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Evolving role of adiponectin in cancer-controversies and update

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Cancer Biology & Medicine 2016年第1期13卷 101-119页

作者： Arnav Katira Peng h.tan UCL Medical School UCL Faculty of Medical Science University College London London WC1E 6BT UK Breast Unit Whittington Health London N19 5NF UK

Adiponectin(APN), an adipokine produced by adipocytes, has been shown to have a critical role in the pathogenesis of obesityassociated malignancies. Through its receptor interactions, APN may exert its anti-carcinogenic effects including regulating cell survival, apoptosis and metastasis via a plethora of signalling pathways. Despite the strong evidence supporting this notion, some work may indicate otherwise. Our review addresses all controversies critically. On the whole, hypoadiponectinaemia is associated with increased risk of several malignancies and poor prognosis. In addition, various genetic polymorphisms may predispose individuals to increased risk of obesity-associated malignancies. We also provide an updated summary on therapeutic interventions to increase APN levels that are of key interest in this field. To date efforts to manipulate APN levels have been promising, but much work remains to be done.

关键词： Adiponectin cancer therapeutic target

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Microstructural features of Ti-6Al-4V manufactured via high power laser directed energy deposition under low-cycle fatigue

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Journal of Materials Science & Technology 2021年第24期83卷 18-33页

作者： Y.M.Ren X.Lin h.O.Yang h.tan J.Chen Z.Y.Jian J.Q.Li W.D.huang School of Materials and Chemical Engineering Xi’an Technological UniversityXi’an710021China State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an710072China

Laser additive manufacturing(LAM)technique has unique advantages in producing geometrically complex metallic ***,the poor low-cycle fatigue property(LCF)of LAM parts restricts its widely ***,the microstructural features of a Ti-6 Al-4 V alloy manufactured via high power laser directed energy deposition subjected to low-cycle fatigue loading were *** fatigue loading,the microstructure of the as-deposited parts was found to exhibit a non-homogeneous distribution of columnar prior-βgrains(200-4000μm)at various scanning velocities(300-1500 mm/min)and relatively coarseα-laths(1.0-4.5μm).Under cyclic loading,fatigue microcracks typically initiated within the alignedαphases in the preferred orientation(45°to the loading direction)at the surface of the fatigue *** Ti-6 Al-4 V exhibited a single straight dislocation character at low strain amplitudes(tangled dislocations at high strain amplitudes(>1.1%).In addition,dislocation substructure features,such as dislocation walls,stacking faults,and dislocation networks,were also *** findings may provide opportunities to understand the fatigue failure mechanism of additive manufactured titanium parts.

关键词： Laser additive manufacturing Directed energy deposition Titanium alloy Low-cycle fatigue Microstructure

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研究胶树树冠和茎干关系的生物统计方法

热带作物译丛 1981年第3期 1-7页

作者： h.tan 周钟毓胡东琼

为了减轻真菌Microcylus ulei引起南美叶疫病造成的损失,首先在南美洲开始了三叶橡胶的树冠芽接试验。众所周知,马来西亚推广的高产无性系大多数易感该病。此外,其中一些无性系也易受风害和感染叶病、绯腐病以及回枯病等病害。为了克服... 详细信息

为了减轻真菌Microcylus ulei引起南美叶疫病造成的损失,首先在南美洲开始了三叶橡胶的树冠芽接试验。众所周知,马来西亚推广的高产无性系大多数易感该病。此外,其中一些无性系也易受风害和感染叶病、绯腐病以及回枯病等病害。为了克服这些缺陷,马来西亚橡胶研究院进行了一系列树冠芽接试验,自1948年开始第一个试验以来,已经得到大量试验资料。

关键词：树冠无性系橡胶无性繁殖系品系(育种) 弹性体茎干茎围配合力效应

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腐殖质的性质和分布

腐植酸 2010年第2期 28-35页

作者： Kim h.tan 张彩凤闫降凤段月娟美国佐治亚大学佐治亚州30301 中国腐植酸工业协会腐植酸质量检测中心太原030001 太原师范学院太原030012

从腐殖质的概念和历史背景开始,详细描述了它们的分布和分类。证据表明,腐殖质以特殊的组成和类型广泛地蕴藏在土壤、湿地、水生环境、地质矿床,以及农业、工业和城市垃圾之中。本文充分体现了化学领域的权威专家和相关学者在腐殖质方... 详细信息

从腐殖质的概念和历史背景开始,详细描述了它们的分布和分类。证据表明,腐殖质以特殊的组成和类型广泛地蕴藏在土壤、湿地、水生环境、地质矿床,以及农业、工业和城市垃圾之中。本文充分体现了化学领域的权威专家和相关学者在腐殖质方面的主要研究成果,旨在为广大读者提供一个腐殖质的基本概况。

