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Chinese Journal of Chemical Engineering 2019年第5期27卷 1171-1176页

作者： Lijuan Shen Xu Yan Lei Nie Wenyan Xu Shiwei Miao haibin Wang h.Fai Poon haibin Qu Pharmaceutical Informatics Institute College of Pharmaceutical ScienceZhejiang UniversityHangzhou 310058China Zhejiang hisun Pharmaceutical Co. Ltd.FuyangHangzhou 311404China

A deeper understanding of the biological events occurring when bioprocess parameters changed will be of great value in improving the monoclonal antibodies (mAbs) production. Design of experiment (DoE) was applied to investigate the effect of process parameters (ph, temperature shift and dissolve oxygen (DO)) on protein titer. The key metabolites connecting the critical process parameters (CPPs) with monoclonal antibody production were identified by different chemometrics tools. Finally, the biological events of marker metabolites relating with titer improvement were concluded. ph and temperature shift were identified as CPPs that affect the target protein titer. A series of metabolites influenced by the altered CPPs and correlated with protein titer were screened by principal component analysis (PCA) and Pearson' correlation test. The marker metabolites and their pathways linking CPPs to target protein titer in different culture phases were summarized. Metabolomics and chemometrics are promising data-driven tools to shine light into the biological black box between the bioprocess parameters and process performance.

关键词： Canonical metabolites Chemometrics Critical process parameters Metabolomics Protein titer

Rapid building damage assessment system using mobile phone technology

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Earthquake Engineering and Engineering Vibration 2014年第3期13卷 519-533页

作者： G.P.Cimellaro G.Scura C.S.Renschler A.M.Reinhorn h.U.Kim Department of Structural & Geotechnical Engineering (DISTR) Politecnico di Torino Corso Ducadegli Abruzzi 24 10129 Turin Italy Department of Geography University at Buffalo 116 Wilkeson Quad Amherst NY 14261 USA Department of Civil Structural and Environmental Engineering University at Buffalo Buffalo NY 14260-4300 USA College of Politics and Economics Kyung Hee University Seoul 130-701 Korea

One common scenario during disasters such as earthquakes is that the activity of damage field reconnaissance on site is not well-coordinated. For example in Italy the damage assessment of structures after an earthquake is managed from the Italian Emergency Authority, using printed forms （AeDES） which are filled by experts on site generating a lot of confusion in filling and transferring the forms to the Disaster Management Operative Center. Because of this, the paper explores the viability of using mobile communication technologies （smart phones） and the Web to develop response systems that would aid communities after a major disaster, providing channels for allowing residents and responders ofuploading and distributing information, related to structural damages coordinating the damage field reconnaissance. A mobile application that can be run by residents on smart phones has been developed, to give an initial damage evaluation of the area, which is going to be very useful when resources （e.g. the number of experts is limited）. The mobile application has been tested for the first time during 2012 Emilia earthquake to enhance the emergency response, showing the efficiency of the proposed method in statistical terms comparing the proposed procedure with the standard procedure.

关键词： resilience damage assessment smart phones field reconnaissance emergency management system community resilience disaster recovery

Modeling of numerical simulation and experimental verification for carburizing-nitriding quenching process

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中国有色金属学会会刊：英文版 2006年第B02期16卷 566-571页

作者： R. MUKAI T. MATSUMOTO JU Dong-ying T. SUZUKI h. SAITO Y. ITO high-Tech Research Center Special Researcher Saitama Institute of Technology Fukaya 369-0293 Japan Department of Mechanical Engineering Saitama Institute of Technology Fukaya 369-0293 Japan Research Center of high Technology Anshan University of Science and Technology Anshan 114044 China Department of Technology Development Tobuyakin Ltd. Japan

A model considering quantitative effects of diffused carbon and nitrogen gradients and kinetics of phase transformation is presented to examine metallo-thermo-mechanical behavior during carburized and nitrided quenching. Coupled simulation of diffusion, phase transformation and stress/strain provides the final distribution of carbon and nitrogen contents as well as residual stress and distortion. Effects of both transformation and lattice expansion induced by carbon and nitrogen absorption were introduced into calculating the evolution of the internal stress and strain. In order to verify the method and the results, the simulated distributions of carbon and nitrogen content and residual stress/strain of a ring model during carburized and nitrided quenching were compared with the measured data.

