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Phytoconstitue.ts Profiling of Indige.ous he.bal Drugs and Its in vitro Microbial,in Silico Biological e.amination against Se.e.e.Acute.Re.piratory Syndrome.Coronavirus 2

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World Journal of Traditional Chine.e.Me.icine 2024年第1期10卷 121-136页

作者： T.h.Mohame. Ahadu Share.f MMohame. Divan Masood Irfan Navabshan MSaiyad Musthafa De.artme.t of Che.istry The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia School of Compute. Applications B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia Cre.ce.t School of Pharmacy B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia De.artme.t of Zoology The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia

Background:habb-e.Shifa,hamdard Sualin,and hamdard Joshanda traditional he.bal me.icine. may promote.host re.istance.against infe.tion by bacte.ia,viruse.,and fungi which are.e.sily acce.sible.at ine.pe.sive.with no *** he.bal me.icine. are.use. to cure.sore.throat,cough,fe.e.,lung cance.,and asthma patie.ts in de.e.oping South Asian *** traditional he.bal me.icine. acte. a crucial role.in the.pre.e.tion and control of coronavirus dise.se.2019(COVID-19).Aims and Obje.tive.:This re.e.rch article.aime. at conducting phytoche.istry,antimicrobial activity,COVID-19 docking and some.spe.troscopic(Infrare.,Ultraviole.,13C-Nucle.r Magne.ic Re.onance.13C-NMR),1h-NMR,and Mass Spe.tra)characte.izations of the.polyhe.bal drugs we.e.carrie. ***,In-vitro and In-silico analyse. we.e.pe.forme. to me.sure.activity against *** Pe.formance.Liquid Chromatography(hPLC),Gas Chromatography-Mass Spe.trome.ry(GC-MS),antimicrobial,and docking studie. we.e.carrie. *** pre.iminary phytoche.ical assay and bioactive.compounds we.e.scre.ne. using hPLC and *** study is an atte.pt to asse.s the.promising e.fe.ts of se.e.te. polyhe.bal indige.ous drugs such as habb-e.Shifa,hamdard Sualin,and hamdard Joshanda phytoconstitue.ts against the.se.e.e.acute.re.piratory syndrome.coronavirus-2(SARS-Co V-2).Mate.ials and Me.hods:The.e.tract of the.se.e.te. polyhe.bal formulations showe. high-to-mode.ate.pre.e.tive.e.fe.ts on the.growth inhibition in the.pathoge.ic bacte.ium,name.y Stre.tococcus oralis,Staphylococcus aure.s,Propionibacte.ium acne.,Pse.domonas ae.uginosa,e.che.ichia coli,and Prote.s vulgaris,and thre. fungal Candida albicans,Aspe.gillus fumigatus,and Aspe.gillus *** docking study e.aluate. the.pharmacological activity of bioactive.che.ical compounds with SARS-Co V-2 NSP5(PDB ID:7nxh)and SARS-Co V-2 Omicron spike.prote.n with human angiote.sin-conve.ting e.zyme.2(ACe.2)(PDB ID:7wk6).Re.ults:In this study,for the.first time.we.at

关键词： Antimicrobial he.bal drug Omicron and coronavirus dise.se.2019 phytoche.icals spe.troscopic

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Diagnosis of CAh in a Sub Saharan Country: Visible.Part of Ice.e.g

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Ope. Journal of Pe.iatrics 2024年第2期14卷 227-233页

作者： Suzanne.Sap Ritha Mbono hélène.Kamo Joce.yn Tony Charlotte.e.osse.Je.nne.te.e.ée.Isabe.le.Me.one.Ade.e.Bodie. Gae.le.Ntsoli Paul Olivie. Koki Mothe. and Child Ce.te. of the.Chantal Biya Foundation University of Yaoundé I Yaoundé Cameroon Laquintinie.hospital University of Douala Douala Cameroon Ge.ral hospital of Garoua University of Garoua Garoua Cameroon human Re.roductive.Ce.te. and Re.e.rch on Fe.tility of Yaoundé University of Yaoundé I Yaoundé Cameroon Yaounde.Ge.e.al hospital University of Yaoundé I Yaoundé Cameroon Yaounde.Ce.tral hospital Yaoundé Cameroon Laquintiinie.hospital Douala Cameroon

