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In situ TEM investigation of electron irradiation and aging-induced high-density nanoprecipitates in an Mg-10Gd-3Y-1Zn-0.5Zr alloy

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Journal of Magnesium and Alloys 2024年第5期12卷 1841-1853页

作者： M.Lv h.L.Ge Q.Q.Jin X.h.Shao Y.T.Zhou B.Zhang X.L.Ma Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences School of Materials Science and Engineering University of Science and Technology of China Materials Science and Engineering Research Center Guangxi University of Science and Technology

In-situ electron irradiation and aging are applied to introduce high-density precipitates in an Mg-10Gd-3Y-1Zn-0.5Zr(GWZ1031K, wt.%)alloy to improve the hardness. The results show that the hardness of the Mg alloy after irradiation for 10 h and aging for 9 h at 250 ℃ is 1.64 GPa, which is approximately 64% higher than that of the samples before being treated. It is mainly attributed to γ' precipitates on the basal plane after irradiation and the high-density nanoscale β' precipitates on the prismatic plane after aging, which should be closely related to the irradiation-induced homogenous clusters. The latter plays a key role in precipitation hardening. This result paves a way to improve the mechanical properties of metallic materials by tailoring the precipitation through irradiation and aging.

关键词： Mg alloy Electron beam irradiation hardening Precipitates In-situ TEM

Network Embedding Algorithm for Vulnerability Assessment of Power Transmission Lines Using Integrated Structure and Attribute Information

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 351-360页

作者： Xianglong Lian Tong Qian Zepeng Li Xingyu Chen Wenhu Tang Q.h.Wu School of Electric Power Engineering South China University of TechnologyGuangzhou 510640China

In power systems,failures of vulnerable lines can trigger large-scale cascading failures,and vulnerability assessment is dedicated to locating these lines and reducing the risks of such failures.Based on a structure and attribute network embedding(SANE)algorithm,a novel quantitative vulnerability analysis method is proposed to identify vulnerable lines in this research.First,a two-layered random walk network with topological and electrical properties of transmission lines is established.Subsequently,based on the weighted degree of nodes in the two-layered network,the inter-layer and intra-layer walking transition probabilities are developed to obtain walk sequences.Then,a Word2Vec algorithm is applied to obtain lowdimension vectors representing transmission lines,according to obtained walk sequences for calculating the vulnerability index of transmissions lines.Finally,the proposed method is compared with three widely used methods in two test systems.Results show the network embedding based method is superior to those comparison methods and can provide guidance for identifying vulnerable lines.

关键词： Network embedding random walk transmission lines vulnerability assessment

CD8+T cell metabolic flexibility elicited by CD28-ARS2 axisdriven alternative splicing of PKM supports antitumor immunity

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Cellular & Molecular Immunology 2024年第3期21卷 260-274页

作者： G.Aaron holling Colin A.Chavel Anand P.Sharda Mackenzie M.Lieberman Caitlin M.James Shivana M.Lightman Jason h.Tong Guanxi Qiao Tiffany R.Emmons Thejaswini Giridharan Shengqi hou Andrew M.Intlekofer Richard M.higashi Teresa W.M.Fan Andrew N.Lane Kevin h.Eng Brahm h.Segal Elizabeth A.Repasky Kelvin P.Lee Scott h.Olejniczak Department of Immunology Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Department of Medicine Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA human Oncology and Pathogenesis Program Memorial Sloan Kettering Cancer CenterNew YorkNY 10065USA Center for Environmental Systems Biochemistry Department of Toxicology and Cancer Biology and Markey Cancer CenterLexingtonKY 40536USA Department of Cancer Genetics and Genomics Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Present address:University of Colorado Boulder BoulderCO 80309USA Present address:Dana Farber Cancer Institute BostonMA 02215USA Present address:Massachusetts Institute of Technology BostonMA 02139USA Present address:Melvin and Bren Simon Comprehensive Cancer Center Indiana University School of MedicineIndianapolisIN 46202USA

Metabolic flexibility has emerged as a critical determinant of CD8+T-cell antitumor activity,yet the mechanisms driving the metabolic flexibility of T cells have not been determined.In this study,we investigated the influence of the nuclear cap-binding complex(CBC)adaptor protein ARS2 on mature T cells.In doing so,we discovered a novel signaling axis that endows activated CD8+T cells with flexibility of glucose catabolism.ARS2 upregulation driven by CD28 signaling reinforced splicing factor recruitment to pre-mRNAs and affected approximately one-third of T-cell activation-induced alternative splicing events.Among these effects,the CD28-ARS2 axis suppressed the expression of the M1 isoform of pyruvate kinase in favor of PKM2,a key determinant of CD8+T-cell glucose utilization,interferon gamma production,and antitumor effector function.Importantly,PKM alternative splicing occurred independently of CD28-driven PI3K pathway activation,revealing a novel means by which costimulation reprograms glucose metabolism in CD8+T cells.

