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Free vibration and buckling analysis of polymeric composite beams reinforced by functionally graded bamboo fbers

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Applied math.matics and mech.nics(English.Edition) 2024年第3期45卷 543-562页

作者： h.m.FEIZABAD m.h.YAS Department of mech.nical Engineering Razi UniversityKermanshah ***Iran

Natural fibers h.ve been extensively research.d as reinforcement materials in polymers on account of th.ir environmental and economic advantages in comparison with.synth.tic fibers in th. recent *** fibers are renowned for th.ir good mech.nical properties,abundance,and sh.rt cycle *** beams are one of th. fundamental structural components and are susceptible to mech.nical loads in engineering applications,th.s paper performs a study on th. free vibration and buckling responses of bamboo fiber reinforced composite(BFRC)beams on th. elastic *** different functionally graded(FG)layouts and a uniform one are th. considered distributions for unidirectional long bamboo fibers across th. *** elastic properties of th. composite are determined with.th. law of *** h.milton’s principle,th. governing equations of motion are *** generalized differential quadrature meth.d(GDQm)is th.n applied to th. equations to obtain th. *** ach.eved outcomes exh.bit th.t th. natural frequency and buckling load values vary as th. fiber volume fractions and distributions,elastic foundation stiffness values,and boundary conditions(BCs)and slenderness ratio of th. beam ***,a comparative study is conducted between th. derived analysis outcomes for BFRC and h.mogenous polymer beams to examine th. effectiveness of bamboo fibers as reinforcement materials,demonstrating th. significant enh.ncements in both.vibration and buckling responses,with.th. exception of natural frequencies for cantilever beams on th. Pasternak foundation with.th. FG-◇fiber ***,th. obtained analysis results of BFRC beams are also compared with.th.se for carbon nanotube reinforced composite(CNTRC)beams found in th. literature,indicating th.t th. buckling loads and natural frequencies of BFRC beams are lower th.n th.se of CNTRC beams.

关键词： bamboo fiber free vibration buckling analysis functionally graded(FG)beam elastic foundation generalized differential quadrature meth.d(GDQm)

Response Evaluation Using Contrast-Enh.nced Ultrasound for Unresectable Advanced h.patocellular Carcinoma Treated With.Tyrosine Kinase Inh.bitors Plus Anti-PD-1 Antibody Th.rapy

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Editorial for th. Special Issue on Emerging Tech.ology and Advanced Application of Nondestructive Detection for Power Equipment

Ultrasound in medicine and Biology 2024年第1期50卷 142-149页

作者： Zh.o C.-K. Guan X. Pu Y.-Y. Zh.u B.-Y. Wang L.-F. Sun Y.-K. Yin h.-h. Xia h.-S. Wang X. h.n h. Xu h.-X. Department of Ultrasound Zhongshan Hospital Institute of Ultrasound in Medicine and Engineering Fudan University Shanghai China Sh.ngh.i Institute of medical Imaging Shanghai China Central Laboratory and Department of medical Ultrasound Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital University of Electronic Science and Technology of China Chengdu China

Objective: Th. aim of th. work described h.re was to evaluate th. role of contrast-enh.nced ultrasound (CEUS) in response evaluation for unresectable advanced h.patocellular carcinoma (h.C) treated with.tyrosine kinase inh.bitors (TKIs) plus anti-programmed cell death.protein-1 (PD-1) antibody th.rapy. meth.ds: A prospective coh.rt of consecutive patients with.h.C wh. received combined TKI/anti-PD-1 antibody treatment for unresectable h.C between January 2022 and October 2022 was included in th.s study. Th. patients underwent unenh.nced ultrasound (US) and CEUS examinations before treatment and at follow-up. Ch.nges in th. largest diameters of th. target tumor on unenh.nced US and th. largest diameters of th. enh.ncing target tumors on CEUS were evaluated. Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 with.unenh.nced US and magnetic resonance imaging/computed tomograph. (mRI/CT) and modified RECIST (mRECIST) with.CEUS and CEmRI/CT were used to assess treatment response. Results: A total of 24 h.C patients (23 men and 1 woman; mean age: 56.5 ± 8.5 y; Barcelona Clinic Liver Cancer stage C, 62.5%; 29 intrah.patic target tumors) were studied. Calculations of degree of necrosis in th. target tumors revealed no significant differences between CEUS and CEmRI/CT (44.5 ± 36.2% vs. 45.3 ± 36.8%, p = 0.862). As for th. differentiation of responders from non-responders, th. agreement between RECIST version 1.1 of unenh.nced US and mRECIST-CEUS was poor (κ coefficient = 0.233). meanwh.le, th.re was a h.gh.degree of concordance between mRECIST-CEUS and mRECIST-CEmRI/CT (κ coefficient = 0.812). Conclusion: CEUS proved to be superior to baseline US and is comparable to CEmRI/CT in defining treatment outcome for combined TKI/anti-PD-1 antibody th.rapy. © 2023 World Federation for Ultrasound in medicine & Biology

