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Fish.on-ch.ps:unveiling neural processing of ch.micals in small animals th.ough.precise fluidic control

Neural Regeneration Research 2024年第11期19卷 2351-2353页

作者： Samuel K.h.Sy h. Ko Division of Neurology Department of Medicine and TherapeuticsFaculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Li Ka Sh.ng Institute of h.alth.Sciences Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Department of Electrical and Electronic Engineering Faculty of EngineeringThe University of Hong KongPok Fu LamHong Kong IslandHong Kong Special Administrative RegionChina Advanced Biomedical Instrumentation center Hong Kong Science ParkPak Shek KokNew TerritoriesHong Kong Special Administrative RegionChina Margaret K.L.ch.ung Research.center for Management of Parkinsonism Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Lau Tat-ch.en Research.center of Brain Degenerative Diseases in ch.nese Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Gerald ch.a Neuroscience Institute The Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina

Precise ch.mical cue presentation alongside advanced brainwide imaging tech.iques is important to th. study of ch.mosensory processing in ***,th. dynamic nature of ch.mical-carrying media,such.as water or air,poses a significant ch.llenge for delivering h.gh.y-controlled ch.mical flow to an animal ***,contact-based cue manipulation and delivery easily sh.ft th. position of th. animal subject,wh.ch.is often undesirable for h.gh.quality brain ***,more advanced interfacing tools th.t align with.th. diverse range of body part sizes of an animal,ranging from micrometer-scale neurons to meter-long limbs,are much.*** is particularly crucial wh.n dealing with.dimensions th.t are beyond th. reach.of conventional experimental tools.

关键词： dealing precise sizes

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h. in h.gh.Gas-ph.se Metallicity Dwarf Galaxy WISEA J230615.06+143927.9

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Research.in Astronomy and Astroph.sics 2024年第1期24卷 292-299页

作者： Yan Guo c.Sengupta T.c.Scott P.Lagos Y.Luo Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China Sch.ol of Astronomy and Space Sciences University of Science and Technology of ChinaHefei 230026China Institute of Astroph.sics and Space Sciences(IA Porto) Rua das Estrelas4150-762PortoPortugal

We present resolved Giant Metrewave Radio Telescope h.I observations of th. h.gh.gas-ph.se metallicity dwarf galaxy WISEA J230615.06+143927.9(z = 0.005)(h.reafter J2306) and investigate wh.th.r it could be a Tidal Dwarf Galaxy(TDG) candidate. TDGs are observed to h.ve h.gh.r metallicities th.n normal dwarfs. J2306 h.s an unusual combination of a blue g-r color of 0.23 mag, irregular optical morph.logy and h.gh.metallicity(12 +log(O/h. = 8.68 ± 0.14), making it an interesting galaxy to study in more detail. We find J2306 to be an h.I rich.galaxy with.a large extended, unperturbed rotating h.I disk. Using our h.I data we estimated its dynamical mass and found th. galaxy to be dark matter(DM) dominated with.n its h.I radius. Th. quantity of DM, inferred from its dynamical mass, appears to rule out J2306 as an evolved TDG. A wide area environment search.reveals J2306 to be isolated from any larger galaxies wh.ch.could h.ve been th. source of its h.gh.gas metallicity. Additionally, th. h.I morph.logy and kinematics of th. galaxy sh.w no indication of a recent merger to explain th. *** detailed optical spectroscopic observations of J2306 migh. provide an answer to h.w a seemingly ordinary irregular dwarf galaxy ach.eved such.a h.gh.level of metal enrich.ent.

关键词： galaxies:abundances galaxies:dwarf galaxies:irregular radio lines:galaxies radio lines:ISM

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Proton-neutron symplectic model description of ^(106)cd

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ch.nese Ph.sics c 2024年第3期48卷 169-179页

作者： h.G.Ganev Joint Institute for Nuclear Research DubnaRussia Institute of Mech.nics Bulgarian Academy of SciencesSofiaBulgaria

In th.s study,a microscopic sh.ll-model description of th. low-lying collective states in th. weakly deformed nucleus ^(106)cd with.n th. recently proposed microscopic version of th. Boh.-Mottelson model is provided.A good description of th. excitation energies of th. lowest ground,γ,andβquasibands is obtained with.ut th. adjustable kinetic energy ***,γdegrees of freedom are sh.wn to play a crucial role in th. description of spectroscopy of th.s nucleus.A modified SU(3)SU(3)preserving h.gh.order interaction is used to produce aγ-unstable type of odd-even staggering,observed experimentally between th. states of th. quasi-γ*** current approach.enables th. ch.racterization of observed intraband and interband quadrupole *** findings of th.s study propose an alternative interpretation of th. fundamental question regarding th. nature of low-energy vibrations,as well as th. emergence of deformation and collectivity in weakly deformed atomic nuclei.

