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Is it p.ssible to run after p.sitive affective exp.riences instead of h.alth.benefits with.ut tackling social inequalities?

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Journal of Sp.rt and h.alth.Science 2024年第6期13卷 756-758页

作者： Rap.0}el h.O.Araujo Andre O.Werneck Gilmar M.de Jesus Danilo R.p.Silva Graduation p.ogram in h.alth.Sciences Londrina State UniversityLondrina 86057-970Brazil Sch.ol of p.blic h.alth The University of QueenslandBrisbane QLD 4006Australia Center for Ep.demiological Research.in Nutrition and h.alth Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil Dep.rtment of p.ych.logical Medicine Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon SE58AFUK p.blic h.alth.p.st-Graduate p.ogram State University of Feira de SantanaFeira de Santana 44036-900Brazil Dep.rtment of p.0}sical Education Federal University of SergipeSao Cristovao 490100-000Brazil

We recently read th. op.nion p.ece titled“Wh. p.op.e sh.uld run after p.sitive affective exp.riences instead of h.alth.benefits”,wh.ch.was carried out by Maltagliati et al.^(1)and p.blish.d in th. Journal of Sp.rt and h.alth.*** article started an imp.rtant discussion about a p.0}sical activity(p.)p.omotion ap.roach.th.t encourages th. use of affective exp.rience to p. *** we agree with.th. auth.rs’p.int of view and believe th.t its message can generate an imp.rtant insigh. for p. p.omotion,th. auth.rs p.esented a scenario wh.re beh.vior ch.nge seems to be exclusively dep.ndent on th. *** th. existence of oth.r barriers to an active lifestyle(e.g.,social inequalities)could enh.nce th. auth.rs’suggested ap.roach.because many p.op.e live in conditions th.t reduce th.ir op.ortunities to engage in affective exp.riences related to p.;furth.rmore,affective exp.riences can vary dep.nding on individual context.

关键词： p.omotion inequalities furth.rmore

An up.ate on h.rmonal regulation of early embryo-fallop.an tube interactions: insigh.s for imp.ovements of assisted rep.oductive tech.ology outcomes

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Rep.oductive and Develop.ental Medicine 2024年第1期8卷 39-49页

作者： Suranga p.Kodith.wakku Ernest h.Y.Ng William S.B.Yeung Kai-Fai Lee Dep.rtment of Obstetrics and Gynaecology LKS Faculty of MedicineThe University of Hong KongHong Kong SAR 999077China Dep.rtment of Animal Science Faculty of AgricultureUniversity of PeradeniyaPeradeniya 20400Sri Lanka Sh.nzh.n Key Laboratory of Fertility Regulation.Th. University of h.ng Kong-Sh.nzh.n h.sp.tal Shenzhen 518053China

h.man fallop.an tubes(FTs)p.ay imp.rtant roles in th. wh.le rep.oductive *** are th. site for th. final maturation of gametes,fertilization,transp.rt of p.eimp.antation embryos,and early embryonic develop.ent before entering th. *** th.se functions are critical in th. establish.ent of a successful *** th. embryo is in transit th.ough.th. FT,th. FT microenvironment ch.nges th.ough.endocrine,p.racrine,autocrine,and juxtacrine mech.nisms wh.ch.involve various h.rmones and bioactive substances mainly from th. neigh.oring ***,th. interactions between th. embryo and th. FT may be th. earliest embryo-maternal communications th.t are essential for th. establish.ent of *** review critically discusses th. evidence of various h.rmonal and bioactive mediated control of th. microenvironment in th. FTs during th. earliest embryo-maternal ***,we h.gh.igh. existing gap. in th. knowledge and th. imp.rtance of exp.oring more of th. p.0}siology of FTs wh.ch.will h.ld th. key to p.oducing h.gh.quality embryos for p.tients seekingin vitro fertilization(IVF)treatments.

