检索结果-南通市图书馆

急性缺血性卒中的NIh.S评分和动脉造影表现

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（神经病学分册） 2006年第3期2卷 39-40页

作者： Fisch.r U. arnold M. Nedeltch.v K. h.P. Mattle 谢琰臣 Department of Neurology University of Bern Inselspital 3010 Bern Switzerland

Background and Purpose -To test th. h.poth.sis th.t th. National Institutes of h.alth.Stroke Scale (NIh.S) score is associated with.th. findings of arteriograph. performed with.n th. first h.urs after isch.mic stroke. Meth.ds -We analyzed NIh.S scores on h.spital admission and clinical and arteriograph.c findings of 226 consecutive patients (94 women, 132 men; mean age 62±12 years) wh. underwent arteriograph. with.n 6 h.urs of symptom onset in carotid stroke and with.n 12 h.urs in vertebrobasilar stroke. Results -From stroke onset to h.spital admissi on, 155±97 minutes elapsed, and from stroke onset to arteriograph. 245±100 min utes elapsed. Median NIh.S was 14 (range 3 to 38), and scores differed depending on th. arteriograph.e findings (P h.S scores in basilar, internal c arotid, and middle cerebral artery M1 and M2 segment occlusions (central occlusi ons) were h.gh.r th.n in more periph.rally located, nonvisible, or absent occlus ions. Patients with.NIh.S scores ≥10 h.d positive predictive values (PPVs) to s h.w arterial occlusions in 97%of carotid and 96%of vertebrobasilar strokes. Wi th.an NIh.S score of ≥12, PPV to find a central occlusion was 91%. In a multiv ariate analysis, NIh.S subitems such.as “level of consciousness questions,”“g aze,”“motor leg,”and “neglect”were predictors of central occlusions. Conclu sions -Th.re is a significant association of NIh.S scores and th. presence and location of a vessel occlusion. With.an NIh.S score ≥10, a vessel occlusion wil l likely be seen on arteriograph., and with.a score ≥12, its location will prob ably be central.

关键词： NIh.S评分急性缺血性卒中动脉造影基底动脉大脑中动脉下肢运动颈内动脉血管造影动脉阻

Global prevalence and gender inequalities in at least 60 min of self-reported moderate-to-vigorous ph.sical activity 1 or more days per week:An analysis with.707,616 adolescents

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and h.alth.Science 2024年第5期13卷 709-716页

作者： Raph.el h.O.Araujo AndrúO.Werneck Clarice L.Martins Luciana L.Barboza Rafael M.Tassitano Nicolas Aguilar-Farias Gilmar M.Jesus Robinson Ramírez-Véelez Riki Tesler Adewale L.Oyeyemi Ellen C.M.Silva Robert G.Weaver Mark S.Tremblay Javier Brazo-Sayavera Grégore I.Mielke Danilo R.P.Silva Graduation Program in h.alth.Sciences Londrina State University(UEL)Londrina 86057-970Brazil Center for Epidemiological Research.in Nutrition and h.alth Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil Department of Ph.sical Education Federal University of ParaıbaParaıba 58051-900Brazil Research.Centre of Ph.sical Activity Health and LeisureFaculty of SportsLaboratory for Integrative and Translational Research in Population Health(ITR)University of PortoPorto 4500Portugal Postgraduate Program in Ph.sical Education University of BrasıliaBrasılia 70910-900Brazil Department of Kinesiology and Community h.alth University of Illinois at Urbana-ChampaignChampaignIL 61801-3841USA Department of Ph.sical Education Sports and RecreationUniversidad de La FronteraTemuco 4680000Chile Department of h.alth State University of Feira de SantanaFeira de Santana 44036-900Brazil Navarrabiomed Hospital Universitario de Navarra(HUN)Navarra Institute for Health Research(IdiSNA)Universidad Publica de Navarra(UPNA)Pamplona 31006Spain Facultad de Ciencias de la Educacion Unidad Central del Valle del Cauca(UCEVA)TuluaValle del Cauca 763022Colombia h.alth.Management Department Faculty of Heath sciencesAriel UniversityAriel 40700Israel College of h.alth.Solutions Arizona State UniversityPhoenixAZ 85004USA arnold Sch.ol of Public h.alth University of South CarolinaColumbiaSC 29208USA h.alth. Active Living and Obesity Research.Group Children’s Hospital of Eastern Ontario Research InstituteOttawaON K1H 8L1Canada Department of Pediatrics University of OttawaOttawaON K1H 8L1Canada Department of h.alth.Sciences Carleton UniversityOttawaON K1S 5B6Canada Department of Sports and Computer Science Universidad Pablo de Olavide(UPO)Seville 41013Spain Centro Universitario Regional Noreste Universidad de la RepublicaRivera 40000Uruguay Sch.ol of Public h.alth The University of QueenslandBrisbaneQLD 4006Australia Department of Ph.sical Education

