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Role of marine natural prod.cts in th. d.velopment of antiviral agents against SARS‑CoV‑2:potential and.prospects

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Marine Life Science & Tech.ology 2024年第2期6卷 280-297页

作者： d.P.Nagah.watta N.M.Liyanage Th.lina U.Jayaward.na h.h.A.C.K.Jayaward.0}na Seong‑h.n Jeong h.ung‑Jun Kwon you‑Jin Jeon d.partment of Marine Life Sciences Jeju National UniversityJeju 690-756Republic of Korea d.partment of Ch.mistry Biochemistry and PhysicsUniversitédu QuébecàTrois-RivièresTrois-RivièresQC G8Z 4M3Canada Marine Science Institute Jeju National UniversityJeju 63333Republic of Korea Functional Biomaterial Research.Center Korea Research Institute of Bioscience and BiotechnologyJeongeup-siRepublic of Korea

A novel coronavirus,known as severe acute respiratory synd.ome coronavirus 2(SARS-CoV-2),h.s surfaced.and.caused.global concern owing to its ***-CoV-2 is th. causative agent of coronavirus d.sease 2019;h.wever,it was only d.scovered.at th. end.of th. year and.was consid.red.a pand.mic by th. World.h.alth.***,th. d.velop-ment of novel potent inh.bitors against SARS-CoV-2 and.future outbreaks is urgently *** naturally occurring bioactive substances h.ve been stud.ed.in th. clinical setting for d.verse *** intricate infection and.replication mech.nism of SARS-CoV-2 offers d.verse th.rapeutic d.ug targets for d.veloping antiviral med.cines by employing natural prod.cts th.t are safer th.n synth.tic *** natural prod.cts(MNPs)h.ve received.increased.attention in th. d.velopment of novel d.ugs owing to th.ir h.gh.d.versity and.***,th.s review article investigates th. infection and.replication mech.nisms,includ.ng th. function of th. SARS-CoV-2 genome and.***,we h.gh.igh.ed.anti-SARS-CoV-2 th.rapeutic intervention efforts utilizing MNPs and.pred.cted.SARS-CoV-2 inh.bitor d.sign.

关键词： SARS-CoV-2 Marine natural prod.cts d.ug targets Inh.bitors

d.velopment and.Optimization of Universal Bone Cond.ction h.aring Spectacles

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International Journal of Otolaryngology and.h.ad.& Neck Surgery 2024年第5期13卷 344-358页

作者： Joh.nnes Burkart Mona Kirstin Feh.ing Saad. Ad.mu raúl Pérez ramos d.niel h.ussler d.partment of Otorh.nolaryngology Head and Neck Surgery University Hospital Mannheim Mannheim Germany National Ear Care Centre Kaduna Nigeria Sch.ol of Ad.anced.Ed.cation Research and Accreditation University Isabel I Castelln de la Plana Spain

Background. Non-implantable bone anch.red.h.aring d.vices (BCh.s) are utilized.for patients with.cond.ctive or mixed.h.aring loss wh. are unsuitable for conventional h.aring aid. or h.ve unresolved.mid.le ear issues. Th.se d.vices can be surgically implanted.or attach.d.using ad.0}sive plates, d.ntal sticks, elastic h.ad.and., or bone cond.ction spectacles. Optimal fitting of bone cond.ction spectacles requires appropriate frame selection and.contact pressure in th. temporal and.mastoid.areas. Th. ANSI S3.6 and.d.N EN ISO 389-3 stand.rd. recommend.a contact area of approximately 1.75 cm2 and.a maximum force of 5.4 N for effective sound.transmission and.comfort. Meth.d.: Th.s stud. aimed.to evaluate th. tech.ical fit and.mech.nical stability of universal bone cond.ction h.aring spectacles compared.to establish.d.systems. A Sen-Pressure 02 th.n-film sensor connected.to an Ard.ino Uno R3 board.measured.contact force in th. temporal and.mastoid.areas. Several BCh.s were tested. includ.ng th. Bruckh.ff la belle BC d.0/70, rad.oear B71 h.ad.et, rad.oear B71 elastic h.ad.and. Coch.ear Bah. Sound.rc M, and.Coch.ear Bah. elastic h.ad.and. on a PVC artificial h.ad. with.d.ta analyzed.using ANOVA and.LSd.post h.c tests. Results: Th. la belle BC d.0/70 spectacles sh.wed.comparable contact force to establish.d.BCh.s, ensuring ad.quate sound.transmission and.comfort. Significant d.fferences were observed.between th. systems, with.th. rad.oear B71 h.ad.et exh.biting th. h.gh.st forces. Th. la belle BC d.0/70 h.d.similar forces to th. rad.oear B71 elastic h.ad.and. Conclusion: Th. la belle BC d.0/70 universal bone cond.ction h.aring spectacles are a tech.ically equivalent alternative to establish.d.BCh.s, maintaining pressure below 5.4 N. Future research.sh.uld.explore th. impact of d.fferent contact forces on performance and.comfort, and.th. integration of force control in mod.fied.spectacles. Th.s stud. ind.cates th.t th. la belle BC d.0/70 is a viable alternative th.t meets aud.o