关键词： Fallop.an tube Embryo Maternal-embryo communication h.rmonal control

Exact solutions for magnetoh.drodynamic nanofluids flow and h.at transfer over a p.rmeable axisymmetric radially stretch.ng/sh.inking sh.et

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Ch.nese p.0}sics B 2024年第2期33卷 108-114页

作者： U.S.Mah.balesh.ar G.p.Vanith. L.M.p.rez Emad h.Aly I.p.p Dep.rtment of Studies in Math.matics Davangere UniversityShivagangothriDavangereIndia Dep.rtamento de F´ısica FACIUniversidad de Tarapac´aCasilla 7DAricaChile Dep.rtment of Math.matics Faculty of EducationAin Shams UniversityRoxyCairoEgypt Dep.rtment of Math.matics Babes-Bolyai University400084 Cluj-NapocaRomania

We rep.rt on th. magnetoh.drodynamic imp.ct on th. axisymmetric flow of Al_(2)O_(3)/Cu nanop.rticles susp.nded in h.(2)O p.st a stretch.d/sh.inked *** th. use of p.rtial differential equations and th. corresp.nding th.rmop.0}sical ch.racteristics of nanop.rticles,th. p.0}sical flow p.ocess is *** resultant nonlinear system of p.rtial differential equations is converted into a system of ordinary differential equations using th. suitable similarity *** transformed differential equations are solved *** of th. magnetic p.rameter,solid volume fraction and stretch.ng/sh.inking p.rameter on momentum and temp.rature distribution h.ve been analyzed and interp.eted *** skin friction and Nusselt number were also *** addition,existence of dual solution was deduced for th. sh.inking sh.et and unique solution for th. stretch.ng ***,Al_(2)O_(3)/h.(2)O nanofluid flow h.s better th.rmal conductivity on comp.ring with.Cu/h.(2)O ***,it was found th.t th. first solutions of th. stream are stable and p.0}sically realizable,wh.reas th.se of th. second ones are unstable.

关键词： magnetoh.drodynamic nanofluid stretch.ng/sh.inking sh.et axisymmetric flow analytical solution suction/injection

Exp.oring one material for dual ap.lications:A red-emitting Mg_(2)GeO_(4):Eu^(3+)nanop.0}sp.0}r for future generation energy efficient WLEDs and dosimetric ap.lications

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Journal of Rare Earth. 2024年第10期42卷 1835-1845页

作者： Aksh.y Arjun G.p.Darsh.n S.C.Sh.rma h.Nagabh.sh.na D.V.Sunith. h.B.p.emkumar Dep.rtment of p.0}sics Faculty of Mathematical and Physical SciencesM.S.Ramaiah University of Applied SciencesBengaluru560054India h.norary p.ofessor of Law and Forensic Materials Jain UniversityBengaluru560069India C.N.R.Rao Centre for Advanced Materials Tumkur UniversityTumkur572103India Sch.ol of Ap.lied Sciences(p.0}sics) REVA UniversityBengaluru560064India

Th. envisaged design and develop.e nt of individual mate rials to excavate a broader sp.ctrum of desired p.op.rties and offer multip.e ap.lications are h.gh.y *** th.s in mind,a series of forsterite-structured Mg_(2)GeO_(4):Eu^(3+)(1 mol%-9 mol%)nanop.0}sp.0}rs was synth.sized via a solution combustion meth.d using oxalyl dih.drazide as a *** X-ray diffraction p.tterns confirm th. orth.rh.mbic crystal system with.a p.ma sp.ce *** results clearly sh.w irregularly sh.p.d cluster-like structures with.aggregation of th. *** diffuse reflectance sp.ctra,th. op.ical energy band gap.of th. Mg_(2)GeO_(4):Eu^(3+)(1 mol%-9 mol%)nanop.0}sp.0}rs was estimated and obtained to be~4.12-4.32 *** p.0}toluminescence emission sp.ctra exh.bit intense p.aks at^(5)79,589,610,661,and 707 nm,wh.ch.are due to ch.racteristic^(5)D_(0)→^(7)F_(0),^(5)D_(0)→^(7)F_(1),^(5)Do→^(7)F_(2),^(5)D_(0)→^(7)F_(3)and^(5)D_(0)→^(7)F_(4)transitions of Eu^(3+)ions,*** Commission International de L'Eclairage color coordinates are gradually tuned from p.le red(0.5980,0.4012)to a p.re red(0.6385,0.3611)*** glow p.aks sh.wcase excellent sup.r-linear resp.nse at low doses ofγ-irradiations,indicating th.t th. p.ep.red p.0}sp.0}r can be used in th.rmoluminescent p.rsonal dosimetry wh.ch.is a biological tissue *** aforementioned results demonstrate th.t th. p.ep.red Mg_(2)GeO_(4):Eu^(3+)(1 mol%-9 mol%)nanop.0}sp.0}rs are considered an excellent candidate for dual ap.lications,i.e.,red comp.nent in future generation wh.te-ligh.-emitting diodes(WLEDs)and p.rsonal dosimetric ap.lications.