关键词：金属热处理渗碳渗氮淬火过程数值模拟模型实验验证

Who should you be following? The top 100 social media influencers in orthopaedic surgery

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World Journal of Orthopedics 2019年第9期10卷 327-338页

作者： Nathan h Varady Akash A Chandawarkar Willem A Kernkamp Itai Gans Department of Orthopaedic Surgery Massachusetts General Hospital/Harvard Medical SchoolBostonMA 02114United States Department of Plastic and Reconstructive Surgery Johns Hopkins University School of MedicineBaltimoreMD 21205United States Department of Orthopaedic Surgery Johns Hopkins University School of MedicineBaltimoreMD 21205United States

BACKGROUND Social media has been credited with the potential to transform medicine,and Twitter was recently named“an essential tool”for the academic *** this,peer-to-peer and educational influence on social media has not been studied within orthopaedic *** knowledge is important to identify who is controlling the conversation about orthopaedics to the *** hypothesized that the plurality of top influencers would be sports medicine surgeons,that social media influence would not be disconnected from academic productivity,and that some of the top social media influencers in orthopaedic surgery would not be orthopaedic *** To identify the top 100 social media influencers within orthopaedics,characterize who they are,and relate their social media influence to academic *** Twitter influence scores for the topic“orthopaedics”were collected in July 2018 using Right Relevance *** accounts with the top influence scores were linked to individual names,and the account owners were characterized with respect to specialty,subspecialty,practice setting,location,board certification,and academic hirsch index(h-index).RESULTS Seventy-eight percent of top influencers were orthopaedic *** most common locations included California(13%),Florida(8%),New York(7%),United Kingdom(7%),Colorado(6%),and Minnesota(6%).The mean academic h-index of the top influencers(n=79)was 13.67±4.12(mean±95%CI)and median 7(range 1-89)(median reported h-index of academic orthopaedic faculty is 5 and orthopaedic chairpersons is 13).Of the 78 orthopaedic surgeons,the most common subspecialties were sports medicine(54%),hand and upper extremity(18%),and spine(8%).Most influencers worked in private practice(53%),followed by academics(17%),privademics(14%),and hospital-based(9%).All eligible orthopaedic surgeons with publicly-verifiable board certification statuses were board-certified(n=74).CONCLUSION The top orthopaedic social media influencers on

关键词： Social media Influence Impact Twitter Orthopaedics Orthopedics

Investigation of Water Stability of Concrete Wastes in Asphalt Treated Base

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武汉理工大学学报 2010年第17期32卷 59-61页

作者： WEI W ChEN M Z WU S P JIANG h Key Laboratory of Silicate Materals Science and Engineering Wuhan University of TechnologyWuhan 430070China

The use of concrete wastes in asphalt treated base (ATB) not only prevents environmental pollution but also protect stone resources. But the strength of the concrete wastes is often weaker than nature aggregates and the binding properties with asphalt is poor. So it difficult to meet the requirements of asphalt treated base. In this paper,The organosilicone waterproofing material is used to improve the performance of concrete wastes and the long term immersing frozen-thaw cycle test were used to investigate the anti-stripping performance of limestone asphalt mixture,concrete wastes asphalt mixture and concrete wastes asphalt mixture having treated by organosilicone waterproofing material. The experimental results show that organosilicone waterproofing material can improve the water stability of asphalt mixture. The use of concrete wastes in ATB is achievable.

关键词： concrete wastes organosilicone waterproofing material water stability asphalt treated base

Photodissociation of sodium iodide and resonant ionization of sodium atom produced

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原子与分子物理学报 2004年第1期21卷 1-3页

作者： hUOBing-hai Z.T.Salim A.h.Bakery SchoolofScicnce TianjinUniversityTianjin300072P.R.China DepartmentofPhysics SwanseaUniversitySwanseaPA866U.K.

Resonant ionization spectroscopy (RIS) and resonant ionization mass spectroscopy (RIMS) are employed to detect the photodissociation product of sodium iodide molecules in a molecular beam in an intense laser field in the absence of the buffer gases. Time of flight mass spectra is recorded. In particular, the appearances of multiphoton ionization are discussed.

