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Surface-mounted bender elements for measuring horizontal shear wave velocity of soils

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第11期9卷 1490-1496页

作者： Yan-guo ZhOU Yun-min ChEN Yoshiharu ASAKA Tohru abe MOE Key Laboratory of Soft Soils and Geoenvironmental Engineering Zhejiang University Hangzhou 310027 China Institute of Geotechnical Engineering Zhejiang University Hangzhou 310027 China Institute of Technology Shimizu Corporation Tokyo 135-8530 Japan

The bender element testing features its in-plane directivity, which allows using bender elements to measure the shear wave velocities in a wider range of in-plane configurations besides the standard tip-to-tip alignment. This paper proposed a novel bender element testing technique for measuring the horizontal shear wave velocity of soils, where the bender elements are surface- mounted and the axes of the source and receiver elements are parallel to each other. The preliminary tests performed on model ground of silica sand showed that, by properly determining the travel distance and time of the shear waves, the surface-mounted bender elements can perform as accurately as the conventional "tip-to-tip" configuration. Potentially, the present system provides a promising nondestructive tool for characterizing geomaterials and site conditions both in laboratory and in the fields.

关键词： Bender elements Shear wave velocity Model test Nondestructive evaluation Surface-mounted Sand

Preparation and characterization of tea tree oil-β-cyclodextrin microcapsules with super-high encapsulation efficiency

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Journal of Bioresources and Bioproducts 2023年第3期8卷 224-234页

作者： Peifu Kong Junichi Peter abe Shunsuke Masuo Toshiharu Enomae Degree Programs in Life and Earth Sciences University of TsukubaIbaraki 305-8572Japan Faculty of Life and Environmental Sciences University of TsukubaIbaraki305-8572Japan

This study aimed to prepare tea tree oil-β-cyclodextrin microcapsules using an optimized co-precipitated *** impact of the volume fraction of ethanol in the solvent system for microencapsulation on encapsulation efficiency was investigated and analyzed ***-high encapsulation efficiency was achieved when a 40%volume fraction of ethanol was used for the microencapsulation procedure,where the recovery yield of microcapsules and the embedding fraction of tea tree oil in microcapsules were as high as 88.3%and 94.3%,***,considering the operation cost,including time and energy consumption,an economical preparation was validated so that it would be viable for large-scale *** on the results of morphological and X-ray diffraction analysis,the crystal structure appeared to differ before and after *** results of gas chromatography-mass spectrometry and Fourier transform infrared spectroscopy confirmed the successful formation of ***,the antibacterial activity of the fabricated microcapsules was assessed by a simple growth inhibition test using Bacillus subtilis as the study object,and the hydrophilic property was proved by a water contact angle measurement.

关键词： β-cyclodextrin Co-precipitation Encapsulation efficiency Microcapsule Tea tree oil

BRAF inhibitor:a novel therapy for ameloblastoma in mandible

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Chinese Journal of Cancer Research 2018年第6期30卷 677-678页

作者： Masanobu abe Liang Zong Takahiro abe hideyuki Takeshima Jiafu Ji Toshikazu Ushijima Kazuto hoshi Department of Oral & Maxillofacial Surgery University of Tokyo Hospital Division for health Service Promotion University of Tokyo Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Center of Gastrointestinal SurgeryPeking University Cancer Hospital & Institute Graduate School of Medicine University of Tokyo Division of Epigenomics National Cancer Center Research Institute

Ameloblastoma is a benign but locally aggressive odontogenic neoplasm that accounts for 10% of all tumors arising in the mandible and maxilla (1). Eighty percent of ameloblastomas arise in the mandible, and they are u... 详细信息

关键词： BRAF inhibitor:a novel therapy for ameloblastoma in mandible

Zn Dissolution-Passivation Behavior with ZnO Formation via In Situ Characterizations

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Energy & Environmental Materials 2024年第1期7卷 193-200页

作者： Tanyanyu Wang Masahiro Kunimoto Masahiro Yanagisawa Masayuki Morita Takeshi abe Takayuki homma Graduate School of Advanced Science and Engineering Waseda University1-104 TotsukamachiShinjuku-kuTokyo 169-8050Japan Office of Society-Academia Collaboration for Innovation Kyoto UniversityGokashoUji 611-0011Japan Graduate School of Engineering Kyoto UniversityKyoto daigaku-katsuraNishikyo-kuKyoto 615-8510Japan