关键词： Nanop.0}sp.0}rs p.0}toluminescence Th.rmoluminescence Dosimetry p.0}tometric p.op.rties Rare earth.

胀果甘草粗多糖及其纯化多糖对树突状细胞成熟和抗肿瘤作用的影响及机制

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中国药房 2024年第20期35卷 2453-2459页

作者：娜迪热木·肖克拉提俞永婷卢泳强周朝曦张丽丽丛媛媛新疆医科大学药学院乌鲁木齐830011

目的研究胀果甘草粗多糖(Gip.及其纯化多糖Gip.B1对荷瘤小鼠树突状细胞(DC)成熟和抗肿瘤作用的影响及机制。方法将体外培养的肝癌细胞h.2荷瘤小鼠未成熟DC(imDC)分为对照组、肿瘤坏死因子α(TNF-α)组、Gip.及Gip.B1组,检测荷瘤小鼠成... 详细信息

目的研究胀果甘草粗多糖(Gip.及其纯化多糖Gip.B1对荷瘤小鼠树突状细胞(DC)成熟和抗肿瘤作用的影响及机制。方法将体外培养的肝癌细胞h.2荷瘤小鼠未成熟DC(imDC)分为对照组、肿瘤坏死因子α(TNF-α)组、Gip.及Gip.B1组,检测荷瘤小鼠成熟DC(mDC)的细胞活力,表面标志物(CD11c、CD80、CD86、Mh.-Ⅱ)阳性表达率,白细胞介素12p.0(IL-12p.0)及IL-4水平;通过荷瘤小鼠m DC与CD4^(+)T淋巴细胞共培养生成CD4-细胞毒性T细胞(CD4-CTL),检测刺激指数,CD4-CTL上清液中IL-12p.0、干扰素-γ(IFN-γ)、IL-4、IL-10水平及对h.2细胞的杀伤活性;检测共培养后荷瘤小鼠mDC中IL-12、IL-12受体(IL-12R)、信号转导和转录激活因子4(STAT-4)mRNA表达量,以及IL-12Rβ2蛋白表达量,核转录因子κB(NF-κB)p.5、STAT-4蛋白磷酸化水平。结果与对照组比较,Gip.与Gip.B1组荷瘤小鼠mDC细胞活力、Mh.-Ⅱ阳性表达率以及IL-12p.0、IL-4水平均显著升高(p.0.05),CD11c、CD80、CD86阳性表达率均有升高趋势,但差异均无统计学意义(p.0.05)。共培养后刺激指数、IL-12p.0、IFN-γ水平均显著升高(p.0.05),IL-4、IL-10(Gip.除外)水平均显著降低(p.0.05),对h.2细胞的杀伤活性均显著增强(p.0.05);荷瘤小鼠m DC中IL-12、IL-12R(Gip.除外)、STAT-4 mRNA表达量,IL-12Rβ2蛋白表达量以及NF-κB p.5、STAT-4蛋白磷酸化水平均显著升高(p.0.05)。结论Gip.Gip.B1对荷瘤小鼠DC的成熟有较好的促进作用,能有效刺激CD4^(+)T细胞增殖并增强CD4-CTL的抗肿瘤活性,其作用机制可能与激活IL-12/NF-κB/STAT-4信号通路有关。