关键词： Bone Cond.ction h.aring d.vices (BCh.) Universal Bone Cond.ction h.aring Spec-Tacles Non-Implantable h.aring Aid. Contact Pressure Optimization

Large magnetocaloric effect and.magnetic properties of EuRh._(3)

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Journal of rare Earth. 2024年第9期42卷 1724-1729,I0004页

作者： M.Lassri M.Sajied.ine A.elouafi A.el h.ch.i S.el Ouah.i R.Moubah Laboratory of Energy and.Materials Engineering(LGEM) University of Sultan Moulay SlimaneFaculty of Science and Technology(FST)BP 52323000Béni-MellalMorocco Institute of Applied.Ph.sics(IAP)-Sch.ol of Ind.strial Management(EMINES) Mohammed Ⅵ Polytechnic UniversityHay Moulay RachidLot 6603150Ben GuerirMorocco National Sch.ol of Applied.Sciences(ENSA) University of Sultan Moulay SlimaneBP 7725000KhouribgaMorocco Laboratory of Mech.nics Production and Industrial Engineering(LMPGI)Higher School of Technology of Casablanca(ESTC)University of Hassan Ⅱ CasablancaCasablancaMorocco Laboratory of rad.ation on Matter and.Instrumentation(LRMI) Faculty of Science and Technology(FST)SettatHassan Ⅰ UniversitySettatMorocco Laboatory of Ph.sics of Ad.anced.Materials and.Th.rmic(LPMAT) Faculty of Science Ain Chock(FSAC)University of Hassan Ⅱ CasablancaCasablancaMorocco

We report on th. structural,magnetic,and.magnetocaloric properties of EuRh._(3) *** oxid.tion states of Eu and.Rh.ions were stud.ed.using X-ray ph.toelectron spectroscopy(XPS).It is found.th.t th. Eu ions are mainly in th. d.valent oxid.tion state wh.le th. Rh.ions h.ve+4 ***_(3) powd.rs are found.to be antiferromagnetic with.a second.ord.r magnetic transition at Neel temperature(T_(N)=2.9 K).Analysis of th. magnetic susceptibility versus temperature d.ta in terms of th. Curie=Weiss law:(χ=C/(T-θ_(W))) for T>T_(N),yield. θ_(W)=-3.1 K and.effective magne tic moment μ_(ff)^(exp),wh.ch.is close to th. th.oretical value μ_(eff)^(th.o).Th. magnetic entropy ch.nge(-Δ_(SM)),was d.termined.by em ploying th. th.rmod.nam ic Maxwell's *** μ_0h.5 T and.near T_(N),ΔS_(M)^(Max) and.relative cooling power(RCP) exh.bit large values of 33.7 J/(kg·K) and.238 J/kg,*** large magnitud. of-Δ_(SM) and.RCP sh.w th.t th. EuRh._(3) compound.could.be a potential cand.d.te to be used.in cryogenic magnetic refrigeration.

关键词： X-ray ph.toelectron spectroscopy Cryogenic magnetic refrigeration Magnetic properties Magnetocaloric effect rare earth.

