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Proton irradiation-induced cracking and microstructural defects in UN and (U,Zr)N composite fuels

Journal of Materiomics 2024年第4期10卷 906-918页

作者： Elina Charatsidou Maria Giamouridou Andrea Fazi gyula nagy Diogo Ribeiro Costa Sarmad Naim Katea Mikael Jolkkonen Gunnar Westin Mattias Thuvander Daniel Primetzhofer Pär Olsson KTH Royal Institute of Technology StockholmSweden Chalmers University of Technology GothenburgSweden Uppsala University UppsalaSweden Westinghouse Electric Sweden AB VästeråsSweden Höganäs Sweden AB HöganäsSweden

Proton irradiation with a primary ion energy of 2 MeV was used to simulate radiation damage in UN and(U,Zr)N fuel *** pellets,nominally at room temperature,were irradiated to peak levels of 0.1,1,10 dpa and 100.0 dpa resulting in a peak hydrogen concentration of at most 90 at.%.Microstructure and mechanical properties of the samples were investigated and compared before and after *** irradiation induced an increase in hardness,whereas a decrease in Young’s modulus was observed for both *** characterization revealed irradiation-induced cracking,initiated in the bulk of the material,where the peak damage was deposited,propagating towards the ***,transmission electron microscopy was used to study irradiation *** loops and fringes were identified and observed to increase in density with increasing dose *** high density of irradiation defects and hydrogen implanted are proposed as the main cause of swelling and consequent sample cracking,leading simultaneously to increased hardening and a decrease in Young's modulus.

关键词： Proton irradiation Uranium nitride Spark plasma sintering Irradiation induced cracking Simulated burn-up structure Composite nuclear fuels

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Successful elimination of extended-spectrum beta-lactamase (ESBL)-producing nosocomial bacteria at a neonatal intensive care unit

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World Journal of Pediatrics 2017年第3期13卷 210-216页

作者： Borbála Szél Zsolt Reiger Edit Urbán Andrea Lázár Krisztina Mader Ivelina Damjanova Kamilla nagy gyula Tálosi Infection Control Unit University of SzegedHungary Department of Pediatrics University of SzegedHungary Institute of Clinical Microbiology University of SzegedHungary Department of Bacteriology National Center for EpidemiologyHungary

Background:Extended-spectrum beta-lactamase (ESBL)-producing Gram-negative bacteria are highly dangerous to *** our Neonatal Intensive Care Unit (NICU),the presence of these bacteria became so threatening in 2011 that immediate intervention was ***:This study was conducted during a nearly two-year period consisting of three phases:retrospective (9 months),educational (3 months) and prospective (9 months).Based on retrospective data analysis,a complex management plan was devised involving the introduction of the INSURE protocol,changes to the antibiotic regimen,microbiological screening at short intervals,progressive feeding,a safer bathing protocol,staff hand hygiene training and continuous monitoring of the number of newly infected and newly colonized *** these intervals,a total of 355 patients were ***:Both ESBL-producing Enterobacter cloaceae and Klebsiella pneumoniae were found (in both patients and environmental samples).In the prospective period a significant reduction could be seen in the average number of both colonized (26/167 patients;P=0.029) and infected (3/167 patients;P=0.033) patients compared to data from the retrospective period regarding colonized (72/188 patients) and infected (9/188 patients) *** was a decrease in the average number of patientdays (from 343.72 to 292.44 days per months),though this difference is not significant (P=0.058).During the prospective period,indirect hand hygiene compliance showed a significant increase (from the previous 26.02 to 33.6 hand hygiene procedures per patient per hospital day,P<0.001).Conclusion:Colonizations and infections were rolled back successfully in a multi-step effort that required an interdisciplinary approach.

关键词： hand hygiene INSURE protocol interdisciplinary approach neonates polyresistance

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用电流检测监控器和MOSFET提升输出电流

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电子设计技术 EDN CHINA 2009年第9期16卷 66-66页

作者： gyula Dioszegi János nagy 匈牙利布达佩斯Divelex有限公司

以前有篇设计实例描述了一种可编程电流源．使用的是美国国家半导体公司的LM317可调三端稳压器（参考文献1）。虽然该电路可以编程设定输出电流，但负载电流要流经BCD（二一十进制）开关。不过．你会发现很难买到能承受25mA以上电流的BC... 详细信息

以前有篇设计实例描述了一种可编程电流源．使用的是美国国家半导体公司的LM317可调三端稳压器（参考文献1）。虽然该电路可以编程设定输出电流，但负载电流要流经BCD（二一十进制）开关。不过．你会发现很难买到能承受25mA以上电流的BCD开关，这就限制了电路的输出电流。使用Zetex公司简单的四脚ZXCT1010电池检测监控芯片．可以提升电流．因为电流不再流经BCD开关（图1）。

关键词：输出电流 MOSFET 电流检测监控器美国国家半导体公司 Zetex公司三端稳压器 LM317

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采用NE555定时器的低成本电压/频率转换器

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电子设计技术 EDN CHINA 2008年第5期15卷 114-114页