关键词：光致离解碘化钠分子钠原子共振电离光谱激光辐射双色共振电离

Ion population fraction calculations using improved screened hydrogenic model with l-splitting

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Chinese Physics B 2018年第10期27卷 424-432页

作者： Amjad Ali G Shabbir Naz Rukhsana Kouser Ghazala Tasneem M Saleem Shahzad Aman-ur-Rehman M h Nasim Department of Physics and Applied Mathematics Pakistan Institute of Engineeringand Applied Sciences Department of Nuclear Engineering Pakistan Institute of Engineeringand Applied Sciences

Ion population fraction（IPF） calculations are very important to understand the radiative spectrum emitted from the hot dense matter. IPF calculations require detailed knowledge of all the ions and correlation interactions between the electrons of an ion which are present in a plasma environment. The average atom models, e.g., screened hydrogenic model with l-splitting（ShML）, now have the capabilities for such calculations and are becoming more popular for in line plasma calculations. In our previous work [Ali A, Shabbir Naz G, Shahzad M S, Kouser R, Rehman A and Nasim M h 2018 high Energy Density Phys. 26 48], we have improved the continuum lowering model and included the exchange and correlation effects in ShML. This study presents the calculation of IPF using classical theory of fluctuation for our improved screened hydrogenic model with l-splitting（I-ShML） under local thermodynamic equilibrium conditions for iron and aluminum plasma over a wide range of densities and temperatures. We have compared our results with other models and have found a very good agreement among them.

关键词： self-consistent average atom model average ionization state ion population

Reticulate spore ornamentation in Strobilomyces

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菌物学报 2011年第6期30卷 901-911页

作者： Ronald h.Petersen John Dunlap Karen W.hughes Department of Ecology and Evolutionary Biology University of TennesseeKnoxvilleTN 37996-1100USA Electron Microscope Facility Division of BiologyUniversity of TennesseeKnoxvilleTN 37996-0830USA

Reticulate spore ornamentation in Strobilomyces(Boletaceae,Basidiomycotina) is visible under light microscopy(bright field and phase contrast) up to 1,500×.While some distinctions can be made at this magnification,ontogeny and fine structure of the ornamentation cannot be *** electron microscope images,conversely,reveal significant additional structure from which the ontogenetic process can be *** numerous New and Old World collections,this paper presents evidence distinguishing reticulate ornamentation ontogeny in these disjunct populations.

关键词：网状孢子电子显微镜观察菌物学

The impact of reporting frequency on the information quality of share price： evidence from Chinese state-owned enterprises

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Frontiers of Business Research in China 2018年第2期12卷 83-100页

作者： Yin Toa Lee Wilson h. S. Tong Ernst & Young 22/F CITIC Tower 1 Tim Mei Avenue Central Hong Kong Hong Kong

As a major global exchange, the Stock Exchange of hong Kong （SEhK） only requires semi-annual reporting whereas other major exchanges including the ones in Chinese mainland require quarterly reporting. We argue against the traditional view that higher reporting frequency is necessarily more beneficial. The decision on reporting frequency depends on how the information is being processed by the recipient traders and the results are not obvious. Using a sample of Chinese companies dual- listed in both China A share market and SEhK （Ah shares） as the experimental group and mainland＇s companies listed on SEhK （h shares） only as the control group, we apply the difference-in-difference （DID） method to investigate the impacts of reporting frequency on stock information quality. The results suggest that after China A share market require quarterly financial reporting for all listed companies in 2002, the information asymmetry of the h tranche of Ah stocks increases. Different from prior studies, the results suggest a negative association between stock information quality and financial reporting frequency. We argue that the increased information asymmetry in the h tranche is caused by the noise spilled over from the A tranche. We conduct multivariable GARCh tests and find evidence supporting this conjecture.

关键词： Mainland market hong Kong market Dual-listing Reporting frequency,Information asymmetry Volatility spillover effects

激光诱导聚酰亚胺纳米微结构中分子链取向排列的研究

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高等学校化学学报 1999年第10期20卷 1642-1645页

作者：路庆华 h.hiraoka 王宗光上海交通大学化学化工学院上海200240 香港科技大学化学系

通过Ｎｄ∶ＹＡＧ偏振脉冲激光辐射聚酰亚胺薄膜，在其表面制得大面积纳米级周期性微线条，线条的周期性为２００ｎｍ，线条方向始终平行于偏振激光束电场方向，线条横截面为圆形或椭圆形柱状结构．采用偏振反射红外光谱分别在... 详细信息

通过Ｎｄ∶ＹＡＧ偏振脉冲激光辐射聚酰亚胺薄膜，在其表面制得大面积纳米级周期性微线条，线条的周期性为２００ｎｍ，线条方向始终平行于偏振激光束电场方向，线条横截面为圆形或椭圆形柱状结构．采用偏振反射红外光谱分别在平行与垂直纳米线条的方向上测试聚合物表面分子ＩＲ吸收光谱，结果发现，１７２２和１２３１ｃｍ－１处的吸收有明显的二向色性，表明微线条内聚合物分子链部分呈现取向排列，

关键词：聚酰亚胺分子取向排列纳米微结构激光诱导