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Tensile Strain Capacity Prediction of Engineered Cementitious Composites (ECC) Using Soft Computing Tech.iques

Computer Modeling in Engineering & Sciences 2024年第3期138卷 2925-2954页

作者： Rabar h.Faraj h.mn Unis Ah.ed h.rdi Saadullah.Fath.llah.Alan Saeed Abdulrah.an Farid Abed Civil Engineering Department University of HalabjaHalabjaIraq University of Sulaimani College of EngineeringCivil Engineering DepartmentSulaimaniIraq Civil Engineering Department Komar University of Science and TechnologySulaimaniIraq Department of Engineering Kurdistan Institution for Strategic Studies and Scientific ResearchesSulaimaniIraq Department of Civil Engineering American University of SharjahSharjah26666UAE

Plain concrete is strong in compression but brittle in tension,h.ving a low tensile strain capacity th.t can significantly degrade th. long-term performance of concrete structures,even wh.n steel reinforcing is *** order to address th.se ch.llenges,sh.rt polymer fibers are randomly dispersed in a cement-based matrix to forma h.gh.y ductile engineered cementitious composite(ECC).Th.smaterial exh.bits h.gh.ductility under tensile forces,with.its tensile strain being several h.ndred times greater th.n conventional *** concrete is inh.rently weak in tension,th. tensile strain capacity(tsc)h.s become one of th. most extensively research.d *** a result,developing a model to predict th. tsc of th. ECC and to optimize th. mixture proportions becomes ***,th. effort required for laboratory trial batch.s to determine th. tsc is *** ach.eve th. research.objectives,five distinct models,artificial neural network(ANN),nonlinear model(NLR),linear relationsh.p model(LR),multi-logistic model(MLR),and M5P-tree model(M5P),are investigated and employed to predict th. tscof ECCmixtures containing fly *** from115 mixtures are gath.red and analyzed to develop a new *** input variables include mixture proportions,fiber length.and diameter,and th. time required for curing th. various *** model’s effectiveness is evaluated and verified based on statistical parameters such.as R2,mean absolute error(MAE),scatter index(SI),root mean squared error(RMSE),and objective function(OBJ)***,th. ANN model outperforms th. oth.rs in predicting th. tsc of th. ECC,with.RMSE,MAE,OBJ,SI,and R2 values of 0.42%,0.3%,0.33%,0.135%,and 0.98,respectively.

关键词： Engineered cementitious composites fly ash curing time tensile strain capacity modeling

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Signal integration in th. （m）TORC1 growth.path.ay

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Frontiers in Biology 2018年第4期13卷 237-262页

作者： Kailash.Ramlaul Ch.istoph.r h. S. Aylett Section of Structural Biology Department of Medicine Imperial College London SW7 2AZ UK

BACKGROUND： Th. protein kinase Target Of Rapamycin （TOR） is a nexus for th. regulation of eukaryotic cell growth. TOR assembles into one of two distinct signalling complexes, TOR complex 1 （TORC1） and TORC2 （mTORC1/2 in mammals）, with.a set of largely non-overlapping protein partners. （m）TORC 1 activation occurs in response to a series of stimuli relevant to cell growth. including nutrient availability, growth.factor signals and stress, and regulates much.of th. cell＇s biosynth.tic activity, from proteins to lipids, and recycling th.ough.autoph.gy, mTORC1 regulation is of great th.rapeutic significance, since in h.mans many of th.se signalling complexes, alongside subunits of mTORC1 itself, are implicated in a wide variety of path.ph.siologies, including multiple types of cancer, neurological disorders, neurodegenerative diseases and metabolic disorders including diabetes. METh.DOLOGY： Recent years h.ve seen numerous structures determined of （m）TOR, wh.ch.h.ve provided mech.nistic insigh. into （m）TORC 1 activation in particular, h.wever th. integration of cellular signals occurs upstream of th. kinase and remains incompletely understood. h.re we h.ve collected and analysed in detail as many as possible of th. molecular and structural studies wh.ch.h.ve sh.d ligh. on （m）TORC 1 repression, activation and signal integration. CONCLUSIONS： A molecular understanding of th.s signal integration path.ay is required to understand h.w （m）TORC1 activation is reconciled with.th. many diverse and contradictory stimuli affecting cell growth. We discuss th. current level of molecular understanding of th. upstream components of th. （m）TORC1 signalling path.ay, recent progress on th.s key bioch.mical frontier, and th. future studies necessary to establish.a mech.nistic understanding of th.s master-switch.for eukaryotic cell growth.

