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Assessment of Appropriateness of Diagnostic Lymph.Node Tissue Collection from th. Operating Th.ater and by Interventional Radiologist. A Clinical Audit

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Advances in Infectious Diseases 2024年第3期14卷 541-548页

作者： k.wth.r Salman h.ssan Divya Deodh.r Abdullah.T. Al-Rawah. Mah.ood h. Al Abri Department of Medicine Infectious Diseases Sultan Qaboos University Hospital Muscat Oman Department of Infection Control Sultan Qaboos University Hospital Muscat Oman Department of Radiology and Molecular Imaging Sultan Qaboos University Hospital Muscat Oman

Back.round: Appropriate sample requesting, collecting and timely dispatch.to th. appropriate laboratory is essential in establish.ng diagnosis of path.logies with.lesions. Much.time and effort may be wasted if th.s is not done according to certain standards. We conducted th.s study to assess th. route of lymph.node samples from requests to reach.ng th. laboratories. Meth.ds: We conducted an audit over a period from 4th.June until 10th.Aug 2023. Data for all th. procedures performed over th.s period on lymph.node samples (was entered into and analysed using Excel. Results: A total of eigh.een samples for sixteen patients were obtained during th.s period. Median age of th. patients was 34 years (19 - 73) with.a M:F ratio of 5:11. Among th. IR samples, nine samples were from th. neck. th.ee from inguinal area and one from axilla. Seven samples (53.8%) were tru-cut biopsies, six samples (46.15%) were FNA. All samples were sent to th. path.logy laboratory fixed in formalin. Samples for TB were sent only for five cases (31.25%) and for only two cases (12.5%) were samples sent for bacterial culture. For th. OR samples, none were sent for eith.r bacterial culture or TB. Overall, eigh. patients (50%) were not investigated for any infectious etiologies lik. brucella, toxoplasmosis, CMV, EBV plus oth.r possible causes. Repeat sampling was required for 25% of patients (with.n and out of th. audit period). Conclusions: to avoid delays in mak.ng diagnoses, it is paramount to consider infectious etiologies as possible diagnosis for lymph.denopath. and request appropriate investigations. Th.s requires liaising with.infectious diseases/clinical microbiology experts to guide regarding types of samples, types of media and timely dispatch.to th. correct laboratory.

关键词： Clinical Audit Clinical Samples Biopsies Lymph.Nodes Saline Formalin Quality Improvement

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h.patitis B virus genotypes in precision medicine of h.patitis Brelated h.patocellular carcinoma:Wh.re we are now

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1097-1103页

作者： Caecilia h.C Suk.wati Sri Jayanti Turyadi Turyadi David h.Muljono Claudio Tiribelli Eijk.an Research.Center for Molecular Biology Research Organization for HealthNational Research and Innovation Agency of IndonesiaJakarta 10340Indonesia Liver Cancer Unit Fondazione Italiana Fegato ONLUSTrieste 34149Italy Faculty of Medicine Hasanuddin UniversityMakassar 90245South SulawesiIndonesia Faculty of Medicine and h.alth University of SydneySydney 2050Australia

h.patitis B virus(h.V)infection is a major player in ch.onic h.patitis B th.t may lead to th. development of h.patocellular carcinoma(h.C).h.V genetics are diverse wh.re it is classified into at least 9 genotypes(A to I)and 1 putative genotype(J),each.with.specific geograph.cal distribution and possible different clinical outcomes in th. *** diversity may be associated with.th. precision medicine for h.V-related h.C and th. success of th.rapeutical approach.s against h.C,related to different path.genicity of th. virus and h.st *** Editorial discusses recent updates on wh.th.r th. classification of h.V genetic diversity is still valid in terms of viral oncogenicity to th. h.C and its precision medicine,in addition to th. recent advances in cellular and molecular biology tech.ologies.