关键词： Immunometabolism mRNA splicing CD8 T cells ARS2 PKM2

Long Term X-Ray Spectral Variations of the Seyfert-1 Galaxy Mrk 279

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Research in Astronomy and Astrophysics 2024年第6期24卷 309-316页

作者： K.Akhila Ranjeev Misra Savithri h.Ezhikode K.Jeena Department of Physics Providence Women's College University of Calicut Inter-University Centre for Astronomy and Astrophysics (IUCAA) Department of Physics and Electronics CHRIST (Deemed to be University)

We present the results from a long term X-ray analysis of Mrk 279 during the period 2018–2020. We use data from multiple missions–AstroSat, NuSTAR and XMM-Newton, for the purpose. The X-ray spectrum can be modeled as a double Comptonization along with the presence of neutral Fe Kα line emission, at all epochs. We determined the source’s X-ray flux and luminosity at these different epochs. We find significant variations in the source’s flux state. We also investigate the variations in the source’s spectral components during the observation period. We find that the photon index and hence the spectral shape follow the variations only over longer time periods. We probe the correlations between fluxes of different bands and their photon indices, and found no significant correlations between the parameters.

关键词： galaxies: individual (Mrk 335) galaxies: Seyfert X-rays: galaxies

Editorial for the Special Issue on Emerging Technology and Advanced Application of Nondestructive Detection for Power Equipment

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Chinese Journal of Electrical Engineering 2024年第1期10卷 1-2页

作者： Li J. Mei h. Li S. Tianjin University China Tsinghua Shenzhen International Graduate School China Lanzhou Jiaotong University China

The rapid development of clean and renewable energy technologies represented by wind and solar energy,as well as the continuous growth of load demand,have put forward higher requirements for the safe operation of the power equipment.The performance of power equipment based on traditional dielectric materials is often limited by various defects generated during molding,transportation,assembly,and operation,which cannot meet the reliability requirements of power systems in the new situation.Nondestructive detection is an essential technical method in industrial development,which can detect and evaluate the defect and damage status of in-service equipment,key components,and materials without damaging the object.

关键词： service Application operation

Search for production of dark fermion candidates in association with heavy neutral gauge boson decaying to dimuon in proton-proton collisions at√s=8 TeV using CMS open data

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Chinese Physics C 2024年第4期48卷 6-13页

作者： Y.Mahmoud h.Abdallah M.T.hussein S.Elgammal Centre for theoretical physics The British University in EgyptEgypt Physics Department Faculty of ScienceCairo UniversityEgypt

In this study,we conducted a search for dark matter using a part of the data recorded by the CMS experiment during run-I of the LhC in 2012 with a center of mass energy of 8 TeV and an integrated luminosity of 11.6 fb−1.These data were gathered from the CMS open data.Dark matter,in the framework of the simplified model(mono-Z′),can be produced from proton-proton collisions in association with a new hypothetical gauge boson,Z′.Thus,the search was conducted in the dimuon plus large missing transverse momentum channel.One benchmark scenario of mono-Z′,which is known as light vector,was used for interpreting the CMS open data.No evidence of dark matter was observed,and exclusion limits were set on the masses of dark matter and Z′at 95%confidence level.

关键词： dark matter large hadron collider CMS open data search for new physics dark fermion

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Trauma to the solid abdominal organs:The missed dark box of colonoscopy

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World Journal of Gastroenterology 2024年第7期30卷 624-630页

作者： Mohamed h Emara Usama Mazid Yasmine A Elshaer Mahmoud A Elkerdawy Dilaver Farooq Malik Aya M Mahros Department of hepatology Gastroenterologyand Infectious DiseasesKafrelsheikh UniversityKafr-Elshikh 33516Egypt Department of Medicine Alyousif HospitalAlkhobar 31952Saudi Arabia