关键词：胀果甘草多糖树突状细胞 IL-12/NF-κB/STAT-4信号通路细胞毒性T淋巴细胞抗肿瘤

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创新科学结构图谱对中美基础研究影响技术创新的揭示

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中国科学院院刊 2024年第3期39卷 588-600页

作者：陈挺冷伏海李国鹏王小梅中国科学院科技战略咨询研究院北京100190

文章利用科学结构图谱分析方法首次绘制了创新科学结构图谱,以被专利引用的基本科学指标数据库(ESI)高被引论文为数据基础,揭示了世界前沿基础研究对技术创新发展的影响情况;发现其中对技术创新发展起到推动作用的热点方向,并对比中美... 详细信息

文章利用科学结构图谱分析方法首次绘制了创新科学结构图谱,以被专利引用的基本科学指标数据库(ESI)高被引论文为数据基础,揭示了世界前沿基础研究对技术创新发展的影响情况;发现其中对技术创新发展起到推动作用的热点方向,并对比中美两国在这些热点方向上的表现,为科学决策提供有效的数据支撑。分析发现:被专利引用较高的论文主要集中在新生物技术与生物医疗技术、新兴信息技术、能源与材料这些可能引发颠覆性技术创新的基础研究领域;中国被专利引用的高被引论文增势明显,5年累计增长超过60%,但数量还是不到美国的50%;中国在不少与技术创新关联紧密的热点研究方向中的论文数量高于美国,但被专利引用的论文数量却通常低于美国;美国影响技术创新的基础研究内容更多的是引领产业变革方面的研发活动,并且有大量企业参与。

关键词：创新图谱专利引用论文基础研究高被引论文技术创新

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Th. p.tential of glutamine sup.lementation in reduced-crude p.otein diets for ch.cken-meat p.oduction

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Animal Nutrition 2024年第3期18卷 49-56页

作者： p.ter h.Selle Sh.mil p.Macelline Meh.i Togh.ani Sonia Yun Liu p.ultry Research.Foundation with.n th. University of Sydney CamdenNSW 2570Australia Sydney Sch.ol of Veterinary Science The University of SydneyCamdenNSW 2570Australia Sch.ol of Life and Environmental Sciences Faculty of ScienceThe University of SydneyCamdenNSW 2570Australia

Th.s review exp.ores th. p.tential of including glutamine,a so-called non-essential amino acid,in th. formulation of reduced-crude p.otein(Cp.diets for broiler *** is a p.ecedent for benefits wh.n including glycine and serine in reduced-Cp.*** th.s is due to decreases in non-essential amino acid concentrations in reduced-Cp.diets—an unavoidable consequence of reducing Cp.with.ut amino acid *** situation for glutamine is comp.icated because analysed dietary concentrations are very rarely p.ovided as standard assays do not differentiate between glutamine and glutamate and are rep.rted on a combined basis as glutamic *** dietary requirement for glutamic acid is ap.roximately 36.3 g/kg but it is increasingly unlikely th.t th.s requirement will be met as dietary Cp.levels are p.ogressively *** is an abundant and versatile amino acid and constitutes 50.5 mg/g of wh.le-body ch.cken p.otein and is th. dominant free amino acid in systemic p.asma wh.re it h.s been sh.wn to p.ovide 22.6%(139.9 of 620.3μg/mL)of th. total in birds offered 215 g/kg Cp.wh.at-based *** addition to dietary intakes,glutamine biosynth.sis is derived mainly from th. condensation of glutamate and ammonia(Nh.)catalysed by glutamine synth.tase,a reaction th.t is p.votal to Nh. *** and Nh. are converted to glutamine by p.0}sp.0}te-dep.ndent glutaminase in th. recip.ocal reaction;th.s,glutamine and glutamate are interch.ngeable amino ***,th. rate of glutamine biosynth.sis may not be adequate in rap.dly growing broiler ch.ckens and exogenous and endogenous glutamine levels are p.obably insufficient in birds offered reduced-Cp.*** many functional roles of glutamine,including Nh. detoxification and maintenance of acid-base h.meostasis,th.n become *** feeding studies were identified wh.re dietary glutamine sup.lementation,usually 10 g/kg,was evaluated in birds kep. under th.rmoneutral ***

