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Comparison of cytological and histological preparations in the diagnosis of pancreatic malignancies using endoscopic ultrasoundguided fine needle aspiration

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Hepatobiliary & Pancreatic Diseases International 2017年第4期16卷 418-423页

作者： Dong Kee Jang Sang Hyub lee Jun Kyu lee woo Hyun Paik Kwang Hyun Chung Ban Seok lee Jun Hyuk Son Jae woo lee Ji Kon Ryu Yong-Tae Kim Kyoung-Bun lee Department of Internal Medicine Dongguk University Ilsan Medical CenterGoyang-siGyeonggi-doKorea Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul National University College of MedicineSeoulKorea Department of Internal Medicine Inje University Ilsan Paik HospitalGoyang-siGyeonggi-doKorea Department of Pathology Seoul National University College of MedicineSeoulKorea

BACKGROUND:Endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) has become a crucial diagnostic technique for pancreatic *** specimen obtained by EUS-FNA can be prepared for either cytological or histological *** study was to compare diagnostic performance of cytological and histological preparations using EUSFNA in the same lesions when pancreatic malignancies were ***:One hundred and eighteen patients who underwent EUS-FNA for suspected pancreatic malignancies were consecutively *** procedures were conducted by a single echoendoscopist under the same *** adequate preparations were obtained by 22-gauge needles with 20 to-and-fro movements for each *** 4 preparations included 2 cytological and 2 histological *** pathologic reviews of all specimens were conducted independently by a single experienced ***,specificity,and accuracy of the 2 preparations were ***:The enrolled patients consisted of 62 males(52.5%),with the mean age of 64.6±10.5 *** was performed in 23(19.5%) *** hundred and sixteen(98.3%) lesions were classified as malignant,while 2(1.7%) were *** of cytology and histology were 87.9% and 81.9%,respectively,with no significant difference(P=0.190).Accuracy was also not significantly *** preparation was more sensitive when the size of lesion was <3 cm(86.7% vs 68.9%,P=0.033).CONCLUSIONS:Our results suggested that the diagnostic performances of cytological and histological preparations are not significantly different for the diagnosis of pancreatic ***,cytological preparation might be more sensitive for pancreatic lesions <3 cm.

关键词： endoscopic ultrasound-guided fine needle aspiration pancreatic neoplasms cytology pathology histology

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Crushed Gold Shell Nanoparticles Labeled with Radioactive Iodine as a Theranostic Nanoplatform for Macrophage-Mediated Photothermal Therapy

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Nano-Micro Letters 2019年第2期11卷 244-257页

作者： Sang Bong lee Jae-Eon lee Sung Jin Cho Jungwook Chin Sang Kyoon Kim In-Kyu lee Sang-woo lee Jaetae lee Yong Hyun Jeon New Drug Development Center Daegu-Gyeongbuk Medical Innovation FoundationDaeguSouth Korea Department of Biomaterials Science College of Natural Resources and Life Science/Life and Industry Convergence Research InstitutePusan National UniversityPusanSouth Korea Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease Kyungpook National University HospitalDaegu 702-210South Korea Department of Nuclear Medicine Kyungpook National University HospitalDaegu 702-210South Korea Department of Internal Medicine Kyungpook National University School of MedicineDaegu 700-721South Korea Daegu-Gyeongbuk Medical Innovation Foundation Daegu 360-4South Korea [Laboratory Animal Center Daegu-Gyeongbuk Medical Innovation FoundationDaegu 360-4South Korea

Plasmonic nanostructure-mediated photothermal therapy(PTT) has proven to be a promising approach for cancer treatment,and new approaches for its effective delivery to tumor lesions are currently being *** study aimed to assess macrophage-mediated delivery of PTT using radioiodine-124-labeled gold nanoparticles with crushed gold shells(124I-Au@AuCBs) as a theranostic nanoplatform.124I-Au@AuCBs exhibited effective photothermal conversion effects both in vitro and in vivo and were efficiently taken up by macrophages without *** the administration of 124I-Au@AuCB-labeled macrophages to colon tumors,intensive signals were observed at tumor lesions,and subsequent in vivo PTT with laser irradiation yielded potent antitumor *** results indicate the considerable potential of 124I-Au@AuCBs as novel theranostic nanomaterials and the prominent advantages of macrophage-mediated cellular therapies in treating cancer and other diseases.

