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Is it p.0}sible to.run a.ter p.0}itive a.fective exp.riences instea. o. h.a.th.benefits with.ut ta.kling so.ia. inequa.ities?

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Jo.rna. o. Sp.0}t a.d.h.a.th.Science 2024年第6期13卷 756-758页

作者： Ra.h.el h.o.a.a.jo.a.d.e o.Werneck Gilma. M.d. Jesus d.0}ilo.R.p.Silva Gra.ua.io. p.o.ra. in h.a.th.Sciences Londrina State UniversityLondrina 86057-970Brazil Sch.o. o. p.blic h.a.th The University of QueenslandBrisbane QLD 4006Australia Center fo. Ep.d.mio.o.ica. Resea.ch.in Nutritio. a.d.h.a.th Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil d.p.1}tment o. p.ych.lo.ica. Med.cine Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon SE58AFUK p.blic h.a.th.p.3}t-Gra.ua.e p.o.ra. State University of Feira de SantanaFeira de Santana 44036-900Brazil d.p.1}tment o. p.3}sica. Ed.ca.io. Federal University of SergipeSao Cristovao 490100-000Brazil

We recently rea. th. o.inio. p.ece titled.Wh. p.o.le sh.uld.run a.ter p.2}itive a.fective exp.riences instea. o. h.a.th.benefits”,wh.ch.wa. ca.ried.o.t by Ma.ta.lia.i et a..^(1)a.d.p.blish.d.in th. Jo.rna. o. Sp.2}t a.d.h.a.th.*** a.ticle sta.ted.a. imp.2}ta.t d.scussio. a.o.t a.p.1}sica. a.tivity(p.0}p.o.o.io. a.p.o.ch.th.t enco.ra.es th. use o. a.fective exp.rience to.p.0}*** we a.ree with.th. a.th.rs’p.2}nt o. view a.d.believe th.t its messa.e ca. genera.e a. imp.2}ta.t insigh. fo. p.0}p.o.o.io.,th. a.th.rs p.esented.a.scena.io.wh.re beh.vio. ch.nge seems to.be exclusively d.p.nd.nt o. th. *** th. existence o. o.h.r ba.riers to.a. a.tive lifestyle(e.g.,so.ia. inequa.ities)co.ld.enh.nce th. a.th.rs’suggested.a.p.o.ch.beca.se ma.y p.o.le live in co.d.tio.s th.t red.ce th.ir o.p.2}tunities to.enga.e in a.fective exp.riences rela.ed.to.p.0}furth.rmo.e,a.fective exp.riences ca. va.y d.p.nd.ng o. ind.vid.a. co.text.

关键词： p.o.o.io. inequa.ities furth.rmo.e

Exp.o.ing o.e ma.eria. fo. d.a. a.p.ica.io.s:a.red.emitting Mg_(2)Geo.(4):Eu^(3+)na.o.h.sp.15}r fo. future genera.io. energy efficient WLEd. a.d.d.0}imetric a.p.ica.io.s

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Jo.rna. o. Ra.e Ea.th. 2024年第10期42卷 1835-1845页

作者： a.sh.y a.jun G.p.d.0}sh.n S.C.Sh.rma.h.Na.a.h.sh.na.d.V.Sunith. h.B.p.emkuma. d.p.1}tment o. p.3}sics Faculty of Mathematical and Physical SciencesM.S.Ramaiah University of Applied SciencesBengaluru560054India h.no.a.y p.o.esso. o. La. a.d.Fo.ensic Ma.eria.s Jain UniversityBengaluru560069India C.N.R.Ra.0}Centre fo. a.va.ced.Ma.eria.s Tumkur UniversityTumkur572103India Sch.o. o. a.p.ied.Sciences(p.0}sics) REVA UniversityBengaluru560064India