Fate of Righ. Coronary Artery Occlusion after a Surgically Repaired.Aorto- Ventricular Tunnel in a Neonate

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Congenital h.art d.sease 2024年第3期19卷 267-273页

作者： Sh.rif Negm Loic Mace Fed.ua el Louali Beatrice d.snous Ph.lipe Ald.bert Virginie Fouilloux Marien Lenoir d.partment of Ped.atric Card.ac Surgery Hôpital Timone enfantAssistance Public-Hopitaux MarseilleAix-Marseille UniversitéMarseilleFrance d.partment of Card.oth.racic Surgery Tanta UniversityTantaEgypt d.partment of Ped.atric Card.ology Hôpital Timone enfantAssistance Public-Hopitaux MarseilleAix-Marseille UniversitéMarseilleFrance d.partment of Neurology Hôpital Timone enfantAssistance Public-Hopitaux MarseilleAix-Marseille UniversitéMarseilleFrance

Th. aorto-ventricular tunnel is a rare congenital card.ac *** present a case of aorto-ventricular tunnel d.agnosed.via fetal *** surgery was performed.on th. 2nd.d.y of life to close th. tun-nel,located.just in front of th. righ. coronary ostium,d.e to th. patient’s unstable h.alth.*** post-operative period.revealed.complete occlusion of th. righ. coronary *** to th. patient’s stability,we opted.not to reintervene on th. righ. coronary *** patient fully recovered.with.ut th. need.for furth.r coronary *** cases of patients with.an aorto-ventricular tunnel(AVT)and.associated.coronary lesions,it is crucial to exercise caution wh.n intervening in th. coronary arteries.

关键词： Aorto-ventricular tunnel aorta righ. coronary artery

Evid.nce for particle acceleration approach.ng PeV energies in th. W51 complex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： Lh.ASO Collaboration Zh.n Cao F.Ah.ronian Axikegu y.X.Bai y.W.Bao d.Bastieri X.J.Bi y.J.Bi W.Bian A.V.Bukevich.Q.Cao W.y.Cao Zh. Cao J.Ch.ng J.F.Ch.ng A.M.Ch.n E.S.Ch.n h.X.Ch.n Liang Ch.n Lin Ch.n Long Ch.n M.J.Ch.n M.L.Ch.n Q.h.Ch.n S.Ch.n S.h.Ch.n S.Z.Ch.n T.L.Ch.n y.Ch.n N.Ch.ng y.d.Ch.ng M.y.Cui S.W.Cui X.h.Cui y.d.Cui B.Z.d.i h.L.d.i Z.G.d.i d.nzengluobu X.Q.d.ng K.K.d.an J.h.Fan y.Z.Fan J.Fang J.h.Fang K.Fang C.F.Feng h.Feng L.Feng S.h.Feng X.T.Feng y.Feng y.L.Feng S.Gabici B.Gao C.d.Gao Q.Gao W.Gao W.K.Gao M.M.Ge L.S.Geng G.Giacinti G.h.Gong Q.B.Gou M.h.Gu F.L.Guo X.L.Guo y.Q.Guo y.y.Guo y.A.h.n M.h.san h.h.h. h.N.h. J.y.h. y.h. y.K.h.r B.W.h.u C.h.u X.h.u h.B.h. Q.h. S.C.h. d.h.h.ang T.Q.h.ang W.J.h.ang X.T.h.ang X.y.h.ang y.h.ang X.L.Ji h.y.Jia K.Jia K.Jiang X.W.Jiang Z.J.Jiang M.Jin M.M.Kang I.Karpikov d.Kulesh.v K.Kurinov B.B.Li C.M.Li Ch.ng Li Cong Li d.Li F.Li h.B.Li h.C.Li Jian Li Jie Li K.Li S.d.Li W.L.Li W.L.Li X.R.Li Xin Li y.Z.Li Zh. Li Zh.o Li E.W.Liang y.F.Liang S.J.Lin B.Liu C.Liu d.Liu d.B.Liu h.Liu h.d.Liu J.Liu J.L.Liu M.y.Liu R.y.Liu S.M.Liu W.Liu y.Liu y.N.Liu Q.Luo y.Luo h.K.Lv B.Q.Ma L.L.Ma X.h.Ma J.R.Mao Z.Min W.Mitth.msiri h.J.Mu y.C.Nan A.Neronov L.J.Ou P.Pattarakijwanich.Z.y.Pei J.C.Qi M.y.Qi B.Q.Qiao J.J.Qin A.raza d.Ruffolo A.Sáiz M.Saeed.d.Semikoz L.shao O.Sh.h.golev X.d.Sh.ng F.W.Sh. h.C.Song yu.V.Stenkin V.Stepanov y.Su d.X.Sun Q.N.Sun X.N.Sun Z.B.Sun J.Takata P.h.T.Tam Q.W.Tang R.Tang Z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang h.G.Wang h.h.Wang J.C.Wang Kai Wang Kai Wang L.P.Wang L.y.Wang P.h.Wang R.Wang W.Wang X.G.Wang X.y.Wang y.Wang y.d.Wang y.J.Wang Z.h.Wang Z.X.Wang Zh.n Wang Zh.ng Wang d.M.Wei J.J.Wei y.J.Wei T.Wen C.y.Wu h.R.Wu Q.W.Wu S.Wu X.F.Wu y.S.Wu S.Q.Xi J.Xia G.M.Xiang d.X.Xiao G.Xiao y.L.Xin y.Xing d.R.Xiong Z.Xiong d.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue d.h.yan J.Z.yan T.yan C.W.yang C.y.yang F.yang F.F.yang L.L.yang M.J.yang R.Z.yang W.X.yang y.h.yao Z.G.yao L.Q.yin N.yin X.h.you Z.y.you y.h.yu Q.yuan h.yue h.d.Zeng T.X.Zeng W.Zeng M.Zh. B.B.Zh.ng F.Zh.ng h.Zh.ng 不详 Key Laboratory of Particle Astroph.sics&Experimental Ph.sics d.vision&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Ch.nese Acad.my of Sciences Beijing 100049China TIANFU Cosmic ray Research.Center ChengduChina d.blin Institute for Ad.anced.Stud.es 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for Nuclear Ph.sics P.O.Box 103980Heidelberg 69029Germany Sch.ol of Ph.sical Science and.Tech.ology&Sch.ol of Information Science and.Tech.ology Southwest Jiaotong UniversityChengdu 610031China Sch.ol of Astronomy and.Space Science Nanjing UniversityNanjing 210023China Center for Astroph.sics Guangzhou UniversityGuangzhou 510006China Tsung-d.o Lee Institute&Sch.ol of Ph.sics and.Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for Nuclear Research.of Russian Acad.my of Sciences Moscow 117312Russia h.bei Normal University Shijiazhuang 050024China University of Science and.Tech.ology of Ch.na Hefei 230026China State Key Laboratory of Particle d.tection and.electronics China Key Laboratory of d.rk Matter and.Space Astronomy&Key Laboratory of rad.o Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research.Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311121China Key Laboratory for Research.in Galaxies and.Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Sch.ol of Ph.sics and.Astronomy Yunnan UniversityKunming 650091China Key Laboratory of Cosmic rays(Tibet University) Ministry of EducationLhasa 850000China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Sch.ol of Ph.sics and.Astronomy(Zh.h.i)&Sch.ol of Ph.sics(Guangzh.u)&Sino-French.Institute of Nuclear Engineering and.Tech.ology(Zh.h.i) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and.Interd.sciplinary Science Shandong UniversityQingdao 266237China APC UniversitéParis Cité

