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ON ThE gAUSSIAN KINEMATIC FORMULA OF *** AND ***

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Acta Mathematica Scientia 2025年第1期45卷 200-214页

作者： Joseph h.g.Fu Department of Mathematics University of GeorgiaAthensGA30602USA

We apply methods of algebraic integral geometry to prove a special case of the gaussian kinematic formula of *** idea,suggested already by Adler and Taylor,is to view the gKF as the limit of spherical kinematic formul... 详细信息

关键词： integral geometry kinematic formula probability density gaussian density

Altered microRNA composition in the uterine lumen fluid in cattle(Bos taurus)pregnancies initiated by artificial insemination or transfer of an in vitro produced embryo

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Journal of Animal Science and Biotechnology 2025年第1期16卷 76-91页

作者： Fernando h.Biase Sarah E.Moorey Julie g.Schnuelle Soren Rodning Martha Sofia Ortega Thomas E.Spencer School of Animal Sciences Virginia Polytechnic Institute and State University175 W Campus DrBlacksburgVA 24061USA Department of Animal Science University of TennesseeKnoxvilleTN 37996USA Department of Clinical Sciences Auburn UniversityAuburnAL 36849USA Department of Animal Science Auburn UniversityAuburnAL 36849USA Department of Animal and Dairy Sciences University of Wisconsin MadisonMadisonWI 53706USA Division of Animal Sciences University of MissouriColumbiaMO 65211USA

Background MicroRNAs(miRNAs)are presented in the uterine lumen of many mammals,and in vitro experiments have determined that several miRNAs are important for the regulation of endometrial and trophoblast *** aim was to identify and contrast the miRNAs present in extracellular vesicles(EVs)in the uterine lumen fluid(ULF)at the onset of attachment in cattle pregnancies(gestation d 18)initiated by artificial insemination(AI)or by the trans-fer of an in vitro-produced blastocyst(IVP-ET).A third group had no conceptus after the transfer of an IVP *** The abundance of 263 annotated miRNAs was quantified in the EVs collected from *** was an increase in the transcript abundance of 20 miRNAs in the ULF EVs from the AI pregnant group,while 4 miRNAs had a lower abundance relative to the group not containing a ***,4 miRNAs were more abun-dant in ULF EVs in the AI pregnant group relative to IVP-ET group(bta-mir-17,bta-mir-7-3,MIR7-1,MIR18A).Specific miRNAs in the ULF EVs were co-expressed with messenger RNAs expressed in extra-embryonic tissues and endome-trium,including genes that are known to be their *** The results provide biological insights into the participation of miRNAs in the regulation of trophoblast proliferation and differentiation,as well as in endometrium *** knowledge that in vitro cultured embryos can contribute to the altered abundance of specific miRNAs in the uterine lumen can lead to the development of cor-rective approaches to reduce conceptus losses during the first month of pregnancy in cattle.

关键词： Artificial reproductive technology Cattle Conceptus Embryos Endometrium Small RNA

[Effects of adipose stem cell-derived exosomes on rat tendon healing and its impact on the periphery neuropeptides expression]

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Zhonghua yi xue za zhi 2025年第7期105卷 544-553页

作者： h T Xu h Zhang K Shen h Zhou h h Song D M guo X Y gu g L Wang Q Wang g Y Yin Department of Orthopedics the First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China. School of Biological Science and Medical Engineering Southeast University Nanjing 210000 China.

To investigate the effect of injectable adipose tissue stem cell-derived exosome-encapsulated hydrogel on the tendon healing in rats and to evaluate the temporal and spatial expressions of periphery neuropeptides at healing site. To generate the injectable exosome-encapsulated hydrogel, the methacryloylchloride solution (gelMA) and the photoinitiator were mixed first, then the exosome solution was added and oscillated together. Followed with exposing in the ultraviolet light in a wave length 405 nm for 30 seconds to form an injectable hydrogel. The Sprague Dawley (SD) rats were performed with full thickness transection and surgical repair administration of Achilles tendon to establish the animal model, including 4 groups: intact control (C group, selected the contralateral side of tendon transection with surgical repair group), tendon transection with surgical repair group (S group), tendon transection with surgical repair and hydrogel implantation group (h group) and tendon transection with surgical repair and exosome-encapsulated hydrogel group (E group). The samples were harvested on Day 7, 14 and 28 after the operation, respectively. histopathological examination was performed with hematoxylin-eosin staining (hE staining) and immunohistochemistry staining of tenogenesis marker (Tenomodulin, TNMD), periphery neuropeptide markers (growth associated protein-43, gAP43; S100 calcium-binding protein B, S100B; neuropeptide Y, NPY; calcitonin gene-related peptide, CgRP; Substance P, SP). Morphological property was characterized with tendon length, cross-sectional area (CSA), and gastrocnemius weight ratio. Biomechanical testing was measured with maximum failure load, stiffness and tensile modulus. The results of the quantitative polymerase chain reaction (qPCR) showed that the expression level of the TNMD gene in the E group was 2.12±0.43, which was significantly higher than that in the h group (1.26±0.28) and the S group (1.21±0.39) (both he immunoh