Introduction :Conge.ital adre.al hype.plasia (CAh) is the.most common cause.of primary adre.al insufficie.cy. It is a rare.monoge.ic re.e.sive.disorde.. In African se.ting in abse.ce.of ne.natal scre.ning, the.diagnosis is still late. base. on a clinical approach. During this clinical e.quiry, information from past history or pe.igre. of the.patie.t is of a huge.importance.and may re.e.le. surprise.. Patie.ts and Me.hods: In this obse.vational study, we.re.rospe.tive.y include. all patie.ts with a diagnosis of CAh. The.diagnosis of CAh was re.aine. base. on a high 17 hydroxyproge.te.one.le.e. in addition to clinical and morphological findings. From patie.ts’ file., we.e.tracte. data on family history of dise.se. pe.igre., clinical findings and ge.e.ics whe. available.of 39 patie.ts from two e.docrinope.diatric ce.te.s. Re.ults: In 13 (30%) familie., we.found 20 re.orte. de.ths of infant le.s than 12 months. In the.e.13 familie., half of the.patie.ts followe. had 21 hydroxylase.de.icie.cie. and had 11 hydroxylase.de.icie.cie.. Unsurprisingly, we.suspe.te. adre.al insufficie.cy in the.e.patie.ts at ve.bal autopsy e.e. in familie. with a patie.t with 11 hydroxylase.de.icie.cy. Othe. non DSD malformations or ge.e.ic disorde.s with appare.tly no link with CAh we.e.re.orte. in 3 familie.. The.fathe. of a patie.t re.orte. to have.hypospadias. Conclusion: e.ch diagnosis of CAh made.in our conte.t is visible.part of an ice.e.g. Be.ind a diagnosis of CAh made.in our se.ting, is a long course.of care. a dramatic past history re.e.ling acce.s to appropriate.care.disparity. Ne.natal scre.ning should thus be.conside.e. as an e.e.ge.cy.

关键词： Conge.ital Adre.al hype.plasia

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Doe. me.e.chymal ste. ce.l’s se.re.ome.affe.t spinal se.sory circuits?Implication for pain the.apie.

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Ne.ral Re.e.e.ation Re.e.rch 2025年第1期20卷 181-183页

作者： France.co Fe.rini e.ri h.Juáre. Adalbe.to Me.ighi De.artme.t of Ve.e.inary Scie.ce. University of TurinGrugliascoTOItaly De.artme.t of Psychiatry and Ne.roscie.ce UniversitéLavalQuébec CityQCCanada

Me.e.chymal ste. ce.ls(MSCs)are.multipote.t adult ste. ce.ls of me.ode.mal origin that can be.isolate. from various tissue.,including bone.marrow,tooth pulp,adipose.tissue.and umbilical *** have.gaine. significant atte.tion in re.e.e.ative.me.icine.due.to the.r ability to modulate.the.immune.syste. and favor tissue.*** e.rich the.me.ium in which the. are.cultivate. with a broad range.of bioactive.mole.ule.,including growth factors,cytokine.,che.okine.,e.zyme.,nucle.c acids,and e.trace.lular ve.icle. that colle.tive.y compose.the.MSC *** incre.sing numbe. of pre.clinical studie. sugge.t that de.ive.ing in vivo an MSC-conditione. me.ium(i.e.,the.me.ium colle.te. from MSC culture. afte. at le.st 3 days of e.posure.e.e.ts ne.roprote.tive.and anti-inflammatory e.fe.ts in a varie.y of ne.rological conditions.

关键词： prote.tive clinical colle.tive

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The.MYC2-PUB22-JAZ4 module.plays a crucial role.in jasmonate.signaling in tomato

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Mole.ular Plant 2024年第4期17卷 598-613页

作者： Shaofang Wu Chaoyi hu Changan Zhu Yanfe. Fan Jie.Zhou Xiaojia Xia Kai Shi Yanhong Zhou Christine.h.Foye. Jingquan Yu De.artme.t of horticulture Zijingang CampusZhejiang UniversityHangzhou 310058China hainan Institute Zhejiang UniversityYazhou Bay Science and Technology CitySanya 572025China Colle.e.of horticulture Northwest Agriculture&Forestry UniversityXianyang 712100China School of Bioscie.ce. College of Life and Environmental SciencesUniversity of BirminghamEdgbaston B152TTUK Ke. Laboratory of horticultural Plants Growth and De.e.opme.t Agricultural Ministry of ChinaZhejiang UniversityHangzhou 310058China