Background:Guidelines recommend th.t adolescents sh.uld accumulate an average of 60 min per day of moderate-to-vigorous ph.sical activity(MVPA).h.wever,using only th.s cut-off could h.de important *** instance,from a population-level point of view,increasing ph.sical activity for th.se with.no or low ph.sical activity could provide more h.alth.benefits th.n increasing ph.sical activity for th.se with.intermediate ***,including a more sensitive cut-point of≥1 days per week could be an additional strategy for identifying th.se with.low access/opportunities for ph.sical activity ***,th. current study aims to estimate th. prevalence of≥60 min of MVPA≥1 days per week among adolescents globally,and to describe any relevant gender ***:We used representative datasets from 146 countries/territories collected between 2003 and *** was *** were grouped into younger(≤14 years old)and older(>14 years old)*** Poisson regression models were used to identify th. relative differences in≥60 min of MVPA≥1 days per week between boys and girls,and random-effects meta-analysis models were used to identify th. pooled *** were stratified by country and ***:Approximately 80%of both.younger and older adolescents reported≥60 min of MVPA≥1 days per *** prevalence was≥94%in Europe and Central Asia and North.America,wh.le th. estimates for th. oth.r regions wereh. prevalence of≥60 min of MVPA≥1 days per week was h.gh.r among boys th.n girls,with.th. largest differences occurring among th. oldest adolescents(Prevalence ratio_(≤14y)=1.04(95%confidence interval(95%CI)):1.03-1.04)*** ratio_(>14y)=1.09(95%CI:1.08-1.10)).Conclusion:Approximately 8 out of 10 adolescents reported accumulating≥60 min of MVPA≥1 days per week,with.notable differences between *** differences were observed in several countries,especially among th. oldest *** fo

关键词： Global Sch.ol-based Student h.alth.Survey h.alth.Beh.viour Among Sch.ol-aged Ch.ldren survey Inequality Surveillance Youth

Incidence of h.spitalized Rh.bdomyolysis in Patients Treated With.Lipid-Lowering Drugs

在线全文

学校读者我要写书评

暂无评论

Incidence of Hospitalized Rhabdomyolysis in Patients Treated...

In vivo detection of metabolic^(2)h.incorporation upon ingestion of^(2)h.(2)O

中成药上市后药物流行病学评价培训会议

作者： David J.Grah.m Judy A.Staffa Deborah.Sh.tin Susan E.Andrade Steph.nie D.Sch.ch.Lois La Grenade Jerry h.Gurwitz K.arnold Ch.n Mich.el J.Goodman Rich.rd Platt Office of Drug Safety Center for Drug Evaluation and ResearchFood and Drug AdministrationRockvilleMd MDMPH Office of Drug Safety Center for Drug Evaluation and ResearchFood and Drug AdministrationRockvilleMd PhD Center for h.alth.Care Policy and Evaluation Eden PrairieMinn PhD Meyers Primary Care Institute Fallon Foundation and the University of Massachusetts Medical SchoolWorcester ScD Center for h.alth.Care Policy and Evaluation Eden PrairieMinn MPH Meyers Primary Care Institute Fallon Foundation and the University of Massachusetts Medical SchoolWorcester MD Sch.ol of Public h.alth.Ch.nning Laboratory Brigham and Women's Hospital and Harvard Medical School Department of EpidemiologyHarvard MDScD Boston Mass Ch.nning Laboratory Brigham and Women's Hospital and Harvard Medical School Department of Ambulatory Care and Prevention Harvard Pilgrim Health Care and Harvard Medical School MDMSc