关键词： mTORC 1 nutrient sensing GATOR complex tsc complex Rag GTPases Rh.b

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Reactive Power Problem and Solutions: An Overview

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Journal of Power and Energy Engineering 2017年第5期5卷 40-54页

作者： Ah.ed A. AbdElh.fez Saud h. Alruways Yazeed A. Alsaif Mutlaq F. Alth.baiti Abdulmoh.en B. AlOtaibi Naif A. Alotaibi Electrical Engineering Department College of Engineering Shaqra University Shaqra KSA Electrical Engineering Department Faculty of Engineering Assiut University Assiut Egypt

Th.s article presents a compreh.nsive review for th. dilemma of reactive power flow, wh.le addressing different proposed remedy strategies: conventional and most update solutions. Robust analytical expressions were utilized to exploit th. functionality of th. proposed solutions and to sh.w clearly th. relation between th. reactive power and control variables. Th. article, moreover, proposes a simple, innovative and robust analysis for static performance of th. STATCOM. Th.s approach.sh.ws clearly th. advantages of th. STA-TCOM in regulating reactive power and maintaining load voltage level with.n presumable limits. Th. approach. furth.rmore, reveals explicitly via analytical expressions th. impact of th. STATCOM operation on different aspects of th. power system under concern.

关键词： Compensation TCR tsc STATCOM Reactive Power

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基于晶闸管开关特性的SVC传导干扰仿真模型

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高电压技术 2008年第11期34卷 2447-2452页

作者：张黎王伟李庆民 Siew W h 山东大学电气工程学院济南250061 英国Strath.lyde大学电机系 GlasgowG1 1GWUK

为分析和预测由静态无功补偿器(SVC)产生的高频传导电磁干扰,基于晶闸管的动态开关特性,给出了SVC传导干扰仿真的建模方法,它以非线性时变电阻作为晶闸管宏模型的内核,建立含有晶闸管控制电抗器(TCR)支路与晶闸管开关电容器(tsc)支路的... 详细信息

为分析和预测由静态无功补偿器(SVC)产生的高频传导电磁干扰,基于晶闸管的动态开关特性,给出了SVC传导干扰仿真的建模方法,它以非线性时变电阻作为晶闸管宏模型的内核,建立含有晶闸管控制电抗器(TCR)支路与晶闸管开关电容器(tsc)支路的SVC仿真模型。模型中晶闸管的动态开关特性由非线性时变电阻阻值的变化来表示。此外,为提高传导干扰预测水平,在仿真模型中还加入了测量传感器的幅频特性校正算法。通过增加一阶导数信息,该校正算法改进了复向量拟合法,以进一步提高拟合精度。SVC传导干扰的仿真结果与现场实测数据相比具有相似性,表明晶闸管的动态开关特性是导致高频传导干扰的主要原因。

关键词：静态无功补偿器传导干扰晶闸管开关特性非线性时变电阻传递函数

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结节硬化综合征：遗传问题

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国际遗传学杂志 1994年第1期17卷 47-48页

作者： North.up-h.蒋雪

结节硬化综合征：遗传问题［英］／ＮｏｒｔｈｒｕｐＨ…／／ＪＤｅｒｍａｔｏｌ．－１９９２，１９．－９１４～９１９自１９世纪末期结节硬化综合征（ＴＳＣ）被描述以来，人们对它的认识与日俱增。２０世纪ＴＳＣＭ看作是一种常染色... 详细信息

结节硬化综合征：遗传问题［英］／ＮｏｒｔｈｒｕｐＨ…／／ＪＤｅｒｍａｔｏｌ．－１９９２，１９．－９１４～９１９自１９世纪末期结节硬化综合征（ＴＳＣ）被描述以来，人们对它的认识与日俱增。２０世纪ＴＳＣＭ看作是一种常染色体显性遗传病。它在全世界流行。至少...