关键词：腐殖质概念分布分类

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应用跳级小区品系试验区以缩短橡胶育种鉴定期的可能性

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热带农业科技 1981年第3期 67-71页

作者： h.tan S.h.ong M.O.Sultan S.K.Khoo 马来亚橡胶研究院

马来西亚橡胶研究院按常规育种方法鉴定新品系需30年以上的时间,现认为是不满意的。这里介绍一种缩短鉴定期的新方法,该方法是按苗圃苗木的产量和其他付性状进行予测选择,入选品系直接进入较大面积试验区,称为跳级小区品系试验区。这种... 详细信息

马来西亚橡胶研究院按常规育种方法鉴定新品系需30年以上的时间,现认为是不满意的。这里介绍一种缩短鉴定期的新方法,该方法是按苗圃苗木的产量和其他付性状进行予测选择,入选品系直接进入较大面积试验区,称为跳级小区品系试验区。这种方法至今认为是有希望的,已经有两个品系被选出,正在进一步鉴定,有可能早日推荐生产使用。

关键词：口口产量试验区小区初级系比橡胶弹性体

填料与弹性体间的互相作用(X) 填料-填料及填料-弹性体相互作用对橡胶补强性的影响

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橡胶参考资料 1994年第12期24卷 36-44页

作者： S.Wolff M.-J.Wang E.-h.tan 刘安祥

1 前言补强填料的表面特性对填料在橡胶中的补强性有最重要的影响,这种概念是人们通常能接受的观念。

关键词：填料弹性体橡胶补强性

Copper-catalyzed C–h bond functionalization enabled by programmed alternating current

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Science China Chemistry 2025年第1期 10-11页

作者： Zhoumei tan Kun Xu Chengchu Zeng Beijing Key Laboratory of Environmental and Viral Oncology College of Chemistry and Life Science Beijing University of Technology

Synthetic electrochemistry has been selected as one of the Top Ten Emerging Technologies in Chemistry in 2023 by International Union of Pure and Applied Chemistry (IUPAC)[1]. It has emerged as a sustainable platform for organic synthesis and has exhibited a wide range of applications from academia to industry [2]. however, electrosynthesis has been predominantly performed by using direct current (DC).

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棉花中抗性基因类似物的鉴定

国外作物育种 2004年第3期23卷 33-33页

作者： h.tan 向平

植物已经进化形成了抵抗病毒、细菌、真菌、线虫、原生动物和寄生物的遗传机制。许多病原抗性基因的鉴定增加了我们对植物抵抗病原侵染或缓慢感染以及病害扩展的了解。植物病原抗性基因编码能识别和结合由入侵病原无毒性基因编码产物的... 详细信息

植物已经进化形成了抵抗病毒、细菌、真菌、线虫、原生动物和寄生物的遗传机制。许多病原抗性基因的鉴定增加了我们对植物抵抗病原侵染或缓慢感染以及病害扩展的了解。植物病原抗性基因编码能识别和结合由入侵病原无毒性基因编码产物的蛋白质。认为这种识别和结合过程能引发信号级联。

关键词：棉花抗性基因类似物鉴定技术遗传机制

Magnetron sputtered nickel oxide with suppressed interfacial defect states for efficient inverted perovskite solar cells

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Journal of Energy Chemistry 2025年第1期100卷 348-355页

作者： Guoqiang Ma Qin tan Zhaoning Li Jingwei Xiu Jiafeng Wang Tianle Cheng Dong he Qiang Sun Xuhang Ma Francesco Lamberti Zhubing he Department of Materials Science and Engineering Institute of Innovative Materials (I2M) Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG)Southern University of Science and Technology (SUSTech) Core Research Facilities Southern University of Science and Technology Department of Chemical Sciences Department of Industrial Engineering University of Padova

Widely used spin-coated nickle oxide （NiOx） based perovskite solar cells often suffer from severe interfacial reactions between the NiOxand adjacent perovskite layers due to surface defect states,which inherently impair device performance in a long-term view,even with surface molecule *** this study,we developed high-quality magnetron-sputtered NiOxthin films through detailed process optimization,and compared systematically sputtered and spin-coated NiOxthin film surfaces from materials to *** sputtered NiOxfilms exhibit improved crystallinity,smoother surfaces,and significantly reduced Ni3+or Ni vacancies compared to their spin-coated ***,the interface between the perovskite and sputtered NiOxfilm shows a substantially reduced density of defect *** solar cells （PSCs） fabricated with our optimally sputtered NiOxfilms achieved a high power conversion efficiency （PCE） of up to 19.93%and demonstrated enhanced stability,maintaining 86.2% efficiency during 500 h of maximum power point tracking under one standard sun ***,with the surface modification using (4-(2,7-dibromo-9,9-dimethylacridin-10（9h）-yl)butyl)p hosphonic acid （DMAcPA）,the device PCE was further promoted to 23.07%,which is the highest value reported for sputtered NiOxbased PSCs so far.

关键词： Perovskite