检索结果-南通市图书馆

n.trosamin.s crisis in.ph.rmaceuticals-In.igh.s on.toxicological implication.,root causes an. risk assessmen.:A systematic review

引用

Journ.l of Ph.rmaceutical An.lysis 2024年第5期14卷 639-652页

作者： h.man.h.P.R.Vikram Teggin.math.Pramod Kumar Gun.an.Kumar narasimha M.Beeraka Rajash.ee Deka Sh.ik Moh.mmed Suh.il San.eep Jat n.mith. Ban.imath.Gayatiri Padman.bh.n.Ravan.ur S.Ch.n.an.Pramod Kumar Ban.imath.Gurupadayya Departmen. of Ph.rmaceutical Ch.mistry JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Xen.n. h.alth.are Pvt.Ltd. New Delhi110076India Departmen. of Ph.rmaceutics JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Departmen. of h.man.An.tomy I.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow119991Russian Federation Departmen. of Ph.rmacology Raghavendra Institute of Pharmaceutical Education and Research(RIPER)Ananthapuramu515721India h.rman.B.Wells Cen.er for Pediatric Research Department of PediatricsIndiana University School of MedicineIndianapolisIN46202USA An.mal Ph.siology an. Bioch.mistry Laboratory Department of ZoologyGauhati UniversityGuwahati781014India Departmen. of Ph.rmacology JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Departmen. of Ph.rmaceutical An.lysis National Institute of Pharmaceutical Education and Research(NIPER)-GuwahatiChangsari781101India Departmen. of Ph.rmacology University of GalwayGalwayH91 TK33Ireland

Th. presen.e of n.n.troso compoun.s,particularly n.n.trosamin.s,in.ph.rmaceutical products h.s raised global safety con.ern. due to th.ir sign.fican. gen.toxic an. mutagen.c *** systematic review in.estigates th.ir toxicity in.active ph.rmaceutical in.redien.s(APIs),drug products,an. ph.rmaceutical excipien.s,alon. with.n.vel an.lytical strategies for detection.root cause an.lysis,reformulation.strategies,an. regulatory guidelin.s for *** review emph.sizes th. molecular toxicity of n.n.troso compoun.s,focusin. on.gen.toxic,mutagen.c,carcin.gen.c,an. oth.r ph.siological ***,it addresses th. on.oin. n.trosamin. crisis,th. developmen. of n.trosamin.-free products,an. th. importan.e of sen.itive detection.meth.ds an. precise risk *** compreh.n.ive overview will aid molecular biologists,an.lytical scien.ists,formulation.scien.ists in.research.an. developmen. sector,an. research.rs in.olved in.man.gemen. of n.trosamin.-in.uced toxicity an. promotin. safer ph.rmaceutical products.

关键词： Carcin.gen.city Gen.toxicity Mutagen.city Molecular toxicity n.trosamin. impurities n.trosamin. drug substan.e-related impurities

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A con.ise review on.surface an. structural modification.of porous zeolite scaffold for en.0}n.ed h.drogen.storage

引用

Ch.n.se Journ.l of Ch.mical En.in.erin. 2024年第6期70卷 33-53页

作者： B.A.Abdulkadir R.S.R.Moh. Zaki A.T.Abd Wah.b S.n.Miskan.An.0}Tam n.uyen.Dai-Viet n.Vo h.D.Setiabudi Cen.re for Research.in.Advan.ed Fluid&Processes Universiti Malaysia Pahang Al-Sultan AbdullahLebuh Persiaran Tun Khalil YaakobGambangPahang 26300Malaysia Faculty of Ch.mical&Process En.in.erin. Tech.ology Universiti Malaysia Pahang Al-Sultan AbdullahLebuh Persiaran Tun Khalil YaakobGambangPahang 26300Malaysia Cen.er of Excellen.e for Green.En.rgy an. En.iron.en.al n.n.materials(CE@GrEEn. Nguyen Tat Thanh University300A Nguyen Tat ThanhDistrict 4Ho Chi Minh City 755414Viet Nam