关键词： Photothermal therapy Radionuclide crushed gold shell nanoballs Macrophage-mediated delivery

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Another new variant of Bouveret's syndrome

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World Journal of Gastroenterology 2009年第3期15卷 378-379页

作者： Seong-Heum Park Sang-woo lee Tae-Jin Song Department of Surgery Korea UniversityAnsan Hospital516Gojan-dongDanwon-guAnsanGyeonggi-do 425-707South Korea Department of Gastroenterology Korea UniversityAnsan Hospital516Gojan-dongDanwon-guAnsanGyeonggi-do 425-707South Korea

Although Bouveret's syndrome,*** outlet obstruction by a large gallstone impacted in the proximal duodenum secondary to a cholecystoduodenal fistula,is rare,its pathogenesis and clinical features are well ***,existence of variant forms of the syndrome are not well known,and as far as we know,only two cases of variant Bouveret's syndrome have been described in the English-language *** present a case of another new variant of Bouveret's syndrome in a 54-year-old Korean woman.

关键词： Duodenal obstruction Biliary fistula Gallstones

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Delusional parasitosis as premotor symptom of parkinson's disease:A case report

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World Journal of Clinical Cases 2022年第9期10卷 2858-2863页

作者： Miae Oh Jong woo Kim Sang-Min lee Department of Psychiatry Kyung Hee University HospitalKyung Hee University School of MedicineSeoul 02447South Korea

BACKGROUND Delusional parasitosis is characterized by a false belief of being infested with parasites,insects,or *** illness is observed in patients with Parkinson’s disease and is usually related to dopaminergic *** our knowledge,no cases of delusional parasitosis have been reported as a premotor symptom or nonmotor symptom of Parkinson’s *** SUMMARY A 75-year-old woman presented with a complaint of itching that she ascribed to the presence of insects in her skin,and she had erythematous plaques on her trunk,arms,buttocks,and *** symptoms started two months before the visit to the *** took medication,including antipsychotics,with a diagnosis of delusional parasitosis,and the delusion improved after three months.A year later,antipsychotics were discontinued,and anxiety and depression were controlled with ***,she complained of bradykinesia,masked face,hand tremor,and mild rigidity,and we performed fluorinated N-3-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane positron emission tomography(PET),which showed mildly decreased DAT binding in the right anterior putamen and caudate ***’s disease was diagnosed on the basis of PET and clinical *** In conclusion,delusional parasitosis can be considered a non-motor sign of Parkinson’s disease along with depression,anxiety,and constipation.

关键词： Delusional parasitosis Psychotic symptom Parkinson’s disease Nonmotor symptom Premotor symptom Case report

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Effects of Temperature on Photosynthetic Rates in Korean Fir (Abies koreana) between Healthy and Dieback Population

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Journal of Integrative Plant Biology 2008年第2期50卷 190-193页

作者： Su Young woo Jong-Hwan Lim Don Koo lee Department of Environmental Horticulture University of Seoul Seoul 130-743 Republic of Korea Korea Forest Research Institute Seoul 130-712Republic of Korea Department of Forest Sciences College of Agriculture and Life SciencesSeoul National UniversitySeoul 151-921Republic of Korea

The present study was carried out on natural Korean fir forests （Abies koreana） growing in Mount Halla in Jeju Island, Korea （33° 13-36＇ N and 126° 12-57＇ E）. Mount Halla is the highest mountain （1 950 m a.s.h） in South Korea. On the Korean fir forests near the top of Mount Halla in Korea, we established permanent plots between dieback and healthy population. Each permanent plot includes both dieback and relatively healthy Korean fir individuals. Three sites in this study showed similar altitude, topographic position, aspects, slope, diameter at breast height, average height and ages. Net photosynthetic rates （PN） on different temperature regimes were evaluated to explain the forest dieback phenomenon on Korean fir populations. Light response curves were determined on three different temperature regimes： 15 ℃, 20℃ and 25℃. The irradiance response curve showed higher values in lower air temperatures. Generally, irradiance response curves of healthy Korean fir populations were higher than the dieback population at all sites.