关键词： Anti-angiogenic th.rapy Anti-PD-1 antibody Contrast-enh.nced ultrasound h.patocellular carcinoma

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Ch.nese Journal of Electrical Engineering 2024年第1期10卷 1-2页

作者： Li J. mei h. Li S. Tianjin University China Tsingh.a Sh.nzh.n International Graduate Sch.ol China Lanzh.u Jiaotong University China

Th. rapid development of clean and renewable energy tech.ologies represented by wind and solar energy,as well as th. continuous growth.of load demand,h.ve put forward h.gh.r requirements for th. safe operation of th. power *** performance of power equipment based on traditional dielectric materials is often limited by various defects generated during molding,transportation,assembly,and operation,wh.ch.cannot meet th. reliability requirements of power systems in th. new *** detection is an essential tech.ical meth.d in industrial development,wh.ch.can detect and evaluate th. defect and damage status of in-service equipment,key components,and materials with.ut damaging th. object.

关键词： service Application operation

DFT investigation of h.lf-metallic ferromagnetic rare earth.based spinels mgh._(2)Z_(4)(Z=S,Se)

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Journal of Rare Earth. 2024年第1期42卷 121-128,I0005页

作者： maiza Zanib mumtaz manzoor N.A.Noor m.Waqas Iqbal mazia Asgh.r h.h.h.gazy A.Laref Department of Ph.sics Riphah International UniversityLahore CampusPakistan Research.Centre for Advanced materials Science King Khalid UniversityP.O.Box 9004AbhaSaudi Arabia Department of Ph.sics Faculty of ScienceKing Khalid UniversityP.O.Box 9004AbhaSaudi Arabia Department of Ph.sics and Astronomy College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

h.lf-metallic ferromagnetism,mech.nical as well as th.rmoelectric properties for rare earth.based spinels mgh._(2)Z_(4)(Z=S,Se)were investigated using density functional th.ory(DFT).Structural optimization was done with.Perdew-Burke-Eh.enzorf(PBE)sol-generalized gradient approximation(GGA)to calculate th. lattice constant of both.spinels comparable to experimental *** addition,Born stability criteria and negative formation energy sh.w th.t our studied spinels are also structurally and dynamically stable in th. cubic *** ferromagnetic(Fm)state stability,we also calculated th. energy differences among Fm,antiferromagnetic(AFm),and non-magnetic(Nm)***,Curie temperatures of ferromagnetic ph.ses were also *** used Trans-Blah. improved BeckeJoh.son(TB-mBJ)potential functional for electronics as well as magnetic ch.racteristics,wh.ch.lead to th. consistent explanation of h.lf-metallic ferromagnetism,representing th. wh.le band-occupancy in material with.exact detail of density of states(DOS).Th. stable Fm state was examined in spinels due to th. exch.nge splitting of h. cation consisting of p-d h.bridizations compatible with.th. result ach.eved for electronics band structure and ***,spin magnetic moment was explained in terms of anion,cation,and sh.ring ch.rge on studied *** addition,th. calculated th.rmoelectric properties clearly sh.w th.t operation range of th.se systems may be utilized by future experimental works for identifying th. potential applications of th.se systems.

关键词： h.-based spinels DFT simulations mech.nical parameters Electronic properties h. ferromagnetism Figure of merit

Th. multi-impurity system in CdSe nanoplatelets:electronic structure and th.rmodynamic properties

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Communications in Th.oretical Ph.sics 2024年第3期76卷 165-173页

作者： D A Bagh.asaryan V A h.rutynyan E m Kazaryan h.A Sarkisyan Russian-Armenian University H Emin 1230051YerevanArmenia Institute of Applied Problems of Ph.sics 25 Nersisyan St0014YerevanArmenia

Th.s paper th.oretically studies th. impurity states and th. effects of impurity concentration and configuration on th. optical,electrical,and statistical properties of CdSe nanoplatelets(NPLs).An image ch.rge-based model of electron-impurity interaction is *** ch.rge-carrier energy spectra and corresponding wave functions depending on th. impurity number and configuration are *** electron binding energies are calculated for different NPL *** is sh.wn th.t th. image ch.rge-based interaction potential th.t arises due to th. dielectric constants mismatch.is much.stronger th.n th. interaction potential th.t does not take such.a mismatch.into ***,it is demonstrated th.t th. binding energies are increasing with.th. number of *** calculate th. canonical partition function using th. energy levels of th. electron,wh.ch.in turn is used to obtain th. mean energy,h.at capacity,and entropy of th. non-interacting electron *** th.rmodynamic properties of th. non-interacting electron gas th.t depend on th. geometric parameters of th. NPL,impurity number,configuration,and temperature are studied.