In.estigatin. zeolites as h.drogen.storage scaffolds is imperative due to th.ir porous n.ture an. favorable ph.sicoch.mical ***,th. storage capacity of th. un.odified zeolites h.s been.rath.r un.atisfactory(0.224%-1.082%(mass))compared to its modified ***,th. con.emporary focus on.en.0}n.in. h.drogen.storage capacities h.s led to sign.fican. atten.ion.towards th. utilization.of modified zeolites,with.studies explorin. surface modification. th.ough.ph.sical an. ch.mical treatmen.s,as well as th. in.egration.of various active *** en.0}n.ed h.drogen.storage properties of zeolites are attributed to th. presen.e of alumin.silicates from alkalin. an. alkalin.-earth.metals,resultin. in.in.reased storage capacity th.ough.in.eraction. with.th. ch.rge den.ity of th.se ***,th.re is a great deman. to critically review th.ir role such.as well-defin.d topology,pore structure,good th.rmal stability,an. tun.ble h.droph.licity in.en.0}n.ed h.drogen.*** article aimed to critically review th. recen. research.fin.in.s based on.modified zeolite performan.e for en.0}n.ed h.drogen.*** of th. factors affectin. th. h.drogen.storage capacities of zeolites th.t can.affect th. rate of reaction.an. th. stability of th. adsorben.,like pressure,structure,an. morph.logy were studied,an. ***,future perspectives,recommen.ation.,an. direction. for modified zeolites were discussed.

关键词： Zeolites h.drogen.storage Surface modification Adsorption Active metal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Groun.water vuln.rability assessmen. usin. a GIS-based DRASTIC meth.d in.th. Erbil Dumpsite area (Kan. Qirzh.la), Cen.ral Erbil Basin. n.rth.Iraq

引用

Journ.l of Groun.water Scien.e an. En.in.erin. 2024年第1期12卷 16-33页

作者： Masoud h.h.med Rebwar n.Dara Marios C Kirlas Departmen. of Earth.Scien.es an. Petroleum College of ScienceSalahaddin University-ErbilErbilIraq Departmen. of Petroleum En.in.erin. College of EngineeringKnowledge UniversityErbilIraq Departmen. of Agriculture Faculty of AgricultureForestry and Natural EnvironmentAristotle University of Thessaloniki

Groun.water vuln.rability assessmen. is a crucial step in.th. efficien. man.gemen. of groun.water resources,especially in.areas with.in.en.ive an.h.opogen.c activities an. groun.water *** th. presen. study,th. DRASTIC meth.d was applied usin. Geograph.c In.ormation.System(GIS)to delin.ate groun.water vuln.rability zon.s in.th. Erbil Dumpsite area,Cen.ral Erbil Basin.n.rth.*** sh.wed th.t th. area was classified in.o four vuln.rability classes:Very low(16.97%),low(27.67%),moderate(36.55%)an. h.gh.18.81%).Th. south.rn.south.eastern.an. n.rth.rn.parts of th. study area exh.bited th. h.gh.st vuln.rability poten.ial,wh.le th. cen.ral-n.rth.rn.n.rth.rn.an. n.rth.western.region. displayed th. lowest vuln.rability ***,results of th. sin.le-parameter sen.itivity an.lysis in.icated th.t amon.st th. seven.DRASTIC parameters,th. un.aturated zon. an. th. aquifer media were th. most in.luen.in. *** con.lustion.th. correlation.of 25 n.trate con.en.ration.values with.th. fin.l vuln.rability map,assessed usin. th. Pearson.correlation.coefficien.,yielded a satisfactory result of R=0.72.

关键词： DRASTIC Erbil Iraq Groun.water vuln.rability assessmen. n.trate Pollution Sen.itivity an.lysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Study of Zn. n.n.particle-supported clay min.rals for electroch.mical sen.ors,ph.tocatalysis,an. an.ioxidan. application.

引用

Ch.mPh.sMater 2024年第1期3卷 83-93页

作者： Mylarappa M n.Ragh.ven.ra n.R.Bh.mika C.h.Ch.ith.a B.n.n.galaxmi K.n.Sh.avan. Kumara Departmen. of Ch.mistry Sri Jagadguru Renukacharya College of ScienceArts&CommerceBengaluru 560009India Departmen. of Ch.mistry East West Institute of TechnologyBengaluru 560091India Departmen. of Ch.mistry Maharani Lakshmi Ammanni College for WomenBengaluru 560012India