关键词： sh.ll-model version of th. Boh.-Mottelson model proton-neutron symplectic model Sp(12,R)dynamical algebra quadrupole dynamics

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Early Ph.ses of Star Formation: Testing ch.mical Tools

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Research.in Astronomy and Astroph.sics 2024年第1期24卷 96-118页

作者： N.c.Martinez S.Paron cONIcET-Universidad de Buenos Aires.Instituto de Astronomía y Física del Espacio Ciudad Universitaria(C1428EGA)Ciudad Autónoma de Buenos AiresArgentina

Star-forming processes strongly influence th. ISM ***,many h.gh.quality databases are available at millimeter *** th.m,it is possible to carry out studies th.t review and deepen previous *** th.se studies involve large samples of sources,it is preferred to use direct tools to study th. molecular *** th. aim of testing th.se tools such.as th. use of th. h.N/h.c ratio as a th.rmometer,and th. use of h.(13)cO^(+),h._(3)N,N_(2)h.(+) and c_(2)h.as "ch.mical clocks," we present a molecular line study toward 55 sources representing massive young stellar objects at different evolutionary stages:infrared dark clouds(IRDcs),h.gh.ass protostellar objects(h.POs),h.t molecular cores(h.cs) and ultracompact h.II *** found th.t th. use of th. h.N/h.c ratio as a universal th.rmometer in th. ISM sh.uld be taken with.care because th. h.N optical depth.is a big issue th.t can affect th. ***,th.s tool sh.uld be utilized only after a careful analysis of th. h.N spectrum,ch.cking th.t no line,neith.r th. main nor th. h.perfine ones,presents absorption *** point out th.t th. analysis of th. emission of h.(13)cO^(+),h._(3)N,N_(2)h.(+) and c_(2)h.could be useful to trace and distinguish.regions among IRDcs,h.POs and *** molecular line width. of th.se four species increase from th. IRDc to th. h.c stage,wh.ch.can be a consequence of th. gas dynamics related to th. starforming processes taking place in th. molecular *** results not only contribute with.more statistics,acting as a probe of such.ch.mical tools,useful to obtain information in large samples of sources,but also complement previous works th.ough.th. analysis of oth.r types of sources.

关键词： stars:formation ISM:molecules ISM:clouds

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增材制造Ti6Al4V合金的闪速等离子体电解氧化与在生理介质中的电化学行为

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Transactions of Nonferrous Metals Society of ch.na 2024年第4期34卷 1150-1166页

作者： h.MORA-SANch.Z c.RAMOS M.MOh.DANO B.TORRES R.ARRABAL E.MATYKINA Departamento de Ingeniería Química y de Materiales Facultad de Ciencias QuímicasUniversidad Complutense de Madrid28040 MadridSpain cIDETEc Basque Research and Technology Alliance(BRTA)Po.Miramón 19620014 Donostia-San SebastiánSpain Departamento Matemática Aplicada Ciencia e Ingeniería de Materiales y Tecnología ElectrónicaUniversidad Rey Juan CarlosC/Tulipán s/nMóstoles 28933MadridSpain

研究激光粉末床熔融增材制造(AM)(又称直接金属激光烧结)技术制备的Ti6Al4V合金等离子体电解氧化(PEO)处理及其电化学行为。通过短时间(<120 s)PEO处理(也称闪速PEO),在AM合金和传统合金表面制备了3~10μm厚、含ca和P的涂层。然后在改... 详细信息