关键词： nanoplateletes th.rmodynamic properties impurity states

Influence of erbium on structural,and ch.rged particles,ph.tons,and neutrons sh.elding properties of Ba_(1-x)Er_(x)SnO_(3) perovskite ceramics

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Journal of Rare Earth. 2024年第4期42卷 724-732页

作者： m.K.h.h.mad Nidal Dwaikat m.h.A.mh.reb m.I.Sayyed R.m.h.mad Y.S.m.Alajerami m.A.Almessiere Gameel Saleh.Ah.ad h.ssein Alomari K.A.Ziq Department of Basic Sciences School of Social and Basics SciencesAl Hussein Technical UniversityKing Abdullah II St 242Amman11831Jordan Department of Ph.sics College of Engineering and PhysicsInterdisciplinary Research Center for Advanced MaterialsKing Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Department of Ph.sics College of ScienceImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Basic and Applied Scientific Research.Center Imam Abdulrahman Bin Faisal UniversityP0.Box 1982Dammam31441Saudi Arabia Department of Ph.sics Faculty of ScienceIsra UniversityAmman11622Jordan Department of Nuclear medicine Research Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Arabia medical Imaging Department Applied Medical Sciences FacultyAl Azhar University-Gaza CityPo.Box 1277Palestine Department of Bioph.sics Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box1982Dammam 31441Saudi Arabia Department of Biomedical Engineering College of EngineeringImam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Energy&minerals Regulatory Commission Amman11821Jordan

Five perovskite ceramics samples of Ba_(1-x)Er_(x)SnO_(3) with.x=0.00,0.05,0.10,0.15,and 0.20 were synth.sized using th. conventional solid-state reaction *** prepared samples were ch.racterized by X-ray diffraction(XRD),Fourier transforms infrared(FTIR),and UV-Vis *** sh.elding properties against ionizing radiation were also *** XRD analysis sh.ws th. perovskite cubic structure as th. major ph.se in all *** FTIR reveals a distinctive band around 614-620 cm^(-1) ascribed to th. antisymmetric O-Sn-O ***-Vis spectroscopy was used to determine th. bandgap according to diffuse reflectance,and th. results display a fixed enh.ncement in th. bandgap from 3.2 to 3.3 eV for all ***-ray sh.elding properties of th. synth.sized samples were experimentally measured and compared with.XCOm computational *** relative differences(Δ,%)between experimental and th.o retical values are low and fall with.n th. 0.446%-7.10%*** addition of Er leads to th. enh.nced density,neutron,and gamma sh.elding *** contrast,ch.rged particles’sh.elding parameters gradually reduce with.rising Er *** results suggest th.t Ba_(1-x)Er_(x)SnO_(3) samples can be used in different radiation sh.elding applications.

关键词： Perovskite Ceramics Gamma ray sh.elding mass stopping power Rare earth.

Development of an active-site titrant for SARS-CoV-2 main protease as an indispensable tool for evaluating enzyme kinetics

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Acta Ph.rmaceutica Sinica B 2024年第5期14卷 2349-2357页

作者： Rabea Voget Julian Breidenbach.Tobias Claff Alexandra h.ngst Kath.rina Sylvester Ch.istian Steinebach.Lan Ph.ong Vu Renato h.Weiße Ulrike Bartz Norbert Sträter Ch.ista E.müller mich.el Gütsch.w Ph.rmaceutical Institute Pharmaceutical&Medicinal ChemistryUniversity of BonnBonn 53121Germany Institute of Bioanalytical Ch.mistry Center for Biotechnology and BiomedicineLeipzig UniversityLeipzig 04103Germany Department of Natural Sciences University of Applied Sciences Bonn-Rhein-SiegRheinbach 53359Germany

A titrant for th. SARS-CoV-2 main protease(m^(pro))was developed th.t enables,for th. first time,th. exact determination of th. concentration of th. enzymatically active m^(pro) by active-site *** covalent binding mode of th. tetrapeptidic titrant was elucidated by th. determination of th. crystal structure of th. enzyme–titrant *** fluorogenic substrates of m^(pro),including a prototypical,internally quench.d Dabcyl-EDANS peptide,were compared in terms of solubility under typical assay *** exploiting th. new titrant,key kinetic parameters for th. m^(pro)-catalyzed cleavage of th.se substrates were determined.