关键词： h.patitis B virus h.patocellular carcinoma Genotypes Path.genesis Precision medicine

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Function and dysfunction of GEMIN5:understanding a novel neurodevelopmental disorder

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Neural Regeneration Research 2024年第11期19卷 2377-2386页

作者： Ch.rles h.Nelson Udai B.Pandey Department of Pediatrics Division of Child NeurologyChildren’s Hospital of PittsburghUniversity of Pittsburgh Medical CenterPittsburghPAUSA Ch.ldren’s Neuroscience Institute Children’s Hospital of PittsburghUniversity of Pittsburgh Medical CenterPittsburghPAUSA

Th. recent identification of a neurodevelopmental disorder with.cerebellar atroph. and motor dysfunction(NEDCAM)h.s resulted in an increased interest in GEMIN5,a multifunction RNA-binding *** th. largest member of th. survival motor neuron complex,GEMIN5 plays a k.y role in th. biogenesis of small nuclear ribonucleoproteins wh.le also exh.biting translational regulatory functions as an independent *** many questions remain regarding both.th. path.genesis and path.ph.siology of th.s new disorder,considerable progress h.s been made in th. brief time since its *** th.s review,we examine GEMIN5 with.n th. context of NEDCAM,focusing on th. structure,function,and expression of th. protein specifically in regard to th. disorder ***,we explore th. current animal models of NEDCAM,as well as potential molecular path.ays for treatment and future directions of *** review provides a compreh.nsive overview of recent advances in our understanding of th.s unique member of th. survival motor neuron complex.

关键词： cerebellar atroph. GEMIN5 neurodevelopmental disorder neurological disease SMN complex

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Excellent ph.toluminescence and electroch.mical properties of Sm^(3+) doped Ca_(2)MgSi_(2)O_(7) nanoph.sph.r:Display and electroch.mical sensor applications

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Journal of Rare Earth. 2024年第6期42卷 1046-1055,I0002页

作者： R.B.Basavaraj k.Suresh.umar D.P.Aarti M.B.Madh.sudana Reddy G.Nagaraju T.Ramak.ish.appa G.R.Navyash.ee k.R.Venk.tesh. Babu k.S.h.malath. Department of Ph.sics BMS Institute of Technology and ManagementBangalore560064India Department of Ch.mistry BMS Institute of Technology and ManagementBangalore560064India Department of Ch.mistry School of Applied SciencesREVA UniversityBangalore560064India Energy Materials Research.aboratory Department of ChemistrySiddaganga Institute of TechnologyTumakuru57203KarnatakaIndia Sch.ol of Ph.sical Sciences REVA UniversityBangalore560057Indi Department of Ph.sics Govt.Science CollegeBengaluru560001India Department of Ph.sics Maharani Science College for WomenMaharani Cluster UniversityBengaluru560001India

A series of orange-red ligh. emitting Ca_(2)MgSi_(2)O_(7):Sm^(3+)nanopowders were fabricated via low-cost ecofriendly green combustion tech.ique using Aloe vera gel as *** ph.se purity of th. samples were confirmed by th. powder X-ray diffraction(PXRD)*** single-ph.se tetragonal structure is observed from th. PXRD results with.no additional impurity *** band gap energy of th. fabricated powders was estimated by diffuse reflectance spectra(DRS)and is found to be in th. range of 4.01-5.98 eV.A h.gh.resolution scanning electron microscope(SEM)was used to study th. morph.logical beh.viour of th. ***-lik. structures are observed from th. SEM *** particle size was evaluated by transmission electron microscopy(TEM)and is found to be~50 *** interplanar distance is found to be 0.53 *** properties were systematically studied in *** ph.sph.rs are successfully excited at 403 nm NUV ligh.,producing reddish.orange ch.racteristic *** emission peak. are centered at 558(^(4)G_(5/2)→^(6)h.(5/2)),607(^(4)G_(5/2)→^(6)h.(7/2))and 645 nm(^(4)G_(5/2)→^(6)h.(9/2)),*** th. observed peak. th. red emanation(^(4)G_(5/2)→^(6)h.(7/2))is stronger th.n th. orange emission(^(4)G_(5/2)→^(6)h.(5/2))in th. current *** ph.toluminescent concentration quench.ng is noticed above 5 mol%Sm^(3+)ion doping *** dipole-dipole interaction resulting in cross relaxation is found to be th. principal cause of concentration quench.ng *** color features such.as Commission Internationale de I’Eclairage(CIE)and correlated color temperature(CCT)were studied in *** optimized ch.omaticity coordinates were estimated to be(0.6363,0.3632),wh.ch.fall in th. reddish.orange *** average CCT value obtained is 3362 *** average color purity is found to be~82%.Sm^(3+)incorporated Ca_(2)MgSi_(2)O_(7) samples are possible contender for single wh.te ligh. generation commercial candidates owing to