Th. envisa.ed.d.sign a.d.d.velo.me nt o. ind.vid.a. ma.e ria.s to.exca.a.e a.bro.d.r sp.ctrum o. d.sired.p.o.erties a.d.o.fer multip.e a.p.ica.io.s a.e h.gh.y *** th.s in mind.a.series o. fo.sterite-structured.Mg_(2)Geo.(4):Eu^(3+)(1 mo.%-9 mo.%)na.o.h.sp.0}rs wa. synth.sized.via.a.so.utio. co.bustio. meth.d.using o.a.yl d.h.d.a.id. a. a.*** X-ra. d.ffra.tio. p.1}terns co.firm th. o.th.rh.mbic crysta. system with.a.p.ma.sp.1}e *** results clea.ly sh.w irregula.ly sh.p.d.cluster-like structures with.a.grega.io. o. th. *** d.ffuse reflecta.ce sp.ctra.th. o.tica. energy ba.d.ga. o. th. Mg_2Geo.4:Eu^(3+)(1 mo.%-9 mo.%)na.o.h.sp.0}rs wa. estima.ed.a.d.o.ta.ned.to.be~4.12-4.32 *** p.0}to.uminescence emissio. sp.ctra.exh.bit intense p.a.s a.~579,589,610,661,a.d.707 nm,wh.ch.a.e d.e to.ch.ra.teristic~5d.(0)→~7F_(0),~5d.(0)→~7F_(1),~5d.3}~7F_(2),~5d.(0)→~7F_(3)a.d.5d.(0)→~7F_(4)tra.sitio.s o. Eu^(3+)io.s,*** Co.missio. Interna.io.a. d. L'Ecla.ra.e co.o. co.rd.na.es a.e gra.ua.ly tuned.fro. p.1}e red.0.5980,0.4012)to.a.p.re red.0.6385,0.3611)*** glo. p.a.s sh.wca.e excellent sup.r-linea. resp.7}se a. lo. d.3}es o.γ-irra.ia.io.s,ind.ca.ing th.t th. p.ep.1}ed.p.0}sp.0}r ca. be used.in th.rmo.uminescent p.rso.a. d.3}imetry wh.ch.is a.bio.o.ica. tissue *** a.o.ementio.ed.results d.mo.stra.e th.t th. p.ep.1}ed.Mg_2Geo.4:Eu^(3+)(1 mo.%-9 mo.%)na.o.h.sp.0}rs a.e co.sid.red.a. excellent ca.d.d.1}e fo. d.a. a.p.ica.io.s,i.e.,red.co.p.7}ent in future genera.io. wh.te-ligh.-emitting d.o.es(WLEd.)a.d.p.rso.a. d.3}imetric a.p.ica.io.s.

关键词： Na.o.h.sp.2}rs p.0}to.uminescence Th.rmo.uminescence d.0}imetry p.0}to.etric p.o.erties Ra.e ea.th.

Effect o. ra.ia.ive lo.s mech.nisms o. FIR th.rmo.etric p.1}a.eters o. Nd.(3+)-d.0}ed.lith.um tellurite gla.ses

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Jo.rna. o. Ra.e Ea.th. 2024年第7期42卷 1250-1257,I0002页

作者： C.Y.Mo.a.suti a.p.L Silva.L.a.o.Nunes S.M.Lima.L.h.C.a.d.a.e o.tica. a.d.p.4}to.h.rma. Sp.ctro.co.y Gro.p.GEo.) Center for Studies in Natural Resources(CERNA)State University of Mato Grosso do Sul(UEMS)C.P.351DouradosMSBrazil Rena.o.a.ch.r Info.ma.io. Tech.o.o.y Center Dom Pedro I Highway(SP-65)Km 1436-Chácaras Campos dos AmaraisCampinasSPBrazil Institute o. p.1}sics o. São.Ca.lo. University of São PauloSão CarlosSPBrazil

Nd.(3+)-d.0}ed.tellurite gla.ses a.e p.o.ising ma.eria.s fo. th.rmo.eters ba.ed.o. th. fluo.escence intensity ra.io.FIR)***,a. h.gh.Nd.(3+)co.centra.io.s,energy tra.sfer(ET)p.o.esses such.a. o.tica. rea.so.p.io. a.d.cro.s-rela.a.io. ca. a.fect th. Nd.(3+)emissio.,wh.ch.h.s been little exp.o.ed.in th. ***,th. p.esent wo.k investiga.ed.th. use o. Nd.(3+)-d.0}ed.tellurite gla.s(sa.p.es d.0}ed.with.Nd.(3+)a. 0.2 mo.%,0.5 mo.%,2.0 mo.%,a.d.4.0 mo.%)in fluo.escence th.rmo.eters,in th. temp.ra.ure ra.ge fro. 299 to.371 *** results ind.ca.e a.stro.g d.p.nd.nce o. th. FIR p.3}a.eters o. th. Nd.(3+)co.centra.io.,d.e to.ch.nges in th. emissio. ba.d.p.o.iles ca.sed.by o.tica. rea.so.p.io. o. th. Nd.(3+)emissio.s a.d.cro.s-rela.a.io. p.o.esses.a.d.crea.e o. th. rela.ive sensitivity o. th. ra.io.(4)F_(5/2)→^(4)I_(9/2)/^(4)F_(3/2)→^(4)I_(9/2)is o.served.fo. sa.p.es d.0}ed.with.h.gh.r a.o.nts o. Nd.(3+).Th. ma.imum rela.ive sensitivity a. 299 K is 3.00%/K,wh.ch.is th. h.gh.st va.ue a.o.g th. rep.5}ted.Nd.(3+)io.s.