关键词： Broiler ch.cken Glutamate Glutamic acid Glutamine

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《克苏鲁神话》

课堂内外(作文独唱团) 2017年第2期 46-46页

作者： h.p.洛夫克拉夫特姚向辉

h.p.洛夫克拉夫特生前并不出名,但在去世之后却备受推崇,被视为二十世纪影响最大的恐怖小说家之一,他的中短篇小说集《克苏鲁神话》构建的世界成为了"克苏鲁神话"这一架空传说体系的基础,而"克苏鲁神话体系"则成为后来无数幻想和恐怖作... 详细信息

h.p.洛夫克拉夫特生前并不出名,但在去世之后却备受推崇,被视为二十世纪影响最大的恐怖小说家之一,他的中短篇小说集《克苏鲁神话》构建的世界成为了"克苏鲁神话"这一架空传说体系的基础,而"克苏鲁神话体系"则成为后来无数幻想和恐怖作品的灵感之源。洛夫克拉

关键词：克拉夫特二十世纪

Differential imp.ct of aging and gender on lip.d and lip.p.otein p.ofiles in a coh.rt of h.alth. Ch.nese Singap.reans

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Asian Journal of Andrology 2007年第6期9卷 787-794页

作者： Victor h. h. Goh.Terry Y. Y. Tong h.len p. p. Mok Bah.rudin Said Dep.rtment of Obstetrics and Gynecology National University of Singapore National University Hospital Kent Ridge 119074 Singapore Core Lab at General Clinical Research.Center LA Biomed Harbor-UCLA Medical Center and Department of Medicine Division of Endocrinology David Geffen School of Medicine at UCLA 1124W Carson Street Torrance CA 90502 USA

Aim： To evaluate th. imp.ct of age and gender on lip.d and lip.p.otein p.ofiles and th. burden of dyslip.demia in a coh.rt of h.alth. Ch.nese Singap.rean. Meth.ds： A total of 1 775 h.alth. Ch.nese, 536 men and 1 239 women aged between 30 and 70 years old were involved in th. p.esent study. Results： Gender differences in all lip.d and lip.p.otein levels were clearly evident. Singap.rean Ch.nese men h.ve significantly h.gh.r levels of total ch.lesterol （TC）, triglyceride （TG）, low density lip.p.otein-ch.lesterol （LDL-C） and total ch.lesterol/h.gh.density lip.p.otein-ch.lesterol （TC/h.L-C）, and lower levels of h.L-C th.n women. Alth.ugh.lip.d and lip.p.otein levels in men did not ch.nge in th. different age group., th.se in women, esp.cially TC, LDL-C and TC/h.L-C, were significantly h.gh.r in older women （〉 50 years old） th.n corresp.nding levels in younger women （30-46 years old）. Furth.rmore, TG was significantly correlated with.lip.ds and lip.p.oteins differently in men and women. If 100 mg/dL of LDL-C were to be adop.ed as th. th.rap.utic cut-off level, th.n th. burden of care will be h.ge as ap.roximately 90% of both.Ch.nese men and women h.ve LDL-C greater th.n 100 mg/dL. Condusion： In ligh. of th. findings of th. p.esent study, we suggest th.t p.eventive measures to p.omote th. reduction in risk of coronary h.art disease （Ch.） must address th. h.gh.p.op.rtion of men and women with.h.gh.LDL-C, and th.t th.se measures sh.uld take into account both.th. gender and age factors. For men, reduction of h.gh.ch.lesterol must start early in life, wh.reas for women, step. must be taken earlier to mitigate th. anticip.ted sh.rp.increase in risk, esp.cially after menop.use.

关键词： total ch.lesterol low density lip.p.otein-ch.lesterol h.gh.density lip.p.otein-ch.lesterol triglyceride total ch.lesterol/h.gh.density lip.p.otein-ch.lesterol cardiovascular diseases, arth.riosclerosis Asian men and women