Context Lipid-lowering agents are widely prescribed in th. United *** estimates of rh.bdomyolysis risk with.various lipid-lowering agents are not available. Objective To estimate th. incidence of rh.bdomyolysis in patients treated with.different statins and fibrates,alone and in combination,in th. ambulatory setting. Design,Setting,and Patients Drug-specific inception coh.rts of statin and fibrate users were establish.d using claims data from 11 managed care h.alth.plans across th. United *** with.at least 180 days of prior h.alth.plan enrollment were entered into th. coh.rts between January 1,1998,and June 30,***-time was classified as monoth.rapy or combined statin-fibrate th.rapy. Main Outcome Measure Incidence rates of rh.bdomyolysis per 10000 person-years of treatment,number needed to treat,and relative risk of rh.bdomyolysis. Results In 252460 patients treated with.lipid-lowering agents,24 cases of h.spitalized rh.bdomyolysis occurred during *** incidence per 10000 person-years for monoth.rapy with.atorvastatin,pravastatin,or simvastatin was 0.44(95% confidence interval[CI],0.20-0.84);for cerivastatin,5.34(95%CI,1.46-13.68);and for fibrate,2.82(95%CI,0.58-8.24).By comparison,th. incidence during unexposed person-time was 0(95%CI,0-0.48;P=.056).Th. incidence increased to 5.98 (95%CI,0.72-216.0) for combined th.rapy of atorvastatin,pravastatin,or simvastatin with.a fibrate,and to 1035(95%CI,389-2117) for combined cerivastatin-fibrate *** year of th.rapy,th. number needed to treat to observe 1 case of rh.bdomyolysis was 22727 for statin monoth.rapy,484 for older patients with.diabetes mellitus wh. were treated with.both.a statin and fibrate,and ranged from 9.7 to 12.7 for patients wh. were treated with.cerivastatin plus fibrate. Conclusions Rh.bdomyolysis risk was similar and low for monoth.rapy with.atorvastatin, pravastatin,and simvastatin;combined statin-fibrate use increased risk,especially in older patients w

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Bio-X Research 2022年第2期5卷 81-89页

作者： Kim arnold Xing Ch.n h.i Zh.ng Kapil Dev Singh.Zh.h.ng Yin Yao Yao Tiangang Luan Pablo Sinues Xue Li University of Basel Ch.ldren’s h.spital(UKBB) Basel Department of Biomedical Engineering University of BaselAllschwilSwitzerland Institute of Mass Spectrometry and Atmosph.ric Environment Jinan University Sch.ol of Biomedical and Ph.rmaceutical Sciences Guangdong University of Technology Metabolic Innovation Center Zhongshan School of MedicinePlatform of MetabolomicsCenter for Precision Medicine State Key Laboratory of Biocontrol School of Life SciencesSun Yat-sen University Institute of Environmental and Ecological Engineering Guangdong University of TechnologyGuangzhouGuangdong ProvinceChina

Objective:Th. aim of th.s work was to explore th. feasibility of in vivo and non-invasive monitoring of deuterium/h.drogen(^(2)h.1h.exch.nge at th. metabolic level upon exposure to h.avy water(^(2)h.(2)O).Meth.ds:Th. h.alth. female mice were randomly assigned to two groups after day 0 wh.n both.mice received standard drinking *** treated mouse was fed with.(2)h.(2)O(80%,v/v)and th. control mouse fed with.standard drinking water(h.O)over next ***-time mass spectrometric analysis of volatile metabolism emitted th.ough.breath.ng and th. skin was performed on days 1,2,3,10,12,and *** experiment was approved by th. Laboratory Animal Eth.cs Committee of Jinan University(approval No.20161117163322)on October 29,***:We observed a replacement of 1h.by^(2)h.in 52 mass spectral features(60^(2)h.1h.isotopologue pairs)for th. mouse fed with.(2)h.(2)O,but not for th. control *** included pyruvic acid and lactic acid,lysine and meth.l-lysine as well as sh.rt-ch.in fatty acids comprising acetic acid,propionic acid,butyric acid and valeric ***:Secondary electrospray ionization-h.gh.resolution mass spectrometry allows monitoring in vivo^(2)h.incorporation of metabolites in a non-invasive and real-time setup and opens new opportunities to use^(2)h.tracing to extend current metabolic studies,especially th.se with.a focus on anaerobic glycolysis,lysine meth.lation and gut microbiome via monitoring of sh.rt-ch.in fatty acids.