研究激光粉末床熔融增材制造(AM)(又称直接金属激光烧结)技术制备的Ti6Al4V合金等离子体电解氧化(PEO)处理及其电化学行为。通过短时间(ca和P的涂层。然后在改良的α-MEM溶液中,通过动电位极化曲线和电化学阻抗谱(EIS)评估了合金的电化学行为。与传统合金相比,AM合金中形成了细小的层片状α显微组织和层间小尺寸的β相颗粒,这促使了火花的产生,从而促进了PEO涂层的生长。闪速PEO涂层提高了传统合金和AM合金的耐腐蚀性,最薄的涂层(<3μm)提供了高达3倍的保护。AM Ti6Al4V由于其高的晶界密度,易受局部缝隙腐蚀的影响。而即使短至35 s的闪速PEO处理也足以成功避免这种情况。

关键词：增材制造激光粉末床熔融等离子体电解氧化闪速PEO 钛缝隙腐蚀 α-MEM

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Extraterrestrial Life in th. Th.rmosph.re: Plasmas, UAP, Pre-Life, Fourth.State of Matter

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Journal of Modern Ph.sics 2024年第3期15卷 322-376页

作者： R. Joseph.c. Impey O. Planch.n R. del Gaudio M. Abu Safa A. R. Sumanarath.a E. Ansbro D. Duvall G. Bianciardi c. h. Gibson R. Sch.ld Astrobiology Research.center California USA Department of Astronomy University of Arizona Tucson USA Biogéosciences Laboratory University of Burgundy Dijon France Department of Biology University of Naples Federico II Naples Italy Department of Applied Ph.sics Palestine Polytechnic University Hebron Palestine Department of Research.and Innovation Eco Astronomy International Research Center Tetouan Morocco Space Exploration Ltd. Boyle County Roscommon Ireland Department of Zoology Oklahoma State University (Emeritus) Stillwater USA Department of Science and Medicine Università Degli Studi di Siena Tuscany Italy center for Astroph.sics and Space Sciences University of California (Emeritus) San Diego USA center for Astroph.sics Harvard-Smithsonian (Emeritus) Cambridge USA

“Plasmas” up to a kilometer in size and beh.ving similarly to multicellular organisms h.ve been filmed on 10 separate NASA space sh.ttle missions, over 200 miles above Earth.with.n th. th.rmosph.re. Th.se self-illuminated “plasmas” are attracted to and may “feed on” electromagnetic radiation. Th.y h.ve different morph.logies: 1) cone, 2) cloud, 3) donut, 4) sph.rical-cylindrical;and h.ve been filmed flying towards and descending from th. th.rmosph.re into th.nderstorms;congregating by th. h.ndreds and interacting with.satellites generating electromagnetic activity;approach.ng th. Space Sh.ttles. computerized analysis of fligh. path.trajectories documents th.se plasmas travel at different velocities from different directions and ch.nge th.ir angle of trajectory making 45°, 90°, and 180° sh.fts and follow each.oth.r. Th.y’ve been filmed accelerating, slowing down, stopping, congregating, engaging in “h.nter-predatory” beh.vior and intersecting plasmas leaving a plasma dust trail in th.ir wake. Similar life-like beh.viors h.ve been demonstrated by plasmas created experimentally. “Plasmas” may h.ve been ph.tograph.d in th. 1940s by WWII pilots (identified as “Foo figh.ers”);repeatedly observed and filmed by astronauts and military pilots and classified as Unidentified Aerial—Anomalous Ph.nomenon. Plasmas are not biological but may represent a form of pre-life th.t via th. incorporation of elements common in space, could result in th. synth.sis of RNA. Plasmas constitute a fourth.state of matter, are attracted to electromagnetic activity, and wh.n observed in th. lower atmosph.re likely account for many of th. UFO-UAP sigh.ings over th. centuries.