关键词： Abies koreana global warming forest decline photosynthetic rates temperature.

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Statistical Downscaling for Multi-Model Ensemble Prediction of Summer Monsoon Rainfall in the Asia-Pacific Region Using Geopotential Height Field

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Advances in Atmospheric Sciences 2008年第5期25卷 867-884页

作者：祝从文 Chung-Kyu PARK woo-Sung lee Won-Tae YUN Chinese Academy of Meteorological Sciences Asia-Pacific Economic Cooperation Climate Center (APCC) Busan Republic of Korea Canadian Centre for Climate Modelling and Reanalysis Victoria BC Canada Korea Meteorological Administration Seoul Republic of Korea

The 21-yr ensemble predictions of model precipitation and circulation in the East Asian and western North Pacific （Asia-Pacific） summer monsoon region （0°-50°N, 100° 150°E） were evaluated in nine different AGCM, used in the Asia-Pacific Economic Cooperation Climate Center （APCC） multi-model ensemble seasonal prediction system. The analysis indicates that the precipitation anomaly patterns of model ensemble predictions are substantially different from the observed counterparts in this region, but the summer monsoon circulations are reasonably predicted. For example, all models can well produce the interannual variability of the western North Pacific monsoon index （WNPMI） defined by 850 hPa winds, but they failed to predict the relationship between WNPMI and precipitation anomalies. The interannual variability of the 500 hPa geopotential height （GPH） can be well predicted by the models in contrast to precipitation anomalies. On the basis of such model performances and the relationship between the interannual variations of 500 hPa GPH and precipitation anomalies, we developed a statistical scheme used to downscale the summer monsoon precipitation anomaly on the basis of EOF and singular value decomposition （SVD）. In this scheme, the three leading EOF modes of 500 hPa GPH anomaly fields predicted by the models are firstly corrected by the linear regression between the principal components in each model and observation, respectively. Then, the corrected model GPH is chosen as the predictor to downscale the precipitation anomaly field, which is assembled by the forecasted expansion coefficients of model 500 hPa GPH and the three leading SVD modes of observed precipitation anomaly corresponding to the prediction of model 500 hPa GPH during a 19-year training period. The cross-validated forecasts suggest that this downscaling scheme may have a potential to improve the forecast skill of the precipitation anomaly in the South China Sea, western North Pacific and the East Asia

关键词： summer monsoon precipitation multi-model ensemble prediction statistical downscaling forecast

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Volume Estimation of Small Scale Debris Flows Based on Observations of Topographic Changes Using Airborne LiDAR DEMs

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Journal of Mountain Science 2014年第3期11卷 578-591页

作者： Hosung KIM Seung woo lee Chan-Young YUNE Gihong KIM Department of Civil Engineering Gangneung-Wonju National University

This paper describes a geographic information system(GIS)-based method for observing changes in topography caused by the initiation, transport, and deposition of debris flows using highresolution light detection and ranging(LiDAR) digital elevation models(DEMs) obtained before and after the debris flow events. The paper also describes a method for estimating the volume of debris flows using the differences between the LiDAR DEMs. The relative and absolute positioning accuracies of the LiDAR DEMs were evaluated using a real-time precise global navigation satellite system(GNSS) positioning method. In addition, longitudinal and cross-sectional profiles of the study area were constructed to determine the topographic changes caused by the debris flows. The volume of the debris flows was estimated based on the difference between the LiDAR DEMs. The accuracies of the relative and absolute positioning of the two LiDAR DEMs were determined to be ±10 cm and ±11 cm RMSE, respectively, which demonstrates the efficiency of the method for determining topographic changes at an scale equivalent to that of field investigations. Based on the topographic changes, the volume of the debris flows in the study area was estimated to be 3747 m3, which is comparable with the volume estimated based on the data from field investigations.