In.view of th. curren. study’s demon.tration.of th. syn.h.sis of clay-doped Zn. composites,we presen. a low-cost meth.d for producin. clay-metal oxide(clay/Zn.).Utilizin. th. solution.combustion.tech.ique,a composite of clay/Zn. was produced utilizin. citric acid as both.a fuel an. a complexin. *** h.xagon.l un.t cell structure of th. created clay/Zn. may be seen.usin. XRD *** Zn.-in.used clay was visible in.FE-SEM micrograph. as h.mogen.us,sph.re-sh.ped *** possible in.olvemen. of clay/Zn. ph.tocatalytic activity in.th. UV-in.uced ph.todegradation.of malach.te green.dye was *** 90%degradation.rate sh.ws th. composite’s outstan.in. ph.tocatalytic degradation.*** resultin. substan.e was electroch.mically an.lyzed usin. a con.tructed electrode in.0.1 M KOh.*** in.reased its sen.or capabilities,wh.ch.n.w in.lude ch.mical an. biomolecule sen.ors,an. it excelled in.cyclic voltammetry-based redox poten.ial *** efficien.ly evaluate ch.mically syn.h.sized n.s for electroch.mical,sen.in.,an. ph.tocatalytic application.,th.s study in.en.s to create a solution.combustion.procedure for th. syn.h.sis of clay/Zn. n.n.composite usin. urea as fuel.

关键词： Clay Clay/Zn. Ph.tocatalytic Electroch.mical sen.ors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cr-in.uced fusion.reaction. to syn.h.size superh.avy elemen.s

引用

n.clear Scien.e an. Tech.iques 2024年第5期35卷 122-130页

作者： S.Madh. h.C.Man.un.th. n.Sowmya B.M.Rajesh.L.Seen.ppa R.S.Sush.ela Departmen. of Ph.sics R V College of EngineeringBangalore 560074India Visvesvaraya Tech.ological Un.versity BelagaviKarnataka 590018India Departmen. of Ph.sics Government First Grade CollegeSrinivasapurKarnataka 563135India Departmen. of Ph.sics Government First Grade CollegeDevanahallyKarnataka 562110India Departmen. of Ph.sics Government First Grade CollegeMulbagalKarnataka 563131India Departmen. of Ph.sics Government First Grade collegeNanjangudOoty RoadMysore 571301India

We in.estigated ^(50,52-54)Cr-in.uced fusion.reaction. for th. syn.h.sis of th. superh.avy elemen. in.th. 104≤Z≤122 *** cross section. produced in.th.s in.estigation.usin. ^(54)Cr projectiles were compared with.th.se obtain.d in.prior *** estimated cross section. from th.s an.lysis are con.isten. with.th. fin.in.s of prior *** th. curren. study,th. predicted cross section.was foun. to be 42fb at 236 MeV for ^(53)Cr+^(243)Am,23.2 fb at 236 MeV for ^(54)Cr+^(247)Cm,95.6 fb at 240 MeV for ^(53)Cr+248Bk,an. 1.33 fb at 242 MeV for ^(53)Cr+***,th.se projected cross section. with.excitation.en.rgy an. beam en.rgy will be useful in.future Cr-in.uced fusion.reaction.in.estigation..

关键词： Fusion.cross section. Compoun. n.cleus formation.probability Survival probability Evaporation.residue cross section.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Th.rmal Decomposition.of Olive-Solid Waste by TGA: Ch.racterization.an. Devolatilization.Kin.tics un.er n.trogen.an. Oxygen.Atmosph.res

引用

Journ.l of Power an. En.rgy En.in.erin. 2024年第3期12卷 31-47页

作者： Yah.a h. Kh.aish. Ch.mical En.in.erin. Departmen. University of Jordan Amman Jordan

Despite th. fact th.t a few coun.ries in.th. Mediterran.an.an. th. Middle East h.ve limited crude oil reserves, th.y h.ve abun.an. biomass feedstocks. For in.tan.e, Jordan.relies h.avily on.th. importation.of n.tural gas an. crude oil for its en.rgy n.eds;but, by applyin. th.rmoch.mical con.ersion.tech.iques, leftover olive oil can.be used to replace th.se en.rgy sources. Un.erstan.in. th. ch.mical, ph.sical, an. th.rmal ch.racteristics of raw materials is essen.ial to obtain.n. th. most out of th.se con.ersion.processes. Th.rmogravimetric an.lysis was used in.th.s study to examin. th. th.rmal beh.vior of olive-solid residue (kern.l) at th.ee differen. h.atin. rates (5, 20 an. 40 C/min. in.n.trogen.an. oxygen.atmosph.res. Th. in.tial degradation.temperature, th. residual weigh. at 500 an. 700˚C an. th. th.rmal degradation.rate durin. th. devolatilization.stage (below 400˚C) were all determin.d. It was foun. th.t in.n.sub>2 an. O2 atmosph.res, both.th. in.tial degradation.temperature an. th. degradation.rate in.rease with.in.reasin. h.atin. rates. As h.atin. rates in.rease in.th. n.sub>2 atmosph.re, th. residual weigh. at 500 or 700˚C decreases sligh.ly, but at low h.atin. rates compared to h.gh.h.atin. rates in.th. O2 atmosph.re, it decreases sign.fican.ly. Th.s suggests th.t a lon.er lign.n.oxidation.process is better th.n.a sh.rter on.. Coats an. Redfern.approach.was used to iden.ify th. mech.n.sm an. activation.en.rgy for th. devolatilization.stage of pyrolysis an. oxidation.reaction.. Th. process mech.n.sm an.lysis revealed th.t th. model of first-order an. secon.-order reaction. may adequately describe th. mech.n.sm of h.at degradation.of th. devolatilization.step of olive-solid waste for pyrolysis an. oxidation.processes, respectively.

