3期7卷 440-455页

作者： MennattAllah hassan Attia Mohamed hassan Attia yasmin Tarek Farghaly Bassam Ahmed El-Sayed Abulnoor Sotiris K.Manolis Ruma Purkait Douglas h.Ubelaker Forensic Medicine&Clinical Toxicology Department Faculty of MedicineAlexandria UniversityAlexandriaEgypt Institute for Intelligent Systems Research and Innovation Deakin UniversityVictoriaAustralia Biomedical Engineering Medical Research InstituteAlexandria UniversityAlexandriaEgypt Diagnostic Radiology Faculty of MedicineAlexandria UniversityAlexandriaEgypt Fixed Prosthodontics Faculty of DentistryFayoum UniversityFaiyumEgypt Animal&human Physiology Faculty of BiologyNational&Kapodistrian University of AthensAthensGreece Department of Anthropology University of AllahabadAllahabadIndia Department of Anthropology Smithsonian InstitutionWashingtonDCUS

Identification of unknown remains recovered from marine and terrestrial locations is a significant humanitarian *** investigation proposes a simple method applicable to fragmentary femora for a more refined level of ancestry and/or sex *** that end,we re-examined Purkait’s triangle which involves three inter-landmark distances between the traction epiphyses and the articular rim of femoral head.A large sample(n=584)from geographically diverse(Egyptian,Indian and Greek)populations was ***,shape(n=3)and trigonometrically derived variables and ratios(n=9 variables)were employed to detect any geographically-clustered morphological differences between these *** forest modelling(RFM)and linear discriminant function analysis(LDA)were employed to create classification models in instances where sex was known or *** sample was apportioned into training and test sets with a ratio 70/*** classification accuracies were evaluated by means of k fold cross-validation *** sex estimation,RFM showed similar performance to ***,RFM outperformed LDA in ancestry *** estimation was satisfactory in the Indian and Egyptian samples albeit the Greek sample was *** Greek samples presented greater morphological overlap with the Indian sample due to high within-group *** samples were accurately assigned to their ancestral category when sex was ***,higher classification accuracies in the validation sample were obtained in the sex-specific model of females than in *** RFM and the linear variables,the overall accuracy reached 83%which is distributed as 95%,71%and 86%for the Egyptian,Indian and Greek females,respectively;whereas in males,the overall accuracy is 72%and is distributed as 58%,87%and 50%for the Egyptian,Indian and Greek males,*** accuracies were also calculated per group in the test data using the 12 derived *** the f

关键词： Forensic sciences forensic anthropology Purkait’s triangle fragmentary femora ancestry estimation random forest modelling international forensic investigations

An overview of geological originated materials as a trend for adsorption in wastewater treatment

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Geoscience Frontiers 2022年第1期13卷 457-477页

作者： yasmin Vieira Matias Schadeck Netto Éder C.Lima Ioannis Anastopoulos Marcos L.S.Oliveira Guilherme L.Dotto Chemistry Department Federal University of Santa Maria-UFSM1000Roraima Avenue97105-900 Santa MariaRSBrazil Chemical Engineering Department Federal University of Santa Maria-UFSM1000Roraima Avenue97105-900 Santa MariaRSBrazil Institute of Chemistry Federal University of Rio Grande do Sul(UFRGS)P.O.Box 1500391501-970 Porto AlegreRSBrazil Department of Chemistry University of CyprusP.O.Box 20537CY-1678 NicosiaCyprus Universidad de Lima Avenida Javier Prado Este 4600-Santiago de Surco 1503Peru Department of Civil and Environmental Universidad de la CostaCalle 58#55-66080002 BarranquillaAtlánticoColombia

Adsorption is a unit operation widely used for the tertiary treatment of the most diverse effluents,whose mechanism is based on removing recalcitrant compounds from the organic and inorganic *** this process,choosing a suitable adsorbent is a fundamental *** review article focuses on the adsorbents with natural geological origin:minerals,clays,geopolymers,and even wastes resulted from mining ***,over 450 articles and research papers were *** materials’main sources are described,and their characteristics,composition,and intrinsic properties are related to ***,we discuss the effects of several process parameters,such as p h,temperature,pollutant,and adsorbent ***,equilibrium,kinetics,and thermodynamic aspects are also addressed,and relevant regeneration prospects and final ***,some suggestions and perspectives on applying these adsorbents in wastewater treatment are presented as future trends.