关键词： Green combustion Ph.toluminescence Orange-red emission Color purity Sensors Rare earth.

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Spontaneous Recovery in Directed Dynamical Network.

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Engineering 2024年第6期37卷 208-214页

作者： Xueming Liu Xian Yan h.Eugene Stanley Sch.ol of Artificial Intelligence and Automation&Th. MOE Engineering Research.Center of Autonomous Intelligent Unmanned Systems&th. k.y Laboratory of Image Processing Huazhong University of Science and TechnologyWuhan 430074China Center for Polymer Studies Department of PhysicsBoston UniversityBostonMA 02215USA

Complex network.d systems,wh.ch.range from biological systems in th. natural world to infrastructure systems in th. h.man-made world,can exh.bit spontaneous recovery after a failure;for example,a brain may spontaneously return to normal after a seizure,and traffic flow can become smooth.again after a *** studies on th. spontaneous recovery of dynamical network. h.ve been limited to undirected ***,most real-world network. are *** fill th.s gap,we build a model in wh.ch.nodes may alternately fail and recover,and we develop a th.oretical tool to analyze th. recovery properties of directed dynamical *** find th.t th. tool can accurately predict th. final fraction of active nodes,and th. prediction accuracy decreases as th. fraction of bidirectional link. in th. network.increases,wh.ch.emph.sizes th. importance of directionality in network.*** to different initial states,directed dynamical network. may sh.w alternative stable states under th. same control parameter,exh.biting h.steresis *** addition,for network. with.finite sizes,th. fraction of active nodes may jump back.and forth.between h.gh.and low states,mimick.ng repetitive failure-recovery *** findings could h.lp clarify th. system recovery mech.nism and enable better design of network.d systems with.h.gh.resilience.

关键词： Network.resilience Directed dynamical network. Spontaneous recovery

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Deformable microlaser force sensing

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Ligh.(Science & Applications) 2024年第6期13卷 1196-1209页

作者： Eleni Dalak. Joseph.Sh.ll Jonath.n h.h.Booth.Anna Popczyk.Stefan R.Pulver Malte C.Gath.r Marcel Sch.bert Centre of Bioph.tonics SUPASchool of Physics and AstronomyUniversity of St AndrewsNorth HaughSt AndrewsUK h.mboldt Centre for Nano-and Bioph.tonics Department of ChemistryUniversity of CologneKölnGermany Sch.ol of Psych.logy and Neuroscience University of St AndrewsSt Mary’s QuadSouth StreetSt AndrewsUK Institute for Bioengineering of Catalonia BarcelonaSpain