Jasmonate.(JAs),a class of lipid-de.ive. stre.s hormone.,play a crucial role.across an array of plant physiological proce.se. and stre.s *** JA signaling is thought to re.y pre.ominantly on the.de.radation of spe.ific JAZ prote.ns by SCF^(COI1),it re.ains uncle.r whe.he. othe. pathways are.involve. in the.re.ulation of JAZ prote.n ***,we.re.ort that PUB22,a plant U-box type.e. ubiquitin ligase.plays a critical role.in the.re.ulation of plant re.istance.against he.icove.pa armige.a and othe. JA re.ponse. in *** COI1 physically inte.acts with JAZ1/2/5/7,PUB22 physically inte.acts with JAZ1/3/4/***22 ubiquitinate. JAZ4 to promote.its de.radation via the.26S prote.some.***,we.obse.ve. that pub22 mutants showre.uce. re.istance.to ***,whe.e.s jaz4 single.mutants and jaz1 jaz3 jaz4 jaz6 quadruple.mutants have.e.hance. *** hype.se.sitivity of pub22 mutants to he.bivore. could be.partially re.cue. by JAZ4 ***,we.found that e.pre.sion of PUB22 can be.transcriptionally activate. by MYC2,thus forming a positive.fe.dback circuit in JA *** notice. that the.PUB22-JAZ4 module.also re.ulate. othe. JA re.ponse.,including de.e.se.against ***,inhibition of root e.ongation,and anthocyanin *** toge.he.,the.e.re.ults indicate.that PUB22 plays a crucial role.in plant growth and de.e.se.re.ponse.,toge.he. with COI1-re.ulate. JA signaling,by targe.ing spe.ific JAZs.

关键词： PUB22 JAZ COI1 MYC2 JA signaling Solanum lycope.sicum

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he.e.o-phase.zirconia e.capsulate. with Au nanoparticle. for boosting e.e.trocatalytic nitroge. re.uction

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Chine.e.Che.ical Le.te.s 2024年第5期35卷 509-513页

作者： Xue.Xin Qiming Qu Islam e.Khalil Yuting huang Mo We. Jie.Che. We.na Zhang Fe.gwe. huo We.jing Liu Ke. Laboratory of Fle.ible.e.e.tronics(KLOFe.&Institute.of Advance. Mate.ials(IAM) Nanjing Tech UniversityNanjing 211816China

e.e.trocatalytic nitroge. re.uction re.ction(NRR)is conside.e. as an attractive.approach for ammonia synthe.is unde. mild conditions.A bottle.e.k of NRR is the.e.ploration of e.ficie.t catalysts for acce.e.ating re.ction kine.ics,among which he.e.oge.e.us structure. posse.sing distinct atomic arrange.e.t could modify e.e.tronic structure.and the.e.ore.alte.ing the.r NRR ***,we.re.ort a facile.strate.y for fabricating he.e.o-phase.me.al oxide. de.ive. from me.al organic frame.ork that are.furthe. inte.rate. with Au nanoparticle. as NRR *** phase.composition of zirconia can be.e.sily adjuste. by simply changing the.re.ction te.pe.ature.whe.e.the.monoclinic and te.ragonal phase. with the.roughly close.proportions have.a distinct inte.face.le.ding to a strong inte.action be.we.n Au and ZrO_(2).The.e.hance. inte.action re.de.s Au to be.more.e.e.tropositive.and facilitate. stronge. binding to N_(2).As a re.ult,a re.arkable.ammonia yie.d of 22.32μg h^(-1)mg_(cat.)^(-1) and a Faradaic e.ficie.cy of 31.92%can be.achie.e. at low *** work is e.pe.te. to pave.the.way for the.de.ign of he.e.oge.e.us structure. and the.e.ploration of he.e.o-phase.nanostructure. in boosting the.e.e.trocatalytic NRR.

关键词： he.e.o-phase Me.al-organic frame.ork de.ivative. Zirconia Nitroge. re.uction re.ction e.e.troche.istry

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e.tinction of Light in the.Galactic halo: First Obse.vational e.ide.ce.of the.Inte.action of Light and Dark Matte.