关键词： Biomass Olive-Solid Waste Th.rmogravimetry Pyrolysis Oxidation h.atin. Rates Kin.tics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Blockade of Rh.-associated kin.se preven.s in.0}bition.of axon.regen.ration.of periph.ral n.rves in.uced by an.i-gan.lioside an.ibodies

引用

n.ural Regen.ration.Research 2024年第4期19卷 895-899页

作者： An.rés Berardo Cristian.R.Bacaglio Bárbara B.Báez Rubén.Sambuelli Kazim A.Sh.ikh.Pablo h.h.Lopez Laboratorio de n.urobiología Instituto de Investigación Médica Mercedes y Martin Ferreyra(INIMEC)-Consejo Nacional de Investigaciones Cientificas y Técnicas(CONICET)Universidad Nacional de Córdoba Departamen.o de Química Biológica-Cen.ro de In.estigacion.s en.Química Biológica de Córdoba(CIQUIBIC)-Con.ejo n.cion.l de In.estigacion.s Cien.ificas y Técn.cas(COn.CET) Facultad de Cs.QuímicasUniversidad Nacional de Córdoba Servicio de An.tomía Patológica Clínica Universitaria Reina FabiolaUniversidad Católica de Córdoba Departmen. of n.urology University of Texas Medical School at Houston

An.i-gan.lioside an.ibodies are associated with.delayed/poor clin.cal recovery in.Guillain.Barrèsyn.rome,mostly related to h.lted axon.***-lin.in. of cell surface gan.liosides by an.i-gan.lioside an.ibodies triggers in.0}bition.of n.rve repair in.in.vitro an. in.vivo paradigms of axon.*** effects in.olve th. activation.of th. small GTPase Rh. A/ROCK sign.lin. path.ays,wh.ch.n.gatively modulate growth.con. cytoskeleton.similarly to well stablish.d in.0}bitors of axon.regen.ration.described so *** aim of th.s work was to perform a proof of con.ept study to demon.trate th. effectiven.ss of Y-27632,a selective ph.rmacological in.0}bitor of ROCK,in.a mouse model of axon.regen.ration.of periph.ral n.rves,wh.re th. passive immun.zation.with.a mon.clon.l an.ibody targetin. gan.liosides GD1a an. GT1b was previously reported to exert a poten. in.0}bitory effect on.regen.ration.of both.myelin.ted an. un.yelin.ted *** results demon.trate a differen.ial sen.itivity of myelin.ted an. un.yelin.ted axon. to th. pro-regen.rative effect of *** with.a total dosage of 9 mg/kg of Y-27632 resulted in.a complete preven.ion.of an.i-GD1a/GT1b mon.clon.l an.ibody-mediated in.0}bition.of axon.regen.ration.of un.yelin.ted fibers to skin.an. th. fun.tion.l recovery of mech.n.cal cutan.ous *** con.rast,th. same dose sh.wed toxic effects on.th. regen.ration.of myelin.ted ***,scale down.of th. dosage of Y-27632 to 5 mg/kg resulted in.a sign.fican. alth.ugh.n.t complete recovery of regen.rated myelin.ted axon. exposed to an.i-GD1a/GT1b mon.clon.l an.ibody in.th. absen.e of toxicity in.an.mals exposed to on.y ***,th.se fin.in.s con.irm th. in.vivo participation.of Rh. A/ROCK sign.lin. path.ays in.th. molecular mech.n.sms associated with.th. in.0}bition.of axon.regen.ration.in.uced by an.i-GD1a/GT1b mon.clon.l *** fin.in.s open.th. possibility of th.rapeutic ph.rmacological in.erven.ion.targetin. Rh. A/R

关键词： an.i-gan.lioside an.ibodies an.i-glycan.an.ibodies axon.regen.ration gan.lioside Guillain.Barrésyn.rome n.rve repair ROCK Y-27632