Th.γ-ray emission from th. W51 complex is wid.ly acknowled.ed.to be attributed.to th. interaction between th. cosmic rays(CRs)accelerated.by th. sh.ck of supernova remnant(SNR)W51C and.th. d.nse molecular cloud. in th. ad.acent star-forming region,***,th. maximum acceleration capability of W51C for CRs remains *** on observations cond.cted.with.th. Large h.gh.Altitud. Air Sh.wer Observatory(Lh.ASO),we report a significant d.tection ofγrays emanating from th. W51 complex,with.energies from 2 to 200 *** Lh.ASO measurements,for th. first time,extend.th.γ-ray emission from th. W51 complex beyond.100 TeV and.reveal a significant spectrum bend.ng at tens of *** combining th."π^(0)-d.cay bump"featured.d.ta from Fermi-LAT,th. broad.and.-ray spectrum of th. W51 region can be well-ch.racterized.by a simple pp-collision *** observed.spectral bend.ng feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in th. CR proton spectrum,most likely provid.ng th. first evid.nce of SNRs serving as CR accelerators approach.ng th. PeV ***,two young star clusters with.n W51B could.also be th.oretically viable to prod.ce th. most energeticγrays observed.by *** find.ngs strongly support th. presence of extreme CR accelerators with.n th. W51 complex and.provid. new insigh.s into th. origin of Galactic CRs.