关键词：肌腱脂肪干细胞外泌体可注射水凝胶肌腱愈合外周神经肽

Seasonal influence on miRNA expression dynamics of extracellular vesicles in equine follicular fluid

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Journal of Animal Science and Biotechnology 2025年第1期16卷 136-152页

作者： Jean M.Feugang Ahmed gad Nico g.Menjivar ghassan M.Ishak Samuel gebremedhn Melba O.gastal Notsile h.Dlamini Radek Prochazka Eduardo L.gastal Dawit Tesfaye Department of Animal and Dairy Sciences Mississippi State UniversityMississippi StateMS 39762USA Animal Reproduction and Biotechnology Laboratory(ARBL) Department of Biomedical SciencesCollege of Veterinary Medicine and Biomedical SciencesColorado State UniversityFort CollinsCO 80523USA Department of Animal Production Faculty of AgricultureCairo UniversityGiza 12613Egypt Department of Surgery and Obstetrics College of Veterinary MedicineUniversity of BaghdadBaghdad 10011Iraq Animal Science School of Agricultural SciencesSouthern Illinois UniversityCarbondaleIL 62901USA J.R.Simplot Company KunaID 83634USA Institute of Animal Physiology and genetics Czech Academy of SciencesLiběchov 27721Czech Republic

Background Ovarian follicular fluid(FF)is a dynamic environment that changes with the seasons,affecting follicle development,ovulation,and oocyte *** in the follicles release tiny particles called extracellular vesicles(EVs)containing vital regulatory molecules,such as microRNAs(miRNAs).These miRNAs are pivotal in facilitating commu-nication within the follicles through diverse signaling and information transfer ***-coupled miRNA signaling is implicated to be associated with ovarian function,follicle and oocyte growth and response to various environmen-tal ***,we investigated how seasonal variations directly influence the ovulatory and anovulatory states of ovarian follicles and how are they associated with follicular fluid EV-coupled miRNA dynamics in *** Ultrasonographic monitoring and follicular fluid aspiration of preovulatory follicles in horses during the ano-vulatory(spring:non-breeding)and ovulatory(spring,summer,and fall:breeding)seasons and subsequent EV isola-tion and miRNA profiling identified significant variation in EV-miRNA cargo *** identified 97 miRNAs with dif-ferential expression among the groups and specific clusters of miRNAs involved in the spring transition(miR-149,-200b,-206,-221,-328,and-615)and peak breeding period(including miR-143,-192,-451,-302b,-100,and let-7c).Bioinformatic analyses showed enrichments in various biological functions,e.g.,transcription factor activity,transcrip-tion and transcription regulation,nucleic acid binding,sequence-specific DNA binding,p53 signaling,and post-trans-lational *** analyses revealed distinct sets of significantly up-and down-regulated miRNAs associ-ated with spring anovulatory(Cluster 1)and summer ovulation–the peak breeding season(Clusters 4 and 6).Conclusions The findings from the current study shed light on the dynamics of FF-EV-coupled miRNAs in relation to equine ovulatory and anovulatory seasons,and their roles in understanding the

关键词： Extracellular vesicle Follicle growth Follicular fluid horse Mare Ovulation Pre-ovulation Seasonal breeding

Two texture zeros for Dirac neutrinos in a diagonal charged lepton basis

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Chinese Physics C 2025年第1期49卷 127-138页

作者： Yessica Lenis John D.gómez William A.Ponce Richard h.Benavides Instituto de Física Universidad de AntioquiaA.A.1226MedellínColombia Instituto Tecnológico Metropolitano Facultad de Ciencias Exactas y AplicadasCalle 73 N°76-354 via el voladorMedellínColombia

A systematic study of the neutrino mass matrix M_(v) with two texture zeros in a basis that the charged leptons are diagonal,and under the assumption that neutrinos are Dirac particles is *** study is conducted without any approximation,first analytically and then *** neutrino oscillation data is used in our *** implications of M_(v) on lepton CP violation and neutrino mass spectrum are explored.

