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Robust interface and excellent as-built mechanical properties of Ti–6Al–4V fabricated through laser-aided additive manufacturing with powder and wire

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 154-168页

作者： Fei Weng Guijun bi Youxiang Chew Shang Sui Chaolin Tan Zhenglin Du Jinlong Su Fern Lan Ng Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong Engineering&Technology Research Center for Superhard MaterialSchool of Materials Science and EngineeringShandong UniversityJinan 250061China Institute of Intelligent Manufacturing Guangdong Academy of SciencesGuangzhou 510095China Singapore Institute of Manufacturing Technology 5 Cleantech Loop636732Singapore

The feasibility of manufacturing Ti-6Al-4V samples through a combination of laser-aided additive manufacturing with powder(LAAM_(p))and wire(LAAM_(w))was explored.A process study was first conducted to successfully circumvent defects in Ti-6Al-4V deposits for LAAM_(p) and LAAM_(w),*** the optimized process parameters,robust interfaces were achieved between powder/wire deposits and the forged substrate,as well as between powder and wire *** characterization results revealed the epitaxial prior β grains in the deposited Ti-6Al-4V,wherein the powder deposit was dominated by a finerα′microstructure and the wire deposit was characterized by lamellar α *** mechanisms of microstructure formation and correlation with mechanical behavior were analyzed and *** mechanical properties of the interfacial samples can meet the requirements of the relevant Aerospace Material Specifications(AMS 6932)even without post heat *** fracture occurred within the interfacial area,further suggesting the robust *** findings of this study highlighted the feasibility of combining LAAM_(p) and LAAM_(w) in the direct manufacturing of Ti-6Al-4V parts in accordance with the required dimensional resolution and deposition rate,together with sound strength and ductility balance in the as-built condition.

关键词： laser-aided additive manufacturing powder deposition wire deposition interfacial characteristic mechanical behavior

Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats

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Neural Regeneration Research 2025年第4期20卷 1164-1177页

作者： Pengfei Wang Yuewei bi Min Li Jiazhi Chen Zhuyong Wang huantao Wen Ming Zhou Minjie Luo Wangming Zhang Neurosurgery Center Department of Pediatric NeurosurgeryGuangdong Provincial Key Laboratory on Brain Function Repair and RegenerationZhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

Long-term levodopa administration can lead to the development of levodopa-induced *** oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced ***,studies have reported increased oscillation power in cases of levodopa-induced ***,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced ***,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is *** found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s ***,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma *** of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum ***,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum *** findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia.

关键词： aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dyskinesia local field potentials neuromodulation Parkinson’s disease primary motor cortex

Interaction between Janus Green B and bovine serum albumin:Electrochemistry and spectroscopy studies

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Chinese Chemical Letters 2011年第6期22卷 717-720页

作者： Neslihan zdemir Serkan zdemir Ender bier Ondokuz Mayrs University Faculty of Arts and Sciences Department of Chemistry

In this study,voltammetric and spectroscopic investigation of the interaction between Janus Green B（JGB） and bovine serum albumin（BSA） was *** interaction was observed at Britton-Robinson buffer（ph 7.0）.When JGB was added to solution containing BSA,the peak currents of BSA decrease with the increasing of JGB concentrations which is due to the interaction of JGB and *** binding constant of JGB with BSA was obtained by voltammetric ***,this interaction was supported by means of UV-vis spectroscopic *** UV-vis absorption spectra of JGB in the presence of BSA decrease with the increasing of BSA concentrations.