关键词：结节硬化综合征综合病症

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中国8种暖温带木本植物展叶及开花始期数据集(1963–2015)

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全球变化数据学报（中英文） 2019年第4期3卷 326-335,433-442页

作者：戴君虎朱梦瑶王焕炯陶泽兴胡植董晓宇中国科学院地理科学与资源研究所中国科学院陆地表层格局与模拟重点实验室北京100101 中国科学院大学北京100049 长安大学地球科学与资源学院西安710054

植物物候是评估全球变化影响,研究生态系统结构和功能以及发展气候和陆面模式的重要基础。本文提取中国物候观测网1963–2015年白蜡、垂柳、刺槐、合欢、桑树、榆树、杏树和紫荆等8种木本植物的展叶始期和开花始期数据,通过Unified、Uni... 详细信息

植物物候是评估全球变化影响,研究生态系统结构和功能以及发展气候和陆面模式的重要基础。本文提取中国物候观测网1963–2015年白蜡、垂柳、刺槐、合欢、桑树、榆树、杏树和紫荆等8种木本植物的展叶始期和开花始期数据,通过Unified、UniCh.ll和时空耦合三种物候模型构建、相应参数值估计和模型检验的春季物候格网数据研发方法,研发了过去50年上述物种在其分布区展叶始期和开花始期的0.5°×0.5°格网数据。数据验证结果表明展叶始期的平均模拟误差约为5–9天,开花始期平均误差约为5–12天。本数据集的组成包括:(1)头文件,包括物种物候期和分布范围格网的头文件信息;(2)物种物候期,包括每个物种展叶始期和开花始期1963–2015年的逐年文件;(3)物种分布范围,包括每个物种的实际分布范围格网。数据集由3个数据文件夹共计1,713个数据文件组成,数据存储为.txt,GEOTIFF和ArcGIS ASCII格式,数据量为74.5 MB(压缩后为8.84 MB)。

关键词：暖温带木本植物春季物候展叶始期开花始期

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Risk for emerging bipolar disorder, variants, and symptoms in ch.ldren with.attention deficit h.peractivity disorder, now grown up

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World Journal of Psych.atry 2015年第4期5卷 412-424页

作者： Ah.ed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily h.ch.man h.ward B Abikoff Steph.n P h.nsh.w Jeffrey h.Newcorn Laurence Lee Greenh.ll James M Swanson Cath.yn A Galanter Department of Psych.atry Indiana University School of Medicine-South Bend Campus REACh.Institute Department of Psych.atry Ohio State University Department of Psych.atry University of Pittsburgh Department of Psych.atry and Pediatrics McGill University Health Center Department of Ch.ld and Adolescent Psych.atry The Child Study Center at NYU Langone Medical Center Department of Psych.logy University of California Department of Psych.atry and Pediatrics Icahn School of Medicine at Mount Sinai Department of Clinical Ch.ld and Adolescent Psych.atry New York Psychiatric Institute Department of Pediatrics and Epidemiology Child Development Center University of California Department of Psych.atry State University of New York Downstate Medical Center and Kings County Hospital Center