关键词： neutrinos texture zeros Dirac particles

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina hromada Patrick heimel Markus Kerbl Lászlógál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.heinzel Antal Nógrádi Andreas h.Teuschl-Woller David hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNgCs). however, the use of tNgCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNgC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNgCs and compared the various features of these improved silk^(+) tNgCs with the tubes without holes(silk^(–) tNgCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNgCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNgCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNgCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNgCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

城市污水污染物排放量和污水集中收集率的计算

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环境工程学报 2025年第02期 259-268页

作者：曹业始丁永伟 KROISS h 高闯闯 VANLOOSDREChT M DAIggER g T 中持水务股份有限公司研发分公司苏州市排水有限公司维也纳工业大学水质和资源管理研究所代尔夫特理工大学生物技术系密歇根大学土木和环境工程系

城市污水集中收集率是城市污水系统运行效率的关键指标，城市污水污染物排放量是计算城市污水集中收集率的必需参数，但城市污水系统较高溢流量和缺乏溢流监测带来计算城市污水排污量的困扰。为此，应用城市污水系统模型和用水、污水处... 详细信息

城市污水集中收集率是城市污水系统运行效率的关键指标，城市污水污染物排放量是计算城市污水集中收集率的必需参数，但城市污水系统较高溢流量和缺乏溢流监测带来计算城市污水排污量的困扰。为此，应用城市污水系统模型和用水、污水处理、常住人口数等常规市政数据，首次提出了根据污水处理厂进水流量和负荷计算城市污水污染物排放量和污水集中收集率的2种方法。以面积约110 km2、常住居民近100×10～4人口的城区污水系统为例，展示了应用2种方法的所需数据、具体步骤和计算结果，分析了2种方法各自的适用性。对流动人口、工商业活动和人日排污量等因素对城市污水污染物排污量的影响和估算进行了讨论。2种方法对当下国内和国外一些国家的城市污水排污量、污水集中收集率的计算和城市污水系统运行效率的评估，具有现实意义。

关键词：城市污水排污量污水集中收集率污水溢流污水处理厂城市污水系统城市水环境

Plant-substrate biochar properties critical for mediating reductive debromination of 1,2-dibromoethane

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Journal of Environmental Sciences 2025年第1期147卷 1-10页

作者： Jonathan h.Lindhardt Peter E.holm Yong-guan Zhu Changyong Lu hans Christian B.hansen Department of Plant and Environmental Sciences Faculty of ScienceUniversity of CopenhagenThorvaldsensvej 401871 Frederiksberg CDenmark Key lab of Urban Environment and health Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China Sino-Danish Center for education and research China and DenmarkDalgas Avenue 4DK-8000 Aarhus C.Denmark

Dibromoethane is a widespread,persistent organic *** are known mediators of reductive dehalogenation by layered Fe^(Ⅱ)-Fe^(Ⅲ)hydroxides(green rust),which can reduce 1,2-dibromoethane to innocuous bromide and ***,the critical characteristics that determine mediator functionality are lesser *** biochar substrates were pyrolyzed at 600℃and 800℃,characterized by elemental analysis,X-ray photo spectrometry C and N surface speciation,X-ray powder diffraction,specific surface area analysis,and tested for mediation of reductive debromination of 1,2-dibromoethane by a green rust reductant under anoxic conditions.A statistical analysis was performed to determine the biochar properties,critical for debromination kinetics and total debromination *** was shown that selected plant based biochars can mediate debromination of 1,2-dibromoethane,that the highest first order rate constant was 0.082/hr,and the highest debromination extent was 27%in reactivity experiments with 0.1μmol(20μmol/L)1,2-dibromoethane,≈22 mmol/L Fe^(Ⅱ)gR,and 0.12 g/L soybean meal biochar(7 days).Contents of Ni,Zn,N,and P,and the relative contribution of quinone surface functional groups were significantly(ph 1,2-dibromoethane debromination,while adsorption,specific surface area,and the relative contribution of pyridinic N oxide surface groups were significantly negatively correlated with debromination.

关键词： Environmental remediation Biochar Persistent organic pollutants(POPs) Environmental catalysis green rust

Technology Progress Report for Spaceborne Microwave Remote Sensing

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空间科学学报 2006年第Z1期26卷 71-75页

作者： jhang Jingshan LIU heguang DONg Xiaolong Center for Space Science and Applied Research Chinese Academy of Sciences Beijing 100080 China Center for Space Science and Applied Research Chinese Academy of Sciences Beijing 100080 China Center for Space Science and Applied Research Chinese Academy of Sciences Beijing 100080 China

In this presentation, technological progress for China's microwave remote sensing is introduced. New developments of the microwave remote sensing instruments formeteorological satellite FY-3, ocean dynamic measurement satellite (hY-2), environment small SAR satellite (h J-1C) and China's lunar exploration satellite (Chang'E-1), are reported.

关键词： Microwave Remote Sensing