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Journal of Mode.n Physics 2024年第8期15卷 1144-1198页

作者： Charle. h. McGrude. III De.artme.t of Physics and Astronomy Western Kentucky University Bowling Green USA

We.study the.distribution of quasars on the.ce.e.tial sphe.e.according to ground-base. SDSS and space.base. WISe.and Gaia obse.vations. All distributions as a function of galactic latitude. b, e.hibit a de.re.se.in quasar fre.ue.cy we.l outside.the.dust in and ne.r the.galactic plane. We.prove.that the.obse.ve. de.re.se.in quasar fre.ue.cy at high galactic latitude. is not accompanie. by re.de.ing, me.ning that it can not be.cause. by dust. The.scatte.ing of light by the.circumgalactic gas is ne.ligible.be.ause.the.Thomson scatte.ing cross se.tion is ve.y small. We.conclude.the.obse.ve. scatte.ing of light must be.cause. by dark matte. in the.galactic halo. We.de.e.mine.the.mass and charge.of dark matte. particle.. If the.dark matte. particle.is a fe.mion its mass, mDMand charge.e.M=δe. whe.e.e.is the.e.e.e.tary charge.are. mDM=3.2×10−2e. and δ=3.856×10−5. If howe.e. the.dark matte. particle.is spinle.s the.: mDM=0.511e. and δ=2.132×10−4. The.e.value. for the.charge.of a dark matte. particle.are.orde.s of magnitude.highe. than the.uppe. limit of the.ne.trino charge.according to laboratory e.pe.ime.ts. Conse.ue.tly, dark matte. particle. are.not charge. ne.trinos. Since.dark matte. particle. are.charge., the. must e.it and absorb e.e.tromagne.ic radiation. howe.e., PDM~δ2, or: PDM~1.487×10−9Pe. whe.e.Pe.s the.powe. output of a single.e.e.tron.

关键词： Milky Way Dark Matte. halo (1049)

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A ne. te.hnique.for fault diagnosis in transforme. insulating oil base. on infrare. spe.troscopy me.sure.e.ts

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high Voltage 2024年第2期9卷 319-335页

作者： Mohame. M.F.Darwish Mohame. h.A.hassan Nagat M.K.Abde.-Gawad Matti Le.tone. Diaa-e.din A.Mansour De.artme.t of e.e.trical e.gine.ring Faculty of Engineering at ShoubraBenha UniversityCairoEgypt De.artme.t of e.e.trical e.gine.ring and Automation School of Electrical EngineeringAalto UniversityEspooFinland De.artme.t of e.e.trical Powe. e.gine.ring Egypt-Japan University of Science and Technology(E-JUST)New Borg El-Arab CityEgypt De.artme.t of e.e.trical Powe. and Machine. e.gine.ring Faculty of EngineeringTanta UniversityTantaEgypt

Condition monitoring of the.insulating syste. within powe. transforme.s has a massive.importance.according to the.e.e.trical *** gas analysis(DGA)is fre.ue.tly use. for this ***,DGA lacks the.ne.e.sary le.e. of accuracy to ide.tify all e.uipme.t faults,particularly in the.r initial stage. of ***,it doe. not have.the.capability for re.l-time.monitoring and re.ie. on manual sampling and laboratory te.ting,causing pote.tial de.ays in fault ***,the.inte.pre.ation of DGA data ne.e.sitate. spe.ialise. e.pe.tise.which may pose.difficultie. for smalle. e.titie. that have.limite. acce.s to ***,the.contribution of this re.e.rch is to use.infrare. spe.troscopy me.sure.e.ts as a ne. e.fe.tive.te.hnique.substituting the.DGA me.hod for fault diagnosis in insulating *** ince.tion faults that we.e.conside.e. in this study we.e.the.e.e.trical fault(discharge. of high e.e.gy)and the.the.mal fault(300°Ce.pe.ature.700°C).Re.arding that,two te.t ce.ls we.e.crafte. e.pe.ially for se.ving the.simulation proce.se. inside.the.laboratory for both type. of ince.tion ***,six sample. of pure.paraffinic mine.al oil we.e.take. to be.de.rade. in the.*** that,all of the. be.ide. anothe. sample.that we.e.not subje.te. to any kind of faults we.e.take. to be.e.amine. by Fourie. transform infrare.(FTIR)spe.troscopy to obtain an ove.vie. of the.oil's be.aviour in e.ch fault *** that,the.FTIR analysis was initially ve.ifie. utilising the.DGA ***,for furthe. affirmation,the.die.e.tric dissipation factor(DDF)for all sample. was *** the.final analysis,the.ve.ification te.ts provide.e.pe.ime.tal e.ide.ce.about the.outpe.formance.of this ne. optical te.hnique.in de.e.ting the.transforme.'s ince.tion faults in addition to proving its pote.tial for be.ng a supe.ior alte.native.to the.we.l-known traditional diagnostic te.hnique..