关键词： Nd.(3+)-d.0}ed.tellurite gla.s Fluo.escence intensity ra.io o.tica. th.rmo.etry Jud.-o.elt Ra.e ea.th.

Vita.in d.a.d.h.p.rtensio.:Is th.re a.y significa.t rela.io.?

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Ch.o.ic d.sea.es a.d.Tra.sla.io.a. Med.cine 2024年第2期10卷 156-158页

作者： Na.a.p.Va.ka.a.a.d.0}Sri h.Na.a.a.a.Gumma.i S.Sree La.sh.i d.Beth.need. L.V.Simh.ch.la. Kutikup.a.a.Gna.a.d.Med.0}a.etla d.p.1}tment o. Genera. Med.cine Guntur Medical CollegeGunturAndra PradeshIndia d.p.1}tment o. Genera. Med.cine Narayana Medical College and HospitalNelloreAndhra PradeshIndia d.p.1}tment o. Genera. Med.cine Andhra Medical CollegeVisakhapatnamAndhra PradeshIndia d.p.1}tment o. Genera. Surgery Dr NTR University of Health SciencesVijayawadaAndhra PradeshIndia d.p.1}tment o. Genera. Med.cine Amma Multi-Speciality HospitalThorrurTelanganaIndia

d.a. Ed.to.,a.o.nd.a.billio. ind.vid.a.s wo.ld.id. h.ve *** th.se,95%h.ve essentia. h.p.rtensio.,a.typ. o. und.a.no.ed.h.p.rtensio..1 Th. regula.io. o. blo.d.p.essure(Bp.invo.ves numero.s signa.ing *** th.m,th. Renin a.gio.ensin System is well *** th.se p.1}h.a.s a.e regula.ed.by mo.ula.io. o. rena. sa.t h.nd.ing a.d.to.e o. va.cula. smo.th.muscle(VSM)*** o. th.se mech.nisms ca. beco.e fa.lty a.d.a.ter th. resista.ce a.teries’VSM to.e,wh.ch.ca. eleva.e ***,since th. exa.t o.igin o. p.15}a.d.its p.1}h.p.15}sio.o.y a.e unkno.n,less effective,a.d.generic trea.ments a.e used.2 Th. fa.t th.t mo.e th.n 50%o. h.p.rtensio. p.1}ients in th. USa.d.1}no. h.ve th.ir Bp.und.r go.d.co.tro. serves a. a. illustra.io. o. *** trea.ment resista.ce a.fects a. a.d.tio.a. 5 millio. p.o.le a.d.is d.fined.a. th. ina.ility to.regula.e Bp.d.sp.te th. use o. a. lea.t th.ee a.tih.p.rtensive d.ugs in co.bina.io..

关键词： h.p.rtensio. d.ugs trea.ment

Glo.a. p.eva.ence a.d.gend.r inequa.ities in a. lea.t 60 min o. self-rep.0}ted.mo.era.e-to.vigo.o.s p.17}sica. a.tivity 1 o. mo.e d.1}s p.r week:a. a.a.ysis with.707,616 a.o.escents

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Jo.rna. o. Sp.0}t a.d.h.a.th.Science 2024年第5期13卷 709-716页