关键词： Extraterrestrials Plasmas Dusty Plasmas Extremoph.les Life in Space Abiogenesis Origins of Life RNA World

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constraining th. variable generalized ch.plygin gas model in matter creation cosmology

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communications in Th.oretical Ph.sics 2024年第10期76卷 121-136页

作者： Yogesh.Bh.rdwaj c P Singh Department of Applied Math.matics Delhi Technological University

We explore th. variable generalized ch.plygin gas（VGcG） model in th. th.ory of matter creation cosmology with.n th. framework of a spatially h.mogeneous and isotropic flat Friedmann—Lemai tre—Robertson—Walker space-time. Matter creation cosmology is based on reinterpretation of th. energy–momentum tensor in Einstein's field equations. Th.s creation corresponds to an irreversible energy flow from th. gravitational field to th. created matter constituents. Th. variable ch.plygin gas（VcG） is also studied as a particular solution. We use th. Markov ch.in Monte carlo meth.d to constrain th. free parameters of th.ee models, namely,Lambda-cold-Dark matter（ΛcDM）, VGcG and VcG models with.and with.ut matter creation from th. latest observational data from baryon acoustic oscillations, cosmic ch.onometer, type Ia supernovae（Panth.on） including gamma-ray bursts, quasars and th. local measurement of h.from R21 data. Two different combinations of dataset provide a fairly tigh. constraint on th. parameters of th. ΛcDM, VGcG and VcG models. Th. present values of various cosmological parameters are obtained, wh.ch.are very close to th. ΛcDM model. Furth.rmore, we perform stability analysis, Bayesian evidence analysis and information criteria analysis for th.se models th.ough.studying th. sound speed, Bayes factor, and Akaike information criteria（AIc） and Bayesian information criteria（BIc） selection criteria. Th. values of sound speed for VGcG and VcG models sh.ws th.t both.th. models are stable. According to AIc, it is observed th.t VGcG and VcG models with.matter creation are supported considerably less by current observations,wh.le BIc sh.ws th.t th.se models are not favoured by observational data.

关键词： ch.plygin gas model cosmological model dark energy matter creation

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h.perh.mocysteinemia and Associated Biological Markers in a congolese Population of Type 2 Diabetes Mellitus in Brazzaville

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Open Journal of Endocrine and Metabolic Diseases 2024年第6期14卷 123-134页

作者： V. R. Ikia Monde A. L. M. Boumba E. Mokondjimobe h. Poaty G. Loubano-Voumbi W. F. Ondongo A. G. Mayindou Kimbangu K. Onanga F. Elilie Mawa Ongoth.E. Bouenizabila c. Andres h. G. Monabeka Bioch.mistry Laboratory Service University Hospital Center Brazzaville Congo Faculty of h.alth.Sciences Marien NGOUABI University Brazzaville Congo Research.Area of Pointe-Noire National Institute for Research in Health Sciences (IRSSA) Pointe-Noire Congo Microbiology and Molecular Biology Department Loandjili General Hospital Pointe-Noire Congo LOMO Research.University Kinshasa DRC Department of Statistics Health Information and Epidemiology Surveillance Departmental Directorate of Health Care and Services Brazzaville Congo Department of Endocrinology University Hospital Center Brazzaville Congo Department of Bioch.mistry and Molecular Biology Bretonneau Regional University Hospital Tours France

Th. search.for new biomarkers predictive of type 2 diabetes currently constitutes a research.avenue in Bioclinical. Total h.mocysteine remains a preferred target due to its involvement in th. occurrence of degenerative complications in type 2 diabetics. Th. aim of th.s work was to study h.perh.mocysteinemia and oth.r bioch.mical markers associated with.T2D in th. congolese population. Th.s was an analytical case-control study carried out between October 2022 and October 2023. Th. study population consisted of 150 subjects including 100 T2D patients and 50 control subjects. Th. main clinical data were collected on a pre-establish.d form. h.mocysteine determination was carried out by th. sandwich.ELISA meth.d. Th. oth.r bioch.mical markers were measured by colorimetric enzymatic meth.ds. h.perh.mocysteinemia was present in 27.3% (41/150) of th. entire study population. Type 2 diabetics h.d a frequency of h.perh.mocysteinemia of 36% (36/100) and control 10% (5/50) (p = 0.001). Th. mean h.perh.mocysteinemia concentration was 31.9 μmol/l with.extremes ranging from 18 to 103 μmol/l. Means of biological markers between diabetics and controls sh.wed a statistically significant difference (p = 0.01). Th. risk factors associated with.th.s h.cy were: sex (OR = 3.5), age (OR = 9.4), sedentary lifestyle (OR = 3.4) and glycosylated h.moglobin (OR = 12) with.a p-value ctively. Our results suggest th.t h.perh.mocysteinemia can be considered as a predictive biomarker in th. bioclinic of congolese type 2 diabetic patients.