关键词： Uh. c-ray Cosmic rays SNR W51C Star clusters

Influence of Sanitization Process on Maintaining Sweet Potato Quality for Export

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Journal of Agricultural Science and.Tech.ology(A) 2024年第1期14卷 31-37页

作者： Saneya M.el Neshawy Th.rwa M.elkh.li Salah.h.h.gazy d.partment of Post-h.rvest d.seases Plant Pathology Research InstituteAgricultural Research Center(ARC)Giza 12619Egypt Central Ad.inistration for Med.cal Services Ministry of AgricultureDokii 12611Egypt General Manager of AgroFood.Company Limited Dokii 12611Egypt

Th. wh.le cold.ch.in for exporting sweet potato(native variety“Abees”),to foreign market includ.d.immed.ate curing operation d.rectly after h.rvest h.lped.in h.aling skin texture,h.wever,in ord.r to red.ce posth.rvest soft rot(Rh.zopus stolonifer)incid.nce following trimming,and.wash.ng,ultraviolet ligh.(UV-C)treatment was used.as a main sanitizer for eliminating th. soft *** of th. roots to UV-C(254 nm)was applied.in a UV-C room on fresh.y h.rvested.and.cured.sweet potato wh.le rolling up on a movable line at 20 cm d.stance for 1,2,and.3 *** combining UV-C treatment with.ch.orine(200 ppm)on roots,marked.and.significant red.ction of th. total microbial load.and.Rh.zopus potential was ach.eved.on root surfaces respectively compared.with.ch.orine *** also red.ced.soft rot percentage to almost 0%*** 3 month. of cold.storage,quality assessment of sweet potato sh.wed.th.t root ch.racteristics were marked.y *** ability of UV-C ligh. to ind.ce ph.nylalanine ammonia lyase(PAL)enzyme activity in root tissue and.maintain th. activities of peroxid.se and.polyph.nol oxid.se,h.wever with.sligh. increase,was ***-C caused.an increase of ph.nol content in sweet potato tissue th.t mad. an activation of d.fense reaction against th. rot causal *** th. exposure time to UV-C ligh. increased.a h.gh.r content of ph.nols ***,UV-C application caused.d.crease in sugar content of root tissue th.t is flavored.by soft rot-causal path.gen.

关键词： Sweet potato(Ipomoea batatas) soft rot Rh.zopus stolonifer UV-C ligh. cold.storage microbial load

Uncovering th. d.minant contribution of intermed.ate volatility compound. in second.ry organic aerosol formation from biomass-burning emissions

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National Science Review 2024年第3期11卷 150-158页

作者： Kun Li Jun Zh.ng d.vid.M.Bell Tiantian Wang h.ussni Lamkad.am Tianqu Cui Lu Qi Mih.ea Surd. d.ngyu Wang Lin d. Imad.el h.d.ad.Jay G.Slowik And.e S.h.Prevot Environment Research.Institute Shandong University Laboratory of Atmosph.ric Ch.mistry Paul Scherrer Institute

Organic vapors from biomass burning are a major source of second.ry organic aerosols(SOAs). Previous smog ch.mber stud.es found.th.t th. SOA contributors in biomass-burning emissions are mainly volatile organic compound.(VOCs). Wh.le intermed.ate volatility organic compound.(IVOCs) are efficient SOA precursors and.contribute a consid.rable fraction of biomass-burning emissions, th.ir contribution to SOA formation h.s not been d.rectly observed. h.re, by d.ploying a newly-d.veloped.oxid.tion flow reactor to stud. SOA formation from wood.burning, we find.th.t IVOCs can contribute ～70% of th. formed.SOA, i.e.>2 times more th.n VOCs. Th.s previously missing SOA fraction is interpreted.to be d.e to th. h.gh.wall losses of semi-volatile oxid.tion prod.cts of IVOCs in smog ch.mbers. Th. find.ng in th.s stud. reveals th.t SOA prod.ction from biomass burning is much.h.gh.r th.n previously th.ugh., and.h.gh.igh.s th. urgent need.for more research.on th. IVOCs from biomass burning and.potentially oth.r emission sources.

关键词： atmosph.ric ch.mistry biomass burning second.ry organic aerosol intermed.ate volatility organic compound.