作者： gyula Diózegi Jáos nagy 匈牙利布达佩斯Divelex有限公司

1971年，飞利浦公司的前身Signetics推出了NE555定时器．现在，制造商每年仍要提供超过10亿片这种产品。通过为NE555增加一些元件，可以建立一个不到50美分的简单电压／频率转换器。该转换器使用了由一只TL071组成的Miller积分器和～只N... 详细信息

1971年，飞利浦公司的前身Signetics推出了NE555定时器．现在，制造商每年仍要提供超过10亿片这种产品。通过为NE555增加一些元件，可以建立一个不到50美分的简单电压／频率转换器。该转换器使用了由一只TL071组成的Miller积分器和～只NE555定时器（图1）。此应用的输入电压范围为0V～10V，

关键词：电压/频率转换器 555定时器 NE555 低成本飞利浦公司电压范围制造商积分器

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Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: Phenotype-genotype correlations

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World Journal of Gastroenterology 2005年第10期11卷 1489-1495页

作者： Peter Laszlo Lakatos Laszlo Lakatos Ferenc Szalay Claudia Willheim-Polli Christoph (O|¨)sterreicher Zsolt Tulassay Tamas Molnar Walter Reinisch Janos Papp gyula Mozsik Hungarian IBD Study Group Peter Ferenci 1st Department of Medicine Laszlo Lakatos Department of Internal Medicine 4 2nd Department of Medicine Semmelweis University 2nd Department of MedicineSemmelweis UniversityBudapest:Laszlo PronaiAnnamaria NemethPal Miheller Erzsebet Hospital 1st Department of MedicineBudapest: Agota KovacsLaszlo Bene Szent Janos Hospital 1st Department of Medicine:Gyorgy Szekely University of Pecs 1st Department of MedicinePecs:Beata Gasztonyi University of Szeged 1st Department of MedicineSzeged:Ferenc NagyJanos Lonovics Semmelweis Hospital 1st Department of MedicineMiskolc:Laszlo Ujszaszy University of Debrecen 2nd Department of MedicineDebrecen:Istvan AltorjaiKaroly Palatka Kenezi Gy. County Hospital 2nd Department of MedicineDebrecen: Gyula G. Kiss County Hospital 2nd Department of MedicineZalaegerszeg Ferenc Tarnok Markusovszky Hospital2nd Department of MedicineSzombathely:Zoltan Dobronte Csolnoky F. County Hospital 1st Department of MedicineVeszprem:Zsuzsanna ErdelyiTunde PandurGabor Mester

AIM: To determine common NOD2/CARD15 mutations and TLR4 D299G polymorphism in Hungarian patients with CD. METHODS: A total of 527 unrelated patients with CD (male/female: 265/262, age: 37.1 (SD 7.6) years) and 200 healthy subjects were included. DNA was screened for possible NOD2/CARD15 mutations by denaturing high-performance liquid chromatography (confirmed by direct sequencing). TLR4 D299G was tested by PCR-RFLP. RESULTS: NOD2/CARD15 mutations were found in 185 patients (35.1%) and in 33 controls (16.5%,P<0.0001). SNP8/R702W (10.8% vs 6%, P= 0.02), SNP13/3020insC (19.4% vs 5%, P<0.0001) and exon4 R703C (2.1% vs 0%, P= 0.02) mutations were more frequent in CD, while the frequency of SNP12/G908R was not increased. The frequency of TLR4 D299G was not different (CD: 9.9% vs controls: 12.0%). Variant NOD2/CARD15 allele was associated with an increased risk for CD (ORhet=1.71, 95%CI=1.12-2.6, P= 0.0001, ORtwo-risk alleles = 25.2, 95%CI =4.37- ,P<0.0001), early disease onset (carrier: 26.4 years vs non-carrier: 29.8 years, P=0.0006), ileal disease (81.9% (?) 69.5%, OR = 1.99, 95%CI = 1.29-3.08, P= 0.02, presence of NOD2/CARD15 and TLR4: 86.7% vs 64.8%), stricturing behavior (OR = 1.69,95%CI = 1.13-2.55, P= 0.026) and increased need for resection (OR=1.71, 95%CI: 1.13-2.62, P= 0.01), but not with duration, extra-intestinal manifestations, familial disease or smoking. TLR4 exhibited a modifier effect: age of onset in wt/TLR4 D299G carriers: 27.4 years vs NOD2mut/TLR D299G: 23 years (P = 0.06), in NOD2mut/wt: 26.7 years. CONCLUSION: These results confirm that variant NOD2/ CARD15 (R702W, R703C and 3020insC) alleles are associated with earlier disease onset, ileal disease, stricturing disease behavior in Hungarian CD patients. In contrast, although the frequency of TLR4 D299G polymorphism was not different from controls, NOD2/TLR4 mutation carriers tended to present at earlier age.

关键词： Crohn's disease NOD2 CARD15 TLR4 Extraintestinal manifestation Phenotype

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