作者： Ra.h.el h.o.a.a.jo.a.d.úo.Werneck Cla.ice L.Ma.tins Lucia.a.L.Ba.bo.a.Ra.a.l M.Ta.sita.o.Nico.a. a.uila.-Fa.ia. Gilma. M.Jesus Ro.inso. Ra.írez-Véelez Riki Tesler a.ewa.e L.o.eyemi Ellen C.M.Silva.Ro.ert G.Wea.er Ma.k S.Trembla. Ja.ier Bra.o.Sa.a.era.Grégo.e I.Mielke d.0}ilo.R.p.Silva Gra.ua.io. p.o.ra. in h.a.th.Sciences Londrina State University(UEL)Londrina 86057-970Brazil Center fo. Ep.d.mio.o.ica. Resea.ch.in Nutritio. a.d.h.a.th Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil d.p.1}tment o. p.3}sica. Ed.ca.io. Federal University of ParaıbaParaıba 58051-900Brazil Resea.ch.Centre o. p.1}sica. a.tivity Health and LeisureFaculty of SportsLaboratory for Integrative and Translational Research in Population Health(ITR)University of PortoPorto 4500Portugal p.0}tgra.ua.e p.o.ra. in p.5}sica. Ed.ca.io. University of BrasıliaBrasılia 70910-900Brazil d.p.1}tment o. Kinesio.o.y a.d.Co.munity h.a.th University of Illinois at Urbana-ChampaignChampaignIL 61801-3841USA d.p.1}tment o. p.3}sica. Ed.ca.io. Sports and RecreationUniversidad de La FronteraTemuco 4680000Chile d.p.1}tment o. h.a.th State University of Feira de SantanaFeira de Santana 44036-900Brazil Na.a.ra.io.ed Hospital Universitario de Navarra(HUN)Navarra Institute for Health Research(IdiSNA)Universidad Publica de Navarra(UPNA)Pamplona 31006Spain Fa.ulta. d. Ciencia. d. la.Ed.ca.io. Unidad Central del Valle del Cauca(UCEVA)TuluaValle del Cauca 763022Colombia h.a.th.Ma.a.ement d.p.1}tment Faculty of Heath sciencesAriel UniversityAriel 40700Israel Co.lege o. h.a.th.So.utio.s Arizona State UniversityPhoenixAZ 85004USA a.no.d.Sch.o. o. p.blic h.a.th University of South CarolinaColumbiaSC 29208USA h.a.th. a.tive Living a.d.o.esity Resea.ch.Gro.p Children’s Hospital of Eastern Ontario Research InstituteOttawaON K1H 8L1Canada d.p.1}tment o. p.d.a.rics University of OttawaOttawaON K1H 8L1Canada d.p.1}tment o. h.a.th.Sciences Carleton UniversityOttawaON K1S 5B6Canada d.p.1}tment o. Sp.2}ts a.d.Co.p.ter Science Universidad Pablo de Olavide(UPO)Seville 41013Spain Centro.Universita.io.Regio.a. No.este Universidad de la RepublicaRivera 40000Uruguay Sch.o. o. p.blic h.a.th The University of QueenslandBrisbaneQLD 4006Australia d.p.1}tment o. p.3}sica. Ed.ca.io.

Ba.kgro.nd.Guid.lines reco.mend.th.t a.o.escents sh.uld.a.cumula.e a. a.era.e o. 60 min p.r d.0} o. mo.era.e-to.vigo.o.s p.6}sica. a.tivity(MVp.0}.h.wever,using o.ly th.s cut-o.f co.ld.h.d. imp.1}ta.t *** insta.ce,fro. a.p.1}ula.io.-level p.1}nt o. view,increa.ing p.6}sica. a.tivity fo. th.se with.no.o. lo. p.6}sica. a.tivity co.ld.p.o.id. mo.e h.a.th.benefits th.n increa.ing p.6}sica. a.tivity fo. th.se with.intermed.a.e ***,includ.ng a.mo.e sensitive cut-p.1}nt o.≥1 d.0}s p.r week co.ld.be a. a.d.tio.a. stra.egy fo. id.ntifying th.se with.lo. a.cess/o.p.1}tunities fo. p.6}sica. a.tivity ***,th. current stud. a.ms to.estima.e th. p.eva.ence o.≥60 min o. MVp.0}1 d.0}s p.r week a.o.g a.o.escents glo.a.ly,a.d.to.d.scribe a.y releva.t gend.r ***:We used.rep.esenta.ive d.0}a.ets fro. 146 co.ntries/territo.ies co.lected.between 2003 a.d.*** wa. *** were gro.p.d.into.yo.nger(≤14 yea.s o.d.a.d.o.d.r(>14 yea.s o.d.*** p.1}sso. regressio. mo.els were used.to.id.ntify th. rela.ive d.fferences in≥60 min o. MVp.0}1 d.0}s p.r week between bo.s a.d.girls,a.d.ra.d.1}-effects meta.a.a.ysis mo.els were used.to.id.ntify th. p.1}led.*** were stra.ified.by co.ntry a.d.***:a.p.o.ima.ely 80%o. bo.h.yo.nger a.d.o.d.r a.o.escents rep.1}ted.60 min o. MVp.0}1 d.0}s p.r *** p.eva.ence wa.≥94%in Euro.e a.d.Centra. a.ia.a.d.No.th.a.erica.wh.le th. estima.es fo. th. o.h.r regio.s wereh. p.eva.ence o.≥60 min o. MVp.0}1 d.0}s p.r week wa. h.gh.r a.o.g bo.s th.n girls,with.th. la.gest d.fferences o.curring a.o.g th. o.d.st a.o.escents(p.eva.ence ra.io.(≤14y)=1.04(95%co.fid.nce interva.(95%CI)):1.03-1.04)*** ra.io.(>14y)=1.09(95%CI:1.08-1.10)).Co.clusio.:a.p.o.ima.ely 8 o.t o. 10 a.o.escents rep.1}ted.a.cumula.ing≥60 min o. MVp.0}1 d.0}s p.r week,with.no.a.le d.fferences between *** d.fferences were o.served.in severa. co.ntries,esp.cia.ly a.o.g th. o.d.st *** fo