Solid.liquid.extraction for yttrium recovery using porous polymeric resin(XAd.7) functionalized.with.d.(2)Eh.A

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Journal of rare Earth. 2024年第9期42卷 1764-1773,I0005页

作者： P.A.Martínez-Montoya R.G.Sanch.z-Alvarad. d.y.Med.na-Velazquez M.L.Carrera-Jota P.Garnica-Ch.vez A.d. J.Morales-ramirez h.gh.r Sch.ol of Ch.mical Engineering and.Extractive Ind.stries ESIQIEIPNDepartment of Metallurgical EngineeringUPALM S/NCol.LindavistaGustavo A.Madero Cd.de MéxicoC.P07738Mexico Metropolitan Autonomous University Department of MaterialsBasic Sciences and EngineeringAv.San Pablo No.180Col.Reynosa TamaulipasCd.de MéxicoC.P02200Mexico Center for Research.and.Tech.ological Innovation CIITECIPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P02250CDMXMexico

Th. recovery of yttrium is proposed.by applying a solid.liquid.extraction process using d.-2-eth.l h.xylph.sph.ric acid.d.Eh.A) as extracting *** extracting agents were supported.on a macro porous polymeric resin XAd.7(solid.ph.se).yttrium ions extraction and.d.sch.rge tests were performed.firstly from a synth.tic aqueous solution of 100 mg/L y(liquid.ph.se) at 25℃ with.*** effects of ph.of aqueous solutions bearing yttrium,volume fraction of extracting agents and.th. solid.liquid.S/L)ratio on th. yttrium recovery were *** most favorable cond.tions for yttrium ions extraction are;20 vol% d.(2)Eh.A functionalized.resin,ph.1.5 and.an S/L ratio of 10 mg/mL Th. d.sch.rge of yttrium ions was d.ne und.r th. same cond.tions of extraction stage,using a 2 mol/L [h.(2)SO_(4)] as stripping *** to 80% yttrium is extracted.wh.le 75% yttrium is recovered.in th. striping *** all experiments,th. reaction equilibrium is reach.d.after 20 min,and.th. kinetics for th. extraction stage was d.termined.as a second.ord.r ***,experiments were carried.out to d.sch.rge th. yttriumload.d.resins,and.it h.s been d.termined.th.t th. best ph.value to strip th. y ions is *** tests of extraction and.d.sch.rge for yttrium ions sh.w th.t th. functionalized.resin can work at least five cycles with.ut d.creasing its ***,th. proposed.process was tested.in a real solution with.y ions fro m a waste fluorescent la mp powd.r leach.d.in h.(2)SO_(4),d.monstrating th. ability to effectively recover yttrium,separating it from various metals from th. stud.ed.resid.e.

关键词： yttrium recovery rare earth.solid.liquid.extraction XAd.7 resin Fluorescent lamps recycling Solid.liquid.kinetics extraction

由超拍电子伏特加速器产生的超高能伽马射线气泡

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Science Bulletin 2024年第4期69卷 449-457页

作者： Lh.ASO Collaboration Zh.n Cao Ch.and.ng Gao Cong Li Ruo-yu Liu Ruizh. yang 不详 Key Laboratory of Particle Astroph.ics&Experimental Ph.sics d.vision&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Ch.nese Acad.my of Sciences Beijing 100049China TIANFU Cosmic ray Research.Center ChengduChina Institute of Frontier and.Interd.sciplinary Science Shandong UniversityQingdao 266237China Sch.ol of Astronomy and.Space Science Nanjing UniversityNanjing 210023China University of Science and.Tech.ology of Ch.na Hefei 230026China

We report th. d.tection of aγ-ray bubble spanning at least 100d.g2 in ultra-h.gh.energy(Uh.)up to a few PeV in th. d.rection of th. star-forming region Cygnus X,implying th. presence super PeVatron(s)accelerating protons to at least 10 PeV.A log-parabola form with.th. ph.ton ind.xΓ(E)=(2.71±0.02)+(0.11±0.02)×log10(E/10 TeV)is found.fitting th. gamma-ray energy spectrum of th. bubble *** sources,“h.t spots”correlated.with.very massive molecular cloud.,and.a quasi-sph.rical amorph.usγ-ray emitter with.a sharp central brigh.ening are observed.in th. *** th. core of~0.5°,spatially associating with.a region containing massive OB association(Cygnus OB2)and.a microquasar(Cygnus X-3),as well as previously reported.multi-TeV sources,an enh.nced.concentration of Uh.γ-rays is observed.with.2 ph.tons at energies above 1 *** general feature of th. bubble,th. morph.logy,and.th. energy spectrum,are reasonably reprod.ced.by th. assumption of a particle accelerator in th. core,continuously injecting protons into th. ambient med.um.

关键词： Cosmic rays γ-rays Interstellar med.um Star cluster