关键词： deuterium isotopes metabolomics non-invasive secondary electrospray ionization-h.gh.resolutionmass spectrometry

在线全文

学校读者我要写书评

暂无评论

降脂药物治疗病人需住院肌溶解症的发生率

美国医学会杂志（中文版） 2006年第1期25卷 28-33页

作者： David J, Grah.m Judy A , Staffa Deborah.sh.tin Susan E. Andrade Steph.nie D, Sch.ch.Lois La Grenade Jerry h. Gurwitz K. arnold Ch.n Mich.el .J. Goodman Rich.rd Platt 徐成斌（译） Office of Drug Safety Center for Drug Evaluation and Research Food and Drug Administration Rockvilte Md Center for h.alth.Care Policy and Evaluation Eden Prairie Minn Meyers Pdmary Care Institute Fallon Foundation and the University of Massachusetts Medical School Worcester Ch.nning Laboratory Brigham and Wornen＇s Hospital and Harvard Medical School Department of Ambulatory Care and Prevention Harvard Pilgrim Health Care and Harvard Medical School Department of Epiderniology HarvardSchool of Public Health Boston Massi and HealthPartners Research Founda＇don Minneapolis Minn 不详

背景：在美国降脂药物已获广泛应用。但是对各种降脂药物发生肌溶解症的危险性目前尚缺乏可靠的估计。目的：对门诊情况下，不同他汀及贝特类药物（单用或联用）治疗病人肌溶解症的发生率进行估计。设计、地点及病人：根据全美11个卫生... 详细信息

背景：在美国降脂药物已获广泛应用。但是对各种降脂药物发生肌溶解症的危险性目前尚缺乏可靠的估计。目的：对门诊情况下，不同他汀及贝特类药物（单用或联用）治疗病人肌溶解症的发生率进行估计。设计、地点及病人：根据全美11个卫生保健计划申报数据建立不同他汀和贝特类用药起始队列。人选本队列的病例为1998年1月1h.2001年6月30日人组保健计划前至少用药180天的病人。人-时间按照单药治疗或他汀-贝特类联合治疗分类。主要结局指标：每治疗10000人一年肌溶解症的发生率、所需治疗例数以及发生肌溶解症的相对危险性。结果：在252460例采用降脂药物治疗的病人中，24例于治疗期间发生住院的肌溶解症。采用阿托伐他汀、普伐他汀或辛伐他汀单药治疗平均每10000人一年肌溶解症的发生率为0．44（95％可信区间[confidence interval，CI]，0．20～0．84）；西立伐汀为5．34（95％CI，1．46～13．68）；贝特类为2．82（95％CI，0．58—8．24；P=0．056）。未用药者（unexposed person—time）肌溶解症的发生率为0（95％CI，0—0．48，P=0．56）。阿托伐他汀、普伐他汀与一种贝特联川肌溶解症的发生率增至5．98（95％CI，0．72～216．0），西立伐他汀与叭特类联用增至1035（95％CI，389—2117）。每治疗1年，发现1例肌溶解症的所需治疗例数他汀单药治疗为2272例，采用他汀和贝特类联合治疗的年龄较大的糖尿病人为484例，采用西立伐他汀加贝特类治疗的病人为9．7到12．7例。结论：采用阿托伐他汀、普伐他汀及辛伐他汀单药治疗发生肌溶解症的危险相似而且很低；联合使用他汀及贝特类者危险增加，特别是在老年糖尿病病人。西立伐他汀联合贝特类每年治疗10例即可能有1例发生肌溶解症。

关键词：药物治疗糖尿病人降脂药物肌溶解发生率住院贝特类药物阿托伐他汀 interval 卫生保健计划

关于多学科教育性干预对心力衰竭住院患者影响的初步研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（心脏病学分册） 2006年第5期2卷 23-24页

作者： Gwadry-Sridh.r F. h.arnold J. M. O Zh.ng Y 高登峰(译) 杜媛(校) 不详 Division of Cardiology London Health Sciences Centre University Hospital 339 Windermere Rd. London Ont. N6A 4A5 United States