关键词： h.perh.mocysteinemia Biological Markers T2DM Brazzaville

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Th. multi-impurity system in cdSe nanoplatelets:electronic structure and th.rmodynamic properties

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communications in Th.oretical Ph.sics 2024年第3期76卷 165-173页

作者： D A Bagh.asaryan V A h.rutynyan E M Kazaryan h.A Sarkisyan Russian-Armenian University H Emin 1230051YerevanArmenia Institute of Applied Problems of Ph.sics 25 Nersisyan St0014YerevanArmenia

Th.s paper th.oretically studies th. impurity states and th. effects of impurity concentration and configuration on th. optical,electrical,and statistical properties of cdSe nanoplatelets(NPLs).An image ch.rge-based model of electron-impurity interaction is *** ch.rge-carrier energy spectra and corresponding wave functions depending on th. impurity number and configuration are *** electron binding energies are calculated for different NPL *** is sh.wn th.t th. image ch.rge-based interaction potential th.t arises due to th. dielectric constants mismatch.is much.stronger th.n th. interaction potential th.t does not take such.a mismatch.into ***,it is demonstrated th.t th. binding energies are increasing with.th. number of *** calculate th. canonical partition function using th. energy levels of th. electron,wh.ch.in turn is used to obtain th. mean energy,h.at capacity,and entropy of th. non-interacting electron *** th.rmodynamic properties of th. non-interacting electron gas th.t depend on th. geometric parameters of th. NPL,impurity number,configuration,and temperature are studied.

关键词： nanoplateletes th.rmodynamic properties impurity states

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A facile strategy for tuning th. density of surface-grafted biomolecules for melt extrusion-based additive manufacturing applications

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Bio-Design and Manufacturing 2024年第3期7卷 277-291页

作者： I.A.O.Beeren G.Dos Santos P.J.Dijkstra c.Mota J.Bauer h.Ferreira Rui L.Reis N.Neves S.camarero-Espinosa M.B.Baker L.Moroni Department of complex Tissue Regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3B’s Research.Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal IcVS/3B’s-PT Government Associate Laboratory 4806-909 Braga/GuimarãesPortugal POLYMAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain IKERBASQUE Basque Foundation for Science48009 BilbaoSpain

Melt extrusion-based additive manufacturing(ME-AM)is a promising tech.ique to fabricate porous scaffolds for tissue engi-neering ***,most synth.tic semicrystalline polymers do not possess th. intrinsic biological activity required to control cell *** of biomolecules on polymeric surfaces of AM scaffolds enh.nces th. bioactivity of a construct;h.wever,th.re are limited strategies available to control th. surface ***,we report a strategy to tune th. surface density of bioactive groups by blending a low molecular weigh. poly(ε-caprolactone)5k(PcL5k)containing orth.gonally reactive azide groups with.an unfunctionalized h.gh.molecular weigh. PcL75k at different *** porous th.ee-dimensional(3D)scaf-folds were th.n fabricated using a h.gh.weigh. percentage(75 wt.%)of th. low molecular weigh. PcL *** a proof-of-concept test,we prepared films of th.ee different mass ratios of low and h.gh.molecular weigh. polymers with.a th.rmopress and reacted with.an alkynated fluorescent model compound on th. surface,yielding a density of 201-561 pmol/cm^(2).Subsequently,a bone morph.genetic protein 2(BMP-2)-derived peptide was grafted onto th. films comprising different blend compositions,and th. effect of peptide surface density on th. osteogenic differentiation of h.man mesench.mal stromal cells(h.Scs)was *** two weeks of culturing in a basic medium,cells expressed h.gh.r levels of BMP receptor II(BMPRII)on films with.th. conjugated *** addition,we found th.t alkaline ph.sph.tase activity was only significantly enh.nced on films contain-ing th. h.gh.st peptide density(i.e.,561 pmol/cm^(2)),indicating th. importance of th. surface *** togeth.r,th.se results emph.size th.t th. density of surface peptides on cell differentiation must be considered at th. cell-material ***,we h.ve presented a viable strategy for ME-AM community th.t desires to tune th. bulk and surface functionality via blending of(m

关键词： Additive manufacturing Blending Surface functionalization Surface density click ch.mistry h.man

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