In this study,ZnO formation during the dissolution-passivation process of Zn anodes is observed via in situ Raman and optical *** Zn passivation during galvanostatic anodization merely follows the dissolution-precipitation model,whereas that of potentiodynamic polarization exhibits different behaviors in different potential ***,the Zn electrode is gradually covered by a ZnO precipitation film and then undergoes solid-state oxidation at~255 *** starting point of solid-state oxidation is well indicated by the abrupt current drop and yellow coloration of the electrode *** the pseudo passivation,an intense current oscillation is ***,blink-like color changes between yellow and dark blue are revealed for the first time,implying that the oscillation is caused by the dynamic adsorption and desorption of Oh *** as-formed ZnOs then experience a dissolution-reformation evolution,during which the crystallinity of the primary ZnO film is improved but the solid-state-formed ZnO layer becomes rich in oxygen ***,oxide densification is realized,contributing to the Zn *** study provides new insights into the Zn dissolution-passivation behavior,which is critical for the future optimization of Zn batteries.

关键词： in situ characterization Zn dissolution and passivation ZnO formation

Oxidative modification of free-standing amino acids by Fe(Ⅱ)/αKG-dependent oxygenases

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Engineering Microbiology 2023年第1期3卷 56-64页

作者： hui Tao Ikuro abe Graduate School of Pharmaceutical Sciences The University of TokyoTokyoJapan Collaborative Research Institute for Innovative Microbiology The University of TokyoTokyoJapan

Fe(Ⅱ)/α-ketoglutarate(αKG)-dependent oxygenases catalyze the oxidative modification of various molecules,from DNA,RNA,and proteins to primary and secondary *** also catalyze a variety of biochemical reactions,including hydroxylation,halogenation,desaturation,epoxidation,cyclization,peroxidation,epimeriza-tion,and *** the versatile catalytic capability of such oxygenases,numerous studies have been conducted to characterize their functions and elucidate their structure-function relationships over the past few *** acids,particularly nonproteinogenic amino acids,are considered as important building blocks for chemical synthesis and components for natural product *** addition,the Fe(Ⅱ)/αKG-dependent oxy-genase superfamily includes important enzymes for generating amino acid derivatives,as they efficiently modify various free-standing amino *** recent discovery of new Fe(Ⅱ)/αKG-dependent oxygenases and the repur-posing of known enzymes in this superfamily have promoted the generation of useful amino acid ***,this study will focus on the recent progress achieved from 2019 to 2022 to provide a clear view of the mechanism by which these enzymes have expanded the repertoire of free amino acid oxidative modifications.

关键词： Fe(II)/αKG-dependent oxygenases Amino acids Enzyme

Current overview on the genetic basis of key genes involved in soybean domestication

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aBIOTECh 2022年第2期3卷 126-139页

作者： Sijia Lu Chao Fang Jun abe Fanjiang Kong Baohui Liu Innovative Center of Molecular Genetics and Evolution School of Life SciencesGuangzhou UniversityGuangzhou 510006China Guangzhou Key Laboratory of Crop Gene Editing Guangzhou UniversityGuangzhou 510006China Research Faculty of Agriculture Hokkaido UniversitySapporoHokkaido 060-0808Japan

Modern crops were created through the domestication and genetic introgression of wild relatives and adaptive differentiation in new *** the domestication-related genes and unveiling their molecular diversity provide clues for understanding how the domesticated variants were selected by ancient people,elucidating how and where these crops were *** genetics and genomics have explored some domestication-related genes in soybean(Glycine max).here,we summarize recent studies about the quantitative trait locus(QTL)and genes involved in the domestication traits,introduce the functions of these genes,clarify which alleles of domesticated genes were selected during domestication.A deeper understanding of soybean domestication could help to break the bottleneck of modern breeding by highlighting unused genetic diversity not selected in the original domestication process,as well as highlighting promising new avenues for the identification and research of important agronomic traits among different crop species.

关键词： Soybean Domestication Diversity Gene

Involvement of Cbl-b-mediated macrophage inactivation in insulin resistance

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World Journal of Diabetes 2017年第3期8卷 97-103页

作者： Tomoki abe Katsuya hirasaka Takeshi Nikawa Department of Nutritional Physiology Institute of Biomedical Sciences Tokushima University Graduate School Graduate School of Fisheries Science and Environmental Studies Nagasaki University

