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肝特异性对比剂钆塞酸是否会造成中枢神经系统T1WI信号长时间增加?一项基于91例病人的交叉研究

国际医学放射学杂志 2017年第3期 335-335页

作者： J.Kahn h.posch I.G.Steffen D.Geisel C.Bauknecht T.Liebig 时少杰 Departments of Radiation Medicine Campus Virchow-KlinikumCharité-Universittsmedizin Berlin

摘要目的评估反复给予肝脏特异性对比剂钆塞酸后,齿状核(DN)和苍白球(GP)与小脑中脚(MCP)、脑桥以及丘脑在T1WI上是否会有信号强度(SI)增加。材料与方法本研究是经机构伦理委员会批准的前瞻性横断面研究,参与者均签署知情同意书。采用1.... 详细信息

摘要目的评估反复给予肝脏特异性对比剂钆塞酸后,齿状核(DN)和苍白球(GP)与小脑中脚(MCP)、脑桥以及丘脑在T1WI上是否会有信号强度(SI)增加。材料与方法本研究是经机构伦理委员会批准的前瞻性横断面研究,参与者均签署知情同意书。采用1.5 T MRI连续收集病例组(91例,注射1～37剂量的钆塞酸)和对照组(52例,从未注射过钆类对比剂)的二维自旋回波T1WI影像。分别测量DN/MCP、DN-脑桥、GP-丘脑、GP-脑脊髓液的SI比,并采用非参数KruskalWallis检验、相应的配对检验和Spearman秩相关进行统计分

关键词：对比剂 SI 丘脑间脑特异性 T1WI 桥脑脑桥用药次数 MCP 中位数

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Utilizing neural networks to supplant chemical kinetics tabulation through mass conservation and weighting of species depletion

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Energy and AI 2024年第2期16卷 101-110页

作者： Franz M.Rohrhofer Stefan posch Clemens Gößnitzer JoséM.García-Oliver Bernhard C.Geiger Know-Center Gmbh Sandgasse 36Graz8010StyriaAustria LEC Gmbh Inffeldgasse 19Graz8010StyriaAustria Universitat Politècnica de València Camíde VeraValència46022ValènciaSpain

Artificial Neural Networks(ANNs)have emerged as a powerful tool in combustion simulations to replace memory-intensive tabulation of integrated chemical *** reaction mechanisms,however,present a challenge for standard ANN approaches as modeling multiple species typically suffers from inaccurate predictions on minor *** paper presents a novel ANN approach which can be applied on complex reaction mechanisms in tabular data form,and only involves training a single ANN for a complete reaction *** approach incorporates a network architecture that automatically conserves mass and employs a particular loss weighting based on species *** modifications are used to improve the overall ANN performance and individual prediction accuracies,especially for minor species mass *** validate its effectiveness,the approach is compared to standard ANNs in terms of performance and ANN *** distinct reaction mechanisms(h_(2),C_(7)h_(16),C_(12)h_(26),OME_(34))are used as a test cases,and results demonstrate that considerable improvements can be achieved by applying both modifications.

关键词： Neural network approach Chemical kinetics Flamelet tabulation Mass conservation Species loss weighting

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A probe into the acid deposition mitigation path in China over the last four decades and beyond

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National Science Review 2024年第4期11卷 84-92页

作者： Qian Yu Xiaodong Ge haotian Zheng Jia Xing Lei Duan Dongwei Lv Dian Ding Zhaoxin Dong Yisheng Sun posch Maximilian Danni Xie Yu Zhao Bin Zhao Shuxiao Wang Jan Mulder Thorj?rn Larssen Jiming hao State Key Laboratory of Environmental Simulation and Pollution Control School of EnvironmentTsinghua University State Key Laboratory of Pollution Control &Resource Reuse and School of the Environment Nanjing University State Environmental Protection Key Laboratory of Sources and Control of Air Pollution Complex School of EnvironmentTsinghua University International Institute for Applied System Analysis(IIASA) School of Land Engineering Chang'an University Faculty of Environmental Sciences and Natural Resource Management Norwegian University of Life Sciences Norwegian Institute for Water Research

China currently has the highest acid deposition globally, yet research on its status, impacts, causes and controls is lacking. here, we compiled data and calculated critical loads regarding acid deposition. The results showed that the abatement measures in China have achieved a sharp decline in the emissions of acidifying pollutants and a continuous recovery of precipitation p h, despite the drastic growth in the economy and energy consumption. however, the risk of ecological acidification and eutrophication showed no significant decrease. With similar emission reductions, the decline in areas at risk of acidification in China(7.0%) lags behind those in Europe(20%) or the USA(15%). This was because, unlike Europe and the USA, China's abatement strategies primarily target air quality improvement rather than mitigating ecological impacts. Given that the area with the risk of eutrophication induced by nitrogen deposition remained at 13%of the country even under the scenario of achieving the dual targets of air quality and carbon dioxide mitigation in 2035, we explored an enhanced ammonia abatement pathway. With a further 27% reduction in ammonia by 2035, China could largely eliminate the impacts of acid deposition. This research serves as a valuable reference for China's future acid deposition control and for other nations facing similar challenges.

关键词： acid deposition critical loads acidification eutrophication ammonia abatement

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