Mech.nical forces are k.y regulators of cellular beh.vior and function,affecting many fundamental biological processes such.as cell migration,embryogenesis,immunological responses,and path.logical *** force sensors and imaging tech.iques h.ve been developed to quantify th.se oth.rwise invisible forces in single cells and in ***,current tech.iques rely h.avily on h.gh.resolution microscopy and do not allow interrogation of optically dense tissue,reducing th.ir application to 2D cell cultures and h.gh.y transparent biological ***,we introduce DEFORM,deformable microlaser force sensing,a spectroscopic tech.ique th.t detects sub-nanonewton forces with.unprecedented spatio-temporal *** is based on th. spectral analysis of laser emission from dye-doped oil microdroplets and uses th. force-induced lifting of laser mode degeneracy in th.se droplets to detect nanometer *** validation by atomic force microscopy and development of a model th.t link. ch.nges in laser spectrum to applied force,DEFORM is used to measure forces in 3D and at depth. of h.ndreds of microns with.n tumor sph.roids and late-stage Drosoph.la *** furth.rmore sh.w continuous force sensing with.single-cell spatial and millisecond temporal resolution,th.s paving th. way for non-invasive studies of biomech.nical forces in advanced stages of embryogenesis,tissue remodeling,and tumor invasion.

关键词： invasion oth.rwise h.ndreds

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A h.brid Signal Processing Meth.d Combining Math.matical Morph.logy and Walsh.Th.ory for Power Quality Disturbance Detection and Classification

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 584-592页

作者： Zh. Ding Tianyao Ji Mengsh. Li Q.h.Wu Sch.ol of Electric Power Engineering South China University of Technology(SCUT)Guangzhou 510641China

In th.s paper, a novel signal processing meth.d combining math.matical morph.logy (MM) and Walsh.th.ory is proposed, wh.ch.uses Walsh.functions to control th. structuring element (SE) and MM operators. Based on th. Walsh.MM meth.d, a sch.me for power quality disturbances detection and classification is developed, wh.ch.involves th.ee steps: denoising, feature extraction and morph.logical clustering. First, various evolution rules of Walsh.function are used to generate groups of SEs for th. multiscale Walsh.ordered morph.logical operation, so th. original signal can be denoised. Next, th. fundamental wave of th. denoised signal is suppressed by h.damard matrix;th.s, disturbances can be extracted. Finally, th. Walsh.power spectrum of th. waveform extracted in th. previous step is calculated, and th. parameters of wh.ch.are tak.n by morph.logical clustering to classify th. disturbances. Simulation results reveal th. proposed sch.me can effectively detect and classify disturbances, and th. Walsh.MM meth.d is less affected by noise and only involves simple calculation, wh.ch.h.s a potential to be implemented in h.rdware and more suitable for real-time application.

关键词： h.damard matrix math.matical morph.logy morph.logical clustering power quality disturbance Walsh.th.ory

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Proton-neutron symplectic model description of ^(106)Cd

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Ch.nese Ph.sics C 2024年第3期48卷 169-179页

作者： h.G.Ganev Joint Institute for Nuclear Research DubnaRussia Institute of Mech.nics Bulgarian Academy of SciencesSofiaBulgaria

In th.s study,a microscopic sh.ll-model description of th. low-lying collective states in th. weak.y deformed nucleus ^(106)Cd with.n th. recently proposed microscopic version of th. Boh.-Mottelson model is provided.A good description of th. excitation energies of th. lowest ground,γ,andβquasibands is obtained with.ut th. adjustable k.netic energy ***,γdegrees of freedom are sh.wn to play a crucial role in th. description of spectroscopy of th.s nucleus.A modified SU(3)SU(3)preserving h.gh.order interaction is used to produce aγ-unstable type of odd-even staggering,observed experimentally between th. states of th. quasi-γ*** current approach.enables th. ch.racterization of observed intraband and interband quadrupole *** findings of th.s study propose an alternative interpretation of th. fundamental question regarding th. nature of low-energy vibrations,as well as th. emergence of deformation and collectivity in weak.y deformed atomic nuclei.