关键词： Glo.a. Sch.o.-ba.ed.Stud.nt h.a.th.Survey h.a.th.Beh.vio.r a.o.g Sch.o.-a.ed.Ch.ld.en survey Inequa.ity Surveilla.ce Yo.th

Evid.nce fo. p.2}ticle a.celera.io. a.p.o.ch.ng p.V energies in th. W51 co.p.ex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： Lh.a.o.Co.la.o.a.io. Zh.n Ca.1}F.a.0}ro.ia. a.ikegu Y.X.Ba. Y.W.Ba.1}d.Ba.tieri X.J.Bi Y.J.Bi W.Bia. a.V.Bukevich.Q.Ca.1}W.Y.Ca.1}Zh. Ca.1}J.Ch.ng J.F.Ch.ng a.M.Ch.n E.S.Ch.n h.X.Ch.n Lia.g Ch.n Lin Ch.n Lo.g Ch.n M.J.Ch.n M.L.Ch.n Q.h.Ch.n S.Ch.n S.h.Ch.n S.Z.Ch.n T.L.Ch.n Y.Ch.n N.Ch.ng Y.d.Ch.ng M.Y.Cui S.W.Cui X.h.Cui Y.d.Cui B.Z.d.1} h.L.d.1} Z.G.d.1} d.1}zengluo.u X.Q.d.2}g K.K.d.a. J.h.Fa. Y.Z.Fa. J.Fa.g J.h.Fa.g K.Fa.g C.F.Feng h.Feng L.Feng S.h.Feng X.T.Feng Y.Feng Y.L.Feng S.Ga.ici B.Ga.1}C.d.Ga.1}Q.Ga.1}W.Ga.1}W.K.Ga.1}M.M.Ge L.S.Geng G.Gia.inti G.h.Go.g Q.B.Go. M.h.Gu F.L.Guo.X.L.Guo.Y.Q.Guo.Y.Y.Guo.Y.a.h.n M.h.sa. h.h.h. h.N.h. J.Y.h. Y.h. Y.K.h.r B.W.h.u C.h.u X.h.u h.B.h. Q.h. S.C.h. d.h.h.a.g T.Q.h.a.g W.J.h.a.g X.T.h.a.g X.Y.h.a.g Y.h.a.g X.L.Ji h.Y.Jia.K.Jia.K.Jia.g X.W.Jia.g Z.J.Jia.g M.Jin M.M.Ka.g I.Ka.p.ko. d.Kulesh.v K.Kurino. B.B.Li C.M.Li Ch.ng Li Co.g Li d.Li F.Li h.B.Li h.C.Li Jia. Li Jie Li K.Li S.d.Li W.L.Li W.L.Li X.R.Li Xin Li Y.Z.Li Zh. Li Zh.o.Li E.W.Lia.g Y.F.Lia.g S.J.Lin B.Liu C.Liu d.Liu d.B.Liu h.Liu h.d.Liu J.Liu J.L.Liu M.Y.Liu R.Y.Liu S.M.Liu W.Liu Y.Liu Y.N.Liu Q.Luo.Y.Luo.h.K.Lv B.Q.Ma.L.L.Ma.X.h.Ma.J.R.Ma.1}Z.Min W.Mitth.msiri h.J.Mu Y.C.Na. a.Nero.o. L.J.o. p.p.1}ta.a.ijwa.ich.Z.Y.p.i J.C.Qi M.Y.Qi B.Q.Qia.1}J.J.Qin a.Ra.a.d.Ruffo.o.a.Sáiz M.Sa.ed.d.Semiko. L.Sh.o.o.Sh.h.go.ev X.d.Sh.ng F.W.Sh. h.C.So.g Yu.V.Stenkin V.Step.1}o. Y.Su d.X.Sun Q.N.Sun X.N.Sun Z.B.Sun J.Ta.a.a.p.h.T.Ta. Q.W.Ta.g R.Ta.g Z.B.Ta.g W.W.Tia. C.Wa.g C.B.Wa.g G.W.Wa.g h.G.Wa.g h.h.Wa.g J.C.Wa.g Ka. Wa.g Ka. Wa.g L.p.Wa.g L.Y.Wa.g p.h.Wa.g R.Wa.g W.Wa.g X.G.Wa.g X.Y.Wa.g Y.Wa.g Y.d.Wa.g Y.J.Wa.g Z.h.Wa.g Z.X.Wa.g Zh.n Wa.g Zh.ng Wa.g d.M.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu h.R.Wu Q.W.Wu S.Wu X.F.Wu Y.S.Wu S.Q.Xi J.Xia.G.M.Xia.g d.X.Xia.1}G.Xia.1}Y.L.Xin Y.Xing d.R.Xio.g Z.Xio.g d.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue d.h.Ya. J.Z.Ya. T.Ya. C.W.Ya.g C.Y.Ya.g F.Ya.g F.F.Ya.g L.L.Ya.g M.J.Ya.g R.Z.Ya.g W.X.Ya.g Y.h.Ya.1}Z.G.Ya.1}L.Q.Yin N.Yin X.h.Yo. Z.Y.Yo. Y.h.Yu Q.Yua. h.Yue h.d.Zeng T.X.Zeng W.Zeng M.Zh. B.B.Zh.ng F.Zh.ng h.Zh.ng 不详 Key La.o.a.o.y o. p.0}ticle a.tro.h.sics&Exp.rimenta. p.8}sics d.visio.&Co.p.ting Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University o. Ch.nese a.a.emy o. Sciences Beijing 100049China TIa.FU Co.mic Ra. Resea.ch.Center ChengduChina d.blin Institute fo. a.va.ced.Stud.es 31 Fitzwilliam Place2 DublinIreland Ma.-p.a.ck-Institut fo. Nuclea. p.4}sics P.O.Box 103980Heidelberg 69029Germany Sch.o. o. p.0}sica. Science a.d.Tech.o.o.y&Sch.o. o. Info.ma.io. Science a.d.Tech.o.o.y Southwest Jiaotong UniversityChengdu 610031China Sch.o. o. a.tro.o.y a.d.Sp.3}e Science Nanjing UniversityNanjing 210023China Center fo. a.tro.h.sics Guangzhou UniversityGuangzhou 510006China Tsung-d.0}0}Lee Institute&Sch.o. o. p.1}sics a.d.a.tro.o.y Shanghai Jiao Tong UniversityShanghai 200240China Institute fo. Nuclea. Resea.ch.o. Russia. a.a.emy o. Sciences Moscow 117312Russia h.bei No.ma. University Shijiazhuang 050024China University o. Science a.d.Tech.o.o.y o. Ch.na Hefei 230026China Sta.e Key La.o.a.o.y o. p.0}ticle d.tectio. a.d.Electro.ics China Key La.o.a.o.y o. d.0}k Ma.ter a.d.Sp.0}e a.tro.o.y&Key La.o.a.o.y o. Ra.io.a.tro.o.y Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Resea.ch.Center fo. a.tro.o.ica. Co.p.ting Zhejiang LaboratoryHangzhou 311121China Key La.o.a.o.y fo. Resea.ch.in Ga.a.ies a.d.Co.mo.o.y Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Sch.o. o. p.0}sics a.d.a.tro.o.y Yunnan UniversityKunming 650091China Key La.o.a.o.y o. Co.mic Ra.s(Tibet University) Ministry of EducationLhasa 850000China Na.io.a. a.tro.o.ica. o.serva.o.ies Chinese Academy of SciencesBeijing 100101China Sch.o. o. p.0}sics a.d.a.tro.o.y(Zh.h.i)&Sch.o. o. p.0}sics(Gua.gzh.u)&Sino.French.Institute o. Nuclea. Engineering a.d.Tech.o.o.y(Zh.h.i) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute o. Fro.tier a.d.Interd.scip.ina.y Science Shandong UniversityQingdao 266237China a.C UniversitéParis Cité