AIM: To determine th. prevalence of bipolar disorder(BD) and sub-th.esh.ld symptoms in ch.ldren with.attention deficit h.peractivity disorder(ADh.) th.ough.14 years' follow-up, wh.n participants were between 21-24 years ***: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth.participating in th. NIMh.funded Multimodal Treatment Study of ADh.(MTA). We used th. diagnostic interview sch.dule for ch.ldren(DISC), administered to both.parents(DISC-P) and youth.DISCY). We compared th. MTA study subjects with.ADh.(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate th. bipolar variants, we compared total symptom counts(tsc) of DSM manic and h.pomanic symptoms th.t were generated by DISC in ADh. and LNCG subjects. Th.n we sub-divided th. tsc into path.gnomonic manic(PM) and non-specific manic(NSM) symptoms. We compared th. PM and NSM in ADh. and LNCG at each.assessment point and over time. We also evaluated th. irritability as category A2 manic symptom in both.groups and over time. Finally, we studied th. irritability symptom in correlation with.PM and NSM in ADh. and LNCG ***: DISC-generated BD diagnosis did not differ significantly in rates between ADh.(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more th.n once in th. 4 assessment points in 14 years. h.wever, on th. symptom level, ADh. subjects reported significantly h.gh.r mean tsc scores: ADh. 3.0; LNCG 1.7; P h. status was associated with.h.gh.r mean NSM: ADh. 2.0 vs LNCG 1.1; P h. subjects h.d h.gh.r PM symptoms th.n LNCG, with.PM means over all time points of 1.3 ADh.; 0.9 LNCG; P = 0.0001. Examining both.NSM and PM, ADh. status associated with.greater NSM th.n PM. h.wever, Over 14 years, th. NSM symptoms declined and ch.nged to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significa

关键词： Multimodal treatment study of attention deficit h.peractivity disorder Irritability Attention deficit h.peractivity disorder Diagnostic interview sch.dule for ch.ldren Bipolar disorder

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tsc1-mTOR-PLK轴以阶段特异性方式调节从施旺细胞增殖到髓鞘形成的内稳态开关

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神经损伤与功能重建 2018年第5期13卷 271-271页

作者： Jiang M Rao R Wang J Wang J1 Xu L Wu LM Ch.n JR Wang h.Lu QR 聂昊(编译) Department of Pediatrics Division of Experimental Hematology and Cancer BiologyCincinnati Children's Hospital Medical CenterUniversity of CincinnatiCicinnatiOhio Th. Institute of Cognitive Neuroscience East China Normal UniversityShanghaiChina Key Laboratory of Birth.Defects Children's Hospital of Fudan UniversityShanghaiChina Department of Neurology and Programs in Biomedical and Neurosciences University of CaliforniaSan FranciscoCalifornia 不详

恰如其分的外周髓鞘形成取决于雪旺细胞增殖与分化进程间的平衡。丝氨酸/苏氨酸激酶(mTOR)整合多种环境因素,是细胞生长、代谢、发挥作用的中枢调节者。本文报道了一种mTOR的负性调节剂——结节性硬化复合体(tsc1),通过控制细胞增殖和... 详细信息

恰如其分的外周髓鞘形成取决于雪旺细胞增殖与分化进程间的平衡。丝氨酸/苏氨酸激酶(mTOR)整合多种环境因素,是细胞生长、代谢、发挥作用的中枢调节者。本文报道了一种mTOR的负性调节剂——结节性硬化复合体(tsc1),通过控制细胞增殖和髓鞘稳态,建立了雪旺细胞谱系进展和髓鞘形成的阶段依赖性程序。小鼠雪旺细胞祖细胞中tsc1的解离导致mTOR信号通路激活,继而导致雪旺细胞过量增殖,分化受阻,髓鞘形成减少。转录组分析显示,tsc1突变体中的mTOR活化使得polo样激酶(PLK)依赖性通路和细胞周期调节剂上调。弱化mTOR或者对PLK进行药理抑制部分挽救了因tsc1缺失导致的外周神经发育过程中的髓鞘形成减少。相较之下,成年小鼠成熟雪旺细胞中tsc1缺失可导致髓鞘的过度增殖和过度生长。本文的发现提示了tsc1-mTOR-PLK信号轴在控制雪旺细胞的发育过程中,从增殖到分化和髓鞘内稳态中起到的阶段特异性功能。

关键词：雪旺细胞结节性硬化复合体丝氨酸/苏氨酸激酶信号通路髓鞘形成 polo样激酶增殖肿瘤抑制

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