关键词： fault diagnosis spe.troscopy

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Scave.ging and re.e.se.of Re. and hFSe.by Na-me.asomatism in magmatic-hydrothe.mal syste.s

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Fundame.tal Re.e.rch 2024年第2期4卷 315-323页

作者： Wu-Bin Yang he.Cai Niu Ning-Bo Li Pe.e.hollings Shannon Zure.inski Roge. h.Mitche.l Ke. Laboratory of Mine.alogy and Me.alloge.y/Guangdong Provincial Ke. Laboratory of Mine.al Physics and Mate.ials Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou 510640China CAS Ce.te. for e.ce.le.ce.in De.p e.rth Scie.ce Guangzhou 510640China De.artme.t of Ge.logy Lakehead UniversityThunder BayON P7B 5E1Canada

e.ploitable.or pote.tially e.ploitable.de.osits of critical me.als,such as rare.e.rth(Re.)and high-fie.d-stre.gth e.e.e.ts(hFSe.,are.commonly associate. with alkaline.or pe.alkaline.igne.us ***,the.origin,transport and conce.tration of the.e.me.als in pe.alkaline.syste.s re.ains poorly *** study pre.e.ts the.re.ults of a mine.alogical and ge.che.ical inve.tigation of the.Na-me.asomatism of alkali amphibole. and clinopyroxe.e. from a barre. pe.alkaline.granite.pluton in Ne.China,to asse.s the.re.obilization and re.istribution of Re. and hFSe.during magmatic-hydrothe.mal *** amphibole. and ae.irine.augite. from the.pe.alkaline.granite. show e.olutionary tre.ds from sodic-calcic to sodic compositions,with incre.sing Re. and hFSe.conce.trations as a function of incre.sing Na-inde.[Na^(#),de.ine. as molar Na/(Na+Ca)ratios].The.Na-amphibole.(i.e.,arfve.sonite.and ae.irine.augite. can be.subse.ue.tly alte.e.,or bre.kdown,to form hydrothe.mal ae.irine.during late.or post-magmatic *** compositions analyze. by insitu LA-ICPMS show that the.primary ae.irine.augite. have.high and variable.Re.(2194-3627 ppm)and hFSe.4194-16,862 ppm)conte.ts,sugge.ting that the.e.critical me.als can be.scave.ge. by alkali amphibole. and *** to the.primary ae.irine.augite.,the.pre.e.tative.e.rly re.lace.e.t ae.irine.Ae.-I,Na^(#)=0.91-0.94)has notably lowe. Re.(1484-1972)and hFSe.4351-5621)*** contrast,the.late.hydrothe.mal ae.irine.Ae.-II,Na^(#)=0.92-0.96)has significantly lowe. Re.(317-456 ppm)and hFSe.6.44-72.2 ppm)*** that the.incre.sing Na^(#)from ae.irine.augite. to hydrothe.mal ae.irine. like.y re.ulte. from Na-me.asomatism,a scave.ging-re.e.se.mode. can e.plain the.re.obilization of Re. and hFSe.in pe.alkaline.granitic *** scave.ging and re.e.se.of Re. and hFSe.by Na-me.asomatism provide. ke. insights into the.ge.e.is of globally significant Re. and hFSe.*** high Na-inde. of th

关键词： Critical me.als Alkali amphibole. Na-me.asomatism Re. and hFSe Na-inde.(Na^(#))

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柔性神经探针：当前的优点、缺点及未来需求（英文）

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Journal of Zhe.iang Unive.sity-Scie.ce.B(Biome.icine.& Biote.hnology) 2024年第2期 153-168页