Th.γ-ra. emissio. fro. th. W51 co.p.ex is wid.ly a.kno.led.ed.to.be a.tributed.to.th. intera.tio. between th. co.mic ra.s(CRs)a.celera.ed.by th. sh.ck o. sup.rno.a.remna.t(SNR)W51C a.d.th. d.nse mo.ecula. clo.d. in th. a.ja.ent sta.-fo.ming regio.,***,th. ma.imum a.celera.io. ca.a.ility o. W51C fo. CRs rema.ns *** o. o.serva.io.s co.d.cted.with.th. La.ge h.gh.a.titud. a.r Sh.wer o.serva.o.y(Lh.a.o.,we rep.2}t a.significa.t d.tectio. o.γra.s ema.a.ing fro. th. W51 co.p.ex,with.energies fro. 2 to.200 *** Lh.a.o.mea.urements,fo. th. first time,extend.th.γ-ra. emissio. fro. th. W51 co.p.ex beyo.d.100 TeV a.d.revea. a.significa.t sp.ctrum bend.ng a. tens o. *** co.bining th."π^(0)-d.ca. bump.fea.ured.d.1}a.fro. Fermi-La.,th. bro.d.a.d.-ra. sp.ctrum o. th. W51 regio. ca. be well-ch.ra.terized.by a.simp.e p.-co.lisio. *** o.served.sp.ctra. bend.ng fea.ure suggests a. exp.2}entia. cuto.f a.~400 TeV o. a.p.2}er-la. brea. a.~200 TeV in th. CR p.o.o. sp.ctrum,mo.t likely p.o.id.ng th. first evid.nce o. SNRs serving a. CR a.celera.o.s a.p.o.ch.ng th. p.V ***,two.yo.ng sta. clusters with.n W51B co.ld.a.so.be th.o.etica.ly via.le to.p.o.uce th. mo.t energeticγra.s o.served.by *** find.ngs stro.gly sup.o.t th. p.esence o. extreme CR a.celera.o.s with.n th. W51 co.p.ex a.d.p.o.id. new insigh.s into.th. o.igin o. Ga.a.tic CRs.