关键词： Debris flow Topographic change LiDAR DEM Volume estimation Global navigation satellitesystem (GNSS)

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Verification of Beam Models for Ionic Polymer-Metal Composite Actuator

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Journal of Bionic Engineering 2009年第3期6卷 232-238页

作者： Hoon Cheol Park Quoc Viet Nguyen Jang woo lee Young Tai Yoo Artificial Muscle Research Center Konkuk University Department of Advanced Technology Fusion Konkuk University Department of Materials Chemistry and Engineering Konkuk University

Ionic Polymer-Metal Composite (IPMC) can work as an actuator by applying a few voltages.A thick IPMC actuator,where Nafion-117 membrane was synthesized with polypyrrole/alumina composite filler,was analyzed to verify the equivalent beam and equivalent bimorph beam *** blocking force and tip displacement of the IPMC actuator were measured with a DC power supply and Young's modulus of the IPMC strip was measured by bending and tensile tests *** calculated maximum tip displacement and the Young's modulus by the equivalent beam model were almost identical to the corresponding measured *** element analysis with thermal analogy technique was utilized in the equivalent bimorph beam model to numerically reproduce the force-displacement relationship of the IPMC *** results by the equivalent bimorph beam model agreed well with the force-displacement relationship acquired by the measured *** is confirmed that the equivalent beam and equivalent bimorph beam models are practically and effectively suitable for predicting the tip displacement,blocking force and Young's modulus of IPMC actuators with different thickness and different composite of ionic polymer membrane.

关键词： jonic polymer-metal composite beam model displacement force

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Crushing behavior of lightmass structural member

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中国有色金属学会会刊：英文版 2009年第B9期19卷 276-279页

作者： Kil-Sung lee Yong-June YANG woo-Chae HWANG In-Young YANG Department of Mechatronics Chosun University of Science and Technology Department of Advanced Part and Materials Engineering Chosun University Department of Mechanical Design Engineering Chosun University

Carbon fiber reinforced plastic (CFRP) of the advanced composite materials is widely used in lightmass structural materials of air planes, ship and automobiles because of high strength and stiffness. In this study, experimental investigation was performed for each specimen. The square section members consist of aluminum, CFRP and hybrid (aluminum/CFRP) member, and hat-shaped section members consist of CFRP and hybrid (aluminum/CFRP) members specimen. Based on the collapse characteristics of aluminum square section member, the collapse characteristics and energy absorption capability of hat-shaped section members were analyzed. The axial static collapse tests were carried out for each section member. The collapse modes and the energy absorption capability of the members were analyzed. In the lightmass design aspect, the collapse characteristics and energy absorption capability of the members were compared.

关键词：碳纤维增强复合材料碳纤维复合材料能量吸收能力行为构件破碎航空飞机 CFRP

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Naphthalene emissions from moth repellents or toilet deodorant blocks determined using head-space and small-chamber tests

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Journal of Environmental Sciences 2008年第8期20卷 1012-1017页

作者： JO Wan-Kuen lee Jong-Hyo LIM Ho-Jin JEONG woo-Sik Department of Environmental Engineering Kyungpook National UniversityDaegu 702-701Korea. School of Food and Life Science Inje University KimhaeKyungsangnarado 621-749Korea

The present study investigated the emissions of naphthalene and other compounds from several different moth repellents(MRs) and one toilet deodorant block(TDB)currently sold in Korea,using a headspace *** emission factors and emission rates of naphthalene were studied using a small-scale environmental ***-type products emitted a higher concentration of the total volatile organic compounds(VOCs)(normalized to the weight of test piece)than ball-type products,which in turn emitted higher con...

关键词： volatile organic compounds(VOCs) chemical composition ball-type gel-type paper-type

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