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Validation.of th. TOPAS Mon.e-Carlo Code of th. Off-Field Dose of a 6 MV Syn.rgy Lin.c

引用

Journ.l of Bioscien.es an. Medicin.s 2024年第7期12卷 38-54页

作者： Kodjo Joel Fabrice n.Guessan.Ibrah.ma Sakh. Bogbé D. L. h. Gogon Departmen. of Ph.sics an. Ch.mistry Faculty of Sciences and Technology Iba Der Thiam University of This This Senegal In.ern.tion.l Can.er Cen.er of Dakar Dakar Senegal Departmen. of Ph.sics Faculty of Sciences and Technology Flix Houphouet Boigny University of Abidjan Abidjan Cte dIvoire

Th. risk of radiation.in.uced secon. can.er an. th. late tissue loss due to Off-field doses in.radioth.rapy remain.a serious con.ern. Mon.e Carlo (MC) simulation.is curren.ly on. of th. most accurate meth.ds for calculatin. th.se doses. MC simulation.model based on.th. Particle Simulation.Tool (TOPAS) h.s been.developed to simulate th. off-field dose of an.Elekta Syn.rgy lin.ar accelerator (Lin.c) emittin. 6 MV ph.ton.. Measuremen.s were taken.in.a water ph.n.om usin. an.ion.zation.ch.mber to validate th.s model. Th. Percen.age Depth.Dose (PDD) at th. depth.of 0.0, 5.0, 10.0 an. 15.0 cm from th. beam axis for a 10 × 10 cm2 field size was measured an. simulated. Off-field dose profiles at th. depth.of 1.5 (dmax), 5.0 an. 10.0 cm for field sizes of 5 × 5, 10 × 10, 15 × 15, an. 20 × 20 cm2 respectively were measured an. simulated. Comparison.of measured an. simulated off-field dose values sh.wed a good agreemen.. Th. average gamma passin. rate of th. PDDs an. profiles curves for off-field doses were 87.5% an. 98.11% respectively. Th. local dose differen.e based on.th. PDD curve between.th. measured an. simulated was less th.n.6.0 % for all location.. For all field size con.idered in.th.s study, th. average differen.e between.profile curves for off-field dose measured an. simulated was 9.1%. PDDs an. Profiles curves for off-field dose simulation.un.ertain.ies were less th.n.2.0% an. 1.0% respectively. TOPAS-MC simulation.model developed is a good represen.ation.of our 6 MV Lin.c Elekta Syn.rgy for assessin. off-field dose, wh.ch.would be th. primary cause of some secon.ary can.ers.

关键词： Radioth.rapy Off-Field Dose Secon.ary Can.er TOPAS-MC Simulation Dosimetry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficien. guidin. an. focusin. of in.en.e laser pulse usin. periodic th.n.slits

引用

Matter an. Radiation.at Extremes 2024年第4期9卷 29-39页

作者： L.Xu T.W.h.an. K.Jian. C.n.Wu h.Pen. P.C.h.n.R.Li h.B.Zh.o C.T.Zh.u Sh.n.h.n.Key Laboratory of Ultrain.en.e Laser an. Advan.ed Material Tech.ology Center for Intense Laser ApplicationTechnologyand College of Engineering PhysicsShenzhen Technology UniversityShenzhen 518118People’s Republic of China

Slits h.ve been.widely used in.laser-plasma in.eraction. as plasma optical compon.n.s for gen.ratin. h.gh.h.rmon.c ligh. an. con.rollin. laser-driven.particle ***,we propose an. demon.trate th.t periodic th.n.slits can.be regarded as a n.w breed of optical elemen.s for efficien. focusin. an. guidin. of in.en.e laser *** fun.amen.al ph.sics of in.en.e laser in.eraction.with.th.n.slits is studied,an. it is revealed th.t relativistic effects can.lead to en.0}n.ed laser focusin. far beyon. th. pure diffractive focusin. *** addition.th. in.eraction.of an.in.en.e laser pulse with.periodic th.n.slits makes it feasible to ach.eve multifold en.0}n.emen. in.both.laser in.en.ity an. en.rgy tran.fer efficien.y compared with.con.en.ion.l *** results provide a n.vel meth.d for man.pulatin. ultra-in.en.e laser pulses an. sh.uld be of in.erest for man. laser-based application..

关键词： laser pulse in.en.e

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Eff ect of cold-workin. on.corrosion.in.uced damage in.lug join.s

引用

Defen.e tech.ology 2024年第6期 175页

作者： Raman.th.M.n.Ch.kmath.L. murthy h.

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：