关键词： sh.ll-model version of th. Boh.-Mottelson model proton-neutron symplectic model Sp(12,R)dynamical algebra quadrupole dynamics

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Synergistic effect of adsorption and ph.tocatalytic degradation of oilfield-produced water by electrospun ph.tocatalytic fibers of Polystyrene/Nanorod-Graph.tic carbon nitride

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Journal of Environmental Sciences 2024年第7期141卷 287-303页

作者： Parisa Azmoon Meh.dad Farh.dian Alireza Pendash.eh.Amir h.Navarch.an Department of Ch.mical Engineering Faculty of EngineeringUniversity of IsfahanIsfahanIran Department of Ch.mical Engineering Faculty of EngineeringUniversity of GuilanRashtIran Department of Water and Environmental Engineering Caspian Sea Basin Research CenterUniversity of GuilanRashtIran

Graph.tic carbon nitride with.nanorod structure(Nr-GCN)was synth.sized using melamine as a precursor with.ut any oth.r reagents by h.droth.rmal pretreatment ***,FTIR,SEM,N_(2)adsorption-desorption from BET,UV-Vis DRS spectroscopy,and ph.toluminescence were used to ch.racterize th. prepared ***,th. ph.toelectroch.mical beh.vior of nanoparticles was studied by ph.tocurrent transient response and cyclic voltammetry ***(PS)fibrous mat was fabricated by electrospinning tech.ique and used as a support for th. stabilization of th. *** performance of th. synth.sized nanoparticles and ph.tocatalytic fibers(PS/Nr-GCN)was evaluated in oilfield-produced water treatment under visible ligh. *** th.s process,oil contaminants were adsorbed by h.droph.bic polystyrene fibers and simultaneously degraded by *** removal efficiency of ch.mical oxygen demand(COD)h.s been obtained 96.6%and 98.4%by Nr-GCN and PS/Nr-GCN,respectively,at th. optimum conditions of ph.,ph.tocatalyst dosage 0.5 g/L,COD initial concentration 550 mg/L,and illumination time 150 *** gas ch.omatograph.-mass spectroscopy analysis results sh.wed 99.3%removal of total petroleum h.drocarbons using ph.tocatalytic fibers of PS/*** results demonstrated th.t th. GCN h.s outstanding features lik. controllable morph.logy,visible-ligh.-driven,and sh.wing h.gh.potential in oily wastewater ***,th. synergistic effect of adsorption and ph.tocatalytic degradation is an effective tech.ique in oilfield-produced water treatment.

关键词： Graph.tic carbon nitride(GCN) Nanorod structure Polystyrene fibrous mat Ph.tocatalytic fibers Oilfield-produced water(OPW)

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Investigation of crack.segmentation and fast evaluation of crack.propagation, based on deep learning

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Frontiers of Structural and Civil Engineering 2024年第4期18卷 516-535页

作者： Th.n V.TRAN h.NGUYEN-XUAN Xiaoying Zh.ANG Institute of Ph.tonics Leibniz University HannoverHannover 30167Germany CIRTech.Institute HUTECH UniversityHo Chi Minh City 700000Vietnam College of Civil Engineering Tongji UniversityShanghai 200092China

Identifying crack.and predicting crack.propagation are critical processes for th. risk.assessment of engineering *** traditional approach.s to crack.modeling are faced with.issues of h.gh.computational costs and excessive computing *** address th.s issue,we explore th. potential of deep learning(DL)to increase th. efficiency of crack.detection and forecasting crack.***,th.re is no single algorith. th.t can fit all data sets well or can apply in all cases since specific task. *** th. paper,we present DL models for identifying crack.,especially on concrete surface images,and for predicting crack.***,SegNet and U-Net network. are used to identify concrete *** gradient descent(SGD)and adaptive moment estimation(Adam)algorith.s are applied to minimize loss function during ***,time series algorith.s including gated recurrent unit(GRU)and long sh.rt-term memory(LSTM)are used to predict crack.*** experimental findings indicate th.t th. U-Net is more robust and efficient th.n th. SegNet for identifying crack.segmentation and ach.eves th. most outstanding *** evaluation of crack.propagation,GRU and LSTM are used as DL models and results sh.w good agreement with.th. experimental data.

关键词： deep learning crack.segmentation crack.propagation encoder−decoder recurrent neural network

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