关键词： Adsorption Equilibrium Geological-based adsorbents Process parameters Wastewater treatment

Effect of Cerium Doping on Microstructure and Dielectric Properties of BaTiO_3 Ceramics

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Journal of Materials Science & Technology 2011年第8期27卷 759-763页

作者： Sabina yasmin Shamima Choudhury M.A. hakim A.h. Bhuiyan M.J. Rahman Department of Physics University of Dhaka Materials Science Division Atomic Energy Centre Department of Physics Bangladesh University of Engineering and Technology

A solid state reaction method was used to synthesize barium titanate （BT） and barium cerium titanate （BCT） ceramics at sintering temperature of 1473 K for 4 h. The effect of cerium （Ce） on the structure, microstructure and dielectric properties of BCT was investigated. The scanning electron microscopy （SEM） investigations revealed that the grain size increases with increasing Ce content. The X-ray diffraction （XI^D） patterns showed mostly the BT phase, where the lattice parameter decreased with the addition of Ce. The temperature dependence of dielectric constant showed decrease in the phase transition temperature with higher Ce content. The dielectric constant decreased slightly with increasing frequency. The direct current （dc） density-voltage characteristics of the ceramics showed ohmic behavior for both the BT and BCT. As the temperature increased, the dc resistivity of the ceramics decreased. The activation energy increased with increasing Ce content.

关键词： Cerium doped Ba1-xCexTiO3 Dielectric constant Current density

Peristaltic flow of Williamson fluid in a convected walls channel with Soret and Dufour effects

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International Journal of Biomathematics 2016年第1期9卷 223-241页

作者： T. hayat h. yasmin A. Alsaedt M. Ayub Department of MathematicsQuaid-I-Azam University 45320 Islamabad 44000 Pakistan Department of Mathematics Faculty of Science King Abdulaziz University Jeddah 21589 Saudi Arabia Department of MathematicsCOMSATS Institute of Information Technology G. T. Road Wah Cantt 47040 Pakistan

Peristaltic flow of magnetohydrodynamic (MhD) Williamson fluid in a symmetric channel is addressed. Modeling is given with Soret and Dufour effects. Channel walls have compliant properties. Analysis has been carried out through long wavelength and low Reynolds number approach. The obtained series solutions for small Weissenberg number are developed. Impact of variables reflecting the salient features of wall properties, Biot numbers and Soret and Dufour on the velocity, temperature and concentration has been point out. Trapping phenomenon is also analyzed.

关键词：磁流体蠕动通道对流雷诺兹数 MhD 长波长级数解

Effect of melting heat transfer on peristalsis in the presence of thermal radiation and Joule heating

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International Journal of Biomathematics 2015年第6期8卷 37-56页

作者： T. hayat Maimona Rafiq B. Ahmad h. yasmin Department of Mathematics Quaid-i-Azam University 45320 Islamabad 44000 Pakistan Department of MathematicsFaculty of Science King Abdulaziz University Jeddah 21589 Saudi Arabia Department of MathematicsCOMSATS Institute of Information Technology G. T. Road Wah Cantt 47040 Pakistan

Mathematical model is developed for peristaltic flow of viscous fluid through a compliant wall channel subject to melting heat transfer. Fluid is incompressible and magnetohydrodynamic. Analysis has been performed in the presence of Joule heating and thermal radiation. Solutions for small wave number are obtained. Physical quantities of interest are examined for various parameters of interest.

关键词：焦耳加热热辐射蠕动传热热作用熔融粘性流体数学模型