关键词： Voltammetry Bovine serum albumin Janus Green B Interaction

Novel markers in predicting Brucella sacroiliitis:The platelet large cell ratio and basal immature reticulocyte fraction

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Asian Pacific Journal of Tropical Medicine 2023年第1期16卷 39-44页

作者： Neslihan Celik Esra Laloğlu hülya Aslan Depertmant of Infection Diseases and Clinical Microbiology Health Sciences University Erzurum Regional Education and Research HospitalErzurumYakutiyeTurkey Department of biochemistry Ataturk University School of Medicine25240ErzurumYakutiyeTurkey Depertmant of Microbiology Health Sciences University Erzurum Regional Education and Research HospitalErzurumYakutiyeTurkey

Objective:To present platelet large cell ratio(P-LCR),reticulocyte,and immature reticulocyte fraction(IRF)values as novel parameters in diagnosis and response to treatment in patients developing ***:Sixty-eight patients with clinical symptoms and Brucella standard tube agglutination(Wright)or Brucella Coombs agglutination test titers≥1:160 were included in the *** groups were established,one developing sacroiliitis and another with no sacroiliitis development.P-LCR,reticulocyte,and IRF levels were measured using a Sysmex XN-9000 device(Japan).These were then compared between the two ***:Reticulocyte(P=0.037)and IRF(P=0.026)levels were significantly lower among the patients developing sacroiliitis compared to the non-sacroiliitis group,while P-LCR(P=0.003)levels were significantly higher.P-LCR had the most powerful correlation with sacroiliitis *** negative correlation was observed between reticulocyte,IRF levels and ***:Elevated P-LCR levels were observed as a marker of persisting inflammation in patients developing sacroiliitis,while low reticulocyte and IRF levels secondary to bone marrow involvement were *** three parameters emerged as highly significant markers in terms of diagnosis and reflecting responses to treatment in organ involvement such as sacroiliitis in *** are presented as inexpensive,and easily accessible novel parameters.

关键词： Brucella sacroiliitis P-LCR Reticulocyte IRF

Surgery for hepatocellular carcinoma with tumor thrombosis in inferior vena cava: A case report

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World Journal of Clinical Cases 2021年第36期9卷 11495-11503页

作者： Zun-Yi Zhang er-Lei Zhang bi-Xiang Zhang Wei Zhang Research Laboratory and hepatic Surgery Center Department of Hepatic SurgeryTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000Hubei ProvinceChina

BACKGROUND hepatocellular carcinoma(hCC)accompanied by a tumor thrombus is very ***,the treatment strategy is controversial and varies by the location of the *** SUMMARY We report herein a case of hCC with a tumor thrombus in the suprahepatic inferior vena cava(IVC),which was successfully treated by hepatectomy combined with thrombectomy following sorafenib chemotherapy.A 47-year-old woman with chronic hepatitis was diagnosed with *** tomography and magnetic resonance imaging showed that the tumor lesion was located in the right half of the liver,and a tumor thrombus was detected in the suprahepatic IVC near the right *** multi-departmental discussion and patient informed consent,right major hepatectomy and total removal of the tumor thrombus were successfully performed under cardiopulmonary *** were no serious complications after *** sorafenib treatment,no recurrence has been detected so far(11 mo later).CONCLUSION Surgical treatment followed by adjuvant sorafenib therapy might be an acceptable choice for hCC patients with tumor thrombosis in the IVC.

关键词： hepatocellular carcinoma Tumor thrombosis Inferior vena cava hepatectomy Thrombectomy Sorafenib Cardiopulmonary bypass Case report

Optimization of regional nodal irradiation in the era of sentinel lymph node biopsy

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Cancer biology & Medicine 2023年第2期20卷 89-92页

作者： Zhao bi Xue’er Wang Pengfei Qiu Peng Chen Yongsheng Wang Shandong Cancer hospital and Institute Shandong First Medical University and Shandong Academy of Medical SciencesJinan 250017China Tianjin Medical University Cancer Institute&hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin's Clinical Research Center for CancerTianjin 300060China

historically,axillary lymph node dissection(ALND)was the standard management for axillary sentinel lymph node(SLN)-positive patients,because it enables full assessment of overall axillary lymph node(ALN)metastasis sta... 详细信息

关键词： lymph metastasis dissection

Corrosion behavior and mechanical properties of cold metal transfer welded dissimilar AA7075-AA5754 alloys

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Journal of Central South University 2020年第1期27卷 18-26页