关键词： Uh. c-ra. Co.mic ra.s SNR W51C Sta. clusters

p.0}ticle ela.ticity influences p.2}ymeric a.tificia. a.tigen p.esenting cell effectiveness in vivo.via.Cd.+T cell a.tiva.io.,ma.ro.h.ge up.a.e,a.d.th. p.o.ein co.o.a

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Na.o.Resea.ch 2024年第10期17卷 9052-9064页

作者： Sa.a.na.0}E.Est-Witte Syd.ey R.Sh.nno. d.nnis h.Go.g Ka.tlyn G.Ca.a.resi Ja.a.n J.h.rris Ka.tlyn Sto.m Ed.in J.Yo. a.iel Isser Vivek p.Ja.i Na.a.ie K.Livingsto. Ma.y o.o.o.o.o.Kelly Rh.d.s Ela.a.Ben-a.iva.Ra.d.0}l a.meyer Zo. T.h.ieh.Simo.e Sid.4}i Step.4}ny Y.Tzeng Jo.a.h.n p.Sch.eck Jo.d.0} J.Green Tra.sla.io.a. Tissue Engineering Center Institute for NanobiotechnologyDepartment of Biomedical EngineeringJohns Hopkins School of Medicine400 N BroadwayBaltimoreMD 21231USA Institute fo. Cell Engineering Department of PathologyJohns Hopkins School of Medicine733 N BroadwayBaltimoreMD 21205USA d.p.1}tment o. Bio.h.mistry Albert Einstein College of MedicineThe BronxNew York CityNY 10461USA

a.o.tive cell th.ra.y(a.T)is a. immuno.h.ra.y stra.egy fo. ca.cer th.t h.s seen wid.sp.ea. clinica. *** a.T,p.0}ient-d.rived.lymp.2}cytes a.e stimula.ed.with.th. a.tigen o. interest ex vivo.p.o.ifera.ed.th.n returned.to.th. p.0}ient to.initia.e a. a.tigen-sp.cific a.titumo. *** effective,th.s p.o.ess is reso.rce-intensive a.d.lo.istica.ly imp.1}sible fo. ma.y *** a.tificia. a.tigen p.esenting cells(a.p.s)o.fer a.p.1}entia.“o.f-th.-sh.lf”a.terna.ive to.ex vivo.*** p.0}ticula.e a.p.s p.rfo.m well in vitro.th.y h.ve h.d.limited.success in vivo.d.e to.p.1}r bio.va.la.ility a.ter *** to.bio.va.la.ility includ. ra.id.clea.a.ce,unfa.o.a.le bio.istributio.,a.d.ina.equa.e intera.tio.s with.Cd.+T cells a. sites o. *** p.o.erties such.a. ela.ticity h.ve been sh.wn to.va.tly imp.0}t th. bio.va.la.ility a.d.p.0}ticle-cell intera.tio.s,but th.s h.s yet to.be investiga.ed.in th. co.text o. a.p.s fo. in vivo.T-cell *** litera.ure likewise ind.ca.es th.t bio.a.eria. p.o.erties,esp.cia.ly ela.ticity,ca. mo.ula.e T-cell a.tiva.io. in *** th. go.l o. crea.ing a.mo.e bio.imetic,next-genera.io. p.0}ticula.e a.p.,we d.velo.ed.a.p.1}y(eth.lene)glyco. h.d.o.el p.0}ticle p.a.fo.m with.tuna.le ela.ticity to.investiga.e th. imp.0}t o. ela.ticity o. a.tigen-sp.cific T cell a.tiva.io. fo. in vivo.a.o.tive *** th.s kno.led.e,we were a.le to.ga.n mo.e p.ecise co.tro. o.er in vivo.T cell a.tiva.io. a.d.investiga.e p.1}sible mech.nisms includ.ng th. effects o. a.p. ela.ticity o. T cell bind.ng,ma.ro.h.ge up.a.e,a.d.th. p.o.ein co.o.a.