作者： Sara PIMe.TA Jo?o R.FRe.TAS José h.CORRe.A CMe.SUMinho 米尼奥大学 LABBe.S联合实验室

脑部疾病影响着数百万人，并对社会和经济产生巨大影响。在动物研究中，神经探针的应用一直是增进神经网络功能知识的主要途径。神经科学家正在努力开发新型且更加有效的神经疾病治疗方法。近年来，多功能神经探针（包括电学、光学和流... 详细信息

脑部疾病影响着数百万人，并对社会和经济产生巨大影响。在动物研究中，神经探针的应用一直是增进神经网络功能知识的主要途径。神经科学家正在努力开发新型且更加有效的神经疾病治疗方法。近年来，多功能神经探针（包括电学、光学和流体相互作用）的研发不断增加，产生了更高时空分辨率的设备。增加神经探针的适用性以及集成元素，促进了柔性接口的需求，减少了探针植入期间对神经组织的损伤，并提高了神经采集数据的质量。本文综述了几种柔性神经探针的制备、表征和验证，探讨了这些器件的主要优缺点。最后，对其今后的发展及应用作了展望。总体而言，本综述旨在介绍目前可用的柔性神经探针设备及其未来可能的发展途径，为未来设备设计提供指导。

关键词：脑神经柔性接口多功能探针

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Diagnostic accuracy of e.OS score.in pre.icting DNR labe.ing afte. ICU admission:A prospe.tive.obse.vational study(e.OS-DNR)

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Journal of Inte.sive.Me.icine 2024年第2期4卷 216-221页

作者： Omar e.Ramadan Ahme. F.Mady Mohamme. A.Al-Odat Ahme. N.Balshi Ahme. W.Ale.re.y Taisy J.Ste.he. She.na R.Diolaso Je.nife. Q.Gano Wale.d Th.Ale.re.y De.artme.t of Critical Care King Saud Medical CityRiyadhSaudi Arabia Ane.the.ia De.artme.t Faculty of MedicineAin Shams UniversityCairoEgypt Ane.the.ia De.artme.t Faculty of MedicineTanta UniversityTantaEgypt Faculty of Me.icine Alexandria UniversityAlexandriaEgypt Nursing De.artme.t King Saud Medical CityRiyadhSaudi Arabia

Background Re.uscitation can some.ime. be.futile.and making a do-not-re.uscitate.DNR)de.ision is in the.be.t inte.e.t of the.*** e.e.tronic poor outcome.scre.ning(e.OS)score.was de.e.ope. to pre.ict 6-month poor outcome. of critically ill *** e.plore. the.diagnostic accuracy of the.e.OS score.in pre.icting DNR de.isions in the.inte.sive.care.unit(ICU).Me.hods This study was conducte. at the.ICU of a te.tiary re.e.ral hospital in Saudi Arabia be.we.n March and May ***,we.calculate. e.OS score. for all e.igible.conse.utive.admissions afte. 48 h in the.ICU and re.orde. the.DNR *** ability of the.score.to pre.ict DNR was e.plore. using logistic ***'s ide.l cut-off value.was calculate. using the.De.ong me.hod,and diffe.e.t diagnostic accuracy me.sure. we.e.ge.e.ate. with corre.ponding 95%confide.ce.inte.vals(CIs).Re.ults We.e.rolle. 857 patie.ts,125 re.e.ve. a DNR orde. and 732 did *** ave.age.e.OS score.of DNR and non-DNR patie.ts was 28.2±10.7 and 15.2±9.7,*** score.as a pre.ictor of DNR orde.,had an are. unde. re.e.ve. ope.ator characte.istic(AUROC)curve.of 81.8%(95%CI:79.0 to 84.3,Pe.'s ide.l cut-off value.17 was associate. with a se.sitivity of 87.2(95%CI:80.0 to 92.5,Pe.ificity of 63.9(95%CI:60.3 to 67.4,Pe.pre.ictive.value.of 29.2(95%CI:24.6 to 33.8,Pe.ative.pre.ictive.value.of 96.7(95%CI:95.1 to 98.3,Phis study,the.e.OS score.pe.forme. we.l as a diagnostic te.t for patie.ts who will be.labe.e. as DNR during the.r ICU stay.A cut-off score.17 may he.p guide.clinical de.isions to withhold or comme.ce.re.uscitative.me.sure..

关键词： Do-not-re.uscitate.DNR) Re.uscitation Inte.sive.care.unit(ICU) Diagnostic accuracy Se.sitivity Spe.ificity

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