Colonoscopy is an integral part of the lower bowel care and is generally considered a potentially safe diagnostic and therapeutic procedure performed as a daycare outpatient procedure.Colonoscopy is associated with different complications that are not limited to adverse events related to the bowel preparation solutions used,the sedatives used,but to the procedure related as well including bleeding and perforation.Injuries to the extra-luminal abdominal organs during colonoscopy are uncommon,however,serious complications related to the procedure have been reported infrequently in the literature.Life threatening injuries to the spleen,liver,pancreas,mesentery,and urinary bladder have been reported as early as in mid-1970s.These injuries should not be overlooked by clinicians and endoscopists.Steadily increasing abdominal pain,abdominal distension,and hemodynamic instability in absence of rectal bleeding should raise the possibility of severe organ injury.Splenic and hepatic injury following colonoscopy are usually serious and may be life threatening.Although conservative management may help,yet they usually need interventional radiology or surgical intervention.Acute pancreatitis following colonoscopy is usually mild and is mostly managed conservatively.The mechanism of abdominal organ injuries during colonoscopy is not fully understood,however many risk factors have been identified,which can be classified as-organ related,procedure related,and local abdominal factors.Difficult colonoscopy and prior intra-abdominal adhesions are probably the most relevant risk factors for these injuries.Left lateral position,avoidance of looping and excessive force during the procedure would probably reduce the risk of such injuries.

关键词： Colonoscopy Pancreatitis Trauma Complications Adhesions

Prediction of vertical displacement for a buried pipeline subjected to normal fault using a hybrid FEM-ANN approach

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Frontiers of Structural and Civil Engineering 2024年第3期18卷 428-443页

作者： hedye JALALI Reza YEGANEh KhAKSAR Danial MOhAMMADZADEh S. Nader KARBALLAEEZADEh Amir h.GANDOMI Department of Civil Engineering Architecture and UrbanismSadjad University of TechnologyPO Box ***MashhadIran Department of Civil Engineering Faculty of EngineeringEqbal Lahoori Institute of Higher EducationPO Box ***MashhadIran Faculty of Civil Engineering Architectureand ArtScience and Research Branch of Islamic Azad UniversityPO Box ***TehranIran Faculty of Engineering&Information Technology University of Technology SydneyUltimoNSW 2007Australia University Research and Innovation Center(EKIK) Óbuda UniversityBudapest 1034Hungary

Fault movement during earthquakes is a geotechnical phenomenon threatening buried pipelines and with the potential to cause severe damage to critical infrastructures.Therefore,effective prediction of pipe displacement is crucial for preventive management strategies.This study aims to develop a fast,hybrid model for predicting vertical displacement of pipe networks when they experience faulting.In this study,the complex behavior of soil and a buried pipeline system subjected to a normal fault is analyzed by using an artificial neural network(ANN)to generate predictions the behavior of the soil when different parameters of it are changed.For this purpose,a finite element model is developed for a pipeline subjected to normal fault displacements.The data bank used for training the ANN includes all the critical soil parameters(cohesion,internal friction angle,Young’s modulus,and faulting).Furthermore,a mathematical formula is presented,based on biases and weights of the ANN model.Experimental results show that the maximum error of the presented formula is 2.03%,which makes the proposed technique efficiently predict the vertical displacement of buried pipelines and hence,helps to optimize the upcoming pipeline projects.

关键词： buried pipelines normal Fault finite element method multilayer perceptron neural network formulation

hybrid robust fault detection and isolation of satellite reaction wheel actuators

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Journal of Control and Decision 2024年第1期11卷 117-131页

作者： h.Abbasi Nozari S.J.Sadati Rostami Paolo Castaldi Silvio Simani Faculty of Electrical and Computer Engineering Babol Noshirvani University of TechnologyBabolIran Department of Electrical Electronic and Information EngineeringUniversity of BolognaCesenaItaly Department of Engineering University of FerraraFerraraItaly

In this paper,a combined robust fault detection and isolation scheme is studied for satellite system subject to actuator faults,external disturbances,and parametric uncertainties.The proposed methodology incorporates a residual generation module,including a bank of filters,into an intelligent residual evaluation module.First,residual filters are designed based on an improved nonlinear differential algebraic approach so that they are not affected by external disturbances.The residual evaluation module is developed based on the suggested series and parallel forms.Further,a new ensemble classification scheme defined as blended learning integrates heterogeneous classifiers to enhance the performance.A wide range of simulations is carried out in a high-fidelity satellite simulator subject to the constant and time-varying actuator faults in the presence of disturbances,manoeuvres,uncertainties,and noises.The obtained results demonstrate the effectiveness of the proposed robust fault detection and isolation method compared to the traditional nonlinear differential algebraic approach.

关键词： Robust fault detection and isolation reaction wheels blended learning series and parallel fault detection and isolation forms satellite attitude control system