作者： Nilay ??MEZ hülya DURMU? Manisa Celal Bayar University Metallurgical and Materials Engineering

Cold metal transfer(CMT) welding is a brand-new arc welding technique which shows adequate results for welding of thin sheets and dissimilar materials. Corrosion behavior of dissimilar aluminum joints should be determined in terms of predicting the effect of welding process on the possible failures in their constructions caused by corrosive agents. The present study investigates the effect of heat input on mechanical properties and corrosion rate of AA5754-AA7075 joints welded by CMT using er5356 filler wire. Pore formation was observed not only in the weld metal but also in the partially melted zone of AA7075 base metal due to the vaporization of zinc. Increased heat input caused over aging and zinc vaporization in AA7075 base metal, and grain coarsening in AA5754 base metal consequently decreased the tensile strength. The average tensile strength of AA7075-AA5754 joints varies between 235 and 240 MPa. The ductile fracture occurred at the AA5754 base metal side in all samples. Pitting was observed as the dominant corrosion mechanism. Corrosion resistance tended to increase with increasing heat input. heat input values between 95 and 110 J/mm are recommended for the optimization of corrosion resistance and strength.

关键词： AA5754 alloy AA7075 alloy aluminum corrosion Tafel tensile strength dissimilar welding

A case of post traumatic mitral chordae rupture mimicking acute respiratory distress syndrome

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World Journal of Emergency Medicine 2024年第4期15卷 322-324页

作者： hülya Deniz Misir Nalan Demir Ferit Kasimzade Cansu Yahşi Intensive Care Department Ankara Bilkent City HospitalAnkara 06800Turkiye Intensive Care Department University of Health Sciences Ankara Bilkent City HospitalAnkara 06800Turkiye Cardiovascular Surgery Department Ankara Bilkent City HospitalAnkara 06800Turkiye Pulmonary Medicine Department University of Health Sciences Ankara Bilkent City HospitalAnkara 06800Turkiye

Traumatic mitral chordae rupture is a rare and known cause of acute mitral valve regurgitation and de novo heart *** pathologies in a trauma patient may mask the findings of de novo heart failure due to mitral chordae *** patients may also have other potential pre-diagnoses that could explain symptoms related to heart failure,such as tachycardia,circulatory shock,and acute *** possibility of traumatic chordae tendinea rupture being a preventable cause of mortality should be carefully evaluated.

关键词： rupture mitral acute

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从家庭视角看中国女性劳动参与率的下降趋势

武汉大学学报（哲学社会科学版） 2025年第1期78卷 133-145页

作者：赵耀辉毕汝岱武汉大学武汉大学董辅礽经济社会发展研究院湖北武汉430072 北京大学国家发展研究院北京100091

随着社会经济的发展和人口结构的深刻调整,中国女性劳动参与率发生了显著变化。改革开放初期,中国女性劳动参与率显著高于欧美主要发达国家的水平,但近年来大幅下降,已接近其平均值。研究发现,已生育女性劳动参与率的下降是整体趋势的... 详细信息

随着社会经济的发展和人口结构的深刻调整,中国女性劳动参与率发生了显著变化。改革开放初期,中国女性劳动参与率显著高于欧美主要发达国家的水平,但近年来大幅下降,已接近其平均值。研究发现,已生育女性劳动参与率的下降是整体趋势的主要驱动力,而婚育模式的转变在一定程度上对这一趋势起到了缓冲作用。对于已婚女性而言,学龄前子女的照料负担逐渐成为劳动市场参与的核心制约因素。女性教育水平的提升通过禀赋和系数效应显著促进了劳动参与,但配偶教育水平的影响由正向转为负向,说明家庭收入能力的提高减弱了女性劳动参与的经济动机,强化了性别分工的传统趋势。优化育儿支持体系、促进性别平等以及营造职场友好环境,是缓解婚育负担对女性劳动市场参与约束的关键政策方向。

关键词：女性劳动参与率婚育模式育儿成本