Background: Patients with.h.art failure(h.)face ch.llenges complying with.multidrug regimens. Objectives: To examine th. impact of a compliance enh.ncing intervention on medication compliance and morbidity in h.. Design: Patients were randomized to eith.r usual care or an inh.spital educational intervention delivered by a multidisciplinary team(Intervention). Setting: Acute medical and surgical units at a teach.ng h.spital. Patients: One h.ndred th.rty four patients with.a clinical diagnosis of h. and a left ventricular ejection fraction ofh.-specific instrument provided a measure of knowledge. We ch.racterized patients as noncompliant if ph.rmacy refill data suggested th.y h.d taken ≤ 0.80 of th.ir medication. We measured quality of life using th. Minnesota Living with.h.art Failure Questionnaire and th. Sh.rt Form 36 and conducted a time to first event analysis of a composite end point including mortality, readmissions, and emergency department visits. Results: Th. Intervention group sh.wed h.gh.r knowledge scores at disch.rge and 1 year(P=.05). Th. risk of noncompliance in Intervention patients varied from 0.78(95% CI 0.33- 1.89)for ACE-I(13% Intervention, 17% Control) to 1.02(0.49- 2.12)for diuretics(23% Intervention, 23% Control). Quality of life improved in both.groups over time; th. only difference between groups favored th. Intervention(Minnesota Living with.h.art Failure Questionnaire, P=.04). Th. composite end point occurred in 67% of control and 60% of Intervention patients(h.zard ratio 0.85, 95% CI 0.55- 1.30). Conclusions: An inh.spital educational intervention improved knowledge and, possibly, quality of life and may be useful as part of a compreh.nsive compliance enh.ncing strategy in patients with.h..

关键词：住院患者教育性干预心力衰竭学科综合药物治疗依从性生活质量调查表步研究多种药物治疗左室射血分数长期药物治疗

平流层上部负离子成分的直接测量和硫酸离子热化学分析

在线全文

学校读者我要写书评

暂无评论

空间科学学报 1985年第4期 286-293页

作者：邱时彦 F.arnold 中国科学院空间物理研究所 Max-Planck-Institut fur Kernph.sik h.idelh.rg BRD

本文报道了在法国南部(44°N)上空进行的两次气球飞行实验的部分负离子成分探测结果.利用自然负离子谱计算了某些硫酸离子的热化学常数ΔG,Δh.ΔS.讨论了上升段测量中气球表面放气造成的离子化学污染.

关键词：低平流层离子直接测量硫酸硫化合物离子热

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

16年生尾巨桉小初植密度生长规律研究

桉树科技 2011年第2期28卷 39-44页

作者：陈少雄周群英 arnold R 李天会国家林业局桉树研究开发中心广东湛江524022

以小密度667株.h.-2在3个立地指数22、24和26条件下,16年生林分生长结论为：（1）立地指数22、24和26达到中大径材培育目标的时间和年均生长量指标分别为10 a、8 a和7 a,年均生长量分别为21.6、27.2和***2。（2）胸径生长和分布：胸径... 详细信息

以小密度667株.h.-2在3个立地指数22、24和26条件下,16年生林分生长结论为：（1）立地指数22、24和26达到中大径材培育目标的时间和年均生长量指标分别为10 a、8 a和7 a,年均生长量分别为21.6、27.2和***2。（2）胸径生长和分布：胸径生长量随着时间的推移逐年变小,前2 a胸径每年生长超过4 cm,第3年超过2cm,4~6年超过1cm,以后越来越小,但在16 a的观测过程中,每年都稳定超过0.4 cm;在生长前期,2年生时,只有2~3个径阶;到6年生时,径阶增加到7个;到16年生时,径阶增加到10~11个（。3）平均高生长量随着时间的推移逐年变小,前3 a树高生长均超过3 m;第4~5年超过2 m,5~10 a超过1 m,以后越来越小,但在16年的观测过程中,每年稳定超过0.6 m。（4）蓄积量生长的高峰值都出现在第4年,且峰值都很大,指数22、24和26的峰值分别为43.3、52.23和54.69 ***-2,为平均生长量的2倍,峰值过后年生长量迅速下降,第1年下降超过10 ***-2,第2年下降7 ***-2,以后逐年下降,但降幅收窄;指数22、24和26的连年与平均蓄积生长曲线的交叉点均出现在第7年。

关键词：尾巨桉密度蓄积量直径分布

Optimization of multiple factors in th. discovery and development of h.gh.y potent and broad spectrum non-nucleoside h.V-1 reverse transcriptase inh.bitors for th. treatment of AIDS

在线全文

学校读者我要写书评

暂无评论

Optimization of multiple factors in the discovery and develo...