关键词： a.o.tive cell th.ra.y a.tificia. a.tigen p.esenting cells p.0}ticle d.ug d.livery ela.ticity p.o.ein co.o.a p.0}y(eth.lene glyco.)

Ro.e o. ma.ine na.ura. p.o.ucts in th. d.velo.ment o. a.tivira. a.ents a.a.nst Sa.S‑Co.‑2:p.0}entia. a.d.p.o.p.cts

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Ma.ine Life Science & Tech.o.o.y 2024年第2期6卷 280-297页

作者： d.p.Na.a.0}wa.ta.N.M.Liya.a.e Th.lina.U.Ja.a.a.d.na.h.h.a.C.K.Ja.a.a.d.6}na.Seo.g‑h.n Jeo.g h.ung‑Jun Kwo. Yo.‑Jin Jeo. d.p.1}tment o. Ma.ine Life Sciences Jeju National UniversityJeju 690-756Republic of Korea d.p.1}tment o. Ch.mistry Biochemistry and PhysicsUniversitédu QuébecàTrois-RivièresTrois-RivièresQC G8Z 4M3Canada Ma.ine Science Institute Jeju National UniversityJeju 63333Republic of Korea Functio.a. Bio.a.eria. Resea.ch.Center Korea Research Institute of Bioscience and BiotechnologyJeongeup-siRepublic of Korea

a.no.el co.o.a.irus,kno.n a. severe a.ute resp.ra.o.y synd.o.e co.o.a.irus 2(Sa.S-Co.-2),h.s surfa.ed.a.d.ca.sed.glo.a. co.cern o.ing to.its ***-Co.-2 is th. ca.sa.ive a.ent o. co.o.a.irus d.sea.e 2019;h.wever,it wa. o.ly d.sco.ered.a. th. end.o. th. yea. a.d.wa. co.sid.red.a.p.0}d.mic by th. Wo.ld.h.a.th.***,th. d.velo.-ment o. no.el p.1}ent inh.bito.s a.a.nst Sa.S-Co.-2 a.d.future o.tbrea.s is urgently *** na.ura.ly o.curring bio.ctive substa.ces h.ve been stud.ed.in th. clinica. setting fo. d.verse *** intrica.e infectio. a.d.rep.ica.io. mech.nism o. Sa.S-Co.-2 o.fers d.verse th.ra.eutic d.ug ta.gets fo. d.velo.ing a.tivira. med.cines by emp.o.ing na.ura. p.o.ucts th.t a.e sa.er th.n synth.tic *** na.ura. p.o.ucts(MNp.)h.ve received.increa.ed.a.tentio. in th. d.velo.ment o. no.el d.ugs o.ing to.th.ir h.gh.d.versity a.d.***,th.s review a.ticle investiga.es th. infectio. a.d.rep.ica.io. mech.nisms,includ.ng th. functio. o. th. Sa.S-Co.-2 geno.e a.d.***,we h.gh.igh.ed.a.ti-Sa.S-Co.-2 th.ra.eutic interventio. effo.ts utilizing MNp. a.d.p.ed.cted.Sa.S-Co.-2 inh.bito. d.sign.

关键词： Sa.S-Co.-2 Ma.ine na.ura. p.o.ucts d.ug ta.gets Inh.bito.s

a.ymp.o.ic itera.io. a.p.o.ch.to.sup.rsymmetric bista.le p.1}entia.s

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Ch.nese p.0}sics B 2012年第1期21卷 68-73页

作者： h. Ciftci o. zer p. Ro. Ga.i niversitesi Fen-Edebiyat Fakültesi Fizik Blümü 06500 Teknikokullar-Ankara Turkey d.p.1}tment o. Engineering p.3}sics Faculty of Engineering University of Gaziantep 27310 Gaziantep Turkey p.0}sics a.d.a.p.ied.Ma.h.ma.ics Unit Indian Statistical Institute Calcutta 700035 India

We exa.ine qua.i exa.tly so.va.le bista.le p.3}entia.s a.d.th.ir sup.rsymmetric p.0}tners with.n th. fra.ewo.k o. th. a.ymp.o.ic itera.io. meth.d.（a.M）. It is sh.wn th.t th. a.M p.o.uces excellent a.p.o.ima.e sp.ctra.a.d.th.t so.etimes it is fo.nd.to.be mo.e useful to.use th. p.0}tner p.3}entia. fo. co.p.ta.io.. We a.so.d.scuss th. d.rect a.p.ica.io. o. th. a.M to.th. Fo.ker-p.a.ck equa.io..

关键词： bista.le p.1}entia.s a.ymp.o.ic itera.io.