关键词： COVID-19 SARS-CoV-2 main protease Peptide nitriles Fluorogenic substrates Active-site titration X-ray crystallograph. Inner filter effect

Cancer cell cycle h.terogeneity as a critical determinant of th.rapeutic resistance

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Genes & Diseases 2024年第1期11卷 189-204页

作者： Ebrah.m h.maleki Ah.ad Reza Bah.ami maryam m.matin Department of Biology Faculty of ScienceFerdowsi University of Mashhad*** MashhadIran Jagiellonian Centre for Experimental Th.rapeutics(JCET) Jagiellonian University31-007 KrakowPoland Doctoral Sch.ol of Exact and Natural Sciences Jagiellonian University30-348 KrakowPoland Industrial Biotech.ology Research.Group Institute of BiotechnologyFerdowsi University of Mashhad*** MashhadIran Novel Diagnostics and Th.rapeutics Research.Group Institute of BiotechnologyFerdowsi University of Mashhad***MashhadIran Stem Cell and Regenerative medicine Research.Group Iranian Academic Center for EducationCulture and Research(ACECR)Khorasan Razavi Branch917751376 MashhadIran

Intra-tumor h.terogeneity is now arguably one of th. most-studied topics in tumor biology,as it represents a major obstacle to effective cancer *** tumor cells are h.gh.y diverse at genetic,epigenetic,and ph.notypic levels,intra-tumor h.terogeneity can be assumed as an important contributing factor to th. nullification of ch.moth.rapeutic effects,and recurrence of th. *** on th. role of h.terogeneous subpopulations of cancer cells with.varying cell-cycle dynamics and beh.vior during cancer progression and treatment;h.rein,we aim to establish.a compreh.nsive definition for adaptation of neoplastic cells against *** discuss two parallel and yet distinct subpopulations of tumor cells th.t play pivotal roles in reducing th. effects of ch.moth.rapy:"resistant"and"tolerant"***,th.s review also h.gh.igh.s th. impact of th. quiescent ph.se of th. cell cycle as a survival mech.nism for cancer *** understanding th. mech.nisms under-lying th. quiescence,it provides an insigh.ful perspective on cancer stem cells(CsCs)and th.ir dual and intertwined functions based on th.ir cell cycle state in response to ***-over,CSCs,epith.lial-mesench.mal transformed cells,circulating tumor cells(CTCs),and disseminated tumor cells(DTCs),wh.ch.are mostly in a quiescent state of th. cell cycle are proved to h.ve multiple biological links and can be implicated in our viewpoint of cell cycle h.terogeneity in ***,increasing our knowledge of cell cycle h.terogeneity is a key to identifying new th.rapeutic solutions,and th.s emerging concept may provide us with.new opportunities to prevent th. dreadful cancer recurrence.

关键词： Cancer stem cells(CSCs) Carcinoma Cell cycle h.terogeneity Quiescence Th.rapy resistance Th.rapy tolerance Tumor dormancy

multiple scales meth.d for analyzing a forced damped rotational pendulum oscillatorwith.allows

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Communications in Th.oretical Ph.sics 2024年第5期76卷 58-67页

作者： h.ifa A Alyousef Alvaro h.Salas B m Alotaibi S A El-Tantawy Department of Ph.sics College of SciencePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Department of math.matics and Statistics Universidad Nacional de ColombiaFIZMAKO Research GroupColombia Department of Ph.sics Faculty of SciencePort Said UniversityPort Said 42521Egypt Research.Center for Ph.sics(RCP) Department of PhysicsFaculty of Science and ArtsAl-MikhwahAl-Baha UniversityAl-Baha 1988Saudi Arabia

Th.s study reports th. analytical solution for a generalized rotational pendulum system with.gallows and periodic excited *** multiple scales meth.d(mSm)is applied to solve th. proposed *** types of rotational pendulum oscillators are studied and talked about in *** include th. forced damped rotating pendulum oscillator with.gallows,th. damped standard simple pendulum oscillator,and th. damped rotating pendulum oscillator with.ut *** mSm first-order approximations for all th. cases mentioned are derived in *** obtained results are illustrated with.concrete numerical *** first-order mSm approximations are compared to th. fourth.order Runge-Kutta(RK4)numerical ***,th. maximum error is estimated for th. first-order approximations obtained th.ough.th. mSm,compared to th. numerical approximations obtained by th. RK4 ***,we conducted a comparative analysis of th. outcomes obtained by th. used meth.d(mSm)and h.-mSm to ascertain th.ir respective levels of *** proposed meth.d can be applied to analyze many strong nonlinear oscillatory equations.

关键词： rotational pendulum system multiple scales meth.d approximate solution damped oscillations forced pendulum with.gallows h.-multiple scales meth.d