Aging and overnutrition cause obesity in rodents and humans. It is well-known that obesity causes various diseases by producing insulin resistance(IR). Macrophages infiltrate the adipose tissue(AT) of obese individuals and cause chronic low-level inflammation associated with IR. Macrophage infiltration is regulated by the chemokines that are released from hypertrophied adipocytes and the immune cells in AT. Saturated fatty acids are recognized by toll-like receptor 4(TLR4) and induce inflammatory responses in AT macrophages(ATMs). The inflammatory cytokines that are released from activated ATMs promote IR in peripheral organs, such as the liver, skeletal muscle and AT. Therefore, ATM activation is a therapeutic target for IR in obesity. The ubiquitin ligase Casitas b-lineage lymphoma-b(Cbl-b) appears to potently suppress macrophage migration and activation. Cbl-b is highly expressed in leukocytes and negatively regulates signals associated with migration and activation. Cbl-b deficiency enhances ATM accumulation and IR in aging- and diet-induced obese mice. Cbl-b inhibits migration-related signals and SFA-induced TLR4 signaling in ATMs. Thus, targeting Cbl-b may be a potential therapeutic strategy to reduce the IR induced by ATM activation. In this review, we summarize the regulatory functions of Cbl-b in ATMs.

关键词： Casitas b-lineage lymphoma-b Insulin resistance Macrophage Obesity Toll-like receptor 4

Identifying potential field sites for production of cellulosic energy plants in Asia

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International Journal of Agricultural and Biological Engineering 2014年第3期7卷 59-67页

作者： Nobuhito Sekiya Taiichiro hattori Fumitaka Shiotsu Jun abe Shigenori Morita Institute for Sustainable Agro-ecosystem Services Graduate School of Agricultural and Life SciencesThe University of TokyoTokyo 188-0002Japan NARO Kyushu Okinawa Agricultural Research Center Kagoshima 891-3102Japan College of Agriculture Ibaraki UniversityInashikiIbaraki 300-0393Japan Department of Plant Science School of AgricultureTokai UniversityKumamoto 869-1404Japan Faculty of Agriculture Tokyo University of AgricultureKanagawa 243-0034Japan

Cellulosic bioethanol produced from non-edible plants avoids food-fuel *** such plants on marginal non-arable lands also avoids the use of *** this study,attempts were made to identify potential field sites for cellulosic bioethanol production in *** this study,GIS databases containing information about requirements such as land use,landform,and climate were *** with terrestrial constraints were then removed from the candidate field sites using a terrain slope *** remaining lands were evaluated using a net primary production(NPP)*** these areas,southern and eastern India,northeastern Thailand,and southern Sumatra(Indonesia)had high *** the 2nd phase,local information regarding infrastructure,and agriculture were ***-establishment feasibility was high for eastern India and southern *** field sites were then located in satellite images of these two *** the 3rd phase,soils around potential sites were *** residents were interviewed to estimate the cost of producing plants for biomass *** selected using this simple method are suitable for biomass production.

关键词： bioethanol biomass cellulosic energy plants geographic information system unused land

Chronic hepatitis C virus infection and lipoprotein metabolism

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World Journal of Gastroenterology 2015年第36期21卷 10299-10313页

作者： Yoshio Aizawa Nobuyoshi Seki Tomohisa Nagano hiroshi abe Department of Internal Medicine The Jikei University Katsushika Medical Center

hepatitis C virus(hCV) is a hepatotrophic virus and a major cause of chronic liver disease,including hepatocellular carcinoma,worldwide. The life cycle of hCV is closely associated with the metabolism of lipids and lipoproteins. The main function of lipoproteins is transporting lipids throughout the body. Triglycerides,free cholesterol,cholesteryl esters,and phospholipids are the major components of the transported lipids. The pathway of hCV assembly and secretion is closely linked to lipoprotein production and secretion,and the infectivity of hCV particles largely depends on the interaction of lipoproteins. Moreover,hCV entry into hepatocytes is strongly influenced by lipoproteins. The key lipoprotein molecules mediating these interactions are apolipoproteins. Apolipoproteins are amphipathic proteins on the surface of a lipoprotein particle,which help stabilize lipoprotein structure. They perform a key role in lipoprotein metabolism by serving as receptor ligands,enzyme co-factors,and lipid transport carriers. Understanding the association between the life cycle of hCV and lipoprotein metabolism is important because each step of the life cycle of hCV that is associated with lipoprotein metabolism is a potential target for anti-hCV therapy. In this article,we first concisely review the nature of lipoprotein and its metabolism to better understand the complicated interaction of hCV with lipoprotein. Then,we review the outline of the processes of hCV assembly,secretion,and entry into hepatocytes,focusing on the association with lipoproteins. Finally,we discuss the clinical aspects of disturbed lipid/lipoprotein metabolism and the significance of dyslipoproteinemia in chronic hCV infection with regard to abnormal apolipoproteins.

关键词： hepatitis C virus